The duration of medium-chain triglyceride feeding determines brush border membrane lipid composition and hydrolase activity in newly weaned rats

Journal of Nutrition

Volumn 126, Issue 5, 1996, Pages 1455-1462

  Wang, Heng ^a   Dudley Jr , Alden W ^a   Dupont, Jacqueline ^b   Reeds, Peter J ^a   Hachey, David L ^a   Dudley, Mary A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

brush border hydrolases; long chain triglycerides; medium chain triglycerides; membrane lipid; rats

Indexed keywords

ALPHA GLUCOSIDASE; CHOLESTEROL; CYTOSOL AMINOPEPTIDASE; HYDROLASE; LONG CHAIN TRIACYLGLYCEROL; MEDIUM CHAIN TRIACYLGLYCEROL; MONOUNSATURATED FATTY ACID; OLIVE OIL; POLYUNSATURATED FATTY ACID; SOYBEAN OIL; SUCRASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTESTINE BRUSH BORDER; LIPID COMPOSITION; LIPID DIET; MALE; NONHUMAN; RAT;

EID: 0029870945     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/126.5.1455     Document Type: Article

References (29)

1. Bernard, A. & Carlier, H. (1991) Absorption and intestinal catabolism of fatty acids in the rat: effect of chain length and unsaturation. Exp. Physiol. 76: 446-455.
2. Bolin, T. D. (1971) Effect of diet on lactose activity in the rat. Gastroenterology 60: 432-437.
3. Brasitus, T. A. & Schachter, D. (1982) Cholesterol biosynthesis and modulation of membrane cholesterol and lipid dynamics in rat intestinal microvillus membranes. Biochemistry 21: 2241-2246.
4. Brasitus, T. A., Davidson, N. O. & Schachter, D. (1985) Variations in dietary triacylglycerol saturation alter the lipid composition and fluidity of rat small intestinal plasma membranes. Biochim. Biophys. Acta 812: 460-472.
5. Brasitus, T. A., Dudeja, P. K., Bolt, M.J.G., Sitrin, M. D. & Baum, C. (1989) Dietary triacylglycerol modulates sodium-dependent D-glucose transport, fluidity and fatty acid composition of rat small intestinal brush-border membrane. Biochim. Biophys. Acta 979: 177-186.
6. Chen, I. S., Subramaniam, S., Vahouny, G. V., Cassidy, M. M., Ikeda, I. & Kritchevsky, D. (1989) A comparison of the digestion and absorption of cocoa butter and palm kernel oil and their effects on cholesterol absorption in rats. J. Nutr. 119: 1569-1573.
7. Christon, R., Meslin, J. C., Thevenoux, J., Linard, A., Leger, C. L. & Delpal, S. (1991) Effects of a low dietary linoleic acid level on intestinal morphology and enterocyte brush border membrane lipid composition. Reprod. Nutr. Dev. 31: 691-701.
8. Dudley, M. A., Nichols, B. L., Rosenberger, J., Perkinson, J. S. & Reeds, P. J. (1992a) Feeding status affects in vivo prosucrase-isomaltase processing in rat jejunum. J. Nutr. 122: 528-534.
9. Dudley, M. A., Shulman, R. J., Reeds, P. J., Rosenberger, J., Putman, M., Johnston, P. K., Perkinson, J. S. & Nichols, B. N. (1992b) Developmental changes in lactase-phlorizin hydrolase precursor isoforms in the rat. J. Pediatr. Gastroenterol. Nutr. 15: 260-269.
10. Dudley, M. A., Wang, H., Hachey, D. L., Shulman, R. J., Perkinson, J. S., Rosenberger, J. & Mersmann, H. (1994) Jejunal brush border hydrolase activity is higher in tallow-fed than in corn oil-fed pigs. J. Nutr. 124: 1996-2005.
11. Dupont, J., White, P. J. & Feldman, E. B. (1991) Saturated and hydrogenated fats in food in relation to health. J. Am. Coll. Nutr. 10: 577-592.
12. Goldstein, R., Klein, T., Freier, S. & Menczel, J. (1971) Alkaline phosphatase and disaccharidase activities in the rat intestine from birth to weaning. I. Effect of diet on enzyme development. Am. J. Clin. Nutr. 24: 1224-1231.
13. Hamilton, J. G. & Comai, K. (1988) Rapid separation of neutral lipids, free fatty acids and polar lipids using prepacked silica Sep-Pak columns. Lipids 23: 1146-1149.
14. Henning, S. J. (1987) Functional development of the gastrointestinal tract. In: Physiology of the Gastrointestinal Tract (Leonard R. Johnson, ed.), pp. 285-300. Raven Press, NY.
15. Henning, S. J. & Leeper, L. L. (1982) Coordinate loss of glucocorticoid responsiveness by intestinal enzymes during postnatal development. Am. J. Physiol. 242: G89-G94.
16. Jeejeebhoy, K. N., Ahmad, S. & Kozak, G. (1970) Determination of fecal fats containing both medium and long chain triglycerides and fatty acids. Clin. Biochem. 3: 157-163.
17. Jensen, C. L., Hachey, D. L., Klein, P. D. & Heird, W. C. (1994) Effect of energy intake (EI) on oxidation of fatty acids (FA) by low birth weight (LBW) infants. Pediatr. Res. 35: 314A (abs.).
18. Lavau, M. M. & Hashim, S. A. (1978) Effect of medium chain triglycerides on lipogenesis and body fat in the rat. J. Nutr. 108: 613-620.
19. National Research Council (1985) Guide for the Care and Use of Laboratory Animals. Publication no. 85-23 (rev.). National Institutes of Health, Bethesda, MD.
20. Saito, M. (1972) Daily rhythmic changes in brush border enzymes of the small intestine and kidney in the rat. Biochim. Biophys. Acta 286: 212-215.
21. Sarda, P., Lepage, G., Roy, C. C. & Chessex, P. (1987) Storage of medium-chain triglycerides in adipose tissue of orally fed infants. Am. J. Clin. Nutr. 45: 399-405.
22. Shinohara, H., Goda, T., Takase, S. & Sugawa-Katayama, Y. (1993) Feeding medium-chain triglycerides to rats decreases degradation of sucrase-isomaltase complex in jejunum. J. Nutr. 123: 1161-1167.
23. Snedecor, G. W. & Cochran, W. G. (1980) Statistical Methods, pp. 234-235. The Iowa State University Press, Ames, IA.
24. Stenson, W. F., Seetharam, B., Talkad, V., Pickett, W., Dudeja, P. & Brasitus, T. A. (1989) Effects of dietary fish oil supplementation on membrane fluidity and enzyme activity in rat small intestine. Biochem. J. 263: 41-45.
25. Takase, S., & Goda, T. (1990) Effect of medium-chain triglycerides on brush border membrane-bound enzyme activity in rat small intestine. J. Nutr. 120: 969-976.
26. Thomson, A.B.R., Keelan, M., Cheng, T. & Clandinin, M. T. (1993) Delayed effects of early nutrition with cholesterol plus saturated or polyunsaturated fatty acids on intestinal morphology and transport function in the rat. Biochim. Biophys. Acta 1170: 80-91.
27. Thomson, A.B.R., Keelan, M., Clandinin, M. T. & Walker, K. (1986) Dietary fat selectively alters transport properties of rat jejunum. J. Clin. Invest. 77: 279-288.
28. Wang, H. & Gilles-Baillien, M. (1992) Alkaline phosphatase and ATPases in brush-border membranes of rat jejunum: distinct effects of divalent cations and of some inhibitors. Arch. Int. Physiol. Biochim. Biophys. 100: 289-294.
29. Wang, H., Hachey, D. L., Liu, D., Zhang, S. & Dudley, M. A. (1994) Microanalysis of cholesterol, phospholipid, medium- and long-chain fatty acids in biologic materials. Anal. Biochem. 218: 74-79.