The effect of ibogaine on sigma- and NMDA-receptor-mediated release of [3H]dopamine

Brain Research Bulletin

Volumn 40, Issue 1, 1996, Pages 63-67

  Sershen, Henry ^a   Hashim, Audrey ^a   Lajtha, Abel ^a  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

( ) Pentazocine; Dopamine release; Ibogaine; MK 801; NMDA receptor; Sigma receptor; Striatum (Mouse)

Indexed keywords

COCAINE; DIZOCILPINE; DOPAMINE; IBOGAINE; INDOLE ALKALOID; KAPPA OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OPIATE AGONIST; PENTAZOCINE; SIGMA OPIATE RECEPTOR; SPIRADOLINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC SYSTEM; DRUG DEPENDENCE; DRUG EFFECT; DRUG MECHANISM; MALE; MOUSE; NEUROMODULATION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029877521     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/0361-9230(96)00039-1     Document Type: Article

References (28)

1. Berkowitz, B. A. Effects of the optical isomers of the narcotic antagonist analgesic pentazocine on brain and heart biogenic amines. Eur. J. Pharmacol. 26:359-365; 1974.
2. Caudle, R. M.; Chavkin, C.; Dubner, R. Kappa 2 opioid receptors inhibit NMDA receptor-mediated synaptic currents in guinea pig CA3 pyramidal cells. J. Neurosci. 14:5580-5590; 1994.
3. Codd, E. E. High affinity ibogaine binding to a mu opioid agonist site. Life Sci. 57:315-320; 1995.
4. Deecher, D. C.; Teitler, M.; Soderland, D. M.; Bommann, W. G.; Kuehne, M. E.; Glick, S. D. Mechanisms of action of ibogaine and harmaline congeners based on radioligand binding studies. Brain Res. 571:242-247; 1992.
5. Gershon, S.; Lang, W. J. A psycho-pharmacological study of some indole alkaloids. Arch. Int. Pharmacodyn. 135:31-56; 1962.
6. Goldstein, S. R.; Matsumoto, R. R.; Thompson, T. L.; Patrick, R. L.; Bowen, W. D.; Walker, J. M. Motor effects of two sigma ligands mediated by nigrostriatal dopamine neurons. Synapse 4:254-258; 1989.
7. 3H] dopamine release from rat striatal slices by sigma receptor ligands. J. Pharmacol. Exp. Ther. 271:212-219; 1994.
8. Harsing, L. G. Jr.; Sershen, H.; Lajtha, A. Evidence that ibogaine releases dopamine from the cytoplasmic pool in isolated mouse striatum. J. Neural Transm. 96:215-225; 1994.
9. Izenwasser, S.; Newman, A. H.; Katz, J. L. Cocaine and several sigma receptor ligands inhibit dopamine uptake in rat caudate-putamen. Eur. J. Pharmacol. 243:201-205; 1993.
10. Jackisch, R.; Hotz, H.; Hertting, G. No evidence for pesynaptic opioid receptors on cholinergic, but presence of κ-receptors on dopaminergic neurons in the rabbit caudate nucleus: Involvement of endogenous opioids. Naunyn-Schmiedeberg's Arch. Pharmacol. 348:234-241; 1993.
11. 2 receptors. Life Sci. 57:57-62; 1995.
12. Maisonneuve, L. M.; Keller, R. W. Jr.; Glick, S. D. Interactions between ibogaine, a potential anti-addictive agent, and morphine: an in vivo microdialysis study. Eur. J. Pharmacol. 199:35-42; 1991.
13. Monnet, F. P.; Debonnel, G.; Junien, J. L.; De Montigny, C. N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors. Eur. J. Pharmacol. 179:441-445; 1990.
14. Mulder, A. H.; Wardeh, G.; Hogenboom, F.; Frankhuyzen, A. L. κ-δ-Opioid receptor agonists differentially inhibit striatal dopamine and acetylcholine release. Nature 308:278-280; 1984.
15. Pearl, S. M.; Herrick-Davis, K.; Teitler, M.; Glick, S. D. Radioligand-binding study of noribogaine, a likely metabolite of ibogaine. Brain Res. 675:342-344; 1995.
16. 3H]MK-801 binding to the NMDA receptor complex. Psychopharmacology 114:672-674; 1994.
17. Popik, P.; Layer, R. T.; Skolnick, P. 100 years of ibogaine: Neurochemical and pharmacological actions of a putative anti-addictive drug. Pharmacol. Rev. 47:235-253; 1995.
18. Raymond-Hamet; Rothlin, E. Action of some sympathostenic alkaloids on cholinesterase. C.R. Soc. Biol. 150:1384-1386; 1956.
19. Ronken, E.; Van Muiswinkel, F. L.; Mulder, A. H.; Schoffelmeer, A. N. Opioid receptor-mediated inhibition of evoked catecholamine release from cultured neurons of rat ventral mesencephalon and locus coeruleus. Eur. J. Pharmacol. 230:349-355; 1993.
20. Sershen, H.; Hashim, A.; Lajtha, A. Effect of ibogaine on serotonergic and dopaminergic interactions in striatum from mice and rats. Neurochem. Res. 19:1463-1466; 1994.
21. Sershen, H; Harsing, L. G. Jr.; Lajtha, A. Ibogaine reduces preference for cocaine consumption in C57BL/6By mice. Pharmacol. Biochem. Behav. 47:13-19; 1994.
22. Sershen, H; Harsing, L. G. Jr.; Hashim, A.; Lajtha, A. Ibogaine reduces amphetamine-induced locomotor stimulation in C57BL/6By mice, but stimulates locomotor activity in rats. Life Sci. 51:1003-1011; 1992.
23. Sershen, H; Hashim, A.; Harsing, L. G. Jr.; Lajtha, A. Ibogaine antagonizes cocaine-induced locomotor stimulation in mice. Life Sci. 50:1079-1086; 1992.
24. 3H] serotonin from mouse striatum. Pharmacol. Biochem. Behav. (in press).
25. Sershen, H; Hashim, A.; Lajtha, A. The effect of ibogaine on kappa-opioid- and 5-HT3-induced changes in stimulation-evoked dopamine release in vitro from striatum of C57BL/6By mice. Brain Res. Bull. 36:587-591; 1995.
26. Sloviter, R. S.; Drust, E. G.; Damino, B. P.; Connor, J. D. A common mechanism for lysergic acid, indoealkylamine and phenethylamine hallucinogens: Serotonergic mediation of behavioral effects in rats. J. Pharmacol. Exp. Ther. 214:231-238; 1980.
27. Walker, J. M.; Bowen, W. D.; Walker, F. O.; Matsumoto, R. R.; De Costa, B.; Rice, K. C. Sigma receptors: Biology and function. Pharmacol. Rev. 42:355-402; 1990.
28. Wise, R. A.; Bozarth, M. A. Action of drugs of abuse on brain reward systems: An update with specific attention to opiates. Pharmacol. Biochem. Behav. 17:239-243; 1982.