11-Oxo-tetrodotoxin and a specifically labelled 3H-tetrodotoxin

Toxicon

Volumn 34, Issue 4, 1996, Pages 407-416

  Wu, B Q ^a   Yang, L ^a   Kao, C Y ^a   Levinson, S R ^b   Yotsu Yamashita, M ^c   Yasumoto, T ^c  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL; TETRODOTOXIN; TOXIN; TRACER; TRITIUM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE RESPONSE; EEL; ELECTROPHYSIOLOGY; ELECTROPLAQUE; FROG; ISOTOPE LABELING; LIGAND BINDING; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SKELETAL MUSCLE; TOXIN SYNTHESIS;

EID: 0029875632     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(95)00168-9     Document Type: Article

References (21)

1. Agnew, W. S., Levinson, S. R., Brabson, J. S. and Raftery, M. A. (1978) Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes. Proc. natn. Acad. Sci. U.S.A. 75, 2606-2611.
2. Balerna, M., Lombet, A., Chicheportiche, R., Romey, G. and Lazdunski, M. (1981) Synthesis and properties of new photoactivable derivatives of tetrodotoxin. Biochim. biophys. Acta 664, 210-225.
3. Chicherportiche, R., Balerna, M., Lombet, A., Romey, G. and Lazdunski, M. (1980) Synthesis of new highly radioactive tetrodotoxin derivatives and their binding properties to the sodium channel. Eur. J. Biochem. 104, 617-625.
4. Daumas, P., Andersen, O. S., Wu, B. Q. and Kao, C. Y. (1992) Block of sodium channel by 11-oxo-tetrodotoxin, a semisynthetic analog of tetrodotoxin. Biophys. J. 62, A111.
5. Hille, B. and Campbell, D. T. (1976) An improved vaseline-gap voltage clamp for skeletal muscle fiber. J. gen. Physiol. 67, 265-293.
6. Hu, S. L. and Kao, C. Y. (1989) Interactions of neosaxitoxin with the sodium channel of the frog skeletal muscle fiber. J. gen. Physiol. 97, 561-578.
7. + channels in muscle surface and T-tribule membranes revealed by tetrodotoxin derivatives. Pflügers Arch. 397, 1-5.
8. Kao, C. Y. (1966) Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena. Pharmac. Rev. 18, 997-1049.
9. Kao, C. Y. and Levinson, S. R. (1986) Tetrodotoxin, Saxitoxin and the Molecular Biology of the Sodium Channel, Vol. 479. New York: New York Academy of Science.
10. Khora, S. S. and Yasumoto, T. (1989) Isolation of 11-oxotetrodotoxin from the puffer, Anthron nigropuntatus. Tetrahedron Lett. 30, 4393-4394.
11. Levinson, S. R. (1975) The purity of tritiated tetrodotoxin as determined by bioassay. Phil. Trans. R. Soc. Lond. 270, 337-348.
12. Levinson, S. R., Curatalo, C. J., Reed, J. and Raftery, M. A. (1979) A rapid and precise assay for tetrodotoxin binding to detergent extracts of excitable tissues. Analyt. Biochem. 99, 72-84.
13. Miller, J. A., Agnew, W. S. and Levinson, S. R. (1983) Principal glycopeptide of the tetrodotoxin/saxitoxin binding protein from Electrophorus electricus: isolation and partial chemical and physical characterization. Biochemistry 22, 462-470.
14. + channels by guanidinium toxins. J. gen. Physiol. 84, 687-704.
15. Mosher, H. S. (1986) The chemistry of tetrodotoxin. In: Tetrodotoxin, Saxitoxin and the Molecular Biology of the Sodium Channel, Vol. 479, pp. 32-43 (Kao, C. Y. and Levinson, S. R., Eds). New York: New York Academy of Science.
16. Ogura, Y. (1958) Some recent problems with fugu-toxin, particularly on crystalline tetrodotoxin. Seitai no Kagaku (Japan) 9, 281-287.
17. Ritchie, J. M., Rogart, R. B. and Strichartz, G. R. (1976) A new method for labelling saxitoxin and its binding to non-myelinated fibers of rabbit vagus, lobster walking leg, and garfish olfactory nerves. J. Physiol., Lond. 261, 477-494.
18. Wagner, H. H. and Ulbricht, W. (1975) Rates of saxitoxin action and saxitoxin-tetrodotoxin interaction at the node of Ranvier. Pflügers Arch. 359, 297-315.
19. Wu, B. Q., Yang, L., Kao, C. Y., Yotsu, M. and Yasumoto, T. (1991) 11-Oxo-tetrodotoxin, a potent analogue of tetrodotoxin. Biophys. J. 59, A261.
20. Yang, L. and Kao, C. Y. (1992) Actions of chiriquitoxin on frog skeletal muscle fibers and implications for the tetrodotoxin/saxitoxin receptor. J. gen. Physiol. 100, 609-622.
21. Yasumoto, T. and Michishita, T. (1985) Fluorometric determination of tetrodotoxin by high performance liquid chromatography. Agric. Biol. Chem. 49, 3077-3080.