Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a Rac/RhoGDI complex

Molecular Biology of the Cell

Volumn 7, Issue 3, 1996, Pages 397-408

  O'Sullivan, Antony J ^a   Brown, Anna M ^a   Freeman, H Neil M ^b   Gomperts, Bastien D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYTOSOL PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); N ACETYL BETA GLUCOSAMINIDASE; STREPTOLYSIN O; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATTLE; CHROMATOGRAPHY; MAST CELL; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PURIFICATION; PROTEIN SECRETION;

EID: 0029876343     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.3.397     Document Type: Article

References (53)

1. rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane. Biochem. J. 298, 585-591.
2. Ali, S.M , and Burgoyne, R.D. (1990). The stimulatory effect of calpactin (annexin II) on calcium-dependent exocytosis in chromaffin cells: requirement for both the N-terminal and core domains of p36 and ATP. Cell. Signalling 2, 265-276.
3. Aridor, M., Traub, L.M., and Sagi-Eisenberg, R. (1990). Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins. J. Cell Biol. 111, 909-917.
4. E(i3) stimulates final steps in regulated exocytosis. Science 262, 1569-1572.
5. Barrowman, M.M., Cockcroft, S., and Gomperts, B.D (1986). Two roles for guanine nucleotides in the stimulus secretion sequence of neutrophils. Nature 319, 504-507.
6. Bokoch, G.M., Bohl, B.P., and Chuang, T.H. (1994). Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. J. Biol. Chem. 269, 31674-31679.
7. Bond, R.A., et al. (1995). Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β-adrenoceptor. Nature 374, 272-276.
8. Bowman, E.P., Uhlinger, D.J., and Lambeth, J.D. (1993). Neutrophil phospholipase D is activated by a membrane-associated rho family small molecular weight GTP-binding protein. J. Biol. Chem. 268, 21509-21512.
9. Bromberg, Y., Shani, E., Joseph, G., Gorzalczany, Y., Sperling, O., and Pick, E. (1994). The GDP-bound form of the small G protein rac1 is a potent activator of the superoxide-forming NADPH oxidase of macrophages. J. Biol. Chem. 269, 7055-7058.
10. 2+. Biochem. J. 275, 127-131.
11. 2+ and guanine nucleotides. J. Immunol. 147, 1905-1911.
12. Didsbury, J., Weber, R.F., Bokoch, G.M., Evans, T., and Snyderman, R. (1989). rac: a novel ras-related family of proteins that are botulinum toxin substrates. J. Biol. Chem. 264, 16378-16382.
13. Dormer, R.L., and Ashcroft, S.J.H. (1974). Studies on the role of calcium ions in the stimulation by adrenaline of amylase release from rat parotid. Biochem. J. 144, 543-550.
14. 2+ and GTP. Biosci. Rep. 7, 369-381.
15. Gomperts, B.D., and Tatham, P.E.R. (1988). GTP-binding proteins in the control of exocytosis. Cold Spring Harbor Symp. Quant. Biol. 53, 983-992.
16. Gomperts, B.D., and Tatham, P.E.R. (1992). Regulated exocytotic secretion from permeabilized cells. In: Methods in Enzymology, ed. J. Rothman, New York: Academic Press, 178-189.
17. Hall, A. (1994). Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol. 10, 31-54.
18. 2+-activated secretion. Nature 374, 173-177.
19. 2+-activated secretion. Nature 366, 572-575.
20. 2+ and guanine nucleotides in exocytotic secretion from permeabilized mast cells. J. Cell Biol. 105, 191-197.
21. 2+ at concentrations buffered in the micromolar range. Biochim. Biophys. Acta 927, 177-183.
22. Isomura, M., Kikuchi, A., Ohga, N., and Takai, Y. (1991). Regulation of binding of rhoB p20 to membranes by its specific regulatory protein, GDP dissociation inhibitor. Oncogene 6, 119-124.
23. Kinsella, B.T., Erdman, R A., and Maltese, W.A. (1991). Carboxyterminal isoprenylarion of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA. J. Biol. Chem. 266, 9786-9794.
24. Knight, D.E., and Baker, P.F. (1982). Calcium dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields. J. Membr. Biol. 68, 107-140.
25. Koffer, A., and Gomperts, B.D. (1989). Soluble proteins as modulators of the exocytotic reaction of permeabilized rat mast cells. J. Cell Sci. 94, 585-591.
26. Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
27. 2+ is a modulator, in the exocytotic reaction of permeabilised rat mast cells. Biochem. J. 288, 181-187.
28. Lillie, T.H.W., and Gomperts, B.D. (1992b). Nucleotides and divalent cations as effectors and modulators of exocytosis in permeabilised rat mast cells. Phil. Trans. Roy. Soc. Lond. B. 336, 25-34.
29. Lindau, M., and Gomperts, B.D. (1991). Techniques and concepts in exocytosis: focus on mast cells. Biochim. Biophys. Acta 1071, 429-471.
30. Manser, E., Leung, T., Salihuddin, H., Zhao, Z., and Lim, L. (1994). A brain serine/threonine protein kinase activated by cdc42 and rac1. Nature 367, 40-46.
31. Marquardt, D.L., Gruber, H.E., and Walker, L.L. (1987). Ribavirin inhibits mast cell mediator release. J. Pharmacol. Exp. Ther. 240, 145-149.
32. Matsuda, M., Okabe, T., Sugimoto, N., Senda, T., and Fujita, H. (1994). Tetanus toxin and Clostridium perfringens enterotoxin as tools for the study of exocytosis. Ann. NY Acad Sci 710, 94-106.
33. Matsudaira, P. (1987). Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. J. Biol. Chem. 262, 10035-10038.
34. 1 adrenergic receptors. Biochem. Pharmacol. 37, 3790-3793.
35. 2+-dependent exocytosis in chromaffin cells. EMBO J. 12, 3747-3752.
36. Morgan, A., and Burgoyne, R.D. (1992). Interaction between protein kinase C and Exo1 (14-3-3 protein) and its relevance to exocytosis in permeabilized adrenal chromaffin cells. Biochem. J. 286, 807-811.
37. Morrissey, J.H. (1981). Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. Anal. Biochem. 117, 307-310.
38. Neuhoff, V., Arold, N., Taube, D., and Ehrhardt, W. (1988). Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie brilliant blue G-250 and R-250. Electrophoresis 9, 255-262.
39. 2+-dependent secretion by protein kinase C. J. Biol. Chem. 33, 23972-23981.
40. Nobes, C.D., and Hall, A. (1995). Rho, Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia and filopodia. Cell 81, 53-62.
41. Norman, J.C., Price, L.S., Ridley, A.J., Hall, A., and Koffer, A. (1994). Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins. J. Cell Biol. 126, 1005-1015.
42. Nüsse, O., Lindau, M., Cromwell, O., Kay, A.B., and Gomperts, B.D. (1990) Intracellular application of GTP-5′-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils. J. Exp. Med. 171, 775-786.
43. Price, L.S., Norman, J.C., Ridley, A.J., and Koffer, A. (1995). Small GTPases, rac and rho, as regulators of secretion in mast cells. Curr. Biol. 5, 68-73.
44. Roth, D., Morgan, A., and Burgoyne, R.D. (1993). Identification of a key domain in annexin and 14-3-3 proteins that stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells. FEBS Lett. 320, 207-210.
45. Saito, H., Okajima, F., Molski, T.F.P., Sha'afi, R.I., Ui, M., and Ishizaka, T. (1987). Effects of ADP-ribosylation of GTP-binding protein by pertussis toxin on immunoglobulin E-dependent and -independent histamine release from mast cells and basophils. J. Immunol. 138, 3927-3934.
46. Sarafian, T., Aunis, D., and Bader, M. (1987). Loss of proteins from digitonin-permeabilized adrenal chromaffin cells essential for exocytosis. J. Biol. Chem. 262, 16671-16676.
47. Schagger, H., and von Jagow, G. (1987). Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166, 368-379
48. Stutchfield, J., and Cockcroft, S. (1993). Correlation between secretion and phospholipase D activation in differentiated HL60 cells. Biochem. J. 293, 649-655.
49. Takai, Y., Kaibuchi, K., Kikuchi, A., and Kawata, M. (1992). Small GTP-binding proteins. Int. Rev. Cytol. 133, 187-230.
50. Tatham, P.E.R., and Gomperts, B.D. (1990). Cell permeabilization In: Peptide Hormones - A Practical Approach, ed. K. Siddle and J.C Hutton Oxford, UK: IRL Press, 257-269.
51. Thomsen, J., and Bayne, S. (1988). Microscale alkylation with 4-vinylpyridine. J. Prot. Chem. 7, 295-296.
52. Trifaro, J.M., Rodriguez-del-Castillo, A., and Vitale, M.L. (1992). Dynamic changes in chromaffin cell cytoskeleton as prelude to exocytosis. Mol. Neurobiol. 6, 339-358.
53. Wilson, B.S., Deanin, G.G., Standefer, J C., Vanderjagt, D., and Oliver, J.M. (1989). Depletion of guanine nucleotides with mycophenolic acid suppresses IgE receptor-mediated degranulation in rat basophilic leukemia cells. J. Immunol. 143, 259-265.