Peroxynitrite reduction of calmodulin stimulation of neuronal nitric oxide synthase

Chemical Research in Toxicology

Volumn 9, Issue 2, 1996, Pages 484-491

  Hühmer, Andreas F R ^a   Gerber, Nancy Counts ^b   Ortiz De Montellano, Paul R ^a,b   Schöneich, Christian ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CALMODULIN; CYTOCHROME C; METHIONINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; SUPEROXIDE; TYROSINE;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN TISSUE; CARBOXY TERMINAL SEQUENCE; CATTLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME METABOLISM; NITRATION; NONHUMAN; OXIDATION; PROTEIN PURIFICATION; REDUCTION;

BINDING, COMPETITIVE; CALMODULIN; CYTOCHROME C GROUP; DOWN-REGULATION; FEEDBACK; KINETICS; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDES;

EID: 0029874821     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950152l     Document Type: Article

References (46)

1. James, P., Vorherr, T., and Carafoli, E. (1995) Calmodulin-binding domains: just two faced or multi-faceted? Trends Biochem. Sci. 20, 38-42.
2. Abu-Soud, H. M., and Stuehr, D J. (1993) Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer. Proc. Natl. Acad. Sci. U.S.A. 90, 10769-10772.
3. Abu-Soud, H. M., Yoho, L. L., and Stuehr, D. J. (1994) Calmodulin controls neuronal nitric-oxide synthase by a dual mechanism: activation of intra- and interdomain electron transfer. J Biol. Chem. 269, 32047-32050.
4. Pou, S., Pou, W. S., Bredt, D. S., Snyder, S. H., and Rosen, G. M. (1992) Generation of superoxide by purified brain nitric oxide synthase. J. Biol. Chem. 267, 24173-24176.
5. Mayer, B., Heinzel, B., Klatt, P., John, M., Schmidt, K., and Böhme, E. (1992) Nitric oxide synthase-catalyzed activation of oxygen and reduction of cytochromes: reaction mechanisms and possible physiological implications. J. Cardiovasc. Pharmacol. 12, 54-56.
6. Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., and Freeman, B. A. (1990) Apparent hydroxy radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U.S.A. 87, 1620-1624.
7. -. Free Radical Res. Commun. 18, 195-199.
8. Pryor, W. A., and Squadrito, G. L. (1995) The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am. J Physiol. 268, L699-L722.
9. Radi, R., Beckman, J. S., Bush, K. M., and Freeman B. A. (1991) Peroxynitrite oxidation of sulfhydryls. J. Biol. Chem. 266, 4244-4250.
10. Pryor, W. A., Jin, X., and Squadrito, G. L. (1994) One- and two-electron oxidations of methionine by peroxynitrite. Proc. Natl Acad. Sci. U.S.A. 91, 11173-11177.
11. Ischiropoulos, H., Zhu, L., Chen, J., Tsai, M., Martin, J. C., Smith, C. D., and Beckmann, J. S. (1992) Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch. Biochem Biophys. 298, 431-437.
12. Van der Vliet, A., O'Neill, C. A., Halliwell, B., Cross, C. E., and Kaur, H. (1994) Aromatic hydroxytation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite. FEBS Lett. 339, 89-92
13. Radi, R., Beckman, J. S., Bush, K. M., and Freeman B. A. (1991) Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288, 481-487.
14. Rengasamy, A , and Johns, R A. (1993) Inhibition of nitric oxide synthase by a superoxide generating system. J. Pharmacol Exp. Ther. 267, 1024-1027.
15. 2+-ATPase and of bovine brain cyclic nucleotide phosphodiesterase by chemically modified calmodulin. Eur. J. Biochem. 170, 35-42.
16. Gerber, N. C., and Ortiz de Montellano, P. R (1995) Neuronal nitric oxide synthase. Expression in Escherichia coli, irreversible inhibition by phenyldiazene, and active site topology J. Biol. Chem. 270, 17791-17796.
17. Pryor, W. A., Cueto, R., Jin, X., Koppenol, W. H., Ngu-Schwemlein, M., Squadrito, G. L., Uppu, P. L., and Uppu, R. M. (1995) A practical method for preparing peroxynitrite solutions of low ionic strength and free of hydrogen peroxide. Free Radicals Biol Med. 18, 75-83.
18. Hughes, M. N., and Nicklin, H. G. (1968) The chemistry of pernitrites. Part I. Kinetics of decomposition of pernitrous acid. J. Chem. Soc. A 450-456.
19. 2+-induced hydrophobic site on calmodulin: application for purification of calmodulin by phenyl-Sepharose affinity chromatography. Biochem Biophys. Res. Commun. 104, 830-836.
20. Berkowitz, S. A. (1987) Linear multidimensional liquid chromatography in the preparative scale purification of calmnodulin from brain extract. Anal. Biochem. 164, 254-268.
21. Klee, C. B. (1980) Calmodulin: Structure-function relationships. In Calcium and Cell Function (Cheung, W. Y., Ed.) Vol. I, pp 59-74, Academic Press, New York.
22. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
23. Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354.
24. Murphy, M. E., and Noack, E. (1994) Nitric oxide assay using hemoglobin method. Methods Enzymol. 233, 241-255.
25. McMillan, K., and Masters, B. S S (1995) Prokaryotic expression of the heme- and flavin-binding domain of the rat neuronal nitric oxide synthase as distinct polypeptides: identification of the heme-binding proximal thiolate ligand cysteine-415. Biochemistry 34, 3683-3693.
26. 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem. J. 281, 627-630.
27. Zhang, M., and Vogel, J. (1994) The calmodulin-binding domain of caldesmon binds to calmodulin in an α-helical conformation. Biochemistry 33, 1163-1171.
28. Zhang, M., Li, M., Wang, J. H., and Vogel, J. (1994) The effect of Met-Leu mutations on calmodulin's ability to activate cyclic nucleotide phosphodiesterase. J. Biol. Chem. 269, 15546-15552.
29. Crow, J. P., Spruell, C., Chen, J., Gunn, C., Ischiropoulos, H , Tsai, M., Smith, C. D., Radi, R., Koppenol, W. H., and Beckmann, J. S. (1994) On the pH-dependent yield of hydroxyl radical products from peroxynitrite. Free Radicals Biol. Med. 16, 331-338.
30. Koppenol, W. H., Moreno, J. J., Pyror, W. A., Ischiropoulos, H., and Beckman, J. S. (1992) Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide. Chem. Res. Toxicol. 5, 834-842.
31. Chattopadhyaya, R., Meador, W. E., Means, A. R., and Quiocho, F. A. (1992) Calmodulin structure refined at 1.7 Å resolution. J. Mol Biol. 28, 1177-1192.
32. Wilson, G. S., Swanson, D. D., Klug, J. T., Glass, R. S., Ryan, M. D., and Musker, W. K. (1979) Electrochemical oxidation of some mesocyclic dithioethers and related compounds. J. Am. Chem. Soc. 101, 1040-1042.
33. 2O J. Inorg. Biochem 55, 87-99.
34. Babu, Y. S., Sack, J. S., Greenbough, T. J., Bugg, C. E., Means, A. R., and Cook, W. J. (1985) Three-dimensional structure of calmodulin. Nature 315, 37-40.
35. Meador, W. E., Means, A. R., and Quiocho, F. A. (1992) Target enzyme recognition by calmodulin: 2.4 Å structure of a calmodulin-peptide complex. Science 257, 1251-1255.
36. Meador, W. E., Means, A. R., and Quiocho, F. A. (1993) Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structure. Science 262, 1718-1721.
37. Babu, Y. S., Bugg, C. E., and Cook, W. J. (1988) Structure of calmodulin refined at 2.2 Å resolution. J. Mol. Biol. 204, 191-204.
38. Ikura, M , Clore, G. M., Gronenborn, A. M., Zhu, G., Klee, C. B., and Bax, A. (1992) Solution structure of calmodulin-target peptide complex by multidimensional NMR. Science 256, 632-638.
39. Persechini, A., McMillan, K., and Leakey, P. (1994) Activation of myosin light chain kinase and nitric oxide synthase activities by calmodulin fragments. J. Biol. Chem. 269, 16148-16154.
40. Di Maseio, P., Bechara, E. J H., Medeiros, M. H. G., Briviba, K., and Sies, H. (1994) Singlet molecular oxygen production in the reaction of peroxynitrite with hydrogen peroxide. FEBS Lett. 355, 287-289.
41. Ischiropoulos, H., Zhu, L., and Beckman, J. S. (1992) Peroxynitrite formation from macrophage-derived nitric oxide. Arch. Biochem. Biophys. 298, 446-451.
42. Smith, C. D., Carney, J. M., Tatsumo, T., Stadtman, E. R., Floyd, R. A., and Markesbery, W. A. (1992) Protein oxidation in aging brain. Ann. N.Y. Acad. Sci. 663, 110-119.
43. Matheis, G., Sherman, M. P., Buckberg, G. D., Haybron, D. M., Young, H. H., and Ignarro, L. J. (1992) Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury. Am. J. Physiol. 262, H616-H620
44. Zweier, J. L., Wang, P., and Kuppusamy, P. (1995) Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy. J. Biol. Chem. 270, 304-307.
45. Kukreja, R. C., and Hess, M. L. (1992) The oxygen free radical system: from equations through membrane-protein interactions to cardiovascular injury and protection. Cardiovasc. Res. 26, 641-655
46. Fliss, H., and Docherty, G. (1987) Oxidation of methionine in proteins of isolated rat heart myocytes and tissue slices by neutrophil-generated oxygen free radicals. Develop. Cardiovasc. Med. 67, 85-98.