메뉴 건너뛰기




Volumn 46, Issue 1, 1996, Pages 8-14

Recombinant Antibodies: Alternative Strategies for Developing and Manipulating Murine-Derived Monoclonal Antibodies

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; RECOMBINANT ANTIBODY; UNCLASSIFIED DRUG;

EID: 0029878036     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (69)
  • 1
    • 0022102126 scopus 로고
    • Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
    • Drebin, J. A., V. C. Link, D. F. Stern, et al. 1985. Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell 41:695-706.
    • (1985) Cell , vol.41 , pp. 695-706
    • Drebin, J.A.1    Link, V.C.2    Stern, D.F.3
  • 2
    • 0023279387 scopus 로고
    • Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: Immunologically mediated effector cell-independent effects
    • Rodeck, IL, M. Herlyn, D. Herlyn, et al. 1987. Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated effector cell-independent effects. Cancer Res. 47:3692-3696.
    • (1987) Cancer Res. , vol.47 , pp. 3692-3696
    • Rodeck, I.L.1    Herlyn, M.2    Herlyn, D.3
  • 3
    • 0027818836 scopus 로고
    • Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies
    • Fan, Z., H. Masui, I. Atlas, et al. 1993. Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res. 53:4322-4328.
    • (1993) Cancer Res. , vol.53 , pp. 4322-4328
    • Fan, Z.1    Masui, H.2    Atlas, I.3
  • 4
    • 0023943270 scopus 로고
    • Monoclonal antibodies specific for the neu oncogene product directly mediate anti-tumor effects in vivo
    • Drebin, J. A., V. C. Link, and M. I. Greene, 1988. Monoclonal antibodies specific for the neu oncogene product directly mediate anti-tumor effects in vivo. Oncogene 2:387-394.
    • (1988) Oncogene , vol.2 , pp. 387-394
    • Drebin, J.A.1    Link, V.C.2    Greene, M.I.3
  • 5
    • 0024313659 scopus 로고
    • Monoclonal antibodies for treating cancer
    • Dillman, R. O. 1989. Monoclonal antibodies for treating cancer. Ann. Intern. Med. 111:592-603.
    • (1989) Ann. Intern. Med. , vol.111 , pp. 592-603
    • Dillman, R.O.1
  • 6
    • 0025292826 scopus 로고
    • Monoclonal antibody therapy of lymphoproliferative disorders
    • Kuzel, T. M., J. N. Winter, S. T. Rosen, et al. 1990. Monoclonal antibody therapy of lymphoproliferative disorders. Oncology (Huntingt) 4:77-84.
    • (1990) Oncology (Huntingt) , vol.4 , pp. 77-84
    • Kuzel, T.M.1    Winter, J.N.2    Rosen, S.T.3
  • 7
    • 0022355587 scopus 로고
    • Human immune response to multiple injections of murine monoclonal IgG
    • Shawler, D. L., R. M. Bartholomew, L. M. Smith, et al. 1985. Human immune response to multiple injections of murine monoclonal IgG. J. Immunol. 135:1530-1535.
    • (1985) J. Immunol. , vol.135 , pp. 1530-1535
    • Shawler, D.L.1    Bartholomew, R.M.2    Smith, L.M.3
  • 8
    • 0021999401 scopus 로고
    • Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy
    • Schroff, R. W., K. A. Foon, S. M. Beatty, et al. 1985. Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy. Cancer Res. 45:879-885.
    • (1985) Cancer Res. , vol.45 , pp. 879-885
    • Schroff, R.W.1    Foon, K.A.2    Beatty, S.M.3
  • 9
    • 0025516520 scopus 로고
    • The antiglobulin response to therapeutic antibodies
    • Isaacs, J. D. 1990. The antiglobulin response to therapeutic antibodies. Semin. Immunol. 2:449-456.
    • (1990) Semin. Immunol. , vol.2 , pp. 449-456
    • Isaacs, J.D.1
  • 10
    • 0342701349 scopus 로고
    • Biological and clinical implications of lymphocyte hybridomas: Tumor therapy with monoclonal antibodies
    • Levy, R., and R. A. Miller. 1983. Biological and clinical implications of lymphocyte hybridomas: tumor therapy with monoclonal antibodies. Ann. Intern. Med. 14:1352-1359.
    • (1983) Ann. Intern. Med. , vol.14 , pp. 1352-1359
    • Levy, R.1    Miller, R.A.2
  • 11
    • 0024505574 scopus 로고
    • Delivery of novel therapeutic agents in tumors: Physiological barriers and strategies
    • Jain, R. 1989. Delivery of novel therapeutic agents in tumors: physiological barriers and strategies. J. Natl. Cancer Inst. 81:570-576.
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 570-576
    • Jain, R.1
  • 12
    • 11944273919 scopus 로고
    • Engineering antibodies for therapy
    • Adair, J. 1992. Engineering antibodies for therapy. Immunol. Rev. 130:5-40.
    • (1992) Immunol. Rev. , vol.130 , pp. 5-40
    • Adair, J.1
  • 13
    • 0026335705 scopus 로고
    • Construction of single-chain Fv derivatives of monoclonal antibodies and their production in Escherichia coli
    • Johnson, S., and R. E. Bird. 1991. Construction of single-chain Fv derivatives of monoclonal antibodies and their production in Escherichia coli. Methods Enzymol. 203:88-98.
    • (1991) Methods Enzymol. , vol.203 , pp. 88-98
    • Johnson, S.1    Bird, R.E.2
  • 14
    • 0026684815 scopus 로고
    • Rapid tumor penetration of single-chain Fv and comparison with other immunoglobulin forms
    • Yokota, T., D. E. Milenic, M. Whitlow, et al. 1992. Rapid tumor penetration of single-chain Fv and comparison with other immunoglobulin forms. Cancer Res. 52:3402-3408.
    • (1992) Cancer Res. , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3
  • 15
    • 0025362523 scopus 로고
    • In vivo tumor targeting of a recombinant single-chain antigen-binding protein
    • Colcher, D., R. Bird, M. Roselli, et al. 1990. In vivo tumor targeting of a recombinant single-chain antigen-binding protein. J. Natl. Cancer Inst. 82:1191-1197.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1191-1197
    • Colcher, D.1    Bird, R.2    Roselli, M.3
  • 16
    • 0023911111 scopus 로고
    • Reshaping human antibodies for therapy
    • Riechmann, L., M. Clark, H. Waldmann, et al. 1988. Reshaping human antibodies for therapy. Nature 332:323-327.
    • (1988) Nature , vol.332 , pp. 323-327
    • Riechmann, L.1    Clark, M.2    Waldmann, H.3
  • 17
    • 0024461313 scopus 로고
    • Binding activities of a repertoire of single immunoglobin variable domains secreted from Escherichia coli
    • Ward, E. S., D. Gussow, A. D. Griffiths, et al. 1989. Binding activities of a repertoire of single immunoglobin variable domains secreted from Escherichia coli. Nature 341:544-546.
    • (1989) Nature , vol.341 , pp. 544-546
    • Ward, E.S.1    Gussow, D.2    Griffiths, A.D.3
  • 18
    • 0014828908 scopus 로고
    • An analysis of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody diversity
    • Wu, T. E., and E. Rabat. 1970. An analysis of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody diversity. J. Exp. Med. 132:211.
    • (1970) J. Exp. Med. , vol.132 , pp. 211
    • Wu, T.E.1    Rabat, E.2
  • 19
    • 0024844388 scopus 로고
    • Conformations of immunoglobulin hypervariable regions
    • Chothia, C., A. M. Lesk, A. Tramontano, et al. 1989. Conformations of immunoglobulin hypervariable regions. Nature 342:877-883.
    • (1989) Nature , vol.342 , pp. 877-883
    • Chothia, C.1    Lesk, A.M.2    Tramontano, A.3
  • 21
    • 70449276523 scopus 로고
    • The hydrolysis of rabbit gamma-globulin and antibodies with crystalline papain
    • Porter, R. R. 1959. The hydrolysis of rabbit gamma-globulin and antibodies with crystalline papain. Biochem. J. 73:119.
    • (1959) Biochem. J. , vol.73 , pp. 119
    • Porter, R.R.1
  • 22
    • 1542698957 scopus 로고
    • Cloning immunoglobulin variable domains for expression by the polymerase chain reaction
    • Orlandi, R., D. H. Gussow, P. T. Jones, et al. 1989. Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA 86:3833-3837.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3833-3837
    • Orlandi, R.1    Gussow, D.H.2    Jones, P.T.3
  • 23
    • 0024833055 scopus 로고
    • Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
    • Huse, W., and R. Lerner. 1989. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 246:1275-1281.
    • (1989) Science , vol.246 , pp. 1275-1281
    • Huse, W.1    Lerner, R.2
  • 24
    • 0024845655 scopus 로고
    • Expression of functional antibody Fv and Fab fragments in Escherichia coli
    • Pluckthun, A., and A. Skerra. 1989. Expression of functional antibody Fv and Fab fragments in Escherichia coli. Methods Enzymol. 178:497-515.
    • (1989) Methods Enzymol. , vol.178 , pp. 497-515
    • Pluckthun, A.1    Skerra, A.2
  • 25
    • 0027347133 scopus 로고
    • Antibody engineering using Escherichia coli as host
    • Ward, E. S. 1993. Antibody engineering using Escherichia coli as host. Adv. Pharmacol. 24:1-20.
    • (1993) Adv. Pharmacol. , vol.24 , pp. 1-20
    • Ward, E.S.1
  • 26
    • 0026448976 scopus 로고
    • Bacterial single-chain antibody fragments, specific for carcinoembryonic antigen
    • Ayala, M., M. Duenas, A. Santos, et al. 1992. Bacterial single-chain antibody fragments, specific for carcinoembryonic antigen. Biotechniques 13:790-799.
    • (1992) Biotechniques , vol.13 , pp. 790-799
    • Ayala, M.1    Duenas, M.2    Santos, A.3
  • 27
    • 0027975979 scopus 로고
    • Intra- And extracellular expression of an scFv antibody fragment in E. coli: Effect of bacterial strains and pathway engineering using GroES/L chaperonins
    • Duenas, M., J. Vazques, M. Ayala, et al. 1994. Intra- and extracellular expression of an scFv antibody fragment in E. coli: effect of bacterial strains and pathway engineering using GroES/L chaperonins. BioTechniques 16:476-483.
    • (1994) BioTechniques , vol.16 , pp. 476-483
    • Duenas, M.1    Vazques, J.2    Ayala, M.3
  • 28
    • 0024293979 scopus 로고
    • Single-chain antigen-binding proteins
    • Bird, R. 1988. Single-chain antigen-binding proteins. Science 242:423-426.
    • (1988) Science , vol.242 , pp. 423-426
    • Bird, R.1
  • 29
    • 0026722822 scopus 로고
    • Diminution of antibodies directed against tumor cell surface epitopes: A single chain Fv fusion molecule specifically recognizes the extracellular domain of the c-erbB-2 receptor
    • Wels, W., I. M. Harwerth, N. E. Hynes, et al. 1992. Diminution of antibodies directed against tumor cell surface epitopes: a single chain Fv fusion molecule specifically recognizes the extracellular domain of the c-erbB-2 receptor. J. Steroid Biochem. Mol. Biol. 43(1-3):1-7.
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.43 , Issue.1-3 , pp. 1-7
    • Wels, W.1    Harwerth, I.M.2    Hynes, N.E.3
  • 30
    • 0026327378 scopus 로고
    • Construction, binding properties, metabolism, and tumor targeting of a single chain Fv derived from pancarcinoma monoclonal antibody CC49
    • Milenic, D. 1991. Construction, binding properties, metabolism, and tumor targeting of a single chain Fv derived from pancarcinoma monoclonal antibody CC49. Cancer Res. 51:6353-6371.
    • (1991) Cancer Res. , vol.51 , pp. 6353-6371
    • Milenic, D.1
  • 31
    • 0027420237 scopus 로고
    • Medical applications of single chain antibodies
    • Huston, J. 1993. Medical applications of single chain antibodies. Int. Rev. Immunol. 10:195-217.
    • (1993) Int. Rev. Immunol. , vol.10 , pp. 195-217
    • Huston, J.1
  • 32
    • 0021254542 scopus 로고
    • Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
    • Gill, G. N., T. Kawamoto, C. Cochet, et al. 1984. Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity. J. Biol. Chem. 259:7755-7760.
    • (1984) J. Biol. Chem. , vol.259 , pp. 7755-7760
    • Gill, G.N.1    Kawamoto, T.2    Cochet, C.3
  • 33
    • 0026486446 scopus 로고
    • Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor
    • Wels, W., I. M. Harwerth, M. Mueller, et al. 1992. Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor. Cancer Res. 52:6310-6317.
    • (1992) Cancer Res. , vol.52 , pp. 6310-6317
    • Wels, W.1    Harwerth, I.M.2    Mueller, M.3
  • 34
    • 0025122158 scopus 로고
    • A rapid method of cloning functional variable region antibody genes in Escherichia coli as single chain immunotoxins
    • Chaudhary, V. 1990. A rapid method of cloning functional variable region antibody genes in Escherichia coli as single chain immunotoxins. Proc. Natl. Acad. Sci. USA 87:1066-1070.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1066-1070
    • Chaudhary, V.1
  • 35
    • 0027218284 scopus 로고
    • Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates
    • Trail, P., D. Willner, S. Lasch, et al. 1993. Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates. Science 261:212-215.
    • (1993) Science , vol.261 , pp. 212-215
    • Trail, P.1    Willner, D.2    Lasch, S.3
  • 36
    • 0025875744 scopus 로고
    • Construction and expression of antibody-tumor necrosis factor fusion proteins
    • Hoogenboom, H. R., G. Volckaert, and J. C. Raus. 1991. Construction and expression of antibody-tumor necrosis factor fusion proteins. Mol. Immunol. 28:1027-1037.
    • (1991) Mol. Immunol. , vol.28 , pp. 1027-1037
    • Hoogenboom, H.R.1    Volckaert, G.2    Raus, J.C.3
  • 37
    • 0026585102 scopus 로고
    • Human c-erbB-2 proto-oncogene product as a target for bispecific-antibody-directed adoptive tumor immunotherapy
    • Nishimura, T., Y. Nakamura, H. Tsukamoto, et al. 1992. Human c-erbB-2 proto-oncogene product as a target for bispecific-antibody-directed adoptive tumor immunotherapy. Int. J. Cancer 50:800-804.
    • (1992) Int. J. Cancer , vol.50 , pp. 800-804
    • Nishimura, T.1    Nakamura, Y.2    Tsukamoto, H.3
  • 38
    • 0027388920 scopus 로고
    • A human tumor xenograft model of therapy with a bispecific monoclonal antibody targeting c-erbB2 and CD16
    • Weiner, L. M., M. Holmes, G. P. Adams, et al. 1993. A human tumor xenograft model of therapy with a bispecific monoclonal antibody targeting c-erbB2 and CD16. Cancer Res. 53:94-100.
    • (1993) Cancer Res. , vol.53 , pp. 94-100
    • Weiner, L.M.1    Holmes, M.2    Adams, G.P.3
  • 39
    • 0026604793 scopus 로고
    • Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene
    • Shalaby, M. R., M. Shepard, L. Presta, et al. 1992. Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene. J. Exp. Med. 175:217-225.
    • (1992) J. Exp. Med. , vol.175 , pp. 217-225
    • Shalaby, M.R.1    Shepard, M.2    Presta, L.3
  • 40
    • 0026633398 scopus 로고
    • Human breast cancer: Prognostic significance of the c-erbB-2 oncoprotein compared with epidermal growth factor receptor, DNA ploidy, and conventional pathologic features
    • Gasparini, G., W. J. Gullick, P. Bevilacqua, et al. 1992. Human breast cancer: prognostic significance of the c-erbB-2 oncoprotein compared with epidermal growth factor receptor, DNA ploidy, and conventional pathologic features. J. Clin. Oncol. 10:686-695.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 686-695
    • Gasparini, G.1    Gullick, W.J.2    Bevilacqua, P.3
  • 41
    • 0025823716 scopus 로고
    • Identical V region amino acid sequences and segments of sequences in antibodies of different specificities
    • Kabat, E. A., and T. T. Wu. 1991. Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. J. Immunol. 147:1709-1719.
    • (1991) J. Immunol. , vol.147 , pp. 1709-1719
    • Kabat, E.A.1    Wu, T.T.2
  • 43
    • 0025850422 scopus 로고
    • Design and synthesis of a mimetic of an antibody complementarity determining region
    • Saragovi, U., D. Fitzpatrick, A. Raktabuhr, et al. 1991. Design and synthesis of a mimetic of an antibody complementarity determining region. Science 253:792-795.
    • (1991) Science , vol.253 , pp. 792-795
    • Saragovi, U.1    Fitzpatrick, D.2    Raktabuhr, A.3
  • 44
    • 0025729547 scopus 로고
    • Design of bioactive peptides based on antibody hypervariable region structures
    • Williams, W. V., T. Kieber-Emmons, J. VonFeldt, et al. 1991. Design of bioactive peptides based on antibody hypervariable region structures. J. Biol. Chem. 266:5182-5190.
    • (1991) J. Biol. Chem. , vol.266 , pp. 5182-5190
    • Williams, W.V.1    Kieber-Emmons, T.2    Vonfeldt, J.3
  • 45
    • 0342530626 scopus 로고
    • Mouse/Human chimeric monoclonal antibody in man: Kinetics and immune response
    • LoBuglio, A., R. Wheeler, J. Trang. 1989. Mouse/Human chimeric monoclonal antibody in man: kinetics and immune response. Proc. Natl. Acad. Sci. USA 86:4220-4224.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 4220-4224
    • LoBuglio, A.1    Wheeler, R.2    Trang, J.3
  • 46
    • 0027520579 scopus 로고
    • Chimeric antibodies
    • Billetta, L. 1993. Chimeric antibodies. Int. Rev. Immunol. 10:165-176.
    • (1993) Int. Rev. Immunol. , vol.10 , pp. 165-176
    • Billetta, L.1
  • 47
    • 0025776895 scopus 로고
    • Pharmacokinetics, immune response, and biodistribution of iodine-131-labeled chimeric mouse/human IgG1,k 17-1A monoclonal antibody
    • Meredith, R. F., A. F. Lobuglio, W. E. Plott, et al. 1991. Pharmacokinetics, immune response, and biodistribution of iodine-131-labeled chimeric mouse/human IgG1,k 17-1A monoclonal antibody. J. Nucl. Med. 32:1162-1168.
    • (1991) J. Nucl. Med. , vol.32 , pp. 1162-1168
    • Meredith, R.F.1    Lobuglio, A.F.2    Plott, W.E.3
  • 48
    • 0025247828 scopus 로고
    • Mousehuman chimeric monoclonal antibody to carcinoembryonic antigen (CEA): In vitro and in vivo activities
    • Kang, H., K. Hidetoshi, M. Nakashima, et al. 1990. Mousehuman chimeric monoclonal antibody to carcinoembryonic antigen (CEA): in vitro and in vivo activities. Hybridoma 9:43-55.
    • (1990) Hybridoma , vol.9 , pp. 43-55
    • Kang, H.1    Hidetoshi, K.2    Nakashima, M.3
  • 49
    • 0025980998 scopus 로고
    • Preliminary studies for an immunotherapeutic approach to the treatment of human myeloma using chimeric anti-CD38 antibody
    • Stevenson, F. K., A. J. Bell, R. Cusak, et al. 1991. Preliminary studies for an immunotherapeutic approach to the treatment of human myeloma using chimeric anti-CD38 antibody. Blood 77:1071-1079.
    • (1991) Blood , vol.77 , pp. 1071-1079
    • Stevenson, F.K.1    Bell, A.J.2    Cusak, R.3
  • 50
    • 0025978976 scopus 로고
    • Man-made antibodies
    • Winter, G., and C. Milstein. 1991. Man-made antibodies. Nature 349:293-299.
    • (1991) Nature , vol.349 , pp. 293-299
    • Winter, G.1    Milstein, C.2
  • 51
    • 0026418194 scopus 로고
    • Humanized antibodies for therapy
    • Co, M. S., and C. Queen. 1991. Humanized antibodies for therapy. Nature 351:501-502.
    • (1991) Nature , vol.351 , pp. 501-502
    • Co, M.S.1    Queen, C.2
  • 52
    • 0023920595 scopus 로고
    • Reshaping human antibodies: Grafting an antilysozyme activity
    • Verhoeyen, M., C. Milstein, and G. Winter. 1988. Reshaping human antibodies: grafting an antilysozyme activity. Science 239:1534-1536.
    • (1988) Science , vol.239 , pp. 1534-1536
    • Verhoeyen, M.1    Milstein, C.2    Winter, G.3
  • 54
    • 0024204319 scopus 로고
    • Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody compath-1H
    • Hale, G., M. J. S. Dyer, M. R. Clark, et al. 1988 Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody compath-1H. Lancet 2(8625):1394-1399.
    • (1988) Lancet , vol.2 , Issue.8625 , pp. 1394-1399
    • Hale, G.1    Dyer, M.J.S.2    Clark, M.R.3
  • 55
    • 0026610881 scopus 로고
    • Humanization of an anti-p185/HER2 antibody for human cancer therapy
    • Carter, P., L. Presta, C. M. Gorman, et al. 1992. Humanization of an anti-p185/HER2 antibody for human cancer therapy. Proc. Natl. Acad. Sci. USA 89:4285-4289.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4285-4289
    • Carter, P.1    Presta, L.2    Gorman, C.M.3
  • 56
    • 0025270366 scopus 로고
    • Anti-Tac-H, a humanized antibody to the interleukin 2 receptor with new features for immunotherapy in malignant and immune disorders
    • Junghans, R. P., T. A. Waldmann, N. F. Landolfi, et al. 1990. Anti-Tac-H, a humanized antibody to the interleukin 2 receptor with new features for immunotherapy in malignant and immune disorders. Cancer Res. 50:1495-1502.
    • (1990) Cancer Res. , vol.50 , pp. 1495-1502
    • Junghans, R.P.1    Waldmann, T.A.2    Landolfi, N.F.3
  • 57
    • 0027078548 scopus 로고
    • Genetically engineered antibodies: Progress and prospects
    • Wright, A., S. U. Shin, and S. L. Morrison. 1992. Genetically engineered antibodies: progress and prospects. Grit. Rev. Immunol. 12:125-168.
    • (1992) Grit. Rev. Immunol. , vol.12 , pp. 125-168
    • Wright, A.1    Shin, S.U.2    Morrison, S.L.3
  • 58
    • 0027263741 scopus 로고
    • Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome
    • Choi, T. K., P. W. Hollenbach, B. E. Pearson, et al. 1993. Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome. Nat. Genet. 4:117-123.
    • (1993) Nat. Genet. , vol.4 , pp. 117-123
    • Choi, T.K.1    Hollenbach, P.W.2    Pearson, B.E.3
  • 59
    • 0027691148 scopus 로고
    • Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus
    • Taki, S., M. Meiering, and K. Rajewsky. 1993. Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus. Science 262:1268-1274.
    • (1993) Science , vol.262 , pp. 1268-1274
    • Taki, S.1    Meiering, M.2    Rajewsky, K.3
  • 60
    • 0025726654 scopus 로고
    • Human antibody production in transgenic mice: Expression from 100 kb of the human IgH locus
    • Bruggemann, M., C. Spicer, L. Buluwela, et al. 1991. Human antibody production in transgenic mice: expression from 100 kb of the human IgH locus. Eur. J. Immunol. 21:1323-1326.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1323-1326
    • Bruggemann, M.1    Spicer, C.2    Buluwela, L.3
  • 61
    • 0028308322 scopus 로고
    • Antibodies generated from human immunoglobulin miniloci in transgenic mice
    • Wagner, S. D., G. T. Williams, T. Larson, et al. 1994. Antibodies generated from human immunoglobulin miniloci in transgenic mice. Nucleic Acids Res 22:1389-1393.
    • (1994) Nucleic Acids Res , vol.22 , pp. 1389-1393
    • Wagner, S.D.1    Williams, G.T.2    Larson, T.3
  • 62
    • 0026641471 scopus 로고
    • Molecular evolution of proteins on filamentous phage
    • Marks, J. D., H. R. Hoogenboom, and G. Winter. 1992. Molecular evolution of proteins on filamentous phage. J. Biol. Chem. 267:16007-16010.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16007-16010
    • Marks, J.D.1    Hoogenboom, H.R.2    Winter, G.3
  • 63
    • 0026620529 scopus 로고
    • Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
    • Huse, W. D., L. Sastry, S. A. Iverson, et al. 1992. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Biotechnology 24:517-523,
    • (1992) Biotechnology , vol.24 , pp. 517-523
    • Huse, W.D.1    Sastry, L.2    Iverson, S.A.3
  • 64
    • 0026317443 scopus 로고
    • By-passing immunization: Human antibodies from V-gene libraries displayed on phage
    • Marks, J. D., H. R. Hoogenboom, T. P. Bonnert, et al. 1991. By-passing immunization: human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222:581-597.
    • (1991) J. Mol. Biol. , vol.222 , pp. 581-597
    • Marks, J.D.1    Hoogenboom, H.R.2    Bonnert, T.P.3
  • 65
    • 44949280863 scopus 로고
    • Combinatorial immunoglobulin libraries on the surface of phage (Phabs): Rapid selection of antigen specific Fabs
    • Barbas, C. F., and R. A. Lerner. 1991. Combinatorial immunoglobulin libraries on the surface of phage (Phabs): rapid selection of antigen specific Fabs. Methods 2:119-124.
    • (1991) Methods , vol.2 , pp. 119-124
    • Barbas, C.F.1    Lerner, R.A.2
  • 66
    • 0028006072 scopus 로고
    • Antibody fragments from a "single pot" phage display library as immunochemical reagents
    • Nissim, A., H. Hoogenboom, I. M. Tomlinson, et al. 1994. Antibody fragments from a "single pot" phage display library as immunochemical reagents. EMBO J. 13:692-398.
    • (1994) EMBO J. , vol.13 , pp. 692-1398
    • Nissim, A.1    Hoogenboom, H.2    Tomlinson, I.M.3
  • 67
  • 68
    • 0026486724 scopus 로고
    • Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity
    • Barbas, C. F., J. E. Crowe, D. Cababa, et al. 1992. Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity. Proc. Natl. Acad. Sci. USA 89:10164-10168.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10164-10168
    • Barbas, C.F.1    Crowe, J.E.2    Cababa, D.3
  • 69
    • 0026535931 scopus 로고
    • Selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library
    • Gram, H., L. Marconi, C. Barbas, et al. 1992. Selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library. In Vitro 89:3576-3580.
    • (1992) In Vitro , vol.89 , pp. 3576-3580
    • Gram, H.1    Marconi, L.2    Barbas, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.