Control of hepatic carbohydrate metabolism and haemodynamics in perfused rat liver by arterial and portal angiotensin II

European Journal of Gastroenterology and Hepatology

Volumn 8, Issue 3, 1996, Pages 279-286

  Reisenleiter, Frank ^a   Katz, Norbert ^a   Gardemann, Andreas ^a,b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Angiotensin II; AT1 receptor; Hepatic artery; Losartan; Perfusion; Portal vein

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; GLUCOSE; LACTIC ACID; LOSARTAN;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; CARBOHYDRATE METABOLISM; HEMODYNAMICS; LIVER METABOLISM; LIVER PERFUSION; METABOLIC REGULATION; NONHUMAN; PORTAL VEIN BLOOD; PRIORITY JOURNAL; RAT;

EID: 0029876550     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199603000-00017     Document Type: Article

References (39)

1. Ferrario CM: The renin-angiotensin system: importance in physiology and pathology. J Cardiovasc Pharmacol 1990, 15 (Suppl 3):S1-S5.
2. Dzau VJ, Pratt RE: Renin-angiotensin system: biology, physiology and pharmacology. In The Heart and Cardiovascular System. New York: Raven Press; 1986:1631-1662.
3. Campbell DC: Tissue renin-angiotensin system: sites of angiotensin formation. J Cardiovasc Pharmacol 1987, 10 (Suppl 7):S1-S8.
4. Campbell DC: Circulating and tissue angiotensin systems. J Clin Invest 1987, 79:1-6.
5. Phillips MI, Speakman EA, Kimura B: Levels of angiotensin and molecular biology of the tissue renin angiotensin systems. Regul Pept 1993, 43:1-20.
6. Phillips MI, Speakman EA, Kimura B: Tissue renin-angiotensin systems. In Cellular and Molecular Biology of the Renin-Angiotensin System. Edited by Raigada MK, Phillips MI, Sumnert C. Boca Raton, Florida: CRC Press; 1993.
7. Dzau VJ: Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses. J Hypertens 1989, 7:933-936.
8. Cassis LA, Lynch KR, Peach MJ: Localization of angiotensinogen mRNA in rat aorta. Circ Res 1988, 62:1259-1262.
9. Greenway CV, Lautt WW: Effects of infusions of catecholamines, angiotensin, vasopressin and histamine on hepatic blood volume in the anaesthetized cat. Br J Pharmacol 1972, 44:177-184.
10. Cohen MM, Sitar DS, McNeill R, Greenway V: Vasopressin and angiotensin on resistance vessels of spleen, intestine, and liver. Am J Physiol 1970, 218:1704-1706.
11. Kelly KA, Nyhus LM: Angiotensin and the liver. Am J Physiol 1966, 210:305-311.
12. Richardson PDI, Withrington PG: The effects of intraportal injections of noradrenaline, adrenaline, vasopressin and angiotensin on the hepatic portal vascular bed of the dog: marked tachyphylaxis to angiotensin. Br J Pharmacol 1977, 59:293-301.
13. Richardson PDI, Withrington PG: The inhibition by glucagon of the vasoconstrictor actions of noradrenaline, angiotensin and vasopressin on the hepatic arterial vascular bed of the dog. Br J Pharmacol 1976, 57:93-102.
14. Ma GY, Cove CD, Hems DA: Inhibition of fatty acid synthesis and stimulation of glucose release by angiotensin II and adrenaline in the perfused mouse liver. Biochem Soc Trans 1977, 5:986-988.
15. Ma GY, Gove CD, Cawthorn MA, Hems DA: Catabolic effects of adrenaline and angiotensin II in the perfused liver of normal and genetically obese (ob/ob) mice. Clin Sci 1979, 56:493-499.
16. Whitton PD, Rodrigues LM, Hems DA: Stimulation by vasopressin, angiotensin and oxytocin of gluconeogenesis in hepatocyte suspension. Biochem J 1978, 176:893-898.
17. Hems DA, Rodrigues LM, Whitton PD: Glycogen phosphorylase, glucose output and vasoconstriction in the perfused rat liver. Biochem J 1976, 160:367-374.
18. Hems DA, Rodrigues LM, Whitton PD: Rapid stimulation by vasopressin, oxytocin and angiotensin II of glycogen degradation in hepatocyte suspensions. Biochem J 1978, 172:311-317.
19. Keppens S, De Wulf H: The activation of glycogen phosphorylase by angiotensin II. FEBS Lett 1976, 68:279-282.
20. DeGasparo M, Whitebread S, Mele M, Motani AS, Whitcombe PJ, Ramjoue HP, et al.: Biochemical characterization of two angiotensin II receptor subtypes in the rat. J Cardiovasc Pharmacol 1990, 16 (Suppl 4):S31-S35.
21. Dudley DTRL, Panek RL, Major TC, Lu GH, Bruns RF, Klinkefus BA, et al.: Subclasses of angiotensin II binding sites and their functional significance. Mol Pharmacol 1990, 38:170-377.
22. Chin AT: DuP 753: a second generation of nonpeptide angiotensin II receptor antagonists. Biochem Biophys Res Commun 1991, 177:209-217.
23. Gardemann A, Strulik H, Jungermann K: A portal-arterial glucose concentration gradient as a signal for an insulin-dependent net glucose uptake in perfused rat liver. FEBS Lett 1986, 202:255-259.
24. Gardemann A, Jahns U, Jungermann K: Control of glycogenolysis and blood flow by arterial and portal norepinephrine in perfused liver. Am J Physiol 1991, 260:E762-E771.
25. Meyerholz HH, Gardemann A, Jungermann K: Control of glycogenolysis and blood flow by arterial and portal adrenaline in perfused liver. Biocnem J 1991, 275:609-616.
26. Miura H, Jungermann K, Gardemann A: Differential control by arterial and portal noradrenaline of hepatic carbohydrate metabolism: evidence for an indirect hemodynamic mechanism. Hepatology 1993, 18:1410-1415.
27. Ji S, Beckh K, Jungermann K: Regulation of oxygen consumption and microcirculation by a-sympathetic nerves in isolated perfused rat liver. FEBS Lett 1984; 167:117-122.
28. Beckh K, Otto R, Ji S, Jungermann K: Control of oxygen uptake, microcirculation and glucose release by circulating noradrenaline in perfused rat liver. Biol Chem Hoppe-Seyler 1985, 366:671-678.
29. Chiu AT, McCall DE, Price WE, Wong PC, Carini DJ, Duncia JV, et al.: Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent. J Pharmacol Exp Ther 1990, 252:711-718.
30. Wong PC, Price WA, Chiu AT, Duncia JV, Carini DJ, Wexler RR, et al.: Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP 753, an orally active antihypertensive agent. J Pharmacol Exp Ther 1990, 252:719-725.
31. Bergmeyer H-U: Editor. Method of Enzymatic Analysis. New York: Academic Press; 1974.
32. Hase T, Brim J: Observations on the microcirculatory architecture of the rat liver. Anal Rec 1966, 156 :157-174
33. Yamamoto K, Sherman I, Phillips MJ, Fisher MM: Three- dimensional observations of the hepatic arterial terminations in rat, hamster and human liver by scanning electron microscopy of microvascular casts. Hepatology 1985, 5:452-456.
34. Watanabe Y, Püschel GP, Gardemann A, Jungermann K: Preand proximal intrasinusoidal confluence of hepatic artery and portal vein in rat liver: functional evidence by orthograde and retrograde bivascular perfusion. Hepatology 1994, 19:1198-1207.
35. Lautt WW, Daniels TR: Differential effect of taurocholic acid on hepatic arterial resistance vessels and bile flow. Am J Physiol 1983, 244:G366-G369.
36. Lautt WW, Legare DJ, Daniels TR: The comparative effects of administration of substances via the hepatic artery or portal vein on hepatic arterial resistance, liver blood volume and hepatic extraction in cats. Hepatology 1984, 4:927-932.
37. Jungermann K, Katz N: Functional specialization of different hepatocyte populations. Physiol Rev 1989, 69:708-764.
38. Nussberger J, Brunner DB, Waeber B, Brunner HR: In vitro renin inhibition to prevent generation of angiotensins during determination of angiotensin I and II. Life Sci 1988, 42:1683-1688.
39. Ambrosioni E, Bacchelli S, Degli Esposti D, Borghi C: ACE-inhibitors and atherosclerosis. Eur J Epidemiol 1992, 8 (Suppl 2):129-133.