Graft-versus-leukaemia activity can be predicted by natural cytotoxicity against leukaemia cells

British Journal of Haematology

Volumn 93, Issue 2, 1996, Pages 412-420

  Glass, Bertram ^a,b   Uharek, Lutz ^a   Zeis, Matthias ^a   Loeffler, Helmut ^a   Mueller Ruchholtz, Wolfgang ^a   Gassmann, Winifried ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

animal model; bone marrow transplantation; graft versus host disease; graft versus leukemia effect; natural killer cells

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; LEUKEMIA; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 0029874166     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.4941035.x     Document Type: Article

References (35)

1. Aizawa, S. & Sado, T. (1991) Graft-versus-leukemia effect in MHC-compatible and -incompatible allogeneic bone marrow transplantation of radiation-induced, leukemia-bearing mice. Transplantation, 52, 885-880.
2. Blaise, U., Olive, D., Stoppa, A.M., Viens, P., Pourreau, C., Lopez, M., Attal, M., Jasmin, C., Monges, G., Mawas, C., Mannoni, P., Palmer, P., Franks, C., Philip, T. & Maraninchi, D. (1990) Hematologic and immunologic effects of the systemic administration of recombinant interleukin-2 after autologous bone marrow transplantation. Blood, 76, 1092-1097.
3. Bortin, M.M., Truitt, R.L., Rimm, A.A. & Bach, F.H. (1979) Graft-versus-leukaemia reactivity induced by alloimmunisation without augmentation of graft-versus-host reactivity. Nature, 281, 490-491.
4. + T lymphocytes for prevention of graft-versus-host disease after allogeneic bone marrow transplantation. Blood, 76, 418-423.
5. Charak, B.S., Brynes, R.K., Groshen, S., Chen, S.C. & Mazumder, A. (1990) Bone marrow transplantation with interleukin-2-activated bone marrow followed by interleukin-2 therapy for acute myeloid leukemia in mice. Blood, 76, 2187-2190.
6. Christiansen, F.T., Witt, C.S., Ciccone, E., Townend, D., Pende, D., Viale, D., Abraham, L.J., Dawkins, R.I, & Moretta, L. (1993) Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: ancestral haplotypes encode particular NK-defined haplotypes. Journal of Experimental Medicine, 178, 1033-1039.
7. Ferrara, J.L. & Deeg, H.J. (1991) Graft-versus-host disease. New England Journal of Medicine, 324, 667-672.
8. Gale, R.P. & Champlin, R.E. (1984) How does bone-marrow transplantation cure leukaemia? Lancet, ii, 28-30.
9. Glass, B., Uharek, L., Gaska, T., Gassmann, W., Löffler, H. & Mueller-Ruchholtz, W. (1993) The influence of graft-versus-host reactivity, lymphocyte depletion, and cell dose on allogeneic bone marrow engraftment. Bone Marrow Transplantation, 12, (Suppl. 3), 41-47.
10. Glass, B., Uharek, L., Gassmann, W., Focks, B., Bolouri, H., Löffler, H. & Müller-Ruchholtz, W. (1992) Graft-versus-leukemia activity after bone marrow transplantation does not require graft-versus-host disease. Annals of Hematology, 64, 255-259.
11. Hauch, M., Gazzola, M.V., Small, T., Bordignon, C., Barnett, L., Cunningham, I., Castro Malaspinsa, H., O'Reilly, R.J. & Keever, C.A. (1990) Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia. Blood. 75, 2250-2262.
12. 51Cr-release cytotoxicity of lymphocytes immune to murine sarcoma virus. Journal of the National Cancer Institute, 53, 1103-1111.
13. Hercend, T., Takvorian, T., Nowill, A., Tantravahi, R., Moingeon, P., Anderson, K.C., Murray, C., Bohuon, C., Ythier, A. & Ritz, J. (1986) Characterization of natural killer cells with antileukemia activity following allogeneic bone marrow transplantation. Blood, 67, 722-728.
14. Heslop, H.E., Duncombe, A.S., Reittie, J.E., Bello Fernandez, C., Gottlieb, D.J., Prentice, H.G., Mehta, A.B., Hoffbrand, A.V. & Brenner, M.K. (1991) Interleukin 2 infusion induces haemopoietic growth factors and modifies marrow regeneration after chemotherapy or autologous marrow transplantation. British Journal of Haematology, 77, 237-244.
15. Horowitz, M.M., Gale, R.P., Sondel, P.M., Goldman, J.M., Kersey, J., Kolb, H.J., Rimm, A.A., Ringden, O., Rozman, C., Speck, B., Truitt, R.L., Zwaan, F.E. & Bortin, M.M. (1990) Graft-versus-leukemia reactions after bone marrow transplantation. Blood, 75, 555-562.
16. Johnson, B.D. & Truitt, R.L. (1992) A decrease in graft-vs.-host disease without loss of graft-vs.-leukemia reactivity after MHC-matched bone marrow transplantation by selective depletion of donor NK cells in vivo. Transplantation, 54, 104-112.
17. Jones, R.J., Ambinder, R.F., Piantodosi, S. & Santos, G.W. (1991) Evidence of a graft-versus-lymphoma effect associated with allogeneic bone marrow transplantation. Blood. 77, 649-653.
18. Keever, C.A., Welte, K., Small, T., Levick, J., Sullivan, M., Hauch, M., Evans, R.L. & O'Reilly, R.J. (1987) Interleukin 2-activated killer cells in patients following transplants of soybean lectin-separated and E rosette-depleted bone marrow. Blood, 70, 1893-1903.
19. Kim, K.J., Kannellopoulus-Langevin, C., Mervin, R.M., Sachs, D.H. & Asofsky, R. (1979) Establishment and characterization of Balb/c lymphoma lines with B cell properties. Journal of Immunology, 122, 549-554.
20. O'Kunewick, J.P., Kociban, D.L. & Buffo, M.J. (1990) Comparative effects of various T cell subtypes on GVHD in a murine model for MHC-matched unrelated donor transplant. Bone Marrow Transplantion, 5, 145-152.
21. Ralph, P., Moore, M.A.S.& Nilsson, K. (1976) Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. Journal of Experimental Medicine, 143, 1528-1533.
22. Slavin, S., Weiss, L., Morecki, S. & Weigensberg, M. (1981) Eradication of murine leukemia with histoincompatible marrow grafts in mice conditioned with total lymphoid irradiation. Cancer Immunology and Immunotherapy, 11, 155-161.
23. Soiffer, R.J., Murray, C., Cochran, K., Cameron, C., Wang, E., Schow, P.W., Daley, J.F. & Ritz, J. (1992) Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation. Blood, 79, 517-526.
24. Sosman, J.A., Oettel, K.R., Hank, J.A., Fisch, P. & Sondel, P.M. (1989) Specific recognition of human leukemic cells by allogeneic T cell lines. Transplantation, 48, 486-495.
25. Sosman, J.A. & Sondel, P.M. (1991) The graft versus leukemia effect: possible mechanisms and clinical significance to the biologic therapy of leukemia. Bone Marrow Transplantation, 7, (Suppl. 1), 33-37.
26. Sullivan, K.M., Weiden, P.L., Storb, R., Witherspoon, R.P., Fefer, A., Fisher, L., Buckner, C.D., Anasetti, C., Appelbaum, F.R., Badger, C., Beatty, P., Bensinger, W., Berenson, R., Bigelow, C., Cheever, M.A., Clift, R., Deeg, H.J., Doney, K., Greenberg, P., Hansen, J.A., Hill, R., Loughran, T., Martin, P., Neiman, P., Petersen, F.B., Sanders, J., Singer, J., Stewart, P. & Thomas, E.D. (1989) Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia. Blood, 73, 1720-1728.
27. Sykes, M., Bukhari, Z. & Sachs, D.H. (1989) Graft-versus-leukemia effect using mixed allogeneic bone marrow transplantation. Bone Marrow Transplantation, 4, 465-474.
28. Uharek, L. Glass, B., Gaska, T., Gassmann, W., Loefler, H. & Mueller Ruchholtz, W. (1994) Influence of donor lymphocytes on the incidence of primary graft failure after allogeneic bone marrow transplantation in a murine model. British Journal of Haematology, 88, 79-87.
29. Warner, N.L., Moore, M.A.S. & Metcalf, D. (1969) A transplantable myelomonocytic leukemia in Balb/c mice: cytology, karyotype and muramidase content. Journal of the National Cancer Institute, 43, 963-982.
30. Weiden, P.L., Flournoy, N., Thomas, E.D., Prentice, R., Fefer, A., Buckner, C.D. & Storb, R. (1979) Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts. New England Journal of Medicine, 300, 1068-1073.
31. Weiss, L., Morecki, S., Vitetta, E.S. & Slavin, S. (1983) Suppression and elimination of BCL1 leukemia by allogeneic bone marrow transplantation. Journal of Immunology, 130, 2452-2455.
32. Weiss, L., Weigensberg, M., Morecki, S., Bar, S., Cobbold, S., Waldmann, H. & Slavin, S. (1990) Characterization of effector cells of graft vs leukemia following allogeneic bone marow transplantation in mice inoculated with murine B-cell leukemia. Cancer Immunology and Immunotherapy, 31, 236-242.
33. Welte, K., Keever, C.A., Levick, J., Bonilla, M.A., Merluzzi, V.J., Mertelsmann, R., Evans, R. & O'Reilly, R.J. (1987) Interleukin-2 production and response to interleukin-2 by peripheral blood mononuclear cells from patients after bone marrow transplantation. II. Patients receiving soybean lectin-separated and T cell-depleted bone marrow. Blood. 70, 1595-1605.
34. Yu, Y.Y., Kumar, V. & Bennett, M. (1992) Murine natural killer cells and marrow graft rejection. Annual Reviews of Immunology, 10, 189-213.
35. Zeis, M., Uharek, L., Glass, B., Gaska, T., Steinmann, J., Gassmann, W., Löffler, L. & Müller-Ruchholtz, W. (1995) Allogeneic NK cells as potent antileukemic effector cells after allogeneic bone marrow transplantation in mice. Transplantation, 59, 1734-1756.