Synthesis and pharmacological properties of 1,2,3,4-tetrahydroisoquinoline derivatives

Acta Poloniae Pharmaceutica - Drug Research

Volumn 53, Issue 1, 1996, Pages 25-29

  Brzezińska, Elzbieta ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

2 isopropyl 4,6,8 trihydroxy 1,2,3,4 tetrahydroisoquinoline derivatives; Biological activity

Indexed keywords

2 ISOPROPYL 4,6,8 TRIHYDROXY 1,2,3,4 TETRAHYDROISOQUINOLINE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRONCHODILATING ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FEMALE; GUINEA PIG; HEART ATRIUM; MALE; NONHUMAN; RAT; SMOOTH MUSCLE RELAXATION; TRACHEA;

ADRENERGIC BETA-AGONISTS; ALDEHYDES; ANIMALS; BINDING SITES; BRONCHODILATOR AGENTS; CEREBRAL CORTEX; DRUG DESIGN; FEMALE; GUINEA PIGS; ISOPROTERENOL; ISOQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMBRANE PROTEINS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-2; REFERENCE STANDARDS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROISOQUINOLINES; TRACHEA;

EID: 0029875304     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Cohen G., Mytilineou C., Barret R.: Science 175, 1269 (1972).
2. Kaiser C., Oh H.J., Garcia-Slanga B.J., Silpizo A.C., Hieble I.P., Wawro J.E., Kruse J.: J. Med. Chem. 29, 2381 (1986).
3. Clarc M.T., Chang J., Navran S., Huzoor-Akbar, Mukhopadhay, Amin H., Filler D., Miller D.: J. Med. Chem. 29, 181 (1986).
4. Yamada KK., Ikezaki M., Umino N., Ohtsuka H., Itoh N., Ikezawa K., Kiyomoto A., Iwakuma T.: Chem. Pharm. Bull. Tokyo 29, 744 (1981).
5. Yamada K., Itoh N., Ikezawa K.: Chem. Pharm. Bull. 29, 1848 (1981).
6. Fedyna J.S., Adejare A., Miller D.D., Feller D.R.: Eur. J. Pharmacol. 135, 161 (1987).
7. Yamada K., Tekeda M., Itoh N.: Chem. Pharm. Bull. 30, 1588 (1982).
8. Brzezińska E.: Acta Polon. Pharm. 51, 137 (1994).
9. Ariens E.J., Van Rossum J.M.: Arch. Int. Pharmacodyn. 110, 275 (1957).
10. Van Rossum J.M.: Arch. Int. Pharmacodyn. Ther. 143, 299 (1963).
11. Wu E.S.C., Cole T.E., Davidson T.A.: J. Med. Chem. 30, 788 (1987).
12. Lowry O.H., Rosebrough N.J., Farr F.L., Raudall R.J.: J. Biol. Chem. 193, 265 (1951).