Opioid antagonists in the treatment of alcohol dependence: Clinical efficacy and prevention of relapse

Alcohol and Alcoholism

Volumn 31, Issue SUPPL. 1, 1996, Pages 77-81

  O'Malley, Stephanie S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; NALMEFENE; NALTREXONE; OPIATE ANTAGONIST; NARCOTIC ANTAGONIST;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOLISM; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CLINICAL TRIAL; CONFERENCE PAPER; DISEASE SEVERITY; DRINKING BEHAVIOR; DRUG EFFICACY; HUMAN; META ANALYSIS; PRIORITY JOURNAL; REINFORCEMENT; RELAPSE; SELF REPORT; CONTROLLED CLINICAL TRIAL; PSYCHOLOGICAL ASPECT; RECURRENT DISEASE; REVIEW;

ALCOHOLISM; CONTROLLED CLINICAL TRIALS; HUMANS; NALTREXONE; NARCOTIC ANTAGONISTS; RECURRENCE;

EID: 0029874321     PISSN: 07350414     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.alcalc.a008223     Document Type: Conference Paper

References (20)

1. Bohn, M. J., Kranzler, H. R., Beazoglou, D. and Staehler, B. A. (1994) Naltrexone and brief counseling to reduce heavy drinking: results of a small clinical trial. American Journal on Addictions 3, 91-99.
2. Croop, R. S., Labriola, D. F., Wroblewski, J. M. and Nibbelink, D. W. (1995) A multicenter safety study of naltrexone as adjunctive pharmacotherapy for individuals with alcoholism. Presented at the annual meeting of the American Psychiatric Association, May 20-25, 1995, Miami, Florida.
3. Ehrman, R., Ternes, J., O'Brien, C. P. and McLellan, A. T. (1992) Conditioned tolerance in human opiate addicts. Psychopharmacology 108, 218-224.
4. Engle, K. B. and Williams, T. K. (1972) Effect of an ounce of vodka on alcoholics' desire for alcohol. Quarterly Journal of Studies of Alcohol 33, 1099-1105.
5. Hilton, M. E. (1987) Drinking patterns and drinking problems in 1984: results from a general population survey. Alcoholism: Clinical and Experimental Research 11, 167-175.
6. Ludwig, A. M., Wikler, A. and Stark, L. H. (1974) The first drink: psychobiological aspects of craving. Archives of General Psychiatry 30, 539-547.
7. Mason, B. J., Ritvo, E. C., Morgan, R. O., Salvato, F. R., Goldberg, G., Welch, B. and Mantero-Atienza, E. (1994) A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence. Alcoholism: Clinical and Experimental Research 18, 1162-1167.
8. Meyer, M. C., Straughn, A. B., Lo, M.-W., Schary, W. L. and Whitney, C. C. (1984) Bioequivalence, dose-proportionality, and pharmacokinetics of naltrexone after oral administration. Journal of Clinical Psychiatry 45, 15-19.
9. Meyer, R. E. and Kranzler, H. R. (1988) Alcoholism: clinical implications of recent research. Journal of Clinical Psychiatry 49 (Suppl. 9), 8-12.
10. O'Malley, S. S. (1995) Strategies to maximize the efficacy of naltrexone for alcohol dependence. In Integrating Behavioral Therapies with Medications in the Treatment of Drug Dependence, Onken, L. S., Blaine, J. D. and Boren, J. J. eds, pp. 53-64. National Institute of Drug Abuse Monograph 150, NIH Publication No. 95-3899; National Institutes of Health, Bethesda.
11. O'Malley, S. S., Jaffe, A. J., Chang, G., Schottenfeld, R. S., Meyer, R. E. and Rounsaville, B. (1992) Naltrexone and coping skills therapy for alcohol dependence: a controlled study. Archives of General Psychiatry 49, 881-887.
12. O'Malley, S. S., Jaffe, A. J., Rode, S. and Rounsaville, B. J. (1996) Experience of a 'slip' among alcoholics treated with naltrexone or placebo. American Journal of Psychiatry 153, 281-283.
13. Robinson, T. E. and Berridge, K. C. (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Research Reviews 18, 247-291.
14. Siegel, P. Z., Brackbill, R. M., Frazier, E. L., Mariolis, P., Sanderson, L. M. and Waller, M. N. (1991) Behavioral risk factor surveillance, 1985-1990. Morbidity and Mortality Weekly Report 40, (No. SS-4), 1-23.
15. Swift, R. M., Whelihan, W., Kuznetsov, O., Buongiorno, G. and Hsuing, H. (1994) Naltrexone-induced alterations in human ethanol intoxication. American Journal of Psychiatry 151, 1463-1467.
16. Verebey, K., Volavka, J., Mulé, S. J. and Resnick, R. B. (1976) Naltrexone: disposition, metabolism, and effects after acute and chronic dosing. Clinical Pharmacology and Therapeutics 20, 315-328.
17. Volpicelli, J. R. (1987) Uncontrollable events and alcohol drinking. British Journal of Addiction 82, 381-392.
18. Volpicelli, J. R., O'Brien, C. P., Alterman, A. I. and Hayashida, M. (1990) Naltrexone and the treatment of alcohol dependence: initial observations. In Opioids, Bulimia, and Alcohol Abuse and Alcoholism, Reid, L. D. ed., pp. 195-214. Springer-Verlag, New York.
19. Volpicelli, J. R., Alterman, A. I., Hayashida, M. and O'Brien, C. P. (1992) Naltrexone in the treatment of alcohol dependence. Archives of General Psychiatry 49, 876-880.
20. Volpicelli, J. R., Watson, N. T., King, A. C. and Sherman, C. E. (1995) Effect of naltrexone on alcohol 'high' in alcoholics. American Journal of Psychiatry 152, 613-615.