Different patterns of TCR transgene expression in single-positive and double-negative T cells: Evidence for separate pathways of T cell maturation

Journal of Immunology

Volumn 156, Issue 10, 1996, Pages 3591-3601

  Cheng, Lirong ^a   Dejbakhsh Jones, Sussan ^a   Liblau, Roland ^a   Zeng, DeFu ^a   Strober, Samuel ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW; CELL MATURATION; GENE EXPRESSION REGULATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; THYMUS; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BONE MARROW; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CROSSES, GENETIC; MICE; MICE, INBRED BALB C; MICE, NUDE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS; TRANSGENES;

EID: 0029872289     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Makino, Y., N. Yamagata, T. Sasho, Y Adachi, R. Kanno, H. Koseki, M. Kanno, and M. Taniguchi 1993. Extrathymic development of Vα14-positive T cells. J. Exp. Med. 177.1399.
2. - αβ bone marrow T cells with suppressor activity. J. Immunol. 148:373
3. Dejbakhsh-Jones, S., H. Okazaki, and S. Strober. 1995. Similar rates of production of T and B lymphocytes in the bone marrow. J. Exp. Med. 181:2201.
4. Benveniste, P., B. S. Chadwick, R. G Miller, and J. Reimann. 1990. Characterization of cells with T cell markers in athymic nude bone marrow and of their in vitro-derived clonal progeny. J. Immunol. 144:411.
5. Martinez-A, C., M. A R. Marcos, I. M. de Alboran, M. Alonso, C. Rafael, G. Kroemer, and A Coutinho 1993. Functional double-negative T cells in the periphery express T cell receptor Vβ gene products that cause deletion of single-positive T cells. Eur. J. Immunol. 23:250.
6. - αβ T cell population with biased T cell receptor V gene usage: presence in bone marrow and possible involvement of IL-3 for their extrathymic development. J Immunol. 149:1143.
7. - cells. J. Exp. Med. 179:1957.
8. + thymocytes. J. Immunol. 146:1113.
9. - T cells in mice and humans. J. Exp. Med. 180:1097.
10. - T cells bearing αβ T cell receptor. J Immunol. 142:3773
11. Von Boehmer, H. 1990. Developmental biology of T cells in T cell-receptor transgenic mice. Annu Rev. Immunol. 8:531.
12. Capone, M., J. Curnow, G. Bouvier, P. Ferrier, and B. Horvat. 1995. T cell development in TCR-αβ transgenic mice: analysis using V(D)J recombination substrates. J. Immunol. 154:5165
13. Hertel-Wulff, B., T Lindsten, R. Schwadron, D. M. Gilbert, M. M. Davis, and S Strober. 1987. Rearrangement and expression of T cell receptor genes in cloned murine natural suppressor cell lines. J. Exp. Med. 166:1168
14. - surface phenotype and the αβ heterodimer of the T cell antigen receptor. J. Immunol. 143:1118.
15. - αβ T suppressor cells. J. Immunol 151:5348.
16. Patten, P. A., E. P. Rock, T. Sonoda, B. F. Groth, J. L. Jorgensen, and M. M. Davis. 1993. Transfer of putative complementarity-determining region loops of T cell receptor domains confers toxin reactivity but not peptide/MHC specificity J Immunol 159:2281.
17. Scott, B., R. Liblau, S Degermann, L. A. Marconi, L. Ogata, A. J. Caton, H. O. McDevitt, and D. Lo. 1994. A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity 1:73.
18. Yague, J , M Blackman, W. Born, P. Marrack, J. Kappler, and E. Palmer. 1988 The structure of Va and Ja segments in the mouse. Nucleic Acids Res. 16.11355.
19. Koop, B. F., R. K. Wilson, K Wang, B. Vernooj, D. Azler, C. L. Kuo, D. Seto, M. Toda, and L. Hood. 1992. Organization, structure, and functions of 95 kb of DNA spanning the murine T-cell receptor Cα/Cγ region. Genomics 13:1209.
20. Behlke, A. M., D. G. Spinella, H. S. Chou, W. Sha, D. L. Hartl, and D. Y. Loh 1985. T-cell receptor β-chain expression: dependence on relatively few variable region genes. Science 229:566.
21. Gordon, J. W., and F. H. Ruddle. 1983. Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol. 101: 411.
22. Brinster, R. L., N. Y. Chen, M. E. Trumbauer, M. K. Yagle, and R. D. Palmitter. 1985. Factors affecting the efficiency of introducing foreign DNA into mice by microinjection Proc. Natl. Acad. Sci. USA 82:4438.
23. Hogan, B., F. Costantini, and E Lacy. 1986. Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
24. Chien, Y. H , D. M. Becker, T. Lindsten, M. Okamura, D. I Cohen, and M. M. Davis 1984. A third Type of T-cell receptor gene Nature 312:31.
25. Gascoigne, R. J. N., Y.-H. Chien, D. M Becker, K. Joshua, and M. M. Davis. 1984 Genomic organization and sequence of T-cell receptor β-chain constant-and joining-region genes. Nature 310:387
26. Palathumpat, V , S. Dejbakhsh-Jones, B. Holm, and S. Strober. 1992. Different subsets of T cells m the adult mouse bone marrow and spleen induce or suppress acute graft-versus-host disease. J. Immunol. 149.808.
27. Von Boehmer, H. 1994. Positive selection of lymphocytes. Cell 76:219.
28. Nossal, G. J. V. 1994 Negative selection of lymphocytes. Cell 76:229
29. + T lymphocytes. Science 268.863.
30. + T cells Nature 372:691.
31. Hertel-Wulff, B , S. Okada, A. Oscroff, and S Strober. 1984. In vitro propagation and cloning of murine natural suppressor (NS) cells. J. Immunol. 133:2791.
32. Strober, S., V. Paiathumpat, R. Schwadron, and B. Hertel-Wulff. 1987. Cloned natural suppressor cells prevent lethal graft versus host disease. J. Immunol 138: 699.
33. -) αβ T cell receptor-bearing cells. J. Immunol. 145: 4046.
34. + cell lines. Cell. Immunol 129.478.