Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity receptors

Journal of Neurochemistry

Volumn 66, Issue 4, 1996, Pages 1391-1399

  Robledo, Olivier ^a   Auguste, Patrick ^a   Coupey, Lionel ^b   Praloran, Vincent ^b   Chevalier, Sylvie ^a   Pouplard, Annick ^a   Gascan, Hugues ^a  

^a ANGERS UNIVERSITY HOSPITAL   (France)

^b LIMOGES UNIVERSITY HOSPITAL   (France)

Author keywords

Binding interactions; Ciliary neurotrophic factor; Cytokine receptors; Leukemia inhibitory factor

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; COMPLEMENTARY DNA; CYTOKINE RECEPTOR; INTERLEUKIN 6; IODINE 125; LEUKEMIA INHIBITORY FACTOR; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

EID: 0029877337     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66041391.x     Document Type: Article

References (44)

1. Baumann H., Ziegler S. F., Mosley B., Morella K. K., Pajovic S., and Gearing D. P. (1993) Reconstitution of the response to leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in hepatoma cells. J. Biol. Chem. 268, 8414-8417.
2. Bazan J. F. (1989) A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain. Biochem. Biophys. Res. Commun. 164, 788-795.
3. Bazan J. F. (1991) Neuropoietic cytokines in the hematopoietic fold. Neuron 7, 197-208.
4. Biedler J. L., Helron L., and Spengler B. A. (1973) Morphology and growth, tumorigenicity and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res. 33, 2643-2649.
5. Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chlorophorm extraction. Anal. Biochem. 162, 156-159.
6. Conover J. C., Ip N. Y., Poueymirou W. T., Bates B., Goldfarb M. P., DeChiara T. M., and Yancopoulos G. D. (1993) Ciliary neurotrophic factor maintains the pluripotentiality of embryonic stem cells. Development 119, 559-565.
7. Coupey L., Berrada L., Gascan H., Godard A., and Praloran V. (1993) High titer anticytokine antibodies obtained by intralymphnode immunization with low amounts of antigen. Cytokine 5, 564-569.
8. Davis S., Aldrich T. H., Valenzuela D. M., Wong V. V., Furth M. E., Squinto S. P., and Yancopoulos G. D. (1991) The receptor for ciliary neurotrophic factor. Science 253, 59-63.
9. Davis S., Aldrich T. H., Ip N. Y., Stahl N., Scherer S., Farrugella T., DiStefano P. S., Curtis R., Panayotatos N., Gascan H., Chevalier S., and Yancopoulos G. D. (1993a) Released form of CNTF receptor α component as a soluble mediator of CNTF responses. Science 259, 1736-1739.
10. Davis S., Aldrich T. H., Stahl N., Pan L., Taga T., Kishimoto T., Ip N. Y., and Yancopoulos G. D. (1993b) LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260, 1805-1808.
11. Fourcin M., Chevalier S., Lebrun J. J., Kelly P., Pouplard A., Wijdenes J., and Gascan H. (1994) Involvement of gp130/ interleukin-6 receptor transducing component in interleukin-11 receptor. Eur. J. Immunol. 24, 277-280.
12. Gascan H., Godard A., Ferenz C., Naulet J., Praloran V., Peyrat M. A., Hewick R., Jacques Y., Moreau J. F., and Soulillou J. P. (1989) Characterization and NH2-terminal amino acid sequence of natural human interleukin for DA cells: leukemia inhibitory factor. Differentiation inhibitory activity secreted by a T lymphoma cell line. J. Biol. Chem. 264, 21509-21515.
13. Gearing D. P. and Bruce A. G. (1992) Oncostatin M binds the high-affinity leukemia inhibitory factor receptor. New Biol. 4, 61-65.
14. Gearing D. P., Thut C. J., VandenBos T., Gimpel S. D., Delaney P. B., King J , Price V., Cosman D., and Beckmann M. P. (1991) Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J. 10, 2839-2848.
15. Gearing D. P., Comeau M. R., Friend D. J., Gimpel S. D., Thut C. J., McGourty J., Brasher K. K., King J. A., Gillis S., Mosley B., Ziegler S. F., and Cosman D. (1992) The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor. Science 255, 1434-1437.
16. Gearing D. P., Ziegler S. F., Coneau M. R., Friend D., Thoma B., Cosman D., Park L., and Mosley B. (1994) Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor. Proc. Natl. Acad. Sci. USA 91, 1119-1123.
17. Gough N. M., Gearing D. P., King J. A., Willson T. A., Hilton D. J., Nicola N. A., and Metcalf D. (1988) Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor. Proc. Natl. Acad. Sci. USA 85, 2623-2627.
18. Guillet C., Fourcin M., Chevalier S., Pouplard A., and Gascan H. (1995) ELISA detection of circulating levels of LIF, OSM and CNTF in septic shocks. Ann. NY Acad. Sci. 762, 407-409.
19. Hilton D. J., Hilton A. A., Raicevic A., Rakar S., Smith M. H., Gough N. M., Begley C. G., Metcalf D., Nicola N. A., and Willson T. A. (1994) Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction. EMBO J. 13, 465-475.
20. Idzerda R. L., March C. J., Mosley B., Lyman S. D., Vanden Bos T., Gimpel S. D., Din W. S., Grabstein K. H., Widmer M. B., Park L. S., Cosman D., and Beckmann P. M. (1990) Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J. Exp. Med. 171, 861-873.
21. Ip N. Y., Nye S. H., Boulton T. G., Davis S., Taga T., Li Y., Birren S. J., Yasukawa K , Kishimoto T., Anderson D. J., Stahl N., and Yancopoulos G. D. (1992) CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69, 1121-1132.
22. Kishimoto T., Akira S., and Taga T. (1992) Interleukin-6 and its receptor: a paradigm for cytokines. Science 258, 593-597.
23. Layton M. J., Cross B. A., Metcalf D., Ward L. D., Simpson R. D., and Nicola N. A. (1992) A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor. Proc. Natl. Acad. Sci. USA 89, 8616-8620.
24. Leary A. G., Wong G. G., Clark S. C., Smith A. G., and Ogawa M. (1990) Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells. Blood 75, 1960-1964.
25. Lin L. F., Mismer D., Lile J. D., Armes L. G., Butler E. T., Vannice J. L., and Collins F. (1989) Purification, cloning, and expression of ciliary neurotrophic factor (CNTF). Science 246, 1023-1025.
26. Moreau J F., Donaldson D. D., Bennett F., Witek Giannotti J., Clark S. C., and Wong G. G. (1988) Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells. Nature 336, 690-692.
27. Murakami M., Hibi M., Nakagawa N., Nakagawa T., Yasukawa K , Yamanishi K., Taga T., and Kishimoto T. (1993) IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science 260, 1808-1810.
28. Musashi M., Clark S. C., Sudo T., Urdal D. L., and Ogawa M (1991) Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice. Blood 78, 1448-1451.
29. Noguchi M., Nakamura Y , Russell S. M., Ziegler S. F., Tsang M., Cao X., and Leonard W. J. (1993) Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science 262, 1877-1880.
30. Paul S. R., Bennett F., Calvetti J. A., Kelleher K., Wood C. R., O'Hara R. M., Leary A. C., Sibley B., Clark S. C., and Williams D. A. (1990) Molecular cloning of a cDNA encoding interleukin 11, a stromal cell derivated lymphopoietic and hematopoietic cytokine. Proc. Natl. Acad. Sci. USA 87, 7512-7516.
31. Rose T. M. and Bruce A. G. (1991) Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin. Proc. Natl. Acad. Sci. USA 88, 8641-8645.
32. Smith A. G., Heath J. K., Donaldson D. D., Wong G. G., Moreau J., Stahl M., and Rogers D. (1988) Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336, 688-690.
33. Stahl N., Davis S., Wong V., Taga T., Kishimoto T., Ip N. Y., and Yancopoulos G. D. (1993) Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component. J. Biol. Chem. 268, 7628-7631.
34. Stockli K. A., Lottspeich F., Sendtner M., Masiakowski P., Carroll P., Gotz R., Lindholm D., and Thoenen H. (1989) Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature 342, 920-923.
35. Taga T., Hibi M., Hirata Y., Yamasaki K., Yasukawa K., Matsuda T., Hirano T., and Kishimoto T. (1989) Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell 58, 573-581.
36. Takahashi R., Yokoji H., Hayashi M., Hu J., and Deguchi T. (1994) A null mutation in the human CNTF gene is not causally related to neurological diseases. Nature Genet. 7, 79-84.
37. Takebe Y., Seiki M., Fujisawa J. I., Hoy P., Yokota T., Arai K. I., Yoshida M., and Arai N. (1988) SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 8, 466-472.
38. Tejedor F. and Ballesta J. P. (1982) Iodination of biological samples without loss of functional activity. Anal. Biochem. 127, 143-149.
39. Thoma B., Bird T. A., Friend D. J., Gearing D. P., and Dower S. K. (1994) Oncostatin M and leukemia inhibitory factor trigger overlapping and different signals through partially shared receptor complexes. J Biol. Chem. 269, 6215-6222.
40. Wong V., Pearsall D., Arriaga R., Ip N. Y., Stahl N., and Lindsay R. M. (1995) Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines. J. Biol. Chem. 270, 313-318.
41. Yamamori T., Fukada K., Aebersold R., Korsching S., Fann M. J., and Patterson P. H. (1989) The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor. Science 246, 1412-1416.
42. Yamasaki K., Taga T., Hirato H., Kawanishi Y., Seed B., Taniguchi T., Hirano T., and Kishimoto T. (1988) Cloning and expression of the human interleukin-6 (BSF-2/IFNβ 2) receptor. Science 241, 825-828.
43. Yin T. G., Schendel P., and Yang Y. C. (1992) Enhancement of in vitro and in vivo antigen-specific antibody responses by interleukin-11. J. Exp. Med. 175, 211-216.
44. Yin T., Taga T., Tsang M L., Yasukawa K., Kishimoto T., and Yang Y. C. (1993) Involvement of IL-6 signal transducer gp130 in IL-11 mediated signal transduction. J. Immunol. 151, 2555-2561.