Facile synthetic method for the preparation of dithioacetals by the double conjugate addition of acetylenes bearing electronwithdrawing groups with thiols

Synthetic Communications

Volumn 26, Issue 8, 1996, Pages 1539-1543

  Kuroda, Hirofumi ^a   Tomita, Ikuyoshi ^a   Endo, Takeshi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3,3 BIS(PHENYLTHIO)PROPIONIC ACID METHYL ESTER; DITHIOACETAL DERIVATIVE; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029871673     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608003520     Document Type: Article

References (8)

1. Seebach, D. Synthesis, 1969, 17.
2. Sandler, S. T.; Karo, W. "Organic Functional Group Preparations III, 2nd Ed.", Academic Press, London, 1986, pp. 2-79
3. (a) Prilezhaeva, E. N.; Mikhelashvili, I. L. Zh. Org. Khim. 1973, 9, 1129.
4. (b) Ranu, B. C.; Bhar, S.; Chakraborti, R. J. Org. Chem. 1992, 57, 7349.
5. Inanaga, J.; Baba, Y.; Hanamoto, T. Chem. Lett. 1993, 241.
6. 31P-NMR measurement. Peaks attributable to phosphoniums were detected at 28.9, 41.7, 46.6, 52.9 ppm, in the integral ratio of 1/1.8/84.0/2.5, respectively.
7. 3P]).
8. Brandsma, L. "Preparative Acetylenic Chemistry, 2nd Ed.", Elsevier, 1988, pp. 281.