The morphologic spectrum of non-Hodgkin's lymphomas with BCL1/cyclin D1 gene rearrangements

American Journal of Surgical Pathology

Volumn 20, Issue 5, 1996, Pages 627-640

  Swerdlow, Steven H ^a,d   Zukerberg, Lawrence R ^b   Yang, Woo Ick ^b   Harris, Nancy L ^b   Williams, Michael E ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

BCL1; Centrocytic lymphoma; Cyclin D1; Hairy cell leukemia; Mantle cell lymphoma; Marginal zone lymphoma; Parafollicular or monocytoid B cell lymphoma; PRAD1; Splenic lymphoma with villous lymphocytes

Indexed keywords

CYCLINE;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CANCER GENETICS; CELL ULTRASTRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; GENE REARRANGEMENT; HAIRY CELL LEUKEMIA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; NONHODGKIN LYMPHOMA;

ADULT; AGED; AGED, 80 AND OVER; CYCLINS; DIAGNOSIS, DIFFERENTIAL; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTES; LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE; MALE; MIDDLE AGED;

EID: 0029872535     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199605000-00009     Document Type: Article

References (42)

1. Adami F, Chilosi M, Lestani M, et al. A CD5+ leukemic lymphoma with monocytoid features: an unusual B-cell lymphoma mimicking hairy-cell leukemia. Acta Haematol 1993; 89:94-9.
2. Adami F, Semenzato G, Menestrina F, Chilosi M. CD5+ leukemic monocytoid B-cell lymphoma and lymphocytic lymphomas [Letter]. Am J Clin Pathol 1993;100:187-8.
3. Agnarsson BA, Kadin ME. An unusual B-cell lymphoma simulating hairy cell leukemia. Am J Clin Pathol 1987;88: 752-9.
4. Arber DA, Sheibani K, Weiss LM. UCL3D3 and UCL4D12 reactivity in small B-cell neoplasms with special emphasis on monocytoid B-cell lymphoma. Hum Pathol 1994;25: 1084-90.
5. Bosch F, Jares P, Campo E, et al. PRAD1/Cyclin D1 gene overexpression in chronic lymphoproliferative disorders: a highly specific marker of mantle cell lymphoma. Blood 1994; 84:2726-32.
6. Brito-Babapulle V, Ellis J, Matutes E, et al. Translocation t(11;14) (q13;q32) in chronic lymphoid disorders. Genes Chromosom Cancer 1992;5:158-65.
7. Cook P, Pugh WC. CD5 antigen expression in low grade B cell lymphomas of mucosa-associated lymphoid tissue (LGBL/MALT) [Abstract]. Mod Pathol 1994;7:106A.
8. de Boer CJ, Loyson S, Kluin PM, Kluin-Nelemans HC, Schuuring E, vanKrieken JHJM. Multiple breakpoints within the BCL-1 locus in B-cell lymphoma: rearrangements of the cyclin D1 gene. Cancer Res 1993;53:4148-52.
9. 8a. Ferry JA, Yang W-I, Zuckerberg LR, Wotherspoon AC, Arnold A, Harris NL. CD5+ extranodal marginal zone B-cell (MALT) lymphoma. A low grade neoplasm with a propensity for bone marrow involvement and relapse. Am J Clin Pathol 1996;105:31-7.
10. Fisher RI, Dahlbert S, Nathwani BN, Banks PM, Miller TP, Grogan TM. A clinical analysis of two indolent lymphoma entities: mantle cell lymphoma and marginal zone lymphoma (including the mucosa-associated lymphoid tissue and monocytoid B-cell subcategories): a Southwest Oncology Group Study. Blood 1995;85:1075-82.
11. Harris NL, Nadler LM, Bhan AK. Immunohistologic characterization of two malignant lymphomas of germinal center type (centroblastic/centrocytic and centrocytic) with monoclonal antibodies. Follicular and diffuse lymphomas of small-cleaved-cell type are related but distinct entities. Am J Pathol 1984;117:262-72.
12. Isaacson PG, Matutes E, Burke M, Catovsky D. The histopathology of splenic lymphoma with villous lymphocytes. Blood 1994;84:3838-4.
13. Isaacson PG, Wotherspoon AC, Diss T, Pan L. Follicular colonization in B-cell lymphoma of mucosa-associated lymphoid tissue. Am J Surg Pathol 1991;15:819-28.
14. Jadayel D, Matutes E, Dyer MJS, et al. Splenic lymphoma with villous lymphocytes: analysis of BCL1 rearrangements and expression of the cyclin D1 gene. Blood 1994;83:3664-71.
15. Lardelli P, Bookman MA, Sundeen J, Longo DL, Jaffe ES. Lymphocytic lymphoma of intermediate differentiation. Morphologic and immunophenotypic spectrum and clinical correlations. Am J Surg Pathol 1990;14:752-63.
16. Lennert K, Stein H, Kaiserling E. Cytological and functional criteria for the classification of malignant lymphomata. Br J Cancer 1975;31(suppl II):29-43.
17. Nathwani BH, Mohrmann RL, Brynes RK, Taylor CR, Hansmann ML, Sheibani K. Monocytoid B-cell lymphomas: an assessment of diagnostic criteria and a perspective on histogenesis. Hum Pathol 1992;23:1061-71.
18. Ott MM, Ott G, Kuse R, et al. The anaplastic variant of centrocytic lymphoma is marked by frequent rearrangements of the BCL1 gene and high proliferation indices. Histopathology 1994;24:329-34.
19. Raynaud SD, Bekri S, Leroux D, et al. Expanded range of 11q13 breakpoints with differing patterns of cyclin D1 expression in B-cell malignancies. Genes Chromosom Cancer 1993;8:80-7.
20. Rimokh R, Berger F, Delsol G, et al. Rearrangement and overexpression of the BCL1/PRAD-1 gene in intermediate lymphocytic lymphomas and in t(11q13)-bearing leukemias. Blood 1993;81:3063-7.
21. Segal GH, Masih AS, Fox AC, Jorgensen T, Scott M, Braylan RC. CD5-expressing B-cell non-Hodgkin's lymphomas with bcl-1 gene rearrangement have a relatively homogeneous immunophenotype and are associated with an overall poor prognosis. Blood 1995;85:1570-9.
22. Sheibani K, Burke JS, Swartz WG, Nademanee A, Winberg CD. Monocytoid B-cell lymphoma. Clinicopathologic study of 21 cases of a unique type of low-grade lymphoma. Cancer 1988;62:1531-8.
23. Slovak ML, Weiss LM, Nathwani BN, Bernstein L, Levine AM. Cytogenetic studies of composite lymphomas: monocytoid B-cell lymphoma and other B-cell non-Hodgkin's lymphomas. Hum Pathol 1993;24:1086-94.
24. Swerdlow SH, Westermann CD, Pelstring RP, Saboorian MH, Williams ME. Growth fraction in centrocytic and follicular center cell lymphomas: assessment in paraffin sections with a proliferating cell nuclear antigen antibody and morphometric correlates. Hum Pathol 1993;24:540-6.
25. Swerdlow SH, Williams ME. Centrocytic lymphoma: a distinct clinicopathologic, immunophenotypic, and genotypic entity. Pathol Annu 1993;28(Part 2):171-97.
26. Swerdlow SH, Saboorian MH, Pelstring RJ, Williams ME. Centrocytic lymphoma: a morphometric study with comparison to other small cleaved follicular center cell lymphomas and genotypic correlates. Am J Pathol 1993;142:329-37.
27. Swerdlow SH, Habeshaw JA, Murray LJ, Dhaliwal HS, Lister TA, Stansfeld AG. Centrocytic lymphoma: a distinct clinicopathologic and immunologic entity. A multiparameter study of 18 cases at diagnosis and relapse. Am J Pathol 1983;113:181-97.
28. Swerdlow SH, Yang W-I, Zukerberg LR, Harris NL, Arnold A, Williams ME. Expression of cyclin D1 protein in centrocytic/mantle cell lymphomas with and without rearrangement of the BCL1/cyclin D1 gene. Hum Pathol 1995;26:999-1004.
29. Tolksdorf G, Stein H, Lennert K. Morphological and immunological definition of a malignant lymphoma derived from germinal-centre cells with cleaved nuclei (centrocytes). Br J Cancer 1980;41:168-82.
30. Traweek ST, Sheibani K. Monocytoid B-cell lymphoma. The biologic and clinical implications of peripheral blood involvement. Am J Clin Pathol 1992;97:591-8.
31. Traweek ST, Winberg CD, Sheibani K. Monocytoid B-Cell lymphoma: point on a spectrum [Letter]. Am J Clin Pathol 1988;90:748-9.
32. Williams ME, Swerdlow SH, Meeker TC. Chromosome t(11;14) (q13; q32) breakpoints in centrocytic lymphoma are highly localized at the BCL1 major translocation cluster. Leukemia 1993;7:1437-40.
33. Williams ME, Swerdlow SH, Rosenberg CL, Arnold A. Chromosome 11 translocation breakpoints at the PRAD 1/cyclin D1 gene locus in centrocytic lymphoma. Leukemia 1993;7:241-5.
34. Williams ME, Westermann CD, Swerdlow SH. Genotypic characterization of centrocytic lymphoma: Frequent rearrangement of the chromosome 11 BCL1 locus. Blood 1990; 76:1387-91.
35. Williams ME, Swerdlow SH. Cyclin D1 overexpression in non-Hodgkin's lymphoma with chromosome 11 BCL1 rearrangement. Ann Oncol 1994;5(Suppl 1):S71-3.
36. Williams ME, Swerdlow SH, Rosenberg CL, Arnold A. Centrocytic lymphoma: a B-cell non-Hodgkin's lymphoma characterized by chromosome 11 bcl-1 and PRAD1 rearrangements. Curr Top Micro Immuno 1992;182:325-9.
37. Williams ME, Meeker TC, Swerdlow SH. Rearrangement of the chromosome 11 BCL1 locus in centrocytic lymphoma: analysis with multiple breakpoint probes. Blood 1991;78: 493-8.
38. Williams ME, Zukerberg LR, Harris NL, et al. Mantle cell/ centrocytic lymphoma: molecular and phenotypic analysis including analysis of the bcl-1 major translocation cluster by PCR. Curr Topics Microbiol Immunol 1994;194:341-6.
39. Yang W-I, Zukerberg LR, Motokura T, Arnold A, Harris NL. Cyclin D1 (BCL-1/PRAD1) protein expression in low-grade B-cell lymphomas and reactive hyperplasia. Am J Pathol 1994;145:86-96.
40. Zucca E, Stein H, Coiffier B on behalf of the European Lymphoma Task Force. European Lymphoma Task Force (ELTF): report of the Workshop on Mantle Cell Lymphoma (MCL). Ann Oncol 1994;5:507-11.
41. Zukerberg LR, Yang WI, Arnold A, Harris NL. Cyclin D1 (PRAD1/BCL1) expression in non-Hodgkin's lymphomas: detection by paraffin-section immunohistochemistry. Blood 1994;84(Suppl 1):449a.
42. Zukerberg LR, Medeiros LJL, Ferry JA, Harris NL. Diffuse low-grade B-cell lymphomas. Four clinically distinct subtypes defined by a combination of morphologic and immunophenotypic features. Am J Clin Pathol 1993;100:373-85.