Fluorine-18-fluorodeoxyglucose PET to determine regional cerebral glucose utilization: A re-examination

Journal of Nuclear Medicine

Volumn 37, Issue 2, 1996, Pages 394-399

  Schmidt, Kathleen C ^a   Lucignani, Giovanni ^b   Sokoloff, Louis ^b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ARTICLE; BRAIN SCINTISCANNING; GLUCOSE BRAIN LEVEL; GLUCOSE UTILIZATION; HUMAN; MATHEMATICAL ANALYSIS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RELIABILITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

BRAIN; DEOXYGLUCOSE; FLUORINE RADIOISOTOPES; FLUORODEOXYGLUCOSE F18; GLUCOSE; HUMANS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0029874882     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. 18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man Circ Res 1979,44 127-137
2. 18F]2-fluoro2-deoxy-D-glucose validation of method. Ann Neurol 1979;6.371-388.
3. 18F]2-fluoro-2-deoxy-D-glucose a comparison of different analytical methods J Cereb Blood Flow Metab 1987,7:161-172
4. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure and normal values in the conscious and anesthetized albino rat. J Neurochem 1977,28.897-916
5. Huang SC, Phelps ME, Hoffman EJ, Sideris K, Selin CJ, Kuhl DE Noninvasive determination of local cerebral metabolic rate of glucose in man Am J Physiol 1980;238:E69-E82.
6. Patlak C, Blasberg R. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations. J Cereb Blood Flow Metab 1985,5.584-590.
7. Patlak C, Blasberg R, Fenstermacher J. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983;3.1-7
8. Cunningham VJ, Jones T Spectral analysis of dynamic PET studies. J Cereb Blood Flow Metab 1993;13:15-23
9. 18F]fluorodeoxyglucose: theory, implementation and optimization procedures. J Cereb Blood Flow Metab 1994;14:406-422
10. Landau WM, Freygang WH, Rowland LP, Sokoloff L, Kety SS The local circulation of the living brain, values in the unanesthetized and anesthetized cat. Trans Am Neurol Assoc 1955,80:125-129.
11. Schmidt K, Mies G, Sokoloff L. Model of kinetic behavior of deoxyglucose in heterogeneous tissues in brain, a reinterpretation of the significance of parameters fitted to homogeneous tissue models J Cereb Blood Flow Metab 1991,11.10-24
12. 18F]fluorodeoxyglucose. J Cereb Blood Flow Metab 1990,10.180-189.
13. 18F]fluorodeoxyglucose method. J Cereb Blood Flow Metab 1992;12.823-834
14. 18F]FDG and PET in heterogeneous tissues: theoretical considerations and practical procedure J Nucl Med 1993:34:360-369.
15. Mori K, Schmidt K, Jay T, et al Optimal duration of experimental period in measurement of local cerebral glucose utilization with the deoxyglucose method J Neurochem 1990,54:307-319
16. Gjedde A, Wienhard K, Heiss W-D, et al. Comparative regional analysis of 2-fluorodeoxyglucose and methylglucose uptake in brain of four stroke patients With special reference to the regional estimation of the lumped constant. J Cereb Blood Flow Metab 1985;5:163-178
17. 18F]2-fluoro-2-deoxy-D-glucose: a critical appraisal of optimization procedures. J Cereb Blood Flow Metab 1985;5:115-125.
18. 14C]glucose in plasma and brain, influence on rate of glucose utilization determined with deoxyglucose method in rat brain. J Cereb Blood Flow Metab 1993,13:315-327.
19. Kuwabara H, Gjedde A Measurements of glucose phosphorylation with FDG and PET are not reduced by dephosphorylation of FDG-6-phosphate. J Nucl Med 1991,32 692-698.
20. Hawkins RA, Miller AL Loss of radioactive 2-deoxy-D-glucose-6-phosphate from brains of conscious rats: implications for quantitative autoradiographic determination of regional glucose utilization. Neuroscience 1978,3 251-258.
21. Hawkins RA, Miller AL Deoxyglucose-6-phosphate stability in vivo and the deoxyglucose method. J Neurochem 1987;49 1941-1960.
22. Huang M-T, Veech RL. The quantitative determination of the in vivo dephosphorylation of glucose 6-phosphate in rat brain. J Biol Chem 1982;257 11358-11363.
23. 14C]deoxyglucose-6-phosphate in brain in vivo J Neurochem 1985,44 567-573.
24. Sacks W, Sacks S, Fleischer A A comparison of the cerebral uptake and metabolism of labeled glucose and deoxyglucose in vivo in rats. Neurochem Res 1983;8:661-685.
25. Pelligrino DA, Miletich SC, Albrecht RS Time course of radiolabeled 2-deoxy-D-glucose 6-phosphate turnover in cerebral cortex of goats Am J Physiol 1987;252 (Regulatory Integrative Comp. Physiol. 21):R276-R283.
26. Nelson T, Lucignani G, Atlas S, Crane AM, Dienel GA, Sokoloff L. Re-examination of glucose-6-phosphatase activity in the brain in vivo: no evidence for a futile cycle. Science 1985;229:60-62
27. Nelson T, Lucignani G, Goochee J, Crane AM, Sokoloff L Invalidity of criticisms of the deoxyglucose method based on alleged glucose-6-phosphatase activity in brain. J Neurochem 1986;46.905-919.
28. Nelson T, Dienel GA, Mori K, Cruz NF, Sokoloff L Deoxyglucose-6-phosphate stability in vivo and the deoxyglucose method: response to comments of Hawkins and Miller. J Neurochem 1987,49.949-1960.
29. 14C-labeled metabolites J Biol Chem 1988,263.19697-19708.
30. Hers HG. Le Métabolisme du Fructose Brussels. Editions Arscia, 1957:102
31. Sokoloff L The radioactive deoxyglucose method. Theory, procedure and applications for the measurement of local glucose utilization in the central nervous system. In: Agranoff BW, Aprison MH, eds. Advances in Neurochemistry, vol. 4. New York. Plenum; 1982:1-82
32. Fishman RS, Karnovsky ML Apparent absence of a translocase in the cerebral glucose-6-phosphatase system J Neurochem 1986,46:371-378.
33. Schuier F, Orzi F, Suda S, Lucignani G, Kennedy C, Sokoloff L Influence of plasma glucose concentration on lumped constant of the deoxyglucose method: effects of hyperglycemia in the rat. J Cereb Blood Flow Metab 1990;10:765-773.
34. Suda S, Shinohara M, Miyaoka M, Lucignani G, Kennedy C, Sokoloff L The lumped constant of the deoxyglucose method in hypoglycemia: effects of moderate hypoglycemia on local cerebral glucose utilization in the rat J Cereb Blood Flow Metab 1990,10.499-509.
35. Dienel GA, Cruz NF, Mori K, Holden J, Sokoloff L. Direct measurement of the λ of the lumped constant of the deoxyglucose method in rat brain: determination of λ and lumped constant from tissue glucose concentration or equilibrium tissue: plasma distribution ratio for methylglucose. J Cereb Blood Flow Metab 1991,11:25-34
36. Dienel GA, Nakanishi H, Cruz NF, Sokoloff L Determination of local brain glucose concentration from the brain, plasma methylglucose distribution ratio, influence of glucose utilization rate [Abstract]. J Cereb Blood Flow Metab 1991,11(suppl 2).S581.
37. 11C]deoxyglucose. J Cereb Blood Flow Metab 1985;5:179-192.
38. Brooks RA, Hatazawa J, DiChiro G, Larson SM, Fishbein DS. Human cerebral glucose metabolism determined by positron emission tomography a revisit. J Cereb Blood Flow Metab 1987;7:427-432
39. Jagust WJ, Budinger TF, Huesman RH, Friedland RP, Mazoyer BM, Knittel BL. Methodologie factors affecting PET measurements of cerebral glucose metabolism. J Nucl Med 1986;27.1358-1361.
40. DiChiro G, Brooks RA. PET quantitation blessing and curse [Editorial]. J Nucl Med 1988;29:1603-1604
41. Kennedy C, Gillin JC, Mendelson W, et al. Local cerebral glucose utilization in nonrapid eye movement sleep Nature (London) 1982,297:325-327.
42. Heiss W-D, Pawlik G, Herholz K, Wagner R, Wienhard K. Regional cerebral glucose metabolism in man during wakefulness, sleep and dreaming. Brain Res 1985;327.32-366.