메뉴 건너뛰기




Volumn 97, Issue 4, 1996, Pages 524-531

The enigma of common fragile sites

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; APHIDICOLIN; NUCLEASE; REPETITIVE DNA; ZINC FINGER PROTEIN;

EID: 0029878014     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02267080     Document Type: Article
Times cited : (40)

References (57)
  • 1
    • 0025140466 scopus 로고
    • Fragile site analysis: Its significance in environmental mutagenesis
    • Mendelsohn ML, Albertini RJ (eds) Wiley-Liss, New York
    • Ahuja YR (1990) Fragile site analysis: its significance in environmental mutagenesis. In: Mendelsohn ML, Albertini RJ (eds) Mutation and the Environment, part B. Progress in clinical and Bioloaical Research, Vol 340B. Wiley-Liss, New York, pp 371-384
    • (1990) Mutation and the Environment, Part B. Progress in Clinical and Bioloaical Research , vol.340 B , pp. 371-384
    • Ahuja, Y.R.1
  • 3
    • 0025833196 scopus 로고
    • Expression of common fragile sites on the X chromosome corresponds with active gene regions
    • Austin MJF (1991) Expression of common fragile sites on the X chromosome corresponds with active gene regions. Cancer Genet Cytogenet 54 : 71-76
    • (1991) Cancer Genet Cytogenet , vol.54 , pp. 71-76
    • Austin, M.J.F.1
  • 6
    • 0025914731 scopus 로고
    • Synergism between aphidicolin and adenoviruses in the induction of breaks at fragile sites on human chromosomes
    • Caporossi D, Bacchetti S, Nicoletti B (1991) Synergism between aphidicolin and adenoviruses in the induction of breaks at fragile sites on human chromosomes. Cancer Genet Cytogenet 54 : 39-53
    • (1991) Cancer Genet Cytogenet , vol.54 , pp. 39-53
    • Caporossi, D.1    Bacchetti, S.2    Nicoletti, B.3
  • 7
    • 0029013420 scopus 로고
    • Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments
    • Craddock CF, Vvas P, Sharpe JA, Ayyub H, Wood WG, Higgs DR (1995) Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments. EMBO J 14 : 1718-1726
    • (1995) EMBO J , vol.14 , pp. 1718-1726
    • Craddock, C.F.1    Vvas, P.2    Sharpe, J.A.3    Ayyub, H.4    Wood, W.G.5    Higgs, D.R.6
  • 9
    • 0023358242 scopus 로고
    • Variation in the expression of aphidicolin-induced fragile sites in human lymphocyte cultures
    • Craig-Holmes AP, Strong LC, Goodacre A, Pathak S (1987) Variation in the expression of aphidicolin-induced fragile sites in human lymphocyte cultures. Hum Genet 76 : 134-137
    • (1987) Hum Genet , vol.76 , pp. 134-137
    • Craig-Holmes, A.P.1    Strong, L.C.2    Goodacre, A.3    Pathak, S.4
  • 10
    • 0022596934 scopus 로고
    • Clinical implications and classification of the constitutive fragile sites
    • Daniel A (1986) Clinical implications and classification of the constitutive fragile sites. Am J Med Genet 23 : 419-427
    • (1986) Am J Med Genet , vol.23 , pp. 419-427
    • Daniel, A.1
  • 11
    • 0028833226 scopus 로고
    • Escape from X inactivation in human and mouse
    • Disteche CM (1995) Escape from X inactivation in human and mouse. Trends Genet 11 : 17-22
    • (1995) Trends Genet , vol.11 , pp. 17-22
    • Disteche, C.M.1
  • 12
    • 0019842812 scopus 로고
    • DNase 1-hypersensitive sites of chromatin
    • Elgin SCR (1981) DNase 1-hypersensitive sites of chromatin. Cell 27 : 413-415
    • (1981) Cell , vol.27 , pp. 413-415
    • Elgin, S.C.R.1
  • 13
    • 0026599021 scopus 로고
    • Chromatin as an essential part of the transcriptional mechanism
    • Felsenfeld G (1992) Chromatin as an essential part of the transcriptional mechanism. Nature 355 : 219-224
    • (1992) Nature , vol.355 , pp. 219-224
    • Felsenfeld, G.1
  • 14
    • 0028828902 scopus 로고
    • Increased chromosomal breakage in Tourette syndrome may be responsible for variable secondary gene involvement in complex neurobehavioural disorders: Preliminary findings and hypothesis
    • Gericke GS, Simonie I, Cloete E, Buckle C, Becker PJ (1995a) Increased chromosomal breakage in Tourette syndrome may be responsible for variable secondary gene involvement in complex neurobehavioural disorders: preliminary findings and hypothesis. Am J Med Genet 60 : 444-447
    • (1995) Am J Med Genet , vol.60 , pp. 444-447
    • Gericke, G.S.1    Simonie, I.2    Cloete, E.3    Buckle, C.4    Becker, P.J.5
  • 15
    • 0029964332 scopus 로고    scopus 로고
    • Increased expression of aphidicolin-induced common fragile sites in Tourette syndrome: The key to understanding the genetics of comorbid phenotypes?
    • Gericke GS, Simonic I, Cloete E, Becker PJ (1996) Increased expression of aphidicolin-induced common fragile sites in Tourette syndrome: the key to understanding the genetics of comorbid phenotypes? Am J Med Genet (in press)
    • (1996) Am J Med Genet (in Press)
    • Gericke, G.S.1    Simonic, I.2    Cloete, E.3    Becker, P.J.4
  • 16
    • 0021278143 scopus 로고
    • DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes
    • Glover TW, Berger C, Coyle J, Echo B (1984) DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes. Hum Genet 67 : 136-142
    • (1984) Hum Genet , vol.67 , pp. 136-142
    • Glover, T.W.1    Berger, C.2    Coyle, J.3    Echo, B.4
  • 17
    • 0021711842 scopus 로고
    • Characterization of genomic poly(dT-dG) poly (dC-dA) sequences. Structure, organisation and conformation
    • Hamada H, Petrino MG, Kakunaga T, Seidman M, Stollar BD (1984) Characterization of genomic poly(dT-dG) poly (dC-dA) sequences. Structure, organisation and conformation. Mol Cell Biol 4 : 2610-2621
    • (1984) Mol Cell Biol , vol.4 , pp. 2610-2621
    • Hamada, H.1    Petrino, M.G.2    Kakunaga, T.3    Seidman, M.4    Stollar, B.D.5
  • 18
    • 0022868406 scopus 로고
    • Rare, polymorphic, and common fragile sites: A classification
    • Hecht F (1986) Rare, polymorphic, and common fragile sites: a classification. Hum Genet 74 : 207-208
    • (1986) Hum Genet , vol.74 , pp. 207-208
    • Hecht, F.1
  • 19
    • 0023922439 scopus 로고
    • Fragile sites, cancer chromosome breakpoints, and oncogenes all cluster in light G bands
    • Hecht F (1988) Fragile sites, cancer chromosome breakpoints, and oncogenes all cluster in light G bands. Cancer Genet Cytogenet 31 : 17-24
    • (1988) Cancer Genet Cytogenet , vol.31 , pp. 17-24
    • Hecht, F.1
  • 20
    • 0025856651 scopus 로고
    • Biologic agents and induction of chromosome fragile sites
    • Hecht F (1991) Biologic agents and induction of chromosome fragile sites. Cancer Genet Cytogenet 54 : 127
    • (1991) Cancer Genet Cytogenet , vol.54 , pp. 127
    • Hecht, F.1
  • 22
    • 0025914050 scopus 로고
    • Sister chromatid exchanges are preferentially induced at expressed and nonexpressed common fragile sites
    • Hirsch B (1991) Sister chromatid exchanges are preferentially induced at expressed and nonexpressed common fragile sites. Hum Genet 87 : 302-306
    • (1991) Hum Genet , vol.87 , pp. 302-306
    • Hirsch, B.1
  • 23
    • 0024931988 scopus 로고
    • SCE enigma: Methodology, mechanism and meaning of sister chromatid exchange
    • Ikushima T (1989) SCE enigma: methodology, mechanism and meaning of sister chromatid exchange. Annu Rep Res Reactor Inst Kyoto Univ 22 : 57-77
    • (1989) Annu Rep Res Reactor Inst Kyoto Univ , vol.22 , pp. 57-77
    • Ikushima, T.1
  • 27
    • 0025167779 scopus 로고
    • Variability in expression of common fragile sites: In search of new criterion
    • Jordan DK, Burns TL, Devilbiss JE, Woolson RF, Patil SR (1990) Variability in expression of common fragile sites: in search of new criterion. Hum Genet 85 : 462-466
    • (1990) Hum Genet , vol.85 , pp. 462-466
    • Jordan, D.K.1    Burns, T.L.2    Devilbiss, J.E.3    Woolson, R.F.4    Patil, S.R.5
  • 29
    • 0023129735 scopus 로고
    • Synergistic effect of aphidicolin and ethanol on the induction of common fragile sites
    • Kuwano A, Kajii T (1987) Synergistic effect of aphidicolin and ethanol on the induction of common fragile sites. Hum Genet 75 : 75-78
    • (1987) Hum Genet , vol.75 , pp. 75-78
    • Kuwano, A.1    Kajii, T.2
  • 30
    • 0029039820 scopus 로고
    • Clinical evidence of genomic imprinting in Tourette's syndrome
    • Lichter DG, Jackson A, Schachter M (1995) Clinical evidence of genomic imprinting in Tourette's syndrome. Neurology 45 : 924-928
    • (1995) Neurology , vol.45 , pp. 924-928
    • Lichter, D.G.1    Jackson, A.2    Schachter, M.3
  • 31
    • 0026611669 scopus 로고
    • Clustering of C2-H2 zinc fonger motif sequences within telomeric and fragile sites regions of human chromosomes
    • Lichter P, Bray P, Ried T, Dawid IB, Ward DC (1992) Clustering of C2-H2 zinc fonger motif sequences within telomeric and fragile sites regions of human chromosomes. Genomics 13 : 999-1007
    • (1992) Genomics , vol.13 , pp. 999-1007
    • Lichter, P.1    Bray, P.2    Ried, T.3    Dawid, I.B.4    Ward, D.C.5
  • 32
    • 0022345121 scopus 로고
    • Fragile sites on human chromosomes: Description and clinical significance
    • Michels VV (1985) Fragile sites on human chromosomes: description and clinical significance.Mayo Clin Proc 60 : 690-696
    • (1985) Mayo Clin Proc , vol.60 , pp. 690-696
    • Michels, V.V.1
  • 33
    • 0023090923 scopus 로고
    • Fragile sites, chromosome evolution and human neoplasia
    • Miro R, Clemente IC, Fuster C, Egozcue J (1987) Fragile sites, chromosome evolution and human neoplasia. Hum Genet 75 : 345-349
    • (1987) Hum Genet , vol.75 , pp. 345-349
    • Miro, R.1    Clemente, I.C.2    Fuster, C.3    Egozcue, J.4
  • 34
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence specific DNA binding proteins
    • Mitchell PJ, Tjian R (1989) Transcriptional regulation in mammalian cells by sequence specific DNA binding proteins. Science 245 : 371-378
    • (1989) Science , vol.245 , pp. 371-378
    • Mitchell, P.J.1    Tjian, R.2
  • 36
    • 0024333576 scopus 로고
    • Fibroblast-specific common fragile sites induced by aphidicolin
    • Murano I, Kuwano A, Kajii T (1989a) Fibroblast-specific common fragile sites induced by aphidicolin. Hum Genet 83 : 45-48
    • (1989) Hum Genet , vol.83 , pp. 45-48
    • Murano, I.1    Kuwano, A.2    Kajii, T.3
  • 37
    • 0024811694 scopus 로고
    • Cell type-dependent difference in the distribution of aphidicolin-induced fragile sites: T and B lymphocytes and bone marrow cells
    • Murano I, Kuwano A, Kajii T (1989b) Cell type-dependent difference in the distribution of aphidicolin-induced fragile sites: T and B lymphocytes and bone marrow cells. Hum Genet 84 : 71-74
    • (1989) Hum Genet , vol.84 , pp. 71-74
    • Murano, I.1    Kuwano, A.2    Kajii, T.3
  • 39
    • 0028979332 scopus 로고
    • DNA polymerase links the DNA replication machinery to the S phase checkpoint
    • Navas TA, Zhou Z, Ellcdge SJ (1995) DNA polymerase links the DNA replication machinery to the S phase checkpoint. Cell 80 : 29-39
    • (1995) Cell , vol.80 , pp. 29-39
    • Navas, T.A.1    Zhou, Z.2    Ellcdge, S.J.3
  • 40
    • 0022610155 scopus 로고
    • Recombination and amplification of pyrimidine-rich sequences may be responsible for initiation and progression of the Xq27 fragile site: An hypothesis
    • Nussbaum RL, Airhart SD, Ledbetter DH (1986) Recombination and amplification of pyrimidine-rich sequences may be responsible for initiation and progression of the Xq27 fragile site: an hypothesis. Am J Med Genet 23 : 715-721
    • (1986) Am J Med Genet , vol.23 , pp. 715-721
    • Nussbaum, R.L.1    Airhart, S.D.2    Ledbetter, D.H.3
  • 41
    • 0018712819 scopus 로고
    • Mutagenic. carcinogenic and teratogenic effects of alcohol
    • Obe G, Ristow H (1979) Mutagenic. carcinogenic and teratogenic effects of alcohol. Mutat Res 65 : 229-259
    • (1979) Mutat Res , vol.65 , pp. 229-259
    • Obe, G.1    Ristow, H.2
  • 43
    • 0024369087 scopus 로고
    • The distribution of MspI-induced breaks in human lymphocyte chromosomes and its relationship to common fragile sites
    • Porfirio B, Tedeschi B, Vemole P, Caporossi D, Nicoletti B (1989) The distribution of MspI-induced breaks in human lymphocyte chromosomes and its relationship to common fragile sites. Mutat Res 213 : 117-124
    • (1989) Mutat Res , vol.213 , pp. 117-124
    • Porfirio, B.1    Tedeschi, B.2    Vemole, P.3    Caporossi, D.4    Nicoletti, B.5
  • 44
    • 0027437257 scopus 로고
    • The pseudoautosomal regions of the human sex chromosomes
    • Rappold GA (1993) The pseudoautosomal regions of the human sex chromosomes. Hum Genet 92 : 315-324
    • (1993) Hum Genet , vol.92 , pp. 315-324
    • Rappold, G.A.1
  • 45
    • 0021119770 scopus 로고
    • The chemistry and biology of left-handed Z-DNA
    • Rich A, Nordheim A, Wang AHJ (1984) The chemistry and biology of left-handed Z-DNA. Annu Rev biochem 53 : 791-856
    • (1984) Annu Rev Biochem , vol.53 , pp. 791-856
    • Rich, A.1    Nordheim, A.2    Wang, A.H.J.3
  • 46
    • 0026771276 scopus 로고
    • The highest gene concentration in the human genome are in telomeric bands of metaphase chromosomes
    • Saccone S, De Sario A, Della Valle G, Bemardi G (1992) The highest gene concentration in the human genome are in telomeric bands of metaphase chromosomes. Proc Natl Acad Sci USA 89 : 4913-1917
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4913-11917
    • Saccone, S.1    De Sario, A.2    Della Valle, G.3    Bemardi, G.4
  • 47
    • 0027460384 scopus 로고
    • Segregation analysis of rare autosomal folate sensitive fragile sites
    • Samadder P, Evans JA, Chudley AE (1993) Segregation analysis of rare autosomal folate sensitive fragile sites. Am J Med Genet 46 : 165-171
    • (1993) Am J Med Genet , vol.46 , pp. 165-171
    • Samadder, P.1    Evans, J.A.2    Chudley, A.E.3
  • 48
    • 0025200706 scopus 로고
    • Neither age nor sex influence the expression of folate sensitive common fragile sites on human chromosomes
    • Smeets DFCM, Merkx G (1990) Neither age nor sex influence the expression of folate sensitive common fragile sites on human chromosomes. Hum Genet 86 : 76-78
    • (1990) Hum Genet , vol.86 , pp. 76-78
    • Smeets, D.F.C.M.1    Merkx, G.2
  • 49
    • 0001691881 scopus 로고
    • The enigma of the fragile X chromosome
    • Sutherland GR (1985) The enigma of the fragile X chromosome. Trend Genet 1 : 108-112
    • (1985) Trend Genet , vol.1 , pp. 108-112
    • Sutherland, G.R.1
  • 50
    • 0023746743 scopus 로고
    • The role of nucleotides in human fragile site expression
    • Sutherland GR (1988) The role of nucleotides in human fragile site expression. Mutat Res 200 : 207-213
    • (1988) Mutat Res , vol.200 , pp. 207-213
    • Sutherland, G.R.1
  • 52
    • 0023180656 scopus 로고
    • Common fragile sites: Their prevalence in subjects with constitutional and acquired chromosomal instability
    • Tedeschi B, Porfirio B, Vernole P, Caporossi D, Dallapicolla B, Nicoletti B (1987) Common fragile sites: their prevalence in subjects with constitutional and acquired chromosomal instability. Am J Med Genet 27 : 471-482
    • (1987) Am J Med Genet , vol.27 , pp. 471-482
    • Tedeschi, B.1    Porfirio, B.2    Vernole, P.3    Caporossi, D.4    Dallapicolla, B.5    Nicoletti, B.6
  • 53
    • 0025829091 scopus 로고
    • Structural chromosomal rearrangements in HpaII-treated human lymphocytes
    • Tedeschi B, Porfirio B, Caporossi D, Nicoleni B (1991) Structural chromosomal rearrangements in HpaII-treated human lymphocytes. Mutat Res 248 : 115-121
    • (1991) Mutat Res , vol.248 , pp. 115-121
    • Tedeschi, B.1    Porfirio, B.2    Caporossi, D.3    Nicoleni, B.4
  • 54
    • 0026702607 scopus 로고
    • Population cytogenetics of aphidicolin-induced fragile sites
    • Tedeschi B, Vernole P, Lucia Sanna M, Nicoletti B (1992) Population cytogenetics of aphidicolin-induced fragile sites. Hum Genet 89 : 543-547
    • (1992) Hum Genet , vol.89 , pp. 543-547
    • Tedeschi, B.1    Vernole, P.2    Lucia Sanna, M.3    Nicoletti, B.4
  • 55
    • 0025915825 scopus 로고
    • Induction of distamycin A-inducible rare fragile sites and increased sister chromatid exchanges at fragile sites
    • Tsuji H, Hitomi A, Takahashi E, Murata M, Ikeuchi T, Yamamoto K, Tsuji S, Hori T (1991) Induction of distamycin A-inducible rare fragile sites and increased sister chromatid exchanges at fragile sites. Hum Genet 87 : 254-260
    • (1991) Hum Genet , vol.87 , pp. 254-260
    • Tsuji, H.1    Hitomi, A.2    Takahashi, E.3    Murata, M.4    Ikeuchi, T.5    Yamamoto, K.6    Tsuji, S.7    Hori, T.8
  • 57
    • 0025189579 scopus 로고
    • Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromalin folding code"
    • Vogt P (1990) Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromalin folding code". Hum Genet 84 : 301-336
    • (1990) Hum Genet , vol.84 , pp. 301-336
    • Vogt, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.