A comparative study of peritoneal mast cells from mutant IL-4 deficient and normal mice: Evidence that IL-4 is not essential for mast cell development but enhances secretion via control of IgE binding and passive sensitization

Cytokine

Volumn 8, Issue 3, 1996, Pages 190-196

  Banks, E M S ^a   Coleman, J W ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Gene knockout mice; IgE; Il 4; Mast cells; Mediator release

Indexed keywords

IMMUNOGLOBULIN BINDING FACTOR; IMMUNOGLOBULIN E; INTERLEUKIN 4;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MATURATION; CELL SECRETION; COMPARATIVE STUDY; CONTROLLED STUDY; MAST CELL DEGRANULATION; MOUSE; MOUSE MUTANT; NONHUMAN; PERITONEUM MAST CELL; PRIORITY JOURNAL; SENSITIZATION;

ANIMALS; CELLS, CULTURED; CYTOPLASMIC GRANULES; FLOW CYTOMETRY; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN-4; KINETICS; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; PERITONEAL CAVITY; SEROTONIN;

ANIMALIA;

EID: 0029876032     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1996.0027     Document Type: Article

References (33)

1. Schwartz LB, Austen KF (1984) Structure and function of the chemical mediators of mast cells. Prog Allergy 34:271-321.
2. Burd PR, Rogers HW, Gordon JR, Martin CA, Jayaraman S, Wilson SD, Dvorak AM, Gailli SJ, Dorf ME (1989) IL-3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines. J Exp Med 170:245-257.
3. Plaut M, Pierce JH, Watson CJ, Hanley-Hyde J, Nordon RP, Paul WE (1989) Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores. Nature 339:64-67.
4. Gordon JR, Burd PR, Galli SJ (1990) Mast cells as a source of multifunctional cytokines. Immunol Today 11:458-463.
5. Galli SJ (1993) New concepts about the mast cell. New Eng J Med 328:257-265.
6. Galli SJ (1990) New insights into 'The riddle of the mast cells': microenvironmental regulation of mast cell development and phenotypic heterogeneity. Lab Invest 62:5-33.
7. Haig DM, McKee TA, Jarrett EEE, Woodbury R, Miller HRP (1982) Generation of mucosal mast cells is stimulated in vitro by factors derived from T cells of helminth infected rats. Nature 300: 188-190.
8. Ihle JN, Keller J, Oroszlan S, Henderson LE, Copeland RD, Fitch F, Prystowsky MB, Goldwasser E, Schrader JW, Palaszynski E, Dy M, Lebel B (1983) Biological properties of homogenous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell stimulating activity, colony-stimulating factor activity and histamine-producing cell-stimulating factor activity. J Immunol 131:282-287.
9. Tsai M, Shih L-S, Newlands GFJ, Takeishi T, Langley KE, Zsebo KM, Miller HRP, Geissler EN, Gailli SJ (1992) The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype. J Exp Med 174: 125-131.
10. Tsai M, Takeishi T, Thompson H, Langley KE, Zsebo KM, Metcalfe DD, Galli SJ (1991) Induction of mast cell proliferation, maturation and heparin synthesis by the c-kit ligand, stem factor. Proc Natl Acad Sci USA 88:6382-6386.
11. Galli SJ, Tsai M, Wershil BK (1993) The c-kit receptor, stem cell factor and mast cells. What each is telling us about the others. Am J Path 142:965-974.
12. Hamaguchi Y, Kanakura Y, Fujita J, Takeda S-I, Nakano T, Tarui S, Honjo T, Kitamura Y (1987) Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells. J Exp Med 165:268-273.
13. Tsuji K, Nakahata T, Takagi M, Kobayashi T, Ishiguro A, Kikuchi T, Naganuma K, Koike K, Miyajima A, Ken-Ichi A, Akabane T (1990) Effects of interleukin-3 and interleukin-4 on the development of 'connective tissue-type' mast cells: Interleukin-3 supports their survival and interleukin-4 triggers and supports their proliferation synergistically with interleukin-3. Blood 75:421-427.
14. Takagi M, Koike K, Nakahata T (1990) Antiproliferative effect of IFN-γ on proliferation of mouse connective tissue-type mast cells. J Immunol 145:1880-1884.
15. Coleman JW, Holliday MR, Kimber I, Zsebo KM, Galli SJ (1993) Regulation of mouse peritoneal mast cell secretory function by stem cell factor, IL-3 or IL-4. J Immunol 150:556-562.
16. Coleman JW, Buckley MG, Holliday MR, Morris AG (1991) Interferon-γ inhibits serotonin release from mouse peritoneal mast cells. Eur J Immunol 21:2559-2564.
17. Holliday MR, Banks EMS, Dearman RJ, Kimber I, Coleman JW (1994) Interactions of IFN-γ with IL-3 and IL-4 in the regulation of serotonin and arachidonate release from mouse peritoneal mast cells. Immunology 82:70-74.
18. Buckley MG, Williams CMM, Thompson J, Pryor P, Ray K, Butterfield JH, Coleman JW (1995) IL-4 enhances IL-3 and IL-8 gene expression in a human leukemic mast cell line. Immunology 84: 410-415.
19. Holliday MR, Dearman RJ, Kimber I, Coleman JW (1993) Sensitization of mice to chemical allergens modulates the responsiveness of isolated mast cells to IgE-dependent activation. Immunology 78:508-510.
20. Kopf M, Le Gros G, Bachmann M, Lamers MC, Bluethmann H, Kohler G (1993) Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362:245-248.
21. Kühn R, Rajewsky K, Müller W (1991) Generation and analysis of interleukin-4 deficient mice. Science 254:707-710.
22. Shore PA, Burkhalter A, Cohn VH (1959) A method for the fluorometric analysis of histamine in tissues. J Pharm Exp Ther 127:182-186.
23. Kulczycki A, Metzger H (1974) The interaction of IgE with rat basophilic leukaemia cells. II. Quantitative aspects of the binding reaction. J Exp Med 140:1676-1695.
24. Conrad DH, Bazin H, Sehon AH, Froese A (1975) Binding parameters of the interaction between rat IgE and rat mast cell receptors. J Immunol 114:1688-1691.
25. Rennick D, Hunte B, Holland G, Thompson-Snipes L (1995) Cofactors are essential for stem cell factor-dependent growth and maturation of mast cell progenitors: Comparative effects of interleukin-3 (IL-3), IL-4, IL-10, and fibroblasts. Blood 85:57-65.
26. Haig DM, Huntley JF, MacKellar A, Newlands GFJ, Inglis L, Sangha R, Cohen D, Hapel A, Galli SJ, Miller HRP (1994) Effects of stem cell factor (Kit-ligand) and interleukin-3 on the growth and serine proteinase expression of rat bone-marrow-derived or serosal cells. Blood 83:72-83.
27. Thompson-Snipes L, Dhar V, Bond MW, Mosmann TR, Moore KM, Rennick DM (1991) Interleukin 10: a novel stimulatory factor for mast cells and their progenitors. J Exp Med 173:507-510.
28. Vercelli D, Jabara HH, Lee B-W, Woodland N, Geha RS, Leung DYM (1988) Human recombinant interleukin 4 induces FcεR2/CD23 on normal human monocytes. J Exp Med 167: 1406-1416.
29. Finkelman FD, Katona IM, Urban JF, Holmes J, Ohara J, Tung AS, Sample JvG, Paul WE (1988) IL-4 is required to generate and sustain in vivo IgE responses. J Immunol 141:2335-2341.
30. Lebman DA, Coffman RL (1988) Interleukin 4 causes isotype switching to IgE in T cell stimulated clonal B cell cultures. J Exp Med 168:853-862.
31. Mosmann TR, Coffman RL (1989) Heterogeneity of cytokine secretion patterns and function of helper T cells. Adv Immunol 46:111-147.
32. Paul WE (1991) Interleukin-4: a prototypic immunoregulatory lymphokine. Blood 77:1859-1870.
33. Bradding P, Feather IH, Howarth PH, Muellr R, Roberts JA, Britten K, Bews JPA, Hunt TC, Okayama Y, Heusser CH, Bullock GR, Church MK, Holgate ST (1992) Interleukin 4 is localised to and released by human mast cells. J Exp Med 176:1381-1386.