-
1
-
-
0028227962
-
Role of abnormally phosphorylated tau in the breakdown of microtubule in Alzheimer disease
-
Alonso AC, Zaidi T, Grundke-Iqbal I, Iqbal K (1994): Role of abnormally phosphorylated tau in the breakdown of microtubule in Alzheimer disease. Proc Natl Acad Sci USA 91:5562-5566.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5562-5566
-
-
Alonso, A.C.1
Zaidi, T.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
2
-
-
0027757042
-
Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases like cdk2 and cdk5
-
Baumann K, Mandelkow E-M, Biernat J, Piwnica-Worms H, Mandelkow E (1993): Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases like cdk2 and cdk5. FEBS Lett 336:417-424.
-
(1993)
FEBS Lett
, vol.336
, pp. 417-424
-
-
Baumann, K.1
Mandelkow, E.-M.2
Biernat, J.3
Piwnica-Worms, H.4
Mandelkow, E.5
-
3
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
Biernat J, Mandelkow E-M, Schroter C, Lichtenberg-Kraag B, Steiner B, Berling B, Meyer H, Vandermeeren A, Goedert M, Mandelkow E (1992): The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J 11:1593-1597.
-
(1992)
EMBO J
, vol.11
, pp. 1593-1597
-
-
Biernat, J.1
Mandelkow, E.-M.2
Schroter, C.3
Lichtenberg-Kraag, B.4
Steiner, B.5
Berling, B.6
Meyer, H.7
Vandermeeren, A.8
Goedert, M.9
Mandelkow, E.10
-
4
-
-
0027338266
-
262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
-
262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding. Neuron 11:153-163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.-M.4
Mandelkow, E.5
-
5
-
-
0027308924
-
Abnormal tau phosphorylation at Ser-396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
-
Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee VM-Y (1993): Abnormal tau phosphorylation at Ser-396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron 10:1089-1099.
-
(1993)
Neuron
, vol.10
, pp. 1089-1099
-
-
Bramblett, G.T.1
Goedert, M.2
Jakes, R.3
Merrick, S.E.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
6
-
-
0026549985
-
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state
-
Drewes G, Lichten-Kraag B, Doring F, Mandelkow E-M, Biernat J, Goris J, Doree M, Mandelkow E (1992): Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state. EMBO J 11:2131-2138.
-
(1992)
EMBO J
, vol.11
, pp. 2131-2138
-
-
Drewes, G.1
Lichten-Kraag, B.2
Doring, F.3
Mandelkow, E.-M.4
Biernat, J.5
Goris, J.6
Doree, M.7
Mandelkow, E.8
-
7
-
-
0027753055
-
Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A
-
Drewes G, Mandelkow E-M, Baumann K, Goris J, Merlevede W, Mandelkow E (1993): Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A. FEBS Lett 336:425-432.
-
(1993)
FEBS Lett
, vol.336
, pp. 425-432
-
-
Drewes, G.1
Mandelkow, E.-M.2
Baumann, K.3
Goris, J.4
Merlevede, W.5
Mandelkow, E.6
-
8
-
-
0027184294
-
Transglutaminase catalyzes the formation of sodium dodecyl sulfate insoluble, Alz-50-reactive polymers of tau
-
Dudek SM, Johnson GV (1993): Transglutaminase catalyzes the formation of sodium dodecyl sulfate insoluble, Alz-50-reactive polymers of tau. Neurochem 61:1159-1162.
-
(1993)
Neurochem
, vol.61
, pp. 1159-1162
-
-
Dudek, S.M.1
Johnson, G.V.2
-
9
-
-
0028173238
-
Tau phosphorylation in human, primate, and rat brain: Evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro
-
Garver TD, Harris KA, Lehman RAW, Lee VM-Y, Trojanowski JQ, Billingsley ML (1994): Tau phosphorylation in human, primate, and rat brain: Evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro. J. Neurochem 63:2279-2284.
-
(1994)
J. Neurochem
, vol.63
, pp. 2279-2284
-
-
Garver, T.D.1
Harris, K.A.2
Lehman, R.A.W.3
Lee, V.M.-Y.4
Trojanowski, J.Q.5
Billingsley, M.L.6
-
10
-
-
85062139768
-
Tau phosphorylation in brain slices: Pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated kinase
-
Garver TD, Oyler GA, Harris KA, Polavarapu RG, Damuni Z, Lehman RAW, Billingsley ML (1995): Tau phosphorylation in brain slices: Pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated kinase. Mol Pharmacol 47:745-756.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 745-756
-
-
Garver, T.D.1
Oyler, G.A.2
Harris, K.A.3
Polavarapu, R.G.4
Damuni, Z.5
Lehman, R.A.W.6
Billingsley, M.L.7
-
11
-
-
0025600995
-
Expression of separate isoforms of human tau protein: Correlation with the human tau pattern in brain and effects on tubulin polymerization
-
Goedert M, Jakes R (1990): Expression of separate isoforms of human tau protein: Correlation with the human tau pattern in brain and effects on tubulin polymerization. EMBO J 9:4225-4230.
-
(1990)
EMBO J
, vol.9
, pp. 4225-4230
-
-
Goedert, M.1
Jakes, R.2
-
12
-
-
0002792366
-
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
-
Goedert M, Wischik C, Crowther R, Walker J, Klug A (1988): Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau. Proc Natl Acad Sci USA 85:4051-4055.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4051-4055
-
-
Goedert, M.1
Wischik, C.2
Crowther, R.3
Walker, J.4
Klug, A.5
-
13
-
-
0025772021
-
Molecular characterization of microtubule-associated proteins tau and MAP2
-
Goedert M, Crowther RA, Garner CC (1991): Molecular characterization of microtubule-associated proteins tau and MAP2. Trends Neurosci 14:193-199.
-
(1991)
Trends Neurosci
, vol.14
, pp. 193-199
-
-
Goedert, M.1
Crowther, R.A.2
Garner, C.C.3
-
15
-
-
0026595846
-
Tau protein of Alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms
-
Goedert M, Spillantini MG, Cairns NJ, Crowther RA (1992b): Tau protein of Alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms. Neuron 8:159-168.
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
16
-
-
0027214404
-
Phosphoprotein phosphatase activities in Alzheimer disease brain
-
Gong CX, Singh TJ, Grundke-Iqbal I, Iqbal K (1993): Phosphoprotein phosphatase activities in Alzheimer disease brain. J Neurochem 61:921-927.
-
(1993)
J Neurochem
, vol.61
, pp. 921-927
-
-
Gong, C.X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
17
-
-
0028044722
-
Alzheimer's disease abnormally phosphorylated tau is dephosphorylated by protein phosphatase 2B (calcineurin)
-
Gong CX, Singh TJ, Grundke-Iqbal I, Iqbal K (1994a): Alzheimer's disease abnormally phosphorylated tau is dephosphorylated by protein phosphatase 2B (calcineurin). J Neurochem 62:803-806.
-
(1994)
J Neurochem
, vol.62
, pp. 803-806
-
-
Gong, C.X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
18
-
-
0028064431
-
Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase 2A
-
Gong CX, Grundke-Iqbal I, Iqbal K (1994b): Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase 2A. Neuroscience 61:765-772.
-
(1994)
Neuroscience
, vol.61
, pp. 765-772
-
-
Gong, C.X.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
19
-
-
0028350740
-
Dephosphorylation of microtubule-associated protein tau by protein phos-phatase-1 and -2C and its implications in Alzheimer disease
-
Gong CX, Grundke-Iqbal I, Damuni Z, Iqbal K (1994c): Dephosphorylation of microtubule-associated protein tau by protein phos-phatase-1 and -2C and its implications in Alzheimer disease. FEBS Lett 341:94-98.
-
(1994)
FEBS Lett
, vol.341
, pp. 94-98
-
-
Gong, C.X.1
Grundke-Iqbal, I.2
Damuni, Z.3
Iqbal, K.4
-
20
-
-
0021842984
-
Dephosphorylation of microtubule-associated protein 2, τ factor, and tubulin by calcineurin
-
Goto S, Yamamoto H, Fukunaga K, Iwasa T, Matsukado Y, Miyamoto E (1985): Dephosphorylation of microtubule-associated protein 2, τ factor, and tubulin by calcineurin. J Neurochem 45:276-283.
-
(1985)
J Neurochem
, vol.45
, pp. 276-283
-
-
Goto, S.1
Yamamoto, H.2
Fukunaga, K.3
Iwasa, T.4
Matsukado, Y.5
Miyamoto, E.6
-
21
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I, Iqbal K, Tung Y-C, Quinlan M, Wisniewski HM, Binder LI (1986): Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci USA 83:4913-4917.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.-C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
22
-
-
0024461007
-
Tau protein becomes long and stiff upon phosphorylation: Correlation between paracrystalline structure and degree of phosphorylation
-
Hagestedt T, Lichtenberg B, Wille H, Mandelkow E-M, Mandelkow E (1989): Tau protein becomes long and stiff upon phosphorylation: Correlation between paracrystalline structure and degree of phosphorylation. J Cell Biol 109:1643-1651.
-
(1989)
J Cell Biol
, vol.109
, pp. 1643-1651
-
-
Hagestedt, T.1
Lichtenberg, B.2
Wille, H.3
Mandelkow, E.-M.4
Mandelkow, E.5
-
23
-
-
0028147210
-
Alzheimer's disease. A glycation connection
-
Harrington CR, Colaco CA (1994): Alzheimer's disease. A glycation connection. Nature 370:247-248.
-
(1994)
Nature
, vol.370
, pp. 247-248
-
-
Harrington, C.R.1
Colaco, C.A.2
-
24
-
-
0027404098
-
Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices
-
Harris KA, Oyler GA, Doolittle GM, Vincent I, Lehman RAW, Kincaid RL, Billingsley ML (1993): Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices. Ann Neurol 33:77-87.
-
(1993)
Ann Neurol
, vol.33
, pp. 77-87
-
-
Harris, K.A.1
Oyler, G.A.2
Doolittle, G.M.3
Vincent, I.4
Lehman, R.A.W.5
Kincaid, R.L.6
Billingsley, M.L.7
-
25
-
-
0028361538
-
Alzheimer paired helical filaments: Restoration of the biological activity by dephosphorylation
-
Iqbal K, Zaidi T, Bancher C, Grundke-Iqbal I (1994): Alzheimer paired helical filaments: Restoration of the biological activity by dephosphorylation. FEBS Lett 349:104-108.
-
(1994)
FEBS Lett
, vol.349
, pp. 104-108
-
-
Iqbal, K.1
Zaidi, T.2
Bancher, C.3
Grundke-Iqbal, I.4
-
26
-
-
0026731425
-
Tau protein kinase I converts normal tau protein into A68-like component of paired heical filaments
-
Ishiguro K, Takamatsu M, Tomizawa K, Omori A, Takahashi M, Arioka M, Uchida T, Imahori K (1992): Tau protein kinase I converts normal tau protein into A68-like component of paired heical filaments. J Biol Chem 267:10897-10901.
-
(1992)
J Biol Chem
, vol.267
, pp. 10897-10901
-
-
Ishiguro, K.1
Takamatsu, M.2
Tomizawa, K.3
Omori, A.4
Takahashi, M.5
Arioka, M.6
Uchida, T.7
Imahori, K.8
-
27
-
-
0025852163
-
Structure stability of paired helical filaments requires micro-tubule binding domains of tau: A model for self-association
-
Kiezak-Reding H, Yen S-H (1991): Structure stability of paired helical filaments requires micro-tubule binding domains of tau: A model for self-association. Neuron 6:717-728.
-
(1991)
Neuron
, vol.6
, pp. 717-728
-
-
Kiezak-Reding, H.1
Yen, S.-H.2
-
28
-
-
0024109687
-
Epitopes that span the tau molecule are shared with paired helical filaments
-
Kosik KS, Orecchio LD, Binder L, Trojanowski JQ, Lee VM-Y, Lee G (1988): Epitopes that span the tau molecule are shared with paired helical filaments. Neuron 1:817-825.
-
(1988)
Neuron
, vol.1
, pp. 817-825
-
-
Kosik, K.S.1
Orecchio, L.D.2
Binder, L.3
Trojanowski, J.Q.4
Lee, V.M.-Y.5
Lee, G.6
-
29
-
-
0023905288
-
The primary structure and heterogeneity of tau protein from mouse brain
-
Lee G, Cowan N, Kirschner M (1988): The primary structure and heterogeneity of tau protein from mouse brain. Science 239:285-288.
-
(1988)
Science
, vol.239
, pp. 285-288
-
-
Lee, G.1
Cowan, N.2
Kirschner, M.3
-
30
-
-
0027087170
-
Brain proline-directed protein kinase is a neurofilament kinase which displays high sequence homology to p34cdc2
-
Lew J, Winkfein RJ, Paudel HK, Wang JH (1992): Brain proline-directed protein kinase is a neurofilament kinase which displays high sequence homology to p34cdc2. J Biol Chem 267:25922-25926.
-
(1992)
J Biol Chem
, vol.267
, pp. 25922-25926
-
-
Lew, J.1
Winkfein, R.J.2
Paudel, H.K.3
Wang, J.H.4
-
31
-
-
0027335781
-
P44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippcampal neurons
-
Lu Q, Soria JP, Wood JG (1993): p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippcampal neurons. J Neurosci Res 35:439-444.
-
(1993)
J Neurosci Res
, vol.35
, pp. 439-444
-
-
Lu, Q.1
Soria, J.P.2
Wood, J.G.3
-
32
-
-
0027945346
-
Freshly extracted, biopsy derived adult human brain tau is phosphorylated at many of the same sites as paired helical filament tau in Alzheimer's disease
-
Matsuo ES, Shin R-Y, Billingsley ML, Van de Voorde A, O'Connor M, Lee VM-Y (1994): Freshly extracted, biopsy derived adult human brain tau is phosphorylated at many of the same sites as paired helical filament tau in Alzheimer's disease. Neuron 13:989-1002.
-
(1994)
Neuron
, vol.13
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.-Y.2
Billingsley, M.L.3
Van de Voorde, A.4
O'Connor, M.5
Lee, V.M.-Y.6
-
34
-
-
0023034195
-
Reversible assembly purification of microtubules without assembly-promoting and further purification of tubulin, microtubule-associated proteins, and MAP fragments
-
Vallee RB (1986): Reversible assembly purification of microtubules without assembly-promoting and further purification of tubulin, microtubule-associated proteins, and MAP fragments. Methods Enzymol 134:89-104.
-
(1986)
Methods Enzymol
, vol.134
, pp. 89-104
-
-
Vallee, R.B.1
-
35
-
-
0026521716
-
A protein kinase associated with paired helical filaments in Alzheimer's disease
-
Vincent IJ, Davies P (1992): A protein kinase associated with paired helical filaments in Alzheimer's disease. Proc Natl Acad Sci USA 89:2878-2882.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2878-2882
-
-
Vincent, I.J.1
Davies, P.2
-
36
-
-
0026564431
-
Proline-directed phosphorylation of human tau protein
-
Vulliet R, Halloran SM, Braun RK, Smith AJ, Lee G (1992): Proline-directed phosphorylation of human tau protein. J Biol Chem 267:22570-22574.
-
(1992)
J Biol Chem
, vol.267
, pp. 22570-22574
-
-
Vulliet, R.1
Halloran, S.M.2
Braun, R.K.3
Smith, A.J.4
Lee, G.5
-
37
-
-
0023933407
-
Dephosphorylation of microtubule proteins by brain protein phosphatases 1 and 2A, and its effect on microtubule stability
-
Yamamoto H, Saitoh Y, Fukunaga K, Nishimura H, Miyamoto E (1988): Dephosphorylation of microtubule proteins by brain protein phosphatases 1 and 2A, and its effect on microtubule stability. J Neurochem 50:1614-1623.
-
(1988)
J Neurochem
, vol.50
, pp. 1614-1623
-
-
Yamamoto, H.1
Saitoh, Y.2
Fukunaga, K.3
Nishimura, H.4
Miyamoto, E.5
-
38
-
-
0025472051
-
Dephosphorylation of T factor by protein phosphatase 2A in synaptosomal cytosol fractions, and inhibition by aluminum
-
Yamamoto H, Saitoh Y, Yasugawa S, Miyamoto E (1990). Dephosphorylation of T factor by protein phosphatase 2A in synaptosomal cytosol fractions, and inhibition by aluminum. J Neurochem 55:683-690.
-
(1990)
J Neurochem
, vol.55
, pp. 683-690
-
-
Yamamoto, H.1
Saitoh, Y.2
Yasugawa, S.3
Miyamoto, E.4
-
39
-
-
0027237861
-
Tau in paired helical filaments is functionally distinct from fetal tau: Assembly incompetence of paired helical filament tau
-
Yoshida H, Ihara Y (1993): Tau in paired helical filaments is functionally distinct from fetal tau: Assembly incompetence of paired helical filament tau. J Neurochem 61:1183-1186.
-
(1993)
J Neurochem
, vol.61
, pp. 1183-1186
-
-
Yoshida, H.1
Ihara, Y.2
|