Evidence for a pivotal role of platelets in vascular reocclusion and restenosis

Cardiovascular Research

Volumn 31, Issue 2, 1996, Pages 235-236

  LeBreton, Herve ^a   Topol, Eric ^a   Plow, Edward F ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Coronary angioplasty; Platelets; Restenosis; Thrombin

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ALTEPLASE; FIBRINOLYTIC AGENT; HEPARIN; STREPTOKINASE; THROMBIN; THROMBIN INHIBITOR; TICLOPIDINE;

CORONARY ARTERY DISEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECURRENT DISEASE; SHORT SURVEY; STENOSIS; THROMBOCYTE;

ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BLOOD PLATELETS; CORONARY THROMBOSIS; HUMANS; PLATELET AGGREGATION INHIBITORS; RECURRENCE; THROMBOLYTIC THERAPY;

EID: 0029875367     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/0008-6363(96)00005-3     Document Type: Short Survey

References (9)

1. Meijer A, Verheugt FW, Werter CJPJ, Lie KI, Van Der Pol JM, Van Eenige MJ. Aspirin versus coumadin in the prevention of reocclusion and recurrent ischemia after successful thrombolysis: a prospective placebo-controlled angiographic study. Results of the APRICOT study. Circulation 1993;87:1524-30.
2. Lincoff AM, Popma JJ, Ellis SG, Hacker JA, Topol EJ. Abrupt vessel closure complicating coronary angioplasty: clinical, angiographic, and therapeutic profile. J Am Coll Cardiol 1992;19:926-35.
3. ISIS-2 Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17, 187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988;13:349-60.
4. Kleiman NS, Ohman EM, Califf RM, et al. Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after-thrombolytic therapy. J Am Coll Cardiol 1993;22:381-9.
5. Ohman EM, Kleiman NS, Talley JD, et al. for the IMPACT AMI Study Group. Simultaneous platelet glycoprotein IIb/IIa integrin blockade with accelerated tissue plasminogen activator in acute myocardial infarction. Circulation 1994;90(Suppl II):I-564.
6. The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med 1994;1994:956-61.
7. Topol EJ, Califf RM, Weisman HF, et al. Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: results at six months. Lancet 1994;343:881-886.
8. Serruys PW, Hermann JP, Simon R, et al. A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. N Engl J Med 1995;333:757-63.
9. Nicolini FA, Lee P, Rios G, Kottke-Marchant K, Topol EJ. Combination of platelet fibrinogen receptor antagonist and direct thrombin inhibitor at low doses markedly improves thrombolysis. Circulation 1994;89:1802-1809.