Relationship between cell-killing efficiency and number of platinum atoms binding to DNA, RNA, and protein molecules in HeLa cells Treated with cis -diamine (glycolato)platinum(II)

Japanese Journal of Cancer Research

Volumn 87, Issue 2, 1996, Pages 178-183

  Akaboshi, Mitsuhiko ^a   Kawai, Kenichi ^a   Kinashi, Yuko ^a   Masunaga, Shinichiro ^a   Ono, Koji ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

195mPt 254 S; cis diamine(glycolato)platinum(II); HeLa cell; Mean lethal dose; Target volume

Indexed keywords

CISPLATIN; DNA; NEDAPLATIN; PLATINUM; PROTEIN; RNA;

ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DRUG BINDING; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; HELA CELL; HUMAN; HUMAN CELL; ISOTOPE LABELING; LETHAL DOSE; PRIORITY JOURNAL; RNA BINDING; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL SURVIVAL; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; NEOPLASM PROTEINS; ORGANOPLATINUM COMPOUNDS; PLATINUM; RNA, NEOPLASM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029873790     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1996.tb03156.x     Document Type: Article

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