Role of insulin-like growth factors in autocrine growth of human retinoblastoma Y79 cells

European Journal of Biochemistry

Volumn 236, Issue 2, 1996, Pages 523-532

  Giuliano, Michela ^a   Vento, Renza ^a   Lauricella, Marianna ^a   Calvaruso, Giuseppe ^a   CarabillO', Maria ^a   Tesoriere, Giovanni ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

autocrine growth; human retinoblastoma; insulin; insulin like growth factor I; Y79 cells

Indexed keywords

INSULIN; INSULIN RECEPTOR; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RETINOBLASTOMA;

EID: 0029872713     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.00523.x     Document Type: Article

References (63)

1. Kyritsis, A. P., Tsokos, M., Triche, T. J. & Chader, G. J. (1984) Retinoblastoma origin from a primitive neuroectodermal cell, Nature 307, 471-473.
2. Benedict, W. F., Murphree, A. L., Banerjee, A., Spina, C. A., Sparkes, M. C. & Sparkes, R. S. (1983) Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene, Science 219, 973-975.
3. Cavenee, W. K., Dryja, T. P., Phillips, R. A., Benedict, W. F., Godbout, R., Gallie B. L., Murphree, A. L., Strong, L. C. & White, R. L. (1983) Expression of recessive alleles by chromosomal mechanisms in retinoblastoma, Nature 305, 779-784.
4. Knudson, A. G. (1971) Mutation and cancer: statistical study of retinoblastoma, Proc. Natl Acad. Sci. USA 68, 820-823.
5. Knudson, A. G. (1973) Mutation and human cancer, Adv. Cancer Res. 17, 317-352.
6. Abramson, D. H., Ellsworth, R. M., Kitchin, D. & Tung, G. (1984) Second nonocular tumors in retinoblastoma survivors, Ophthalmology 91, 1351-1355.
7. Lee, W-H., Shew, J. K., Hong, F., Sery, T., Donoso, L. A., Young, L. J., Bookstein, R. & Lee, E. Y. H. P. (1987) The retinoblastoma susceptibility gene product is a nuclear phosphoprotein associated with DNA binding activity, Nature 329, 642-645.
8. Horowitz, J. M., Park, S. H., Bogenmann, E., Cheng, J. C., Yandell, D. W., Kaye, F. J., Minna, Y. D., Dryja, T. P. & Weinberg, R. A. (1990) Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells, Proc. Natl Acad. Sci. USA 87, 2775-2779.
9. Cheng, J., Scully, P. Schew, J.-Y., Lee, W.-H., Vila, V. & Haas, M. (1990) Homozygous deletion of retinoblastoma gene in an acute lymphoblastic leukemia (T) cell line, Blood 75, 730-735.
10. Friend, S. H., Horowitz, J. M., Gerber, M. R., Wang, X.-F., Bogenman, E., Li., F. P. & Weinberg, R. A. (1487) Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein, Proc. Natl Acad. Sci. USA 84, 9059-9063.
11. Hensel, C. H., Hsieh, C. L., Gazdar, A. F., Johnson, B. E., Sakaguchi, A. Y., Naylor, S. L., Lee, W.-H. & Lee, Y.-H. P. (1990) Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer, Cancer Res. 50, 3067-3072.
12. Lee, E. Y.-H. P., To, H., Shew, J.-Y., Bookstein, E. R., Scully, P. & Lee, W.-H. (1988) Inactivation of the retinoblastoma susceptibility gene in human breast cancers, Science 41, 218-221.
13. Shew, J. Y., Lin, B., Chen, P-L., Tseng, B. Y., Yang-Feng, T. L. & Lee, W.-H. (1990) C-Terminal truncation of the RB protein leads to functional inactivation, Proc. Natl Acad. Sci. USA 87, 6-10.
14. Vento, R., Tesoriere, G., Giuliano, M., Calvaruso, G., Lauricella, M. & Carabillo', M. (1994) Synthesis of insulin and its effects in Y79 human retinoblastoma cells, Exp. Eye Res. 59, 1541-1549.
15. Das, A., Pansky, B., Budd, G. C. & Reid, T. W. (1991) Human retinoblastoma Y79 cells both insulin-specific mRNA and insulin-binding sites, Neurosci. Lett. 121, 231-233.
16. Yorek, M. A., Spector, A. A. & Ginsberg, B. H. (1985) Characterization of an insulin receptor in the human Y79 retinoblastoma cells, J. Neurochem. 45, 1590-1595.
17. Saviolakis, G. A., Kyritsis, A. P. & Chader, G. J. (1986) Human Y79 retinoblastoma cells exhibit specific insulin receptors, J. Neurochem. 47, 70-76.
18. Yorek, M. A., Dunlap, J. A. & Ginsberg, B. H. (1987) Aminoacid and putative neurotransmitter transport in human Y79 retinoblastoma cells, J. Biol. Chem. 262, 10986-10993.
19. Kyritsis, A., Tsokos, M. & Chader, G. (1984) Attachment culture of human retinoblastoma cells: long-term culture conditions and effects of dibutyryl cyclic AMP, Exp. Eye Res. 38, 411-421.
20. Nielsen, F. C., Wang, E. & Gammeltoft, S. (1991) Receptor binding, endocytosis, and mitogenesis of insulin-like growth factor I and II in fetal rat brain neurons, J. Neurochem. 56, 12-21.
21. 125I]-epidermal growth factor BALB 3T3 cells, J. Biol. Chem. 255, 1239-1241.
22. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-681.
23. Pietrzkowski, Z., Sell, C., Lammers, R., Ullrich, A. & Basega, R. (1992) Roles of insulin like growth factor 1 (IGF-1) receptor in epidermal growth factor-stimulated growth of 3T3 cells, Mol. Cell. Biol. 12, 3883-3889.
24. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application and cytotoxicity assay, J. Immunol. Methods 65, 55-63.
25. Stewart, A. J., Johnson, M. D., May, F. E. B. & Westley, B. R. (1990) Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen stimulated proliferation of human breast cancer cells, J. Biol. Chem. 34, 21 172-21 178.
26. Martin, D. M., Singleton, J. R., Meghani, M. A. & Feldman, E. L. (1993) IGF receptor function and regulation in autocrine human neuroblastoma cell growth, Regul. Pept. 48, 225-232.
27. Tesoriere, G., Vento, R., Morello, V., Tomasino, R. M., Carabillo', M. & Lauricella, M. (1995) Chick embryo retina development in vitro: the effect of insulin, Neurochem. Res. 20, 803-813.
28. Baker, J., Liu, J.-P. Robertson, E. J. & Efstratiadis, A. (1993) Role of insulin-like growth factors in embryonic and postnatal growth, Cell 75, 73-82.
29. Werner, H., Woloschak, M., Stannard, B., Shen-Orr, Z., Roberts, C. T. & LeRoith, D. (1991) The insulin-like growth factor 1 receptor: molecular biology, heterogeneity, and regulation. in Insulin-like growth factors: molecular and cellular aspects (LeRoith, D., ed.) pp. 17-47. Boca Raton, FL: CRC Press.
30. Lowe, W. L. (1991) Biological actions of the insulin-like growth factors in Insulin-like growth factors: molecular and cellular aspects (LeRoith, D., ed.) pp. 49-85. Boca Raton, FL: CRC Press.
31. Goldring, M. B. & Goldring, S. R. (1991) Cytokines and cell growth control, Eukar. Gene Exp. 1, 301-326.
32. Osborne, C. K., Clemmons, D. R. & Arteaga, C. L. (1990) Regulation of breast cancer growth by insulin-like growth factors, J. Steroid Biochem. Mol. Biol. 37, 805-809.
33. Kleinman, D., Roberts, C. T. Jr., LeRoith, D., Schally, A. V., Levy, J. & Sharoni, Y. (1993) Regulation of endometrial cancer cell growth by insulin-like growth factors and the luteinizing hormone-releasing hormone antagonist SB-75, Regul. Pepl. 48, 91-98.
34. Pepe, M. G., Ginzton, N. H., Lee, P. D. K., Hintz, R. L. & Greenberg, P. (1987) Receptor binding and mitogenic effect of insulin and insulin-like growth factor I and II for human myeloid leukemia cells, J. Cell. Physiol. 133, 219-227.
35. Sell, C., Dumenil, G., Deveaud, C., Miura, M., Coppola, D., DeAngelis, T., Rubin, R., Efstratiadis, A. & Baserga, R. (1994) Effect of a null mutation of the type 1 IGF receptor gene on growth and trasformation of mouse embryo fibroblasts, Mol. Cell. Biol. 14, 3604-3612.
36. Coppola, D., Ferber, A., Miura, M., Sell, C., D'Ambrosio, C., Rubin, R. & Baserga, R. (1994) A functional insulin-like growth factor I receptor is required for the mitogenic and trasforming activities of epidermal growth factor receptor, Mol. Cell. Biol. 14, 4588-4595.
37. Kaleko, M., Rutter, W. G. & Miller, A. D. (1990) Overexpression of the human insulin-like growth factor 1 receptor promotes ligand-dependent neoplastic trasformation, Mol. Cell. Biol. 10, 464-473.
38. Kozma, L. M. & Weber, M. J. (1990) Constitutive phosphorylation of the receptor for insulin like growth factor I in cells trasformed by the src oncogene, Mol. Cell. Biol. 10, 3626-3634.
39. Resnicoff, M., Coppola, D., Sell, C., Rubin, R., Ferrone, S. & Baserga, R. (1994) Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor, Cancer Res. 54, 4848-4850.
40. Resnicoff, M., Sell C., Rubini, M., Coppola, D., Ambrose, D., Baserga, R. & Rubin, R. (1994) Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor 1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors, Cancer Res. 54, 2218-2222.
41. cdc2, Cancer Res. 54, 5531-5534.
42. Drummond, I. A., Madden, S. L., Rohwer-Nutter, P., Bell, G. I., Sukhatme, V. P. & Rauscher III, F. J. (1992) Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1, Science 257, 674-678.
43. Meghani, M. A., Martin, D. M., Singleton, J. R. & Feldman, E. N. (1993) Effects of serum and insulin-like growth factors in human neuroblastoma cell growth, Regul. Pept. 48, 217-224.
44. Goodrich, D. W., Wang, N. P., Qian, Y.-W., Lee, E.-Y.-H. P. & Lee, W.-H. (1991) The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 67, 293-302.
45. Cobrimik, D., Dowdy, S. F. Hinds, P. W., Mittnacht, S. & Weinberg, R. A. (1992) The retinoblastoma protein and the regulation of cell cycling, Trends Biochem. Sci. 17, 312-315.
46. Ewen, M. E., Sluss, H. K., Sherr, C. J., Matsushime, H., Kato, J. Y. & Livingston, D. M. (1993) Functional interactions of the retinoblastoma protein with mammalian D-type cyclins, Cell 73, 487-497.
47. Dowdy, S. F., Hinds, P. W., Louie, K., Reed, S. I., Arnold, A. & Weinberg, R. A. (1993) Physical interaction of the retinoblastoma protein with human D cyclins, Cell 73, 499-511.
48. Kato, J., Matsushime, H., Hiebert, S. W., Ewen, M. E. & Sherr, C. J. (1993) Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4, Genes & Dev. 7, 331-342.
49. Nevins, J. R. (1992) E2F: A link between the Rb tumor suppressor protein and viral oncoproteins, Science 258, 424-429.
50. Chittenden, T., Livingston, D. M. & De Caprio, J. A. (1993) Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F, Mol. Cell. Biol. 13, 3975-3983.
51. Weintraub, S. J., Prater, C. A. & Dean, D. C. (1992) Retinoblastoma protein switches the E2F site from a positive to a negative element, Nature 358, 259-261.
52. Chellappan, S. P., Hiebert, S., Mudryj, M., Horowitz, J. M. & Nevins J. A. (1991) The E2F transcription factor is a cellular target for the RB protein, Cell 65, 1053-1061.
53. Welch P. J. & Wang, J. Y. J. (1993) A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-abl tyrosine kinase in the cell cycle, Cell 75, 779-790.
54. Wang, C. Y. Petrymiak, B., Thompson, C. B., Kaelin, W. G., Leiden, J. M. (1993) Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein, Science 260, 1330-1335.
55. DeCaprio, J. A., Ludlow, J. W., Lynch, D., Furukawa, Y. Griffin, J., Piwnica-Worms, H. Huang, C. M. & Livingston, D. M. (1989) The product of retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58, 1085-1095.
56. Dyson, N. Howley, P. M., Munger, K. & Harlow, E. (1989) The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product, Science 243, 934-937.
57. Lee E. Y.-H. P., Chang, C. Y., Hu, N. P., Wang, Y. C. I., Lui, C. C., Herrup, K., Lee, W. H. & Bradley. (1992) A mice deficient for RB are nonviable and show detects in neurogenesis and hematopoiesis, Nature 359, 288-294.
58. Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A. & Weinberg, R. A. (1992) Effects of an Rb mutation in the mouse, Nature 359, 295-300.
59. Clarke, A. R., Maandag, E. R., Vanroon, M., Vanderlugt, N. M. T., Vandervalk, M. Hooper, M. L., Verns, A. & Riele, H. T. (1992) Requirement for a functional Rh-1 gene in murine development, Nature 359, 328-330.
60. Hinds, P. W. & Weinberg, R. A. (1994) Tumor suppressor genes, Curr. Opin. Gen. Dev. 4, 135-141.
61. Williams, B. O., Remington, L., Albert, D. M., Mukai, S., Bronson, R. T. & Jacks, T. (1994) Cooperative tumorigenic effects of germline mutations in Rb and p53. Nature Genet. 7, 480-484.
62. Harvey, M., Vogel, H., Lee, E. Y., Brabley, A. & Donehower, L. A. (1995) Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin, Cancer Res 55, 1146-1151.
63. Wolff, J. M. Stephenson, R. N., Jakse, G. & Habib, F. K. (1994) Retinoblastoma and p53 genes as prognostic indicators in urological oncology, Urol. Int. 53, 1-5.