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Volumn 63, Issue 4, 1996, Pages 532-545

Twenty-four-hour intravenous and oral tracer studies with L-[1-13C]phenylalanine and L-[3,3-2H2]tyrosine at a tyrosine-free, generous phenylalanine intake in adults

Author keywords

Diurnal rhythm; Indispensable amino acid requirements; Phenylalanine balance; Phenylalanine hydroxylation; Phenylalanine oxidation; Plasma phenylalanine concentration; Stable isotopes

Indexed keywords

PHENYLALANINE; TYROSINE;

EID: 0029877656     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/63.4.532     Document Type: Article
Times cited : (34)

References (56)
  • 1
    • 0024379317 scopus 로고
    • A theoretical basis for increasing current estimates of the amino acid requirements in adult man, with experimental support
    • Young VR, Bier DM, Pellett PL. A theoretical basis for increasing current estimates of the amino acid requirements in adult man, with experimental support. Am J Clin Nutr 1989;50:80-92.
    • (1989) Am J Clin Nutr , vol.50 , pp. 80-92
    • Young, V.R.1    Bier, D.M.2    Pellett, P.L.3
  • 2
    • 0025052043 scopus 로고
    • Mechanisms and nutritional significance of metabolic responses to altered intakes of protein and amino acids, with reference to nutritional adaptation in humans
    • Young VR, Marchini JS. Mechanisms and nutritional significance of metabolic responses to altered intakes of protein and amino acids, with reference to nutritional adaptation in humans. Am J Clin Nutr 1990; 51:270-89.
    • (1990) Am J Clin Nutr , vol.51 , pp. 270-289
    • Young, V.R.1    Marchini, J.S.2
  • 3
    • 0028141935 scopus 로고
    • Adult amino acid requirements: The case for a major revision in current recommendations
    • Young VR. Adult amino acid requirements: the case for a major revision in current recommendations. J Nutr 1994;124:1517S-23S.
    • (1994) J Nutr , vol.124
    • Young, V.R.1
  • 4
    • 0027427402 scopus 로고
    • Requirements for indispensable amino acids in adult humans: Longer-term amino acid kinetic study with support for the adequacy of the Massachusetts Institute of Technology amino acid requirement pattern
    • Marchini JS, Cortiella J, Hiramatsu T, Chapman TE, Young VR. Requirements for indispensable amino acids in adult humans: longer-term amino acid kinetic study with support for the adequacy of the Massachusetts Institute of Technology amino acid requirement pattern. Am J Clin Nutr 1993;58:670-83.
    • (1993) Am J Clin Nutr , vol.58 , pp. 670-683
    • Marchini, J.S.1    Cortiella, J.2    Hiramatsu, T.3    Chapman, T.E.4    Young, V.R.5
  • 6
    • 0028216060 scopus 로고
    • The 24-h pattern and rate of leucine oxidation, with particular reference to tracer estimates of leucine requirements in healthy adults
    • El-Khoury AE, Fukagawa NK. Sánchez M, et al. The 24-h pattern and rate of leucine oxidation, with particular reference to tracer estimates of leucine requirements in healthy adults. Am J Clin Nutr 1994;59: 1012-20.
    • (1994) Am J Clin Nutr , vol.59 , pp. 1012-1020
    • El-Khoury, A.E.1    Fukagawa, N.K.2    Sánchez, M.3
  • 7
    • 0347137654 scopus 로고
    • Metabolic basis of nutritional care in liver and kidney disease
    • Winters RW, Greene HL, eds. New York: Academic Press
    • Munro HN. Metabolic basis of nutritional care in liver and kidney disease. In: Winters RW, Greene HL, eds. Nutritional support of the seriously ill patient. New York: Academic Press, 1983:93-105.
    • (1983) Nutritional Support of the Seriously Ill Patient , pp. 93-105
    • Munro, H.N.1
  • 8
    • 0002371335 scopus 로고
    • The biochemistry and physiology of protein and amino acid metabolism, with reference to protein nutrition
    • Räihä NCR, ed. Protein metabolism during infancy New York: Raven Press
    • Young VR, El-Khoury AE, Sánchez M, Castillo L. The biochemistry and physiology of protein and amino acid metabolism, with reference to protein nutrition. In: Räihä NCR, ed. Protein metabolism during infancy. Nestlé Nutrition Workshop Series, Vol 33. New York: Raven Press, 1994:1-27.
    • (1994) Nestlé Nutrition Workshop Series , vol.33 , pp. 1-27
    • Young, V.R.1    El-Khoury, A.E.2    Sánchez, M.3    Castillo, L.4
  • 9
    • 0002222409 scopus 로고
    • Enzymatic basis for adaptive changes in amino acid metabolism
    • Taylor TG, Jenkins WK, eds. London: John Libbey & Co, Ltd
    • Harper AE. Enzymatic basis for adaptive changes in amino acid metabolism. In: Taylor TG, Jenkins WK, eds. Proceedings of the XIII International Congress of Nutrition. London: John Libbey & Co, Ltd, 1986:409-14.
    • (1986) Proceedings of the XIII International Congress of Nutrition , pp. 409-414
    • Harper, A.E.1
  • 10
    • 0028817723 scopus 로고
    • Phenylalanine and tyrosine kinetics in young men throughout a continuous 24-h period, at a low phenylalanine intake
    • Sánchez M, El-Khoury AE, Castillo L, Chapman TE, Young VR. Phenylalanine and tyrosine kinetics in young men throughout a continuous 24-h period, at a low phenylalanine intake. Am J Clin Nutr 1995;61:555-70
    • (1995) Am J Clin Nutr , vol.61 , pp. 555-570
    • Sánchez, M.1    El-Khoury, A.E.2    Castillo, L.3    Chapman, T.E.4    Young, V.R.5
  • 11
    • 0022292348 scopus 로고
    • Energy and protein requirements. Report of a joint FAO/WHO/UNU expert consultation
    • Food and Agriculture Organization/World Health Organization/United Nations University (FAO/WHO/UNU). Energy and protein requirements. Report of a joint FAO/WHO/UNU expert consultation. World Health Organ Tech Rep Ser 1985;724.
    • (1985) World Health Organ Tech Rep Ser , pp. 724
  • 12
    • 0023738108 scopus 로고
    • Leucine kinetics at graded intakes in young men: Quantitative fate of dietary leucine
    • Cortiella J, Matthews DE, Hoerr RA, Bier DM, Young VR. Leucine kinetics at graded intakes in young men: quantitative fate of dietary leucine. Am J Clin Nutr 1988;48:998-1009.
    • (1988) Am J Clin Nutr , vol.48 , pp. 998-1009
    • Cortiella, J.1    Matthews, D.E.2    Hoerr, R.A.3    Bier, D.M.4    Young, V.R.5
  • 14
    • 0027418638 scopus 로고
    • Effects of protein restriction and acute refeeding on leucine and lysine kinetics in young men
    • Hoerr RA, Matthews DE, Bier DM, Young VR. Effects of protein restriction and acute refeeding on leucine and lysine kinetics in young men. Am J Physiol 1993;264:E567-75.
    • (1993) Am J Physiol , vol.264
    • Hoerr, R.A.1    Matthews, D.E.2    Bier, D.M.3    Young, V.R.4
  • 15
    • 0027452577 scopus 로고
    • An isotopic study of the effect of dietary carbohydrate on the metabolic fate of dietary leucine and phenylalanine
    • Krempf M, Hoerr RA, Pelletier VA, Marks LM, Gleason R, Young VR. An isotopic study of the effect of dietary carbohydrate on the metabolic fate of dietary leucine and phenylalanine. Am J Clin Nutr 1993;57:161-9.
    • (1993) Am J Clin Nutr , vol.57 , pp. 161-169
    • Krempf, M.1    Hoerr, R.A.2    Pelletier, V.A.3    Marks, L.M.4    Gleason, R.5    Young, V.R.6
  • 17
    • 0026624926 scopus 로고
    • Leucine and phenylalanine kinetics during mixed meal ingestion: A multiple tracer approach
    • Biolo G, Tessari P, Inchiostro S, et al. Leucine and phenylalanine kinetics during mixed meal ingestion: a multiple tracer approach. Am J Physiol 1992;262:E455-63.
    • (1992) Am J Physiol , vol.262
    • Biolo, G.1    Tessari, P.2    Inchiostro, S.3
  • 18
    • 0027518331 scopus 로고
    • Splanchnic bed utilization of leucine and phenylalanine in humans
    • Matthews DE, Marano MA, Campbell RG. Splanchnic bed utilization of leucine and phenylalanine in humans. Am J Physiol 1993;264: E109-18
    • (1993) Am J Physiol , vol.264
    • Matthews, D.E.1    Marano, M.A.2    Campbell, R.G.3
  • 19
    • 0023016686 scopus 로고
    • Control of phenylalanine and tyrosine metabolism by phosphorylation mechanisms
    • Pogson CI, Dickson AJ, Knowles RG, et al. Control of phenylalanine and tyrosine metabolism by phosphorylation mechanisms. Adv Enzyme Regul 1986;25:309-27.
    • (1986) Adv Enzyme Regul , vol.25 , pp. 309-327
    • Pogson, C.I.1    Dickson, A.J.2    Knowles, R.G.3
  • 23
    • 0028001371 scopus 로고
    • Similar 24 h pattern and rate of carbon dioxide production, by indirect calorimetry versus stable isotope dilution, in healthy adults under standardized metabolic conditions
    • El-Khoury AE, Sánchez M, Fukagawa NK, Gleason RE, Young VR. Similar 24 h pattern and rate of carbon dioxide production, by indirect calorimetry versus stable isotope dilution, in healthy adults under standardized metabolic conditions. J Nutr 1994;124:1615-27.
    • (1994) J Nutr , vol.124 , pp. 1615-1627
    • El-Khoury, A.E.1    Sánchez, M.2    Fukagawa, N.K.3    Gleason, R.E.4    Young, V.R.5
  • 24
    • 0027686728 scopus 로고
    • Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies
    • Vogt JA, Chapman TE, Wagner DA, Young VR, Burke JF. Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies. Biol Mass Spectrom 1993;22:600-12.
    • (1993) Biol Mass Spectrom , vol.22 , pp. 600-612
    • Vogt, J.A.1    Chapman, T.E.2    Wagner, D.A.3    Young, V.R.4    Burke, J.F.5
  • 25
    • 0019974496 scopus 로고
    • 13C]tyrosine in the postabsorptive state
    • 13C]tyrosine in the postabsorptive state. Metabolism 1982;31:999-1005.
    • (1982) Metabolism , vol.31 , pp. 999-1005
    • Clarke, J.T.R.1    Bier, D.M.2
  • 28
    • 0026201807 scopus 로고
    • Whole-body protein and amino acid turnover in man: What can we measure with confidence?
    • Millward DJ, Price GM, Pacy PJH, Halliday D. Whole-body protein and amino acid turnover in man: what can we measure with confidence? Proc Nutr Soc 1991;50:197-216.
    • (1991) Proc Nutr Soc , vol.50 , pp. 197-216
    • Millward, D.J.1    Price, G.M.2    Pacy, P.J.H.3    Halliday, D.4
  • 30
    • 0026558054 scopus 로고
    • VLDL apoprotein B-100, a potential indicator of the isotopic labeling of the hepatic protein synthetic precursor pool in humans: Studies with multiple stable isotopically labeled amino acids
    • Reeds PJ, Hatchey DL, Patterson BW, Motil KJ, Klein PD. VLDL apoprotein B-100, a potential indicator of the isotopic labeling of the hepatic protein synthetic precursor pool in humans: studies with multiple stable isotopically labeled amino acids. J Nutr 1992;122: 457-66.
    • (1992) J Nutr , vol.122 , pp. 457-466
    • Reeds, P.J.1    Hatchey, D.L.2    Patterson, B.W.3    Motil, K.J.4    Klein, P.D.5
  • 31
    • 0006375619 scopus 로고
    • Phenylalanine requirement of women consuming a minimal tyrosine diet and the sparing effect of tyrosine on the phenylalanine requirement
    • Tolbert B, Watts JH. Phenylalanine requirement of women consuming a minimal tyrosine diet and the sparing effect of tyrosine on the phenylalanine requirement. J Nutr 1963;80:111-6.
    • (1963) J Nutr , vol.80 , pp. 111-116
    • Tolbert, B.1    Watts, J.H.2
  • 32
    • 84961008303 scopus 로고
    • The amino acid requirements of man. XIV. The sparing effect of tyrosine on the phenylalanine requirement
    • Rose WC, Wixom RL. The amino acid requirements of man. XIV. The sparing effect of tyrosine on the phenylalanine requirement. J Biol Chem 1955;217:95-101.
    • (1955) J Biol Chem , vol.217 , pp. 95-101
    • Rose, W.C.1    Wixom, R.L.2
  • 33
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1(8476): 307-10.
    • (1986) Lancet , vol.1 , Issue.8476 , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 34
    • 0022989065 scopus 로고
    • Regulation of the activity of hepatic phenylalanine hydroxylase
    • Kaufman S. Regulation of the activity of hepatic phenylalanine hydroxylase. Adv Enzyme Regul 1986;25:37-64.
    • (1986) Adv Enzyme Regul , vol.25 , pp. 37-64
    • Kaufman, S.1
  • 35
    • 0027355636 scopus 로고
    • The phenylalanine hydroxylating system
    • Kaufman S. The phenylalanine hydroxylating system. Adv Enzymol Relat Areas Mol Biol 1993;67:77-264.
    • (1993) Adv Enzymol Relat Areas Mol Biol , vol.67 , pp. 77-264
    • Kaufman, S.1
  • 36
    • 0025719846 scopus 로고
    • Influence of dietary protein intake on whole-body protein turnover in humans
    • Garlick PJ, McNurlan MA, Ballmer PE. Influence of dietary protein intake on whole-body protein turnover in humans. Diabetes Care 1991;14:1189-98.
    • (1991) Diabetes Care , vol.14 , pp. 1189-1198
    • Garlick, P.J.1    McNurlan, M.A.2    Ballmer, P.E.3
  • 37
    • 0024548847 scopus 로고
    • Influence of nutrient intake on protein turnover
    • McNurlan MA, Garlick PJ. Influence of nutrient intake on protein turnover. Diabetes Metab Rev 1989;5:165-89.
    • (1989) Diabetes Metab Rev , vol.5 , pp. 165-189
    • McNurlan, M.A.1    Garlick, P.J.2
  • 38
    • 0023061429 scopus 로고
    • Complexes of sequential metabolic enzymes
    • Srere PA. Complexes of sequential metabolic enzymes. Annu Rev Biochem 1987;56:89-124.
    • (1987) Annu Rev Biochem , vol.56 , pp. 89-124
    • Srere, P.A.1
  • 39
    • 0026436962 scopus 로고
    • Cellular infrastructure and metabolic organization
    • Clegg JS. Cellular infrastructure and metabolic organization. Curr Top Cell Regul 1992;33:3-14.
    • (1992) Curr Top Cell Regul , vol.33 , pp. 3-14
    • Clegg, J.S.1
  • 40
    • 0026436963 scopus 로고
    • Enzyme organization and the direction of metabolic flow: Physiochemical considerations
    • Westerloff HV, Welch GR. Enzyme organization and the direction of metabolic flow: physiochemical considerations. Curr Top Cell Regul 1992;33:361-90.
    • (1992) Curr Top Cell Regul , vol.33 , pp. 361-390
    • Westerloff, H.V.1    Welch, G.R.2
  • 41
    • 0026786546 scopus 로고
    • Phenylalanine and tyrosine kinetics in relation to altered protein and phenylalanine and tyrosine intakes in healthy young men
    • Cortiella J, Marchini JS, Branch S, Chapman TE, Young VR. Phenylalanine and tyrosine kinetics in relation to altered protein and phenylalanine and tyrosine intakes in healthy young men. Am J Clin Nutr 1992;56:517-25.
    • (1992) Am J Clin Nutr , vol.56 , pp. 517-525
    • Cortiella, J.1    Marchini, J.S.2    Branch, S.3    Chapman, T.E.4    Young, V.R.5
  • 42
    • 0028362853 scopus 로고
    • Phenylalanine and tyrosine kinetics for different patterns and indispensable amino acid intakes in adult humans
    • Marchini JS, Cortiella J, Hiramatsu T, Castillo L, Chapman TE, Young VR. Phenylalanine and tyrosine kinetics for different patterns and indispensable amino acid intakes in adult humans. Am J Clin Nutr 1994;60:79-86.
    • (1994) Am J Clin Nutr , vol.60 , pp. 79-86
    • Marchini, J.S.1    Cortiella, J.2    Hiramatsu, T.3    Castillo, L.4    Chapman, T.E.5    Young, V.R.6
  • 45
    • 0025313161 scopus 로고
    • Significant phenylalanine hydroxylation in vivo in patients with classical phenylketonuria
    • Thompson GN, Halliday D. Significant phenylalanine hydroxylation in vivo in patients with classical phenylketonuria. J Clin invest 1990; 86317-22.
    • (1990) J Clin Invest , vol.86 , pp. 317-322
    • Thompson, G.N.1    Halliday, D.2
  • 46
    • 0026801043 scopus 로고
    • Meal stimulation of albumin synthesis is a significant contributor to whole body protein synthesis in humans
    • DeFeo P, Horber FF, Haymond MW. Meal stimulation of albumin synthesis is a significant contributor to whole body protein synthesis in humans. Am J Physiol 1992;263:E794-9.
    • (1992) Am J Physiol , vol.263
    • DeFeo, P.1    Horber, F.F.2    Haymond, M.W.3
  • 47
    • 0019418761 scopus 로고
    • Increased plasma tyrosine concentrations in patients with cirrhosis and fulminant hepatic failure associated with increased plasma tyrosine flux and reduced oxidation capacity
    • O'Keefe SJD, Abraham R, El-Zayadi A, Marshall W, Davis M, Williams R. Increased plasma tyrosine concentrations in patients with cirrhosis and fulminant hepatic failure associated with increased plasma tyrosine flux and reduced oxidation capacity. Gastroenterology 1981;81:1017-24.
    • (1981) Gastroenterology , vol.81 , pp. 1017-1024
    • O'Keefe, S.J.D.1    Abraham, R.2    El-Zayadi, A.3    Marshall, W.4    Davis, M.5    Williams, R.6
  • 48
    • 0023583115 scopus 로고
    • Whole-body leucine, phenylalanine and tyrosine kinetics in end-stage liver disease before and after hepatic transplantation
    • Shanbhogue RLK, Bistrian BR, Lakshman K, et al. Whole-body leucine, phenylalanine and tyrosine kinetics in end-stage liver disease before and after hepatic transplantation. Metabolism 1987;36:1047-53
    • (1987) Metabolism , vol.36 , pp. 1047-1053
    • Shanbhogue, R.L.K.1    Bistrian, B.R.2    Lakshman, K.3
  • 49
    • 0017835818 scopus 로고
    • Abnormalities of phenylalanine and tyrosine kinetics: Significance in septic and non-septic burned patients
    • Herndon DN, Wilmore DW, Mason AD, Pruitt BA, Abnormalities of phenylalanine and tyrosine kinetics: significance in septic and non-septic burned patients. Arch Surg 1978;113:133-5.
    • (1978) Arch Surg , vol.113 , pp. 133-135
    • Herndon, D.N.1    Wilmore, D.W.2    Mason, A.D.3    Pruitt, B.A.4
  • 50
    • 0021045555 scopus 로고
    • Plasma amino acid levels in the first few days after burn injury and their predictive values
    • Cynober L, Dinh FN, Saizy R, Blonde F, Giboudeau J. Plasma amino acid levels in the first few days after burn injury and their predictive values. Intensive Care Med 1983;9:325-31.
    • (1983) Intensive Care Med , vol.9 , pp. 325-331
    • Cynober, L.1    Dinh, F.N.2    Saizy, R.3    Blonde, F.4    Giboudeau, J.5
  • 52
    • 0024564201 scopus 로고
    • Amino acid metabolism in thermal bums
    • Cynober L. Amino acid metabolism in thermal bums. JPEN J Parenter Enteral Nutr 1989;13:196-205.
    • (1989) JPEN J Parenter Enteral Nutr , vol.13 , pp. 196-205
    • Cynober, L.1
  • 53
    • 0026725362 scopus 로고
    • Alterations in levels of plasma phenylalanine and its catabolism in the liver of stressed rats
    • Mori E, Suzuki H, Hasebe M, Kobayashi K. Alterations in levels of plasma phenylalanine and its catabolism in the liver of stressed rats. Metabolism 1992;41:807-13.
    • (1992) Metabolism , vol.41 , pp. 807-813
    • Mori, E.1    Suzuki, H.2    Hasebe, M.3    Kobayashi, K.4
  • 54
    • 0023483376 scopus 로고
    • Newer concepts of the indispensable amino acids
    • Laidlaw SA, Kopple JD. Newer concepts of the indispensable amino acids. Am J Clin Nutr 1987;46:593-605.
    • (1987) Am J Clin Nutr , vol.46 , pp. 593-605
    • Laidlaw, S.A.1    Kopple, J.D.2
  • 55
    • 0001979878 scopus 로고
    • The notion of the nutritional essentiality of amino acids, revisited, with a note on the indispensable amino acid requirements in adults
    • Cynober L, ed. Boca Raton, FL: CRC Press
    • Young VR, El-Khoury AE. The notion of the nutritional essentiality of amino acids, revisited, with a note on the indispensable amino acid requirements in adults. In: Cynober L, ed. Amino acid metabolism and therapy in health and nutritional disease. Boca Raton, FL: CRC Press, 1995:191-232.
    • (1995) Amino Acid Metabolism and Therapy in Health and Nutritional Disease , pp. 191-232
    • Young, V.R.1    El-Khoury, A.E.2
  • 56
    • 0029005749 scopus 로고
    • Phenylalanine hydroxylase activity in preterm infants: Is tyrosine a conditionally essential amino acid?
    • Kilani RA, Cole FS, Bier DM. Phenylalanine hydroxylase activity in preterm infants: is tyrosine a conditionally essential amino acid? Am J Clin Nutr 1995;61:1218-23.
    • (1995) Am J Clin Nutr , vol.61 , pp. 1218-1223
    • Kilani, R.A.1    Cole, F.S.2    Bier, D.M.3


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