Stage-dependent expression of CD7, CD45RO, CD45RA and CD25 on CD4-positive peripheral blood T-lymphocytes in cutaneous T-cell lymphoma

Acta Dermato-Venereologica

Volumn 76, Issue 1, 1996, Pages 34-36

  Jakob, Thilo ^a,b   Neuber, Karsten ^a   Altenhoff, Jürgen ^a   Kowalzick, Lutz ^a   Ring, Johannes ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD7 ANTIGEN; INTERLEUKIN 2 RECEPTOR;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; PRIORITY JOURNAL; T CELL LYMPHOMA; T LYMPHOCYTE;

AGED; ANTIGENS, CD45; ANTIGENS, CD7; ANTIGENS, SURFACE; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; LYMPHOCYTOSIS; LYMPHOMA, T-CELL, CUTANEOUS; MALE; MIDDLE AGED; RECEPTORS, INTERLEUKIN-2; SKIN NEOPLASMS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0029876340     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Kung PC, Berger CL, Goldstein G, LoGerfo P, Edelson RL. Cutaneous T-cell lymphoma: characterization by monoclonal antibodies. Blood 1981; 57: 261-266.
2. Sterry W, Mielke V. CD4+ cutaneous T-cell lymphomas show the phenotype of helper/inducer T-cells (CD45RA- CD29w+). J Invest Dermatol 1989; 93: 413-416.
3. Wood GS, Abel EA, Hoppe RT, Wamke RA. Leu-8 and Leu-9 antigen phenotypes: immunologic criteria for the distinction of mycosis fungoides from cutaneous inflammation. J Am Acad Dermatol 1990; 14: 1006-1013.
4. Haynes BF, Metzgar RS, Minna JD, Bunn PA. Phenotypic characterisation of cutaneous T-cell lymphoma: use of monoclonal antibodies to compare with other malignant T-cells. N Engl J Med 1991; 304: 1319-1323.
5. Worner I, Matutes E, Beverley PCL, Catovsky D. The distribution of CD45R, CD29 and CD45RO (UCHL1) antigens in mature CD4 positive T-cell leukemias. Br J Haematol 1990; 74: 439-444.
6. Gilmore SJ, Benson EM, Kelly JW. T-cell subsets with a naive phenotype are selectively decreased in the peripheral blood of patients with mycosis fungoides. J Invest Dermatol 1991; 96: 50-56.
7. Wood GS, Hong SR, Sasaki DT, Abel EA, Hoppe RT, Warnke RA, et al. Leu-8/CD7 antigen expression by CD3+ T-cells: comparative analysis of skin and blood in mycosis fungoides/ Sézary syndrome relative to normal blood values. J Am Acad Dermatol 1990; 22: 602-607.
8. Lamberg SJ, Bunn PA, eds. Proceedings of the workshop on cutaneous T-cell lymphomas (mycosis fungoides and Sézary syndrome). Cancer Treat Rep 1979; 63: 561.
9. Kaudewitz P, Josimovic-Alasevic O, Diamantstein T, Eckert F, Klepzig K, Burg G. Soluble IL-2 receptor serum levels in cutaneous T-cell lymphoma: correlation with clinical stage and IL-2 receptor status in cutaneous infiltrates. J Invest Dermatol 1988; 91: 386-387.
10. Moll M, Reinhold U, Kukel S, Abken H, Müller R, Oltermann I, et al. CD7-negative helper T-cells accumulate in inflammatory skin lesions. J Invest Dermatol 1994; 102: 328-332.