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Volumn 33, Issue 2, 1996, Pages 171-178

Design and synthesis of a highly immunogenic, discontinuous epitope of HIV-1 gp120 which binds to CD4+ve transfected cells

Author keywords

discontinuous epitope; gp120; synthetic peptide

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN G; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE;

EID: 0029870362     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(95)00110-7     Document Type: Article
Times cited : (7)

References (23)
  • 1
    • 0026784923 scopus 로고
    • Crosslinking CD4 by human immunodeficiency virus gp120 primes T-cells for activation induced apoptosis
    • Banda N. K., Bernier J., Kurahara D. K., Kurrle R., Haigwood N., Sekaly R. P. and Finkel T. H. (1992) Crosslinking CD4 by human immunodeficiency virus gp120 primes T-cells for activation induced apoptosis. J. Exp. Med. 176, 1099-1106.
    • (1992) J. Exp. Med. , vol.176 , pp. 1099-1106
    • Banda, N.K.1    Bernier, J.2    Kurahara, D.K.3    Kurrle, R.4    Haigwood, N.5    Sekaly, R.P.6    Finkel, T.H.7
  • 2
    • 0025016461 scopus 로고
    • Antibody raised against soluble CD4-gp120 complex recognises the CD4 moiety and blocks membrane fusion without inhibiting CD4-gp120 binding
    • Celada F., Cambiaggi C., Maccari J., Burastero S., Gregory T., Patzer E., Porter J., McDanal C. and Matthews T. (1990) Antibody raised against soluble CD4-gp120 complex recognises the CD4 moiety and blocks membrane fusion without inhibiting CD4-gp120 binding. J. Exp. Med. 172, 1143-1150.
    • (1990) J. Exp. Med. , vol.172 , pp. 1143-1150
    • Celada, F.1    Cambiaggi, C.2    Maccari, J.3    Burastero, S.4    Gregory, T.5    Patzer, E.6    Porter, J.7    McDanal, C.8    Matthews, T.9
  • 4
    • 0022444429 scopus 로고
    • Protection of cattle against foot and mouth disease by a synthetic peptide
    • Dimarchi R., Brooke G., Gale C., Cracknell V., Doel T. and Mowat N. (1986) Protection of cattle against foot and mouth disease by a synthetic peptide. Science 232, 639-641.
    • (1986) Science , vol.232 , pp. 639-641
    • Dimarchi, R.1    Brooke, G.2    Gale, C.3    Cracknell, V.4    Doel, T.5    Mowat, N.6
  • 5
    • 0028109087 scopus 로고
    • Indirect mechanisms of HIV pathogenesis; how does it kill T cells
    • Finkel T. H. and Banda N. K. (1994) Indirect mechanisms of HIV pathogenesis; how does it kill T cells. Curr. Opin. Immun. 6, 605-615.
    • (1994) Curr. Opin. Immun. , vol.6 , pp. 605-615
    • Finkel, T.H.1    Banda, N.K.2
  • 7
    • 0026517545 scopus 로고
    • Activation induced death by apoptosis in CD4+ T-cells from human immunodeficiency virus infected asymptomatic individuals
    • Groux H., Monte D., Bourrez J. M., Capron A. and Ameisen J. C. (1992) Activation induced death by apoptosis in CD4+ T-cells from human immunodeficiency virus infected asymptomatic individuals. J. Exp. Med. 175, 331-340.
    • (1992) J. Exp. Med. , vol.175 , pp. 331-340
    • Groux, H.1    Monte, D.2    Bourrez, J.M.3    Capron, A.4    Ameisen, J.C.5
  • 8
    • 0000448982 scopus 로고
    • Prediction of protein antigenic determinants from amino acid sequences
    • Hopp T. P. and Woods K. R. (1981) Prediction of protein antigenic determinants from amino acid sequences. Proc. natn. Acad. Sci. USA 78, 3824-3828.
    • (1981) Proc. Natn. Acad. Sci. USA , vol.78 , pp. 3824-3828
    • Hopp, T.P.1    Woods, K.R.2
  • 10
    • 0023651341 scopus 로고
    • Delineation of a region of the human immunodeficiency virus type 1 critical for interaction with the CD4 receptor
    • Lasky L. A., Nakamura G., Smith D. H., Fennie C., Shimasaki C., Patzer E., Berman P., Gregory T. and Capon D. J. (1987) Delineation of a region of the human immunodeficiency virus type 1 critical for interaction with the CD4 receptor. Cell 50, 975-985.
    • (1987) Cell , vol.50 , pp. 975-985
    • Lasky, L.A.1    Nakamura, G.2    Smith, D.H.3    Fennie, C.4    Shimasaki, C.5    Patzer, E.6    Berman, P.7    Gregory, T.8    Capon, D.J.9
  • 11
    • 0025292252 scopus 로고
    • Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells
    • Leonard C. K., Spellman W. M., Riddle L., Harris R. J., Thomas N. J. and Gregory T. J. (1990) Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J. Biol. Chem. 265, 10,373-10,382.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10373-10382
    • Leonard, C.K.1    Spellman, W.M.2    Riddle, L.3    Harris, R.J.4    Thomas, N.J.5    Gregory, T.J.6
  • 12
    • 0022587282 scopus 로고
    • Binding of HTLV-III/LAV to T4+ T-cells by a complex of the 110K viral protein and the T4 molecule
    • McDougal J. S., Kennedy M. S., Sligh J. M., Cort S. P., Mawle A. and Nicholson J. K. A. (1986) Binding of HTLV-III/LAV to T4+ T-cells by a complex of the 110K viral protein and the T4 molecule. Science 231, 382-385.
    • (1986) Science , vol.231 , pp. 382-385
    • McDougal, J.S.1    Kennedy, M.S.2    Sligh, J.M.3    Cort, S.P.4    Mawle, A.5    Nicholson, J.K.A.6
  • 13
  • 14
    • 0023107134 scopus 로고
    • Computer assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: Prediction of antigenic epitopes in conserved and variable regions
    • Modrow S., Hahn B. H., Shaw G. M., Gallo R. C., Wong-Staal F. and Wolf H. (1987) Computer assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions. J. Virol. 61, 570-578.
    • (1987) J. Virol. , vol.61 , pp. 570-578
    • Modrow, S.1    Hahn, B.H.2    Shaw, G.M.3    Gallo, R.C.4    Wong-Staal, F.5    Wolf, H.6
  • 15
    • 0025253819 scopus 로고
    • Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
    • Olshevsky U., Helseth E., Furman F., Haseltine W. and Sodroski J. (1990) Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding. J. Virol. 64, 5701-5707.
    • (1990) J. Virol. , vol.64 , pp. 5701-5707
    • Olshevsky, U.1    Helseth, E.2    Furman, F.3    Haseltine, W.4    Sodroski, J.5
  • 16
    • 0026567492 scopus 로고
    • Truncated variants of gp120 bind CD4 with high affinity and suggest a minimum CD4 binding region
    • Pollard S. R., Rosa M. D., Rosa J. J. and Wiley D. C. (1992) Truncated variants of gp120 bind CD4 with high affinity and suggest a minimum CD4 binding region. EMBO J. 11, 585-591.
    • (1992) EMBO J. , vol.11 , pp. 585-591
    • Pollard, S.R.1    Rosa, M.D.2    Rosa, J.J.3    Wiley, D.C.4
  • 17
    • 0343080386 scopus 로고
    • OKT-4 antigen bearing molecule is a receptor for the human retrovirus HTLV-III
    • Popovic M., Gallo R. C. and Mann D. L. (1985) OKT-4 antigen bearing molecule is a receptor for the human retrovirus HTLV-III. Clin. Res. 33, 560.
    • (1985) Clin. Res. , vol.33 , pp. 560
    • Popovic, M.1    Gallo, R.C.2    Mann, D.L.3
  • 18
    • 0019873820 scopus 로고
    • Estimation of globular protein secondary structure from circular dichroism
    • Provencher S. W. and Glockner J. (1981) Estimation of globular protein secondary structure from circular dichroism. Biochemistry 20, 33-37.
    • (1981) Biochemistry , vol.20 , pp. 33-37
    • Provencher, S.W.1    Glockner, J.2
  • 19
    • 37049066619 scopus 로고
    • Peptide synthesis: Synthesis of the cysteine-containing peptides of biological and pharmaceutical interest, α-h-ANF and h-big endothelin
    • Ramage R. and Stewart A. S. J. (1993) Peptide synthesis: synthesis of the cysteine-containing peptides of biological and pharmaceutical interest, α-h-ANF and h-big endothelin. J. Chem. Soc. Perk. Trans. I 17, 1947-1952.
    • (1993) J. Chem. Soc. Perk. Trans. I , vol.17 , pp. 1947-1952
    • Ramage, R.1    Stewart, A.S.J.2
  • 20
    • 0028268603 scopus 로고
    • Synthetic, structural and biological studies of the ubiquitin system; the total chemical synthesis of ubiquitin
    • Ramage R., Green J., Muir T. W., Ogunjobi O. M., Love S. and Shaw K. (1994) Synthetic, structural and biological studies of the ubiquitin system; the total chemical synthesis of ubiquitin. Biochem. J. 299, 151-158.
    • (1994) Biochem. J. , vol.299 , pp. 151-158
    • Ramage, R.1    Green, J.2    Muir, T.W.3    Ogunjobi, O.M.4    Love, S.5    Shaw, K.6
  • 21
    • 0027321334 scopus 로고
    • Primary structural elements responsible for the conformational switch in the envelope glycoprotein gp120 from human immunodeficiency virus type 1: LPCR is a motif governing folding
    • Reed J. and Kinzel V. (1993) Primary structural elements responsible for the conformational switch in the envelope glycoprotein gp120 from human immunodeficiency virus type 1: LPCR is a motif governing folding. Proc. natn. Acad. Sci. USA 90, 6761-6765.
    • (1993) Proc. Natn. Acad. Sci. USA , vol.90 , pp. 6761-6765
    • Reed, J.1    Kinzel, V.2
  • 22
    • 0028017515 scopus 로고
    • Inhibitors of the conformational switch involved in CD4 binding by the env glycoprotein gp120 from the human immunodeficiency virus type 1 (HIV1)
    • Reed J. and Kinzel V. (1994) Inhibitors of the conformational switch involved in CD4 binding by the env glycoprotein gp120 from the human immunodeficiency virus type 1 (HIV1). Biochemistry 33, 10993-10998.
    • (1994) Biochemistry , vol.33 , pp. 10993-10998
    • Reed, J.1    Kinzel, V.2
  • 23
    • 0025866185 scopus 로고
    • Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding
    • Sattentau Q. J. and Moore J. P. (1991) Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding. J. Exp. Med. 174, 407-415.
    • (1991) J. Exp. Med. , vol.174 , pp. 407-415
    • Sattentau, Q.J.1    Moore, J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.