Cyclosporin does not inhibit the tubular secretion of creatinine

Nephrology Dialysis Transplantation

Volumn 11, Issue 5, 1996, Pages 833-836

  Hilbrands, L B ^a   Wetzels, J F M ^a   Hoitsma, A J ^a   Koene, R A P ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cimetidine; Creatinine clearance; Cyclosporin; Glomerular filtration rate; Renal transplantation; Tubular creatinine secretion

Indexed keywords

AZATHIOPRINE; CIMETIDINE; CREATININE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DRUG WITHDRAWAL; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; KIDNEY TUBULE EXCRETION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0029872375     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.ndt.a027408     Document Type: Article

References (19)

1. Chapman JR, Harding NGL, Griffiths D, Morris PJ. Reversibility of cyclosporin nephrotoxicity after three months' treatment. Lancet 1985; 1: 128-129
2. Almond PS, Gillingham KJ, Sibley R et al. Renal transplant function after ten years of cyclosporine. Transplantation 1992; 53: 316-323
3. Burke JFJ, Pirsch JD, Ramos EL et al. Long-term efficacy and safety of cyclosporine in renal transplant recipients. N Engl J Med 1994; 331: 358-363
4. Conte G, Dal-Canton A, Sabbatini M et al Acute cyclosporine renal dysfunction reversed by dopamine infusion in healthy subjects. Kidney Int 1989; 36: 1086-1092
5. Mihatsch MJ, Thiel G, Ryffel B. Histopathology of cyclosporine nephrotoxicity. Transplant Proc 1988; 20: 759-771
6. Grantham JJ, Chonko AM. Renal handling of organic anions and cations; excretion of uric acid. In: Brenner BM, Rector FC, eds. The Kidney. W. B. Saunders Company, Philadelphia, 1991, 483-509
7. Edwards BD, Maiza A, Daley Yates PT et al. Altered clearance of N-1 methylnicotinamide associated with the use of low doses of cyclosporine. Am J Kidney Dis 1994; 23: 23-30
8. Noordzij TC, Leunissen KM, van Hooff JP. Renal handling of urate and the incidence of gouty arthritis during cyclosporine and diuretic use. Transplantation 1991; 52: 64-67
9. Hilbrands LB, Artz MA, Wetzels JFM, Koene RAP. Cimetidine improves the reliability of creatinine as a marker of glomerular filtration. Kidney Int 1991; 40: 1171-1176
10. van Acker BAC, Koomen GCM, Koopman MG, de Waart DR, Arisz L. Creatinine clearance during cimetidine administration for measurement of glomerular filtration rate. Lancet 1992; 340: 1326-1329
11. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31-41
12. Bauer JH, Brooks CS, Burch RN. Clinical appraisal of creatinine clearance as a measurement of glomerular filtration rate. Am J Kidney Dis 1982; 2: 337-346
13. Shemesh O, Golbetz H, Kriss JP, Myers BD. Limitations of creatinine as a filtration marker in glomerulopathic patients. Kidney Int 1985; 28. 830-838
14. Wetzels JFM, Huysmans FThM, Koene RAP. Creatinine as a marker of glomerular filtration rate. Neth J Med 1988; 33: 144-153
15. van Acker BAC, Koomen GCM, Koopman MG, Arisz L. Increased disparity between creatinine and inulin clearance in renal disease: relation to filtration fraction. J Am Soc Nephrol 1992; 3: 322(abstract)
16. Versluis DJ. The use of cyclosporine A and azathioprine in clinical kidney transplantation. [Thesis] Rotterdam, 1989; 35-46
17. 125I iothalamate an ideal marker for glomerular filtration? Kidney Int 1985; 27: 9-16
18. Ross EA, Wilkinson A, Hawkins RA, Danovitch GM. The plasma creatinine concentration is not an accurate reflection of the glomerular filtration rate in stable renal transplant patients receiving cyclosporine. Am J Kidney Dis 1987; 10: 113-117
19. Rodier M, Ribstein J, Parer-Richard C, Mimran A. Renal changes associated with cyclosporine in recent type I diabetes mellitus. Hypertension 1991; 18: 334-340