Genetic modification of plants: Significant issues and hurdles to success

American Journal of Clinical Nutrition

Volumn 63, Issue 4, 1996, Pages

  Day, Peter R ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

allergens; fatty acids; genetically engineered foods; phytase; plant breeding; Plant transformation; toxicants

Indexed keywords

AGRICULTURE; CONFERENCE PAPER; CROP; FOOD INDUSTRY; GENETIC ENGINEERING; PLANT;

EID: 0029877669     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/63.4.651     Document Type: Conference Paper

References (34)

1. Avery OT, MacLeod CM, McCarty M. Studies on the chemical nature of the substance inducing transformation of pneumococcus types. J Exp Med 1944;79:137-58.
2. Horsch RB, Fraley RT, Rogers SG, et al. Agrobacterium-mediated gene transfer to plants: engineering tolerance to glyphosate. Iowa State J Res 1988;62:487-502.
3. Hattori J, Rutledge R, Labbé H, Brown D, Sunohara G, Miki B. Multiple resistance to sulfonylureas and imidazolinones conferred by an acetohydroxyacid synthase gene with separate mutations for selective resistance. Mol Gen Genet 1992;232:167-73.
4. De Block M, Botterman J, Vandewiele M, et al. Engineering herbicide resistance in plants by expression of a detoxifying enzyme. EMBO J 1987;6:2513-8.
5. Newhouse K, Singh B, Shaner D, Stidham M. Mutations in corn (Zea mays L) conferring resistance to imidazolinone herbicides. Theor Appl Genet 1991;83:65-70.
6. Moffat AS. Mapping the sequence of disease resistance. Science 1994;265:1804-5.
7. Gill SS, Cowles EA, Pietrantonio PV. The mode of action of Bacillus thuringiensis endotoxins. Annu Rev Entomol 1992;37:615-36.
8. Hama H, Suzuki K, Tanaka H. Inheritance and stability of resistance to Bacillus thuringiensis formulations of the diamondback moth, Plutella xylostella (Linnaeus) (Lepidoptera:Yponomeutidae). Appl Entomol Zool 1992;27:355-62.
9. Hilder VA, Gatehouse AMR, Sheerman SE, Barker RF, Boulter D. A novel mechanism of insect resistance engineered into tobacco. Nature 1987;330:160-3.
10. Abel PP, Nelson RS, De B, et al. Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene. Science 1986;232:738-43.
11. Tumer NE, O'Connell KM, Nelson RS, et al. Expression of alfalfa mosaic virus coat protein gene confers cross-protection in transgenic tobacco and tomato plants. EMBO J 1987;6:1181-8.
12. Tricoli DM, Carney KJ, Quemada H, et al. Transgenic squash plants exhibit protein mediated protection under field conditions. J Cell Biochem Suppl 1992;16:222(abstr).
13. Golemboski BB, Lomonossoff GP, Zaitlin M. Plants transformed with a tobacco mosaic nonstructural gene sequence are resistant to the virus. Proc Natl Acad Sci U S A 1990;87:6311-5.
14. Cooper B, Lapidot M, Heick JA, Beachy RN, Dodds JA. Multi-virus resistance in transgenic tobacco plants expressing a tobacco mosaic virus dysfunctional movement protein. In: Scientific program and abstracts of the 13th annual meeting of the American Society for Virology. Madison, WI: American Society for Virology, 1994:250 (abstr).
15. Lodge JK, Kaniewski WK, Tumer NE. Broad-spectrum virus resistance in transgenic plants expressing pokeweed antiviral protein. Proc Natl Acad Sci U S A 1993;90:7089-93.
16. Benhamou N, Broglie K, Broglie R, Chet I. Antifungal effect of bean endochitinase on Rhizoctonia solani: ultrastructural changes and cytochemical aspects of chitin breakdown. Can J Microbiol 1993;39: 318-28.
17. Briggs SP. Identification and isolation of agronomically important genes from plants. In: Stalker HT, Murphy JP, eds. Plant breeding in the 1990s. Wallingford, CT: CAB International, 1992:373-87.
18. Beers S, Jongbloed AW. Effect of supplementary Aspergillus niger phytase in diets for piglets on their performance and apparent digestibility of phosphorus. Anim Prod 1992;55:425-30.
19. Pen J, Verwoerd TC, van Paridon PA, et al. Phytase-containing transgenic seeds as a novel feed additive for improved phosphorus utilization. Biotechnology (N Y) 1993;11:811-4.
20. Findenegg GR, Nelemans JA. The effect of phytase on the availability of P from myo-inositol hexaphosphate (phytate) for maize roots. Plant Soil 1993;154:189-96.
21. Howden R, Anderson CR, Goldsbrough PB, Cobbett CS. Cadmium sensitive, glutathione-deficient mutant of Arabidopsis thaliana. Plant Physiol 1995;107:1067-76.
22. Castro GA, Arntzen CJ. Immunophysiology of the gut: a research frontier for integrative studies of the common mucosal immune system. Am J Physiol 1993;265:G599-610.
23. Mason HS, Lam DM-K, Arntzen CJ. Expression of hepatitis B surface antigen in transgenic plants. Proc Natl Acad Sci U S A 1992;89: 11745-9.
24. Somerville CR. Future prospects for genetic modification of the composition of edible oils from higher plants. Am J Clin Nutr 1993; 58(suppl):270S-5S.
25. Ohlrogge JB. Design of new plant products: engineering of fatty acid metabolism. Plant Physiol 1994;104:821-6.
26. Nishio T, Iida S. Mutants having a low content of 16-kDa allergenic protein in rice (Oryza sativa L). Theor Appl Genet 1993;86:317-21.
27. Izumi H, Adachi T, Fujii N, et al. Nucleotide sequence of a cDNA clone encoding a major allergenic protein in rice seeds: homology of the deduced amino acid sequence with members of α-amylase/trypsin inhibitor family. FEBS Lett 1992;302:213-6.
28. Altenbach SB, Kuo C-C, Staraci LC, et al. Accumulation of a Brazil nut albumin in seeds of transgenic canola results in enhanced levels of seed protein methionine. Plant Mol Biol 1992;18:235-45.
29. Nordlee JA, Taylor SL, Townsend JA, Thomas LA. High methionine Brazil nut protein binds human IgE. J Allergy Clin Immunol 1994;93: 209(abstr).
30. Colot V, Bartels D, Thompson R, Flavel R. Molecular characterization of an active wheat LMW glutenin gene and its relation to other wheat and barley prolamin genes. Mol Gen Genet 1989;216:81-90.
31. Meyerowitz EM. Introduction to the Arabidopsis genome. In: Koncz C, Chua N-H, Schell J, eds. Methods in Arabidopsis research. Singapore: World Scientific Publishing Co, 1992:100-18.
32. Meyerowitz EM. The genetics of flower development. Sci Am 1994; 271(Nov):56-65.
33. Flavell RB. The value of model systems for the future plant breeder. In: Stalker HT, Murphy JP, eds. Plant breeding in the 1990s. Wallingford, CT: CAB International, 1992:409-19.
34. Hoban TJ IV. Anticipating public reaction to the use of genetic engineering in infant nutrition. Am J Clin Nutr 1996;63:657S-62S