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Volumn 11, Issue 4, 1996, Pages 196-204

Pilot study of the effect of the simvastatin-ciprofibrate combination on myocardial infarction risk profile in patients with refractory familial combined hyperlipidaemia

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CHOLESTEROL; CIPROFIBRATE; FIBRINOGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SIMVASTATIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 0029871062     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-199611040-00002     Document Type: Article
Times cited : (5)

References (43)
  • 1
    • 0023237538 scopus 로고
    • Familial combined hyperlipidemia work-shop
    • Grundy SM, Chait A, Brunzell JD. Familial combined hyperlipidemia work-shop. Arteriosclerosis 1987; 79 (2): 203-7
    • (1987) Arteriosclerosis , vol.79 , Issue.2 , pp. 203-207
    • Grundy, S.M.1    Chait, A.2    Brunzell, J.D.3
  • 2
    • 0028954936 scopus 로고
    • Dense low-density lipoproteins and coronary artery disease
    • Krauss RM. Dense low-density lipoproteins and coronary artery disease. Am J Cardiol 1995; 75 (6 Suppl.): B53-B57
    • (1995) Am J Cardiol , vol.75 , Issue.6 SUPPL.
    • Krauss, R.M.1
  • 3
    • 0028019136 scopus 로고
    • Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidaemia without changing LDL subclass pattern
    • Franceschini G, Cassinotti M, Vecchio G, et al. Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidaemia without changing LDL subclass pattern. Arterioscler Thromb 1994; 14 (10): 1569-75
    • (1994) Arterioscler Thromb , vol.14 , Issue.10 , pp. 1569-1575
    • Franceschini, G.1    Cassinotti, M.2    Vecchio, G.3
  • 4
    • 0027477869 scopus 로고
    • Dense low-density lipoprotein subspecies with diminished oxidative resistance predominate in combined hyperlipidemia
    • Dejager S, Bruckert E, Chapman MJ. Dense low-density lipoprotein subspecies with diminished oxidative resistance predominate in combined hyperlipidemia. J Lipid Res 1993; 34 (2): 295-308
    • (1993) J Lipid Res , vol.34 , Issue.2 , pp. 295-308
    • Dejager, S.1    Bruckert, E.2    Chapman, M.J.3
  • 6
    • 0023926816 scopus 로고
    • Combination drug therapy for familial combined hyperlipidemia
    • East C, Bilheimer DW, Grundy SM. Combination drug therapy for familial combined hyperlipidemia. Ann Intern Med 1988; 109 (1): 25-32
    • (1988) Ann Intern Med , vol.109 , Issue.1 , pp. 25-32
    • East, C.1    Bilheimer, D.W.2    Grundy, S.M.3
  • 7
    • 0025365041 scopus 로고
    • Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy
    • Pierce LR, Wysowski DK, Gross TP. Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy. JAMA 1990; 264: 71-5
    • (1990) JAMA , vol.264 , pp. 71-75
    • Pierce, L.R.1    Wysowski, D.K.2    Gross, T.P.3
  • 8
    • 0027400118 scopus 로고
    • Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia
    • Wiklund O, Angelin B, Bergman M, et al. Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia. Am J Med 1993; 94 (1): 13-20
    • (1993) Am J Med , vol.94 , Issue.1 , pp. 13-20
    • Wiklund, O.1    Angelin, B.2    Bergman, M.3
  • 9
    • 0028343587 scopus 로고
    • Combined treatment with pravastatin and gemfibrozil in patients with refractory familial combined hyperlipidaemia
    • Athyros V, Papageorgiou A, Hagikonstantinou H, et al. Combined treatment with pravastatin and gemfibrozil in patients with refractory familial combined hyperlipidaemia. Drug Invest 1994; 7 (3): 134-42
    • (1994) Drug Invest , vol.7 , Issue.3 , pp. 134-142
    • Athyros, V.1    Papageorgiou, A.2    Hagikonstantinou, H.3
  • 10
    • 0025817682 scopus 로고
    • The hypolipidaemic effects of pravastatin alone and in combination with bezafibrate or acipimox in patients with primary hypercholesterolaemia
    • Lintott CJ, Scott RS, Nye ER, et al. The hypolipidaemic effects of pravastatin alone and in combination with bezafibrate or acipimox in patients with primary hypercholesterolaemia. Diab Nutr Metab 1991; 4 (1): 1-6
    • (1991) Diab Nutr Metab , vol.4 , Issue.1 , pp. 1-6
    • Lintott, C.J.1    Scott, R.S.2    Nye, E.R.3
  • 11
    • 0027298781 scopus 로고
    • Treatment of severe, resistant familial combined hyperlipidemia with a bezafibrate-lovastatin combination
    • Yeshurun D, Abukarshin R, Elias N, et al. Treatment of severe, resistant familial combined hyperlipidemia with a bezafibrate-lovastatin combination. Clin Ther 1993; 15: 335-63
    • (1993) Clin Ther , vol.15 , pp. 335-363
    • Yeshurun, D.1    Abukarshin, R.2    Elias, N.3
  • 12
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • The Scandinavian Simvastatin Survival Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-9
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 13
    • 0028017562 scopus 로고
    • Effects of ciprofibrate on LDL metabolism in man
    • Gaw A, Packard CJ, Caslake MJ, et al. Effects of ciprofibrate on LDL metabolism in man. Atherosclerosis 1994; 108 (2): 137-48
    • (1994) Atherosclerosis , vol.108 , Issue.2 , pp. 137-148
    • Gaw, A.1    Packard, C.J.2    Caslake, M.J.3
  • 14
    • 0344808386 scopus 로고
    • Long term effect of ciprofibrate in patients with primary hyperlipidemia
    • Oro L, Carson LA, Olsson A, et al. Long term effect of ciprofibrate in patients with primary hyperlipidemia. Curr Ther Res 1992; 51 (2): 229-43
    • (1992) Curr Ther Res , vol.51 , Issue.2 , pp. 229-243
    • Oro, L.1    Carson, L.A.2    Olsson, A.3
  • 15
    • 0028083306 scopus 로고
    • Effect of pravastatin on coronary heart disease prevention in patients with primary hypercholesterolemia
    • Athyros V, Papageorgiou A, Avramides M, et al. Effect of pravastatin on coronary heart disease prevention in patients with primary hypercholesterolemia. Curr Ther Res 1994; 55 (8): 914-24
    • (1994) Curr Ther Res , vol.55 , Issue.8 , pp. 914-924
    • Athyros, V.1    Papageorgiou, A.2    Avramides, M.3
  • 16
    • 0028963432 scopus 로고
    • Long-term effect of gemfibrozil on coronary heart disease risk profile of patients with primary combined hyperlipidemia
    • Athyros V, Papageorgiou A, Avramides M, et al. Long-term effect of gemfibrozil on coronary heart disease risk profile of patients with primary combined hyperlipidemia. Coron Artery Dis 1995; 6 (3): 251-6
    • (1995) Coron Artery Dis , vol.6 , Issue.3 , pp. 251-256
    • Athyros, V.1    Papageorgiou, A.2    Avramides, M.3
  • 17
    • 9244247382 scopus 로고
    • Effect of sustained hyperinsulinemia on coronary heart disease risk factors in salt-sensitive essential hypertensives
    • Kontopoulos A, Athyros V, Papageorgiou A, et al. Effect of sustained hyperinsulinemia on coronary heart disease risk factors in salt-sensitive essential hypertensives. High Blood Press Cardiovasc Prev 1995; 4: 129-36
    • (1995) High Blood Press Cardiovasc Prev , vol.4 , pp. 129-136
    • Kontopoulos, A.1    Athyros, V.2    Papageorgiou, A.3
  • 18
    • 9244243186 scopus 로고
    • A computer program (TYPMI) co-evaluating ten independent coronary heart disease risk factors
    • Papageorgiou A, Athyros V, Avramidis M, et al. A computer program (TYPMI) co-evaluating ten independent coronary heart disease risk factors. Greek Med 1993; 59 (1): 115-23
    • (1993) Greek Med , vol.59 , Issue.1 , pp. 115-123
    • Papageorgiou, A.1    Athyros, V.2    Avramidis, M.3
  • 19
    • 0025313659 scopus 로고
    • Inheritance of low-density lipoprotein subclass pattern in familial combined hyperlipoproteinaernia
    • Austin MA, Brunzell JD, Fitch WL, et al. Inheritance of low-density lipoprotein subclass pattern in familial combined hyperlipoproteinaernia. Arteriosclerosis 1990; 10 (5): 520-30
    • (1990) Arteriosclerosis , vol.10 , Issue.5 , pp. 520-530
    • Austin, M.A.1    Brunzell, J.D.2    Fitch, W.L.3
  • 20
    • 0027408939 scopus 로고
    • Plasma triglyceride and LDL heterogeneity in familial combined hyperlipidemia
    • Hokanson JE, Austin MA, Zambon A, et al. Plasma triglyceride and LDL heterogeneity in familial combined hyperlipidemia. Arterioscler Thromb 1993; 13 (3): 427-34
    • (1993) Arterioscler Thromb , vol.13 , Issue.3 , pp. 427-434
    • Hokanson, J.E.1    Austin, M.A.2    Zambon, A.3
  • 21
    • 0028938572 scopus 로고
    • Comparison of gemfibrozil versus simvastatin in familial combined hyperlipidemia and effects on apolipoprotein-B-containing lipoproteins, low-density lipoprotein subfraction profile, and low-density lipoprotein oxidizability
    • Bredie SJ, de Bruin TW, Demacker PN, et al. Comparison of gemfibrozil versus simvastatin in familial combined hyperlipidemia and effects on apolipoprotein-B-containing lipoproteins, low-density lipoprotein subfraction profile, and low-density lipoprotein oxidizability. Am J Cardiol 1995; 75 (4): 348-53
    • (1995) Am J Cardiol , vol.75 , Issue.4 , pp. 348-353
    • Bredie, S.J.1    De Bruin, T.W.2    Demacker, P.N.3
  • 22
    • 0026723637 scopus 로고
    • Effects of cholestyramine and acipimox on subfractions of plasma LDL. Studies in normolipidaemic and hypercholesterolaemic subjects
    • Griffin BA, Caslake MJ, Gaw A, et al. Effects of cholestyramine and acipimox on subfractions of plasma LDL. Studies in normolipidaemic and hypercholesterolaemic subjects. Eur J Clin Invest 1992; 22: 383-90
    • (1992) Eur J Clin Invest , vol.22 , pp. 383-390
    • Griffin, B.A.1    Caslake, M.J.2    Gaw, A.3
  • 23
    • 0022521147 scopus 로고
    • Genetic control of low-density-lipoprotein subclasses
    • Austin MA, Krauss RM. Genetic control of low-density-lipoprotein subclasses. Lancet 1986; 11 (8507): 592-5
    • (1986) Lancet , vol.11 , Issue.8507 , pp. 592-595
    • Austin, M.A.1    Krauss, R.M.2
  • 24
    • 0025118667 scopus 로고
    • Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk
    • Austin MA, King MC, Vranizan KM, et al. Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk. Circulation 1990; 82 (2): 495-506
    • (1990) Circulation , vol.82 , Issue.2 , pp. 495-506
    • Austin, M.A.1    King, M.C.2    Vranizan, K.M.3
  • 25
    • 0023876839 scopus 로고
    • Drug therapy: HMG CoA reduclase inhibitors for treatment of hypercholesterolemia
    • Grundy SM. Drug therapy: HMG CoA reduclase inhibitors for treatment of hypercholesterolemia. N Engl J Med 1988; 319: 24-32
    • (1988) N Engl J Med , vol.319 , pp. 24-32
    • Grundy, S.M.1
  • 26
    • 0028361107 scopus 로고
    • Role of plasma triglyceride in the regulation of plasma low-density lipoprotein (LDL) subfractions: Relative contribution of small, dense LDL to coronary heart disease risk
    • Griffin BA, Freeman DJ, Tait GW, et al. Role of plasma triglyceride in the regulation of plasma low-density lipoprotein (LDL) subfractions: relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis 1994; 106 (2): 241-53
    • (1994) Atherosclerosis , vol.106 , Issue.2 , pp. 241-253
    • Griffin, B.A.1    Freeman, D.J.2    Tait, G.W.3
  • 27
    • 0028179513 scopus 로고
    • Determinants of LDL subfraction distribution and concentrations in young normolipidemic subjects
    • Watson TD, Caslake MJ, Freeman DJ, et al. Determinants of LDL subfraction distribution and concentrations in young normolipidemic subjects. Arterioscler Thromb 1994; 14 (6): 902-10
    • (1994) Arterioscler Thromb , vol.14 , Issue.6 , pp. 902-910
    • Watson, T.D.1    Caslake, M.J.2    Freeman, D.J.3
  • 28
    • 0027466627 scopus 로고
    • Mechanism of action of fibrates
    • Shepherd J. Mechanism of action of fibrates. Postgrad Med J 1993; 69 Suppl. 1: 34-41
    • (1993) Postgrad Med J , vol.69 , Issue.1 SUPPL. , pp. 34-41
    • Shepherd, J.1
  • 29
    • 0027285331 scopus 로고
    • Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia
    • Bruckert E, Dejager S, Chapman MJ. Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia. Atherosclerosis 1993; 100 (1): 91-102
    • (1993) Atherosclerosis , vol.100 , Issue.1 , pp. 91-102
    • Bruckert, E.1    Dejager, S.2    Chapman, M.J.3
  • 30
    • 0028340315 scopus 로고
    • Effects of bezalibrate therapy on subtractions of plasma LDL and HDL, and on the activities of LCAT and CETP in patients with hyperlipoproteinemia
    • Homma Y, Ozawu H, Kobayashi T, et al. Effects of bezalibrate therapy on subtractions of plasma LDL and HDL, and on the activities of LCAT and CETP in patients with hyperlipoproteinemia. Atherosclerosis 1994; 106 (20): 191-201
    • (1994) Atherosclerosis , vol.106 , Issue.20 , pp. 191-201
    • Homma, Y.1    Ozawu, H.2    Kobayashi, T.3
  • 31
    • 0027225298 scopus 로고
    • Fenofibrate and LDL metabolic heterogeneity in hypercholesterolemia
    • Caslake MJ, Packard CJ, Gaw A, et al. Fenofibrate and LDL metabolic heterogeneity in hypercholesterolemia. Arterioscler Thromb 1993; 13 (5): 702-11
    • (1993) Arterioscler Thromb , vol.13 , Issue.5 , pp. 702-711
    • Caslake, M.J.1    Packard, C.J.2    Gaw, A.3
  • 32
    • 0026754428 scopus 로고
    • Relation of high-density lipoprotein and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Prospective Cardiovascular Munster study
    • Assmann G, Schulte H. Relation of high-density lipoprotein and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Prospective Cardiovascular Munster study. Am J Cardiol 1992; 70 (7): 733-7
    • (1992) Am J Cardiol , vol.70 , Issue.7 , pp. 733-737
    • Assmann, G.1    Schulte, H.2
  • 33
    • 0026586191 scopus 로고
    • Two different views of the relationship of hypertriglyceridemia to coronary heart disease
    • Grundy SM, Vega GL. Two different views of the relationship of hypertriglyceridemia to coronary heart disease. Arch Intern Med 1992; 152: 28-34
    • (1992) Arch Intern Med , vol.152 , pp. 28-34
    • Grundy, S.M.1    Vega, G.L.2
  • 34
    • 0027125530 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes (two parts)
    • Fuster V, Badimon L, Badimon JJ, et al. The pathogenesis of coronary artery disease and the acute coronary syndromes (two parts). N Engl J Med 1992; 326: 242-50, 310-8
    • (1992) N Engl J Med , vol.326 , pp. 242-250
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3
  • 35
    • 0022180444 scopus 로고
    • Effect of ciprofibrate on platelet aggregation and fibrinolysis in patients with hypercholesterolemia
    • Simson IA, Lorimer AR, Walker ID, et al. Effect of ciprofibrate on platelet aggregation and fibrinolysis in patients with hypercholesterolemia. Thromb Haemost 1985; 54: 442-4
    • (1985) Thromb Haemost , vol.54 , pp. 442-444
    • Simson, I.A.1    Lorimer, A.R.2    Walker, I.D.3
  • 36
    • 0027076078 scopus 로고
    • Comparison of the plasma levels of apolipoproteins B and A-1, and other risk factors in men and women with premature coronary artery disease
    • Kwiterovich PO Jr, Coresh J, Smith HH, et al. Comparison of the plasma levels of apolipoproteins B and A-1, and other risk factors in men and women with premature coronary artery disease. Am J Cardiol 1992; 69 (12): 1015-21
    • (1992) Am J Cardiol , vol.69 , Issue.12 , pp. 1015-1021
    • Kwiterovich Jr., P.O.1    Coresh, J.2    Smith, H.H.3
  • 37
    • 0026455110 scopus 로고
    • Effect of pravastatin and cholestyramine on triglyceride-rich lipoprotein particles and Lp(a) in patients with type II hypercholesterolemia
    • Barbi G, Corder CN, Koren E, et al. Effect of pravastatin and cholestyramine on triglyceride-rich lipoprotein particles and Lp(a) in patients with type II hypercholesterolemia. Drug Dev Res 1992; 27: 297-306
    • (1992) Drug Dev Res , vol.27 , pp. 297-306
    • Barbi, G.1    Corder, C.N.2    Koren, E.3
  • 38
    • 0023697436 scopus 로고
    • Efficacy and long-term adverse effect pattern of lovastatin
    • Tobert JA. Efficacy and long-term adverse effect pattern of lovastatin. Am J Cardiol 1988; 62 (15): J28-J34
    • (1988) Am J Cardiol , vol.62 , Issue.15
    • Tobert, J.A.1
  • 40
    • 0027379891 scopus 로고
    • Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin
    • Watts GF, Castelluccio C, Rice-Evans C, et al. Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin. J Clin Pathol 1993; 46: 1055-7
    • (1993) J Clin Pathol , vol.46 , pp. 1055-1057
    • Watts, G.F.1    Castelluccio, C.2    Rice-Evans, C.3
  • 41
    • 0028831354 scopus 로고
    • Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-lerm simvastatin treatment in humans
    • Laaksonen R, Jokelainen K, Sahi T, et al. Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-lerm simvastatin treatment in humans. Clin Pharmacol Ther 1995; 57 (1): 62-6
    • (1995) Clin Pharmacol Ther , vol.57 , Issue.1 , pp. 62-66
    • Laaksonen, R.1    Jokelainen, K.2    Sahi, T.3
  • 42
    • 0026597808 scopus 로고
    • Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment
    • Manninen V, Tenkanen L, Koskinen P, et al. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment. Circulation 1992; 85 (1): 37-45
    • (1992) Circulation , vol.85 , Issue.1 , pp. 37-45
    • Manninen, V.1    Tenkanen, L.2    Koskinen, P.3
  • 43
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995; 333 (20): 1301-7
    • (1995) N Engl J Med , vol.333 , Issue.20 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3


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