New 'state' markers for the detection of alcoholism

Alcohol and Alcoholism

Volumn 31, Issue SUPPL. 1, 1996, Pages 59-62

  Lesch, Otto M ^a   Walter, Henriette ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; TRANSFERRIN; BIOLOGICAL MARKER; CARBOHYDRATE DEFICIENT TRANSFERRIN; CARBOHYDRATE-DEFICIENT TRANSFERRIN; DRUG DERIVATIVE;

ALCOHOL ABUSE; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; CONFERENCE PAPER; DISEASE PREDISPOSITION; HUMAN; LABORATORY TEST; MEDICAL RESEARCH; PRIORITY JOURNAL; RELAPSE; SCREENING TEST; BLOOD; DRINKING BEHAVIOR; GENETIC PREDISPOSITION; GENETICS; REPRODUCIBILITY; REVIEW; SENSITIVITY AND SPECIFICITY;

ALCOHOL DRINKING; ALCOHOLISM; BIOLOGICAL MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRANSFERRIN;

EID: 0029875832     PISSN: 07350414     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.alcalc.a008220     Document Type: Conference Paper

References (26)

1. Allen, J. P., Litten, R. Z., Anton, R. F. and Cross, G. M. (1994) Carbohydrate-deficient transferrin as a measure of immoderate drinking: remaining issues. Alcoholism: Clinical and Experimental Research 18, 799-812.
2. Behrens, U. J., Worner, T. M., Braly, L. F., Schaffner, F. and Lieber, C. S. (1988) Carbohydrate-deficient transferrin, a marker for chronic alcohol consumption in different ethnic populations. Alcoholism: Clinical and Experimental Research 12, 427-432.
3. Bell, H., Tallaksen, C. H., Sjaheim, T., Weberg, R., Raknerud, N., Orjasaeter, H., Try, H. and Haug, E. (1993) Serum carbohydrate-deficient transferrin as a marker of alcohol consumption in patients with chronic liver diseases. Alcoholism: Clinical and Experimental Research 17, 246-252.
4. Bonte, W., Lesch, O. M. and Sprung, R. (1987) Alcoholism equals methanolism. Journal of the Canadian Society of Forensic Science 20, 74.
5. Borg, S. (1993) Carbohydrate-deficient transferrin (CDT TM), a specific marker for high alcohol consumption. Alcohologia 5, 117-120.
6. Borg, S., Beck, O., Helander, A., Voltaire, A. and Stibler, H. (1992) Carbohydrate-deficient transferrin and 5-hydroxytryptophol: two new markers of high alcohol consumption. In Measuring Alcohol Consumption, Litten, R. and Allen, J. eds, pp. 149-159. The Humana Press Inc., Totowa, NJ.
7. Grünberger, J., Linzmayer, L., Saletu, B. and Lesch, O. M. (1989) Klinische psychophysiologische Diagnostik bei ambulanten Alkoholikern. Statische und lichtevozierte dynamische Pupillometrie. Wiener Zeitschrift für Suchtforschung 12, 53-62.
8. Leitner, A., Gierth, L., Lentner, S., Platz, W. E., Rommelspacher, H., Schmidt, L. G., and Lesch, O. M. (1994) Untergruppen alkoholkranker. Gibt es biologische Marker? Harman und Norharmanbefunde. In Biologische Psychiatrie der Gegenwart, Baumann, P. ed., pp. 636-640. Springer-Verlag, Vienna.
9. Lesch, O. M. (1985) Alkoholismus. Typen und ihr Verlauf. Eine Langzeitstudie. Thieme Verlag Copythek, Stuttgart.
10. Lesch, O. M., Lesch, E., Dietzel, M., Mader, R., Musalek, M., Walter, H. and Zeiler, K. (1986) Chronischer alkoholismus-Alkoholfolgekrankheiten-Todesursachen. Wiener Medizinische Wochenschrift 19, 505-515.
11. Lesch, O. M., Walter, H., Bonte, W., Grünberger, J., Musalek, M. and Sprung, R. (1991) Etiology of subgroups in chronic alcoholism and different mechanisms in transmitter systems. In Alcoholism: A Molecular Perspective, Vol. 206, Palmer, T. N. ed., pp. 145-160. Plenum Press, New York.
12. Lesch, O. M., Walter, H., Antal, J., Kanitz, R. D., Kovacz, A., Marx, B., Neumeister, A., Saletu, M., Semler, B., Stumpf, I. and Mader, R. (1996a) Alcohol dependence. Is CDT a marker for alcohol intake? Alcohol and Alcoholism 31, in press.
13. Lesch, O. M., Walter, H., Freitag, H., Heggli, D. E., Leitner, A., Mader, R., Neumeister, A., Passweg, V., Pusch, H., Semler, B., Sundrehagen, E. and Kasper, S. (1996b) CDT as a screening marker for drinking in a general hospital population. Alcohol and Alcoholism 31, in press.
14. Lesch, O. M., Walter, H., Antal, J., Heggli, D. E., Kovacz, A., Leitner, A., Neumeister, A., Stumpf, I., Sundrehagen, E. and Kasper, S. (1996c) CDT as a marker for alcohol intake in a study with healthy subjects. Alcohol and Alcoholism 31, in press.
15. Litten, R. and Allen, J., eds. (1992) Measuring Alcohol Consumption. The Humana Press Inc., Totowa, NJ.
16. Löf, K., Seppä, K., Itälä, L., Koivula, T., Turpeinen, U. and Sillanaukee, P. (1994) Carbohydrate-deficient transferrin as an alcohol marker among female heavy drinkers: a population-based study. Alcoholism: Clinical and Experimental Research 18, 889-894.
17. Musshoff, F. (1995) Formaldehyd-Neuroamin Kondensationsprodukte bei chronischen Alkoholikern, 1st ed. Hans Joachim Köster, Berlin.
18. Poldrugo, F., Chick, J. D., Moore, N. and Walburg, J. A. (1993) Mortality studies in the long-term evaluation of treatment of alcoholics. Alcohol and Alcoholism 28 (Suppl. 2), 151-155.
19. Poupon, R. E., Schellenberg, F., Nalpas, B. and Weill, J. (1989) Assessment of the transferrin index in screening heavy drinkers from a general practice. Alcoholism: Clinical and Experimental Research 13, 549-553.
20. Rommelspacher, H., Schmidt, L. G. and May, T. (1991) Plasma norharman (β-carboline) levels are elevated in chronic alcoholics. Alcoholism: Clinical and Experimental Research 15, 553-559.
21. Rosman, A. S. and Lieber, C. S. (1992) An overview of current and emerging markers of alcoholism. In Measuring Alcohol Consumption, Litten, R. and Allen, J. eds, pp. 99-134. The Humana Press Inc., Totowa, NJ.
22. Schmidt, L. G. and Rommelspacher, H. (1990) Biologische marker des alkoholismus. Nervenarzt 61, 140-147.
23. Stibler, H. and Borg, S. (1986) Carbohydrate composition of transferrin in alcoholic patients. Alcoholism: Clinical and Experimental Research 10, 61-64.
24. Stibler, H. and Borg, S. (1988) The value of carbohydrate-deficient transferrin as a marker of high alcohol consumption. In Biochemical and Social Aspects of Alcohol and Alcoholism, Kuriyama, K., Takada, A., Ishii, H. eds, pp. 503-506. Elsevier, Amsterdam.
25. Stibler, H., Borg, S. and Allgulander, C. (1979) Clinical significance of abnormal heterogeneity of transferrin in relation to alcohol consumption. Acta Medica Scandinavica 206, 275-281.
26. Stibler, H., Borg, S. and Joustra, M. (1986) Micro anion exchange chromatography of carbohydrate-deficient transferrin in serum in relation to alcohol consumption (Swedish Patent 8400587-5). Alcoholism: Clinical and Experimental Research 10, 535-544.