-
1
-
-
0345289853
-
Haematological effects of aminoglutethimide in the mouse
-
Ali, H., Nicholls, P. J. (1986) Haematological effects of aminoglutethimide in the mouse. J. Pharm. Pharmacol. 38: 92P
-
(1986)
J. Pharm. Pharmacol.
, vol.38
-
-
Ali, H.1
Nicholls, P.J.2
-
2
-
-
0025051394
-
Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide
-
Ali, H , Khalaf, L., Nicholls, P. J., Poole, A. (1990) Comparison of in vitro and in vivo haemotoxic effects of aminoglutethimide and glutethimide. Toxicology In Vitro 4: 381-383
-
(1990)
Toxicology in Vitro
, vol.4
, pp. 381-383
-
-
Ali, H.1
Khalaf, L.2
Nicholls, P.J.3
Poole, A.4
-
3
-
-
85035168516
-
-
Ph.D. Thesis. University of Wales
-
Ali, H. (1987) Ph.D. Thesis. University of Wales
-
(1987)
-
-
Ali, H.1
-
5
-
-
0024343858
-
Human cytochrome P-450PA (P-450IA2), the phenacetin O-de-ethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
-
Butler, M. A., Iwasaki, M., Guengerich, F. P., Kadlubar, F. F. (1989) Human cytochrome P-450PA (P-450IA2), the phenacetin O-de-ethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc. Natl. Acad. Sci. USA 86: 7696-7700
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7696-7700
-
-
Butler, M.A.1
Iwasaki, M.2
Guengerich, F.P.3
Kadlubar, F.F.4
-
6
-
-
0026598751
-
Use of a metabolic inhibitor to reduce dapsone-dependent haematological toxicity
-
Coleman, M. D., Tingle, M. D. (1992) Use of a metabolic inhibitor to reduce dapsone-dependent haematological toxicity. Drug Dev. Res. 15: 1-16
-
(1992)
Drug Dev. Res.
, vol.15
, pp. 1-16
-
-
Coleman, M.D.1
Tingle, M.D.2
-
7
-
-
0024466393
-
Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes
-
Coleman, M. D., Breckenridge, A. M., Park, B. K. (1989) Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes. Br. J. Clin. Pharmacol. 28: 389-395
-
(1989)
Br. J. Clin. Pharmacol.
, vol.28
, pp. 389-395
-
-
Coleman, M.D.1
Breckenridge, A.M.2
Park, B.K.3
-
8
-
-
0026794121
-
The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients
-
Coleman, M. D., Rhodes, L. A., Scott, A. K., Verbov, J. L., Friedman, P. S., Breckenridge, A. M., Park, B. K. (1992) The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients Br. J. Clin. Pharmacol. 34: 244-249
-
(1992)
Br. J. Clin. Pharmacol.
, vol.34
, pp. 244-249
-
-
Coleman, M.D.1
Rhodes, L.A.2
Scott, A.K.3
Verbov, J.L.4
Friedman, P.S.5
Breckenridge, A.M.6
Park, B.K.7
-
9
-
-
0025038855
-
The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man
-
Coleman, M. D., Scott, A. K., Breckenridge, A. M., Park, B. K. (1990a) The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man. Br. J. Clin. Pharmacol. 30: 761-767
-
(1990)
Br. J. Clin. Pharmacol.
, vol.30
, pp. 761-767
-
-
Coleman, M.D.1
Scott, A.K.2
Breckenridge, A.M.3
Park, B.K.4
-
10
-
-
0028075679
-
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro, IV: Implications for the development of agranulocytosis
-
Coleman, M. D., Simpson, J., Jacobus, D. P. (1994) Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro, IV: implications for the development of agranulocytosis. Biochem. Pharmacol. 48: 1349-1354
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1349-1354
-
-
Coleman, M.D.1
Simpson, J.2
Jacobus, D.P.3
-
11
-
-
0025138389
-
Sex-dependent sensitivity to dapsone-induced methaemoglobinaemia in the rat
-
Coleman, M. D., Winn, M. J., Breckenridge, A. M., Park, B. K. (1990b) Sex-dependent sensitivity to dapsone-induced methaemoglobinaemia in the rat. Biochem. Pharmacol. 39: 805-809
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 805-809
-
-
Coleman, M.D.1
Winn, M.J.2
Breckenridge, A.M.3
Park, B.K.4
-
12
-
-
0009514720
-
Inhibitory effects of β-diethylaminoethyldiphenylpropylacetate on a variety of drug metabolic pathways in vitro
-
Cooper, J. R., Axelrod, J., Brodie, B. B. (1954) Inhibitory effects of β-diethylaminoethyldiphenylpropylacetate on a variety of drug metabolic pathways in vitro. J. Pharmacol. Exp. Ther. 112: 55-63
-
(1954)
J. Pharmacol. Exp. Ther.
, vol.112
, pp. 55-63
-
-
Cooper, J.R.1
Axelrod, J.2
Brodie, B.B.3
-
13
-
-
0015340426
-
Microsomal N-oxidation of dapsone as a cause of methaemoglobin formation in human red cells
-
Cucinell, S. A., Israeli, Z. H., Dayton, P. G. (1972) Microsomal N-oxidation of dapsone as a cause of methaemoglobin formation in human red cells. Am. J. Tropical Med. Hyg. 21: 322-331
-
(1972)
Am. J. Tropical Med. Hyg.
, vol.21
, pp. 322-331
-
-
Cucinell, S.A.1
Israeli, Z.H.2
Dayton, P.G.3
-
14
-
-
0023875548
-
Metabolism profiles and excretion of 14C-aminoglutethimide in several animal species and man
-
Dalrymple, P. D., Nicholls, P. J. (1988) Metabolism profiles and excretion of 14C-aminoglutethimide in several animal species and man. Xenobiotica 18: 75-81
-
(1988)
Xenobiotica
, vol.18
, pp. 75-81
-
-
Dalrymple, P.D.1
Nicholls, P.J.2
-
15
-
-
0003378971
-
Hemoglobin, hemoglobin derivatives and myoglobin
-
Tietz, N.W. (ed.) Saunders, Philadelphia
-
Fairbanks, V. F. (1976) Hemoglobin, hemoglobin derivatives and myoglobin. In: Tietz, N.W. (ed.) Fundamentals of Clinical Chemistry. Saunders, Philadelphia
-
(1976)
Fundamentals of Clinical Chemistry
-
-
Fairbanks, V.F.1
-
16
-
-
0027077439
-
Human liver microsomal N-hydroxylation of dapsone by cytochrome P-4503A4
-
Fleming, C. M., Branch, R. A., Wilkinson, G. R., Guengerich, F, P. (1992) Human liver microsomal N-hydroxylation of dapsone by cytochrome P-4503A4. Mol. Pharmacol. 41: 975-980
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 975-980
-
-
Fleming, C.M.1
Branch, R.A.2
Wilkinson, G.R.3
Guengerich, F.P.4
-
17
-
-
0020638672
-
Agranulcytosis associated with malaria prophylaxis with Maloprim
-
Friman, G., Nystrom-Rosander, C., Jonsell, G., Bjorkman, A., Lekas, G., Sendsrup, B. N. (1983) Agranulcytosis associated with malaria prophylaxis with Maloprim. Br. Med. J. 286: 1244-1245
-
(1983)
Br. Med. J.
, vol.286
, pp. 1244-1245
-
-
Friman, G.1
Nystrom-Rosander, C.2
Jonsell, G.3
Bjorkman, A.4
Lekas, G.5
Sendsrup, B.N.6
-
18
-
-
0025985781
-
Differential inhibition of individual human liver, cytochromes P-450 by cimetidine
-
Knodell, R. G., Browne, D. G., Gwozdz, G. P., Brian, W. R., Guengerich, F. P. (1991) Differential inhibition of individual human liver, cytochromes P-450 by cimetidine. Gastroenterology 101: 1680-1691
-
(1991)
Gastroenterology
, vol.101
, pp. 1680-1691
-
-
Knodell, R.G.1
Browne, D.G.2
Gwozdz, G.P.3
Brian, W.R.4
Guengerich, F.P.5
-
19
-
-
0015345305
-
Mechanism of methemoglobin formation by diphenylsulfones. Effect of 4-amino-4′-hydroxyaminodiphenylsulfone and other p-substituted derivatives
-
Kramer, P. A., Glader, B. E., Li, T. K. (1972) Mechanism of methemoglobin formation by diphenylsulfones. Effect of 4-amino-4′-hydroxyaminodiphenylsulfone and other p-substituted derivatives. Biochem. Pharmacol. 21: 1265-1274
-
(1972)
Biochem. Pharmacol.
, vol.21
, pp. 1265-1274
-
-
Kramer, P.A.1
Glader, B.E.2
Li, T.K.3
-
20
-
-
0024503778
-
Dapsone, trimethoprim and sulfamethizole plasma levels during treatment of pneumocystis pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)
-
Lee, B. L., Medina, I., Benowitz, N. L., Jacob, P., Wofsy, C. B., Mills, J. (1989) Dapsone, trimethoprim and sulfamethizole plasma levels during treatment of pneumocystis pneumonia in patients with the acquired immunodeficiency syndrome (AIDS). Ann. Intern. Med. 110: 606-611
-
(1989)
Ann. Intern. Med.
, vol.110
, pp. 606-611
-
-
Lee, B.L.1
Medina, I.2
Benowitz, N.L.3
Jacob, P.4
Wofsy, C.B.5
Mills, J.6
-
21
-
-
0014171067
-
The influence of anaesthetic agents on the formation of methaemoglobin induced by aniline in cats
-
McLean, S., Robinson, J., Starmer, G. A., Thomas, J. (1967) The influence of anaesthetic agents on the formation of methaemoglobin induced by aniline in cats. J. Pharm. Pharmacol. 19: 803-809
-
(1967)
J. Pharm. Pharmacol.
, vol.19
, pp. 803-809
-
-
McLean, S.1
Robinson, J.2
Starmer, G.A.3
Thomas, J.4
-
22
-
-
0022005835
-
Aminoglutethimide-induced haematologic toxicity: World-wide experience
-
Messeih, A. A., Lipton, A., Santen, R. J., Harvey, H. A., Boucher, A. E., Murray, R., Ragaz, J., Buzdar, A U., Nagel, G. A., Henderson, I. C. (1985) Aminoglutethimide-induced haematologic toxicity : world-wide experience. Cancer Treat. Reports 69: 1003-1004
-
(1985)
Cancer Treat. Reports
, vol.69
, pp. 1003-1004
-
-
Messeih, A.A.1
Lipton, A.2
Santen, R.J.3
Harvey, H.A.4
Boucher, A.E.5
Murray, R.6
Ragaz, J.7
Buzdar, A.U.8
Nagel, G.A.9
Henderson, I.C.10
-
23
-
-
0000622703
-
The carbon monoxide binding pigment of liver microsomes
-
Omura, T., Sato, R. (1964) The carbon monoxide binding pigment of liver microsomes. J. Biol. Chem. 221: 253-264
-
(1964)
J. Biol. Chem.
, vol.221
, pp. 253-264
-
-
Omura, T.1
Sato, R.2
-
24
-
-
0024245344
-
An in vitro study of the microsonal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin
-
Riley, R. J., Maggs, J. L., Lambert, C., Kitteringham, N. R., Park, B. K. (1988) An in vitro study of the microsonal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin. Br. J. Clin. Pharmacol. 26: 577-588
-
(1988)
Br. J. Clin. Pharmacol.
, vol.26
, pp. 577-588
-
-
Riley, R.J.1
Maggs, J.L.2
Lambert, C.3
Kitteringham, N.R.4
Park, B.K.5
-
25
-
-
0015879268
-
Propanil (3,4-dichloropro- Pionanilide)-induced methaemoglobin formation in mice in relation to acylamidase activity
-
Singleton, S. D., Murphy, S. D. (1973) Propanil (3,4-dichloropro-pionanilide)-induced methaemoglobin formation in mice in relation to acylamidase activity. Toxicol. Appl. Pharmacol. 25: 20-29
-
(1973)
Toxicol. Appl. Pharmacol.
, vol.25
, pp. 20-29
-
-
Singleton, S.D.1
Murphy, S.D.2
-
26
-
-
85058248410
-
Chemically induced methemoglobinemias in the mouse
-
Smith, R. P., Alkaitis, A. A., Schafer, P. R. (1967) Chemically induced methemoglobinemias in the mouse. Biochem. Pharmacol. 16: 317-328
-
(1967)
Biochem. Pharmacol.
, vol.16
, pp. 317-328
-
-
Smith, R.P.1
Alkaitis, A.A.2
Schafer, P.R.3
-
27
-
-
4444284036
-
-
Bridges J. W., Gorrod, J. W., Parke, D. V. (eds) Taylor and Francis, London
-
Uehleke, H. (1972) In: Bridges J. W., Gorrod, J. W., Parke, D. V. (eds) Biological Oxidation of Nitrogen in Organic Molecules. Taylor and Francis, London
-
(1972)
Biological Oxidation of Nitrogen in Organic Molecules
-
-
Uehleke, H.1
-
28
-
-
0026082128
-
Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes
-
Yamasaki, H., Degawn, M., Funae, Y., Imaoka, S., Inui, T., Guengerich, F. P. (1991) Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes. Carcinogenesis 12: 133-139
-
(1991)
Carcinogenesis
, vol.12
, pp. 133-139
-
-
Yamasaki, H.1
Degawn, M.2
Funae, Y.3
Imaoka, S.4
Inui, T.5
Guengerich, F.P.6
-
29
-
-
0022519155
-
Clinical Pharmacokinetics of dapsone
-
Zuidema, J., Hilbers-Modderman, E. S. M., Markus, F. W. H. M. (1986) Clinical Pharmacokinetics of dapsone. Clin. Pharmacokin. 11: 299-325
-
(1986)
Clin. Pharmacokin.
, vol.11
, pp. 299-325
-
-
Zuidema, J.1
Hilbers-Modderman, E.S.M.2
Markus, F.W.H.M.3
|