High-altitude pulmonary edema: Current concepts

Annual Review of Medicine

Volumn 47, Issue , 1996, Pages 267-284

  Hultgren, Herbert N ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

High elevations lung; Hypoxia lung in; Hypoxic vasoconstriction; Mountain illness HAPE

Indexed keywords

NIFEDIPINE;

ADULT; AIRWAY; ALTITUDE; ALTITUDE ACCLIMATIZATION; ALTITUDE DISEASE; ANIMAL TISSUE; ARTERY RESISTANCE; BLOOD VESSEL INJURY; CAPILLARY; CLIMBING; COUGHING; CYANOSIS; DISEASE SEVERITY; DOG; DYSPNEA; EMERGENCY TREATMENT; ERYTHROCYTE; FEMALE; FORWARD HEART FAILURE; GENERAL AND MISCELLANEOUS PROCEDURES AND TECHNIQUES; HEART LEFT VENTRICLE FILLING PRESSURE; HUMAN; HYPOXIC LUNG VASOCONSTRICTION; LUNG ALVEOLUS; LUNG ARTERY PRESSURE; LUNG EDEMA; LUNG WEDGE PRESSURE; MALE; MORTALITY; MUSCLE WEAKNESS; NONHUMAN; OXYGEN THERAPY; PRIORITY JOURNAL; PROTEIN DEPLETION; REVIEW; SKIING; TACHYCARDIA; TACHYPNEA;

ACCLIMATIZATION; ALTITUDE SICKNESS; ANIMALS; CALCIUM CHANNEL BLOCKERS; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; DOGS; HUMANS; NIFEDIPINE; OXYGEN INHALATION THERAPY; PULMONARY EDEMA; PULMONARY WEDGE PRESSURE; VASCULAR RESISTANCE; VENTRICULAR FUNCTION, LEFT;

EID: 0029876975     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.47.1.267     Document Type: Review

References (71)

1. Ravenhill T. 1913. Some experiences of mountain sickness in the Andes. J. Trop. Med. Hyg. 20:313-20
2. Crane H. 1927. Soroche. Mountain sickness anoxemia. Anal. Fac. Med. 2:306-12
3. Lizarraga L. 1955. Soroche agudo: edema agudo de pulmón. An. Facul. Med. 38(2): 244
4. Bardales A. 1957. Edema pulmonar agudo por soroche grave. Rev. Peruana Cardiol. 6(2):115
5. Alzamora-Castro, Garrido-Lecca G, Battilan G. 1961. Pulmonary edema of high altitude. Am. J. Cardiol. 7:769-78
6. Vega B. 1956. Edema of the lung in mountain sickness. JAMA 160:698 (For. Lett.)
7. Hultgren H, Spickard W. 1960. Medical experiences in Peru. Stanford Med. Bull. 18:76-95
8. Houston C. 1960. Acute pulmonary edema of high altitude. N. Engl. J. Med. 263: 478-80
9. Hultgren H, Spickard W, Hellriegel K, Houston C. 1961. High altitude pulmonary edema. Medicine 40:289-313
10. Singh I, Kapila C, Khanna P, et al. 1965. High altitude pulmonary edema. Lancet 30: 229-34
11. Menon N. 1965. High altitude pulmonary edema. N. Engl. J. Med. 273:66-74
12. Hultgren H, Honigman B, Theis K, Nicholas D. 1995. High altitude pulmonary edema in a ski resort. West. J. Med. In press
13. Hultgren H. 1978. High altitude pulmonary edema. In Water and Solute Exchange, ed. N Staub, pp. 437-64. New York: Marcel Dekker
14. Kobayashi T, Koyama S, Lubo K, et al. 1987. Clinical features of patients with high altitude pulmonary edema in Japan. Chest 92:814-21
15. Vock P, Fretz C, Franciolli M, et al. 1989. High altitude pulmonary edema: findings at high altitude chest radiography and physical examination. Radiology 170:661-66
16. Vock P, Fischer H, Bärtsch P. 1993. Radiomorphology of high altitude pulmonary edema: new views. In Hypoxia and Molecular Medicine, ed. J Sutton, G Coates, C Houston, pp. 259-64. Burlington, VT: Queen City Printers
17. Vock P, Brutsche M, Nanzer A, Bärtsch P. 1991. Variable radiomorphologic data of high altitude pulmonary edema. Chest 100: 1306-11
18. Fleischner F. 1967. The butterfly pattern of acute pulmonary edema. Am. J. Cardiol. 20:46-50
19. Hackett P, Oelz O. 1992. The Lake Louise Consensus of the definition and quantification of altitude illness. In Hypoxia and Mountain Medicine, ed. J Sutton, G Coates, C Houston, pp. 327-30. Burlington, VT: Queen City Printers
20. Bärtsch P, Muller A, Hofstetter D, et al. 1993. AMS and HAPE scoring in the Alps. See Ref. 16, pp. 265-71
21. Hultgren H, Marticorena E. 1978. High altitude pulmonary edema: epidemiologic observations in Peru. Chest 74:372-76
22. Hultgren H, Lopez C, Lundberg E, Miller H. 1964. Physiologic studies of pulmonary edema at high altitude. Circulation 29: 393-408
23. Fasules J, Wiggins J, Wolfe R. 1985. Increased lung vasoreactivity in children from Leadville, Colorado, after recovery from high altitude pulmonary edema. Circulation 72:957-62
24. Yagi H, Yamada H, Kobayashi T, Sekiguchi M. 1990. Doppler assessment of pulmonary hypertension induced by hypoxic breathing in subjects susceptible to high altitude pulmonary edema. Am. Rev. Respir. Dis. 142;796-801
25. Hultgren H. 1982. Pulmonary hypertension and pulmonary edema. In Oxygen Transport to Human Tissues, ed. J Loeppky, M Riedesel. New York: Elsevier Biomedical
26. Hultgren H, Grover R, Hartley L. 1971. Abnormal circulatory responses to high altitude in subjects with a previous history of high altitude pulmonary edema. Circulation 44:759-70
27. Hackett P, Creagh C, Grover R, et al. 1980. High altitude pulmonary edema in persons without the right pulmonary artery. N. Engl. J. Med. 302:1070-73
28. Rios B, Driscoll D, McNamara D. 1985. Pulmonary edema with absent right pulmonary artery. Pediatrics 75:314-17
29. Hochstrasser J, Nazer A, Oelz C. 1986. Altitude edema in the Swiss Alps: observations on the incidence and clinical course in 50 patients. Schweiz. Med. Wochenschr. 116:866-73
30. Maggiorini M, Buhler M, Waiter M, Oelz O. 1990. Prevalence of acute mountain sickness in the Swiss Alps. Br. Med. J. 301:853-55
31. Hackett P, Rennie D. 1976. The incidence, importance, and prophylaxis of acute mountain sickness. Lancet 2:1149-54
32. Singh I, Khanna P, Srivastava M, et al. 1969. Acute mountain sickness. N. Engl. J. Med. 280:175-84
33. Lobenhoffer H, Zink R, Brendel W. 1982. High altitude pulmonary edema: analysis of 166 cases. In High Altitude Physiology and Medicine, ed. W Brendel, R Kink. New York: Springer Verlag
34. Sophocles A. 1986. High altitude pulmonary edema in Vail, Colorado. West. J. Med. 144:569-73
35. Lopez C. 1971. Edema agudo pulmónar de altura in nimos. Doctoral thesis. Univ. Pervana Cayetano Heridia, Lima, Peru. 45 pp.
36. Scoggin C, Hyers T, Reeves J, Grover R. 1977. High altitude pulmonary edema in the children and young adults of Leadville, Colorado. N. Engl. J. Med. 297:1269-72
37. Antezana G, Leguia G, Guzman A, et al. 1982. Hemodynamic study of high altitude pulmonary edema (12,200 ft). See Ref. 33, pp. 232-41
38. Penaloza D, Sime D. 1969. Circulatory dynamics during high altitude pulmonary edema. Am. J. Cardiol. 23:369-78
39. Fred H, Schmidt A, Bates T, Hecht H. 1962. Acute pulmonary edema of high altitude: clinical and physiologic observations. Circulation 25:929-37
40. Fukushima M, Yochimura K, Kubol K, et al. 1980. A case of high altitude pulmonary edema. Jpn. J. Thorac. Dis. 18:753-57
41. Hultgren H, Lopez C, Lundberg E, Miller H. 1964. Physiologic studies of pulmonary edema at high altitude. Circulation 29: 393-408
42. Hultgren H, Spickard W, Lopez D. 1962. Further studies of high altitude pulmonary edema. Br. Heart J. 24:95-102
43. Arias-Stella J, Kruger H. 1963. Pathology of high altitude pulmonary edema. Arch. Pathol. 76:147-57
44. Nayak N, Roy S, Narayana T. 1964. Pathologic features of altitude sickness. Am. J. Pathol. 45:381-91
45. Dawson C, Bronikowski T, Linehan J, Hakim T. 1983. Hypoxic vasoconstriction can increase intra-regional perfusion heterogeneity at a given perfusion level. J. Appl. Physiol. 54:654-60
46. Fowler K, Read J. 1963. 1963. Effect of alveolar hypoxia on zonal distribution of pulmonary blood flow. J. Appl. Physiol. 18:244-50
47. Lehr D, Triller M, Fisher L, et al. 1963. Induced changes in the pattern of pulmonary blood flow in the rabbit. Circ. Res. 13:119-31
48. Hyman A. 1961. Effects of large increases in pulmonary blood flow on pulmonary venous pressure. J. Appl. Physiol. 217: 1177-78
49. Welling K, Sanchez R, Raun J, et al. 1993. Effect of prolonged alveolar hypoxia on pulmonary arterial pressure and segmental vascular resistance. J. Appl. Physiol. 75: 1194-200
50. Combret M, Rouby J, Smiegan J, et al. 1987. Pulmonary edema during pulmonary embolism. Br. J. Dis. Chest 81:407-14
51. Arnold L, Keane J, Kan J, et al. 1988. Transient unilateral pulmonary edema after successful balloon dilatation of peripheral pulmonary artery stenosis. Am. J. Cardiol. 62:327-30
52. Moser K, Daily P, Peterson K, et al. 1987. Thromboendarterectomy for chronic, major-vessel thromboembolic pulmonary hypertension: immediate and long-term results in 42 patients. Ann. Intern. Med. 107: 560-65
53. Levinson R, Shure D, Moser K. 1986. Reperfusion pulmonary edema after pulmonary artery thromboendarterectomy. Am. Rev. Respir. Dis. 139:1291-45
54. Pool P, Vogel J, Blount G Jr. 1962. Congenital unilateral absence of a pulmonary artery. Am. J. Cardiol. 10:706-32
55. Landolt C, Matthay M, Albertine R, et al. 1983. Overperfusion, hypoxia, and increased pressure cause only hydrostatic pulmonary edema in anesthetized sheep. Circ. Res. 52:335-41
56. Schoene R, Swenson E, Pizzo C, et al. 1988. The lung at high altitude: bronchoalvolar lavage in acute mountain sickness and pulmonary edema. J. Appl. Physiol. 64:2605-13
57. West J, Tsukimoto K, Mathieu-Costello O, Prediletto R. 1991. Stress failure in pulmonary capillaries. J. Appl. Physiol. 70: 1731-42
58. Tsukimoto K, Yoshimure N, Ichioka M, et al. 1994. Protein, cell and LTB concentrations of lung edema fluid produced by high capillary pressures in rabbit. J. Appl. Physiol. 76:321-27
59. Vriem C, Snashall P, Staub N. 1976. Protein composition of lung fluids in anesthetized dogs with acute cardiogenic edema. Am. J. Physiol. 231:1466-69
60. Marticorena E, Hultgren H. 1979. Evaluation of therapeutic methods in high altitude pulmonary edema. Am. J. Cardiol. 43:307-12
61. Taber R. 1990. Protocols for the use of a portable hyperbaric chamber for the treatment of high altitude disorders. J. Wilderness Med. 1:181-92
62. King S, Greenlee R. 1990. Successful use of the Gamow hyperbaric bag in the treatment of altitude illness at Mount Everest. See Ref. 61. pp. 193-202
63. Kasic J, Yaron M, Nicholas R, et al. 1991. Treatment of acute mountain sickness: hyperbaric versus oxygen therapy. Ann. Emerg. Med. 20:1109-12
64. Hackett P, Greene E, Roach P, et al. 1990. Nifedipine and hydralazine for treatment of high altitude pulmonary edema. In Hypoxia: The Adaptations, ed. J Sutton, G Coates, J Remmers, p. 219. Philadelphia: B.C. Decker (Abstr.)
65. Oelz O, Maggiorini M, Ritter M, et al. 1989. Nifedipine for high altitude pulmonary edema. Lancet 2:1241-44
66. Bärtsch P, Maggiorini M, Ritter M, et al. 1991. Prevention of high altitude pulmonary edema by nifedipine. N. Engl. J. Med. 325:1284-89
67. McMurty I, Davidson A, Reeves J, Grover R. 1976. Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs. Circ. Res. 38:99-104
68. Bates T. 1972. Pulmonary edema of mountains. Br. Med. J. 3:829 (Lett.)
69. Levine B, Yoshimura K, Kobayashi T, et al. 1989. Dexamethasone in the treatment of acute mountain sickness. N. Engl. J. Med. 321:1707-13
70. Gray G, Bryan A, Frayser R, et al. 1971. Control of acute mountain sickness. Aero. Med. 42:81-84
71. Smith L. 1977. High altitude illness. JAMA 237:1199 (Lett.)