메뉴 건너뛰기




Volumn 58, Issue 4, 1996, Pages 268-272

Casodex (a nonsteroidal antiandrogen) reduces cancellous, endosteal, and periosteal bone formation in estrogen-replete female rats

Author keywords

Anti androgen; Bone formation; Bone resorption; Osteoblast; Osteoclast

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; BICALUTAMIDE; ESTRADIOL; ESTROGEN; ESTRONE; PRASTERONE; TESTOSTERONE;

EID: 0029873398     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900046     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 0018263644 scopus 로고
    • Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male
    • Baran D, Bergfeld M, Teitelbaum S, Avioli L (1978) Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male. Calcif Tissue Res 26:103-106
    • (1978) Calcif Tissue Res , vol.26 , pp. 103-106
    • Baran, D.1    Bergfeld, M.2    Teitelbaum, S.3    Avioli, L.4
  • 3
  • 4
    • 0026750195 scopus 로고
    • Bone and mineral metabolism in aged male rats: Short- and long-term effects of androgen deficiency
    • Vanderschueren D, Van Herck E, Suiker AMH, Visser WJ, Schot LPC, Bouillon R (1992) Bone and mineral metabolism in aged male rats: short- and long-term effects of androgen deficiency. Endocrinology 130:2906-2916
    • (1992) Endocrinology , vol.130 , pp. 2906-2916
    • Vanderschueren, D.1    Van Herck, E.2    Amh, S.3    Visser, W.J.4    Schot, L.P.C.5    Bouillon, R.6
  • 6
    • 0023090570 scopus 로고
    • Bone mineral density in Addison's disease: Evidence for an effect of adrenal androgens on bone mass
    • Devogelaer JP, Crabbe J, Nagant de Deuxchaisnes C (1987) Bone mineral density in Addison's disease: evidence for an effect of adrenal androgens on bone mass. Br Med J 294:798-800
    • (1987) Br Med J , vol.294 , pp. 798-800
    • Devogelaer, J.P.1    Crabbe, J.2    Nagant de Deuxchaisnes, C.3
  • 7
    • 0024214476 scopus 로고
    • Determinants of peak trabecular bone density in women: The role of androgens, estrogens, and exercise
    • Buchanan J, Myers C, Lloyd T, Leuenberger P, Demers L (1988) Determinants of peak trabecular bone density in women: the role of androgens, estrogens, and exercise. J Clin Endocrinol Metab 3:673-679
    • (1988) J Clin Endocrinol Metab , vol.3 , pp. 673-679
    • Buchanan, J.1    Myers, C.2    Lloyd, T.3    Leuenberger, P.4    Demers, L.5
  • 10
    • 0027175622 scopus 로고
    • Flutamide-mediated androgen blockade evokes osteopenia in the female rat
    • Goulding A, Gold E (1993) Flutamide-mediated androgen blockade evokes osteopenia in the female rat. J Bone Miner Res 8:763-769
    • (1993) J Bone Miner Res , vol.8 , pp. 763-769
    • Goulding, A.1    Gold, E.2
  • 11
    • 0028312129 scopus 로고
    • 5α-dihydrotestosterone partially restores cancellous bone volume in osteopenic ovariectomized rats
    • Tobias JH, Gallagher A, Chambers TJ (1994) 5α-dihydrotestosterone partially restores cancellous bone volume in osteopenic ovariectomized rats. Am J Physiol 267:E853-E859
    • (1994) Am J Physiol , vol.267
    • Tobias, J.H.1    Gallagher, A.2    Chambers, T.J.3
  • 13
    • 3142614548 scopus 로고
    • Pharmacological properties and potential clinical utility of ICI 176, 334: A novel, non-steroidal, peripherally selective antiandrogen
    • Motta M, Serio M (eds) Basic and clinical aspects
    • Furr BJA (1988) Pharmacological properties and potential clinical utility of ICI 176, 334: a novel, non-steroidal, peripherally selective antiandrogen. In: Motta M, Serio M (eds) Hormonal aspects of prostatic disease. Basic and clinical aspects. pp 148-161
    • (1988) Hormonal Aspects of Prostatic Disease , pp. 148-161
    • Furr, B.J.A.1
  • 14
    • 0024347320 scopus 로고
    • A possible explanation for the peripheral selectivity of a novel non-steroidal pure antiandrogen. Casodex (ICI 176334)
    • Freeman SN, Mainwaring WIP, Furr BJA (1989) A possible explanation for the peripheral selectivity of a novel non-steroidal pure antiandrogen. Casodex (ICI 176334). Br J Cancer 60:664-668
    • (1989) Br J Cancer , vol.60 , pp. 664-668
    • Freeman, S.N.1    Mainwaring, W.I.P.2    Furr, B.J.A.3
  • 15
    • 0024788019 scopus 로고
    • Casodex (ICI 176 334) - A new, pure, peripherally selective antiandrogen: Preclinical studies
    • Furr BJA (1989) Casodex (ICI 176 334) - a new, pure, peripherally selective antiandrogen: preclinical studies. Horm Res 32:69-76
    • (1989) Horm Res , vol.32 , pp. 69-76
    • Furr, B.J.A.1
  • 16
    • 0020509916 scopus 로고
    • Relationships among surface, volume and thickness of iliac trabecular bone in ageing and in osteoporosis
    • Parfitt AM, Matthews CHE, Villeneuve AR, Kleerekoper M (1983) Relationships among surface, volume and thickness of iliac trabecular bone in ageing and in osteoporosis. J Clin Invest 72:1396-1409
    • (1983) J Clin Invest , vol.72 , pp. 1396-1409
    • Parfitt, A.M.1    Matthews, C.H.E.2    Villeneuve, A.R.3    Kleerekoper, M.4
  • 17
    • 0006736488 scopus 로고
    • Osteoporosis
    • Albright F (1947) Osteoporosis. Ann Int Med 27:861-882
    • (1947) Ann Int Med , vol.27 , pp. 861-882
    • Albright, F.1
  • 18
    • 0021717406 scopus 로고
    • Relative contributions of ageing and estrogen deficiency to postmenopausal bone loss
    • Richelson LS, Heinze HW, Melton LI III, Riggs BL (1984) Relative contributions of ageing and estrogen deficiency to postmenopausal bone loss. N Engl J Med 311:1273-1275
    • (1984) N Engl J Med , vol.311 , pp. 1273-1275
    • Richelson, L.S.1    Heinze, H.W.2    Melton III, L.I.3    Riggs, B.L.4
  • 21
    • 0025881025 scopus 로고
    • High-affinity androgen binding and androgenic regulation of a(1)-procollagen and transforming growth factor-β steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells
    • Benz DJ, Haussler MR, Thomas MA, Speelman B, Komm BS (1991) High-affinity androgen binding and androgenic regulation of a(1)-procollagen and transforming growth factor-β steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells. Endocrinology 128:2723-2730
    • (1991) Endocrinology , vol.128 , pp. 2723-2730
    • Benz, D.J.1    Haussler, M.R.2    Thomas, M.A.3    Speelman, B.4    Komm, B.S.5
  • 23
    • 0020335470 scopus 로고
    • Pathophysiological mechanism of estrogen effect on bone metabolism: Dose-response relationship in early postmenopausal women
    • Christiansen C, Christiansen MS, Larsen N-E, Transbol I (1982) Pathophysiological mechanism of estrogen effect on bone metabolism: dose-response relationship in early postmenopausal women. J Clin Endocrinol Metab 55:1124-1130
    • (1982) J Clin Endocrinol Metab , vol.55 , pp. 1124-1130
    • Christiansen, C.1    Christiansen, M.S.2    Larsen, N.-E.3    Transbol, I.4
  • 24
    • 0023690523 scopus 로고
    • Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats
    • Wronski TJ, Cintron M, Doherty AL, Dann LM (1988) Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endocrinology 123:681-686
    • (1988) Endocrinology , vol.123 , pp. 681-686
    • Wronski, T.J.1    Cintron, M.2    Doherty, A.L.3    Dann, L.M.4
  • 25
    • 0023803311 scopus 로고
    • Temporal relationship between bone loss and increased bone turnover in ovariectomized rats
    • Wronski TJ, Cintron M, Dann LM (1988) Temporal relationship between bone loss and increased bone turnover in ovariectomized rats. Calcif Tissue Int 43:179-183
    • (1988) Calcif Tissue Int , vol.43 , pp. 179-183
    • Wronski, T.J.1    Cintron, M.2    Dann, L.M.3
  • 26
    • 0027139169 scopus 로고
    • The estrogen antagonist ICI 182,780 reduces cancellous bone volume in female rats
    • Gallagher A, Chambers TJ, Tobias JH (1993) The estrogen antagonist ICI 182,780 reduces cancellous bone volume in female rats. Endocrinology 133:2787-2791
    • (1993) Endocrinology , vol.133 , pp. 2787-2791
    • Gallagher, A.1    Chambers, T.J.2    Tobias, J.H.3
  • 27
    • 0018694377 scopus 로고
    • Quantum concept of bone remodeling and turnover: Implications for the pathogenesis of osteoporosis
    • Parfitt AM (1979) Quantum concept of bone remodeling and turnover: implications for the pathogenesis of osteoporosis. Calcif Tissue Int 28:1-5
    • (1979) Calcif Tissue Int , vol.28 , pp. 1-5
    • Parfitt, A.M.1
  • 29
    • 0023320347 scopus 로고
    • The effects of ovariectomy and 17β-estradiol on cortical bone histomorphometry in growing rats
    • Turner RT, Vandersteenhoven JJ, Bell NH (1987) The effects of ovariectomy and 17β-estradiol on cortical bone histomorphometry in growing rats. J Bone Miner Res 2:115-122
    • (1987) J Bone Miner Res , vol.2 , pp. 115-122
    • Turner, R.T.1    Vandersteenhoven, J.J.2    Bell, N.H.3
  • 30
    • 0026624822 scopus 로고
    • 17β-estradiol stimulates cancellous bone formation in female rats
    • Chow JWM, Lean JM, Chambers TJ (1992) 17β-estradiol stimulates cancellous bone formation in female rats. Endocrinology 130:3025-3032
    • (1992) Endocrinology , vol.130 , pp. 3025-3032
    • Chow, J.W.M.1    Lean, J.M.2    Chambers, T.J.3
  • 32
    • 0027160207 scopus 로고
    • Estrogen does not restore bone lost after ovariectomy in the rat
    • Abe T, Chow JWM, Lean JM, Chambers TJ (1993) Estrogen does not restore bone lost after ovariectomy in the rat. J Bone Miner Res 8:831-838
    • (1993) J Bone Miner Res , vol.8 , pp. 831-838
    • Abe, T.1    Chow, J.W.M.2    Lean, J.M.3    Chambers, T.J.4
  • 34
    • 0027942671 scopus 로고
    • Role of androgens in the regulation of the human menstrual cycle
    • Rossmanith WG, Schenkel B, Benz R (1994) Role of androgens in the regulation of the human menstrual cycle. Gynecol Endocrinol 8:151-159
    • (1994) Gynecol Endocrinol , vol.8 , pp. 151-159
    • Rossmanith, W.G.1    Schenkel, B.2    Benz, R.3
  • 38
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • Orentreich N, Brind JL, Rizer RL, Vogelman JH (1984) Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab 59:551-555
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.H.4
  • 39
    • 0017739464 scopus 로고
    • Plasma androstenedione and oestrone levels in normal and osteoporotic postmenopausal women
    • Marshall DH, Crilly RG, Nordin BEC (1977) Plasma androstenedione and oestrone levels in normal and osteoporotic postmenopausal women. Br Med J 2:1177-1179
    • (1977) Br Med J , vol.2 , pp. 1177-1179
    • Marshall, D.H.1    Crilly, R.G.2    Nordin, B.E.C.3
  • 40
    • 0017804590 scopus 로고
    • The relation among plasma androstenedione, plasma oestrone and androstenedione to oestrone conversion rates on postmenopausal women with and without fractures
    • Pelc B, Marshall DH, Guha P, Khan MY, Nordin BEC (1978) The relation among plasma androstenedione, plasma oestrone and androstenedione to oestrone conversion rates on postmenopausal women with and without fractures. Clin Sci Mol Med 54:125-131
    • (1978) Clin Sci Mol Med , vol.54 , pp. 125-131
    • Pelc, B.1    Marshall, D.H.2    Guha, P.3    Khan, M.Y.4    Nordin, B.E.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.