Preservation of endothelium-dependent relaxation in cholesterol-fed and streptozotocin-induced diabetic mice by the chronic administration of cholestyramine

British Journal of Pharmacology

Volumn 118, Issue 2, 1996, Pages 385-391

  Kamata, Katsuo ^a   Sugiura, Makoto ^a   Kojima, Satoshi ^a   Kasuya, Yutaka ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

A23187; Cholesterolaemia; Cholestyramine; Diabetic mouse; Endothelium; LDL; Streptozotocin

Indexed keywords

ACETYLCHOLINE; CALCIMYCIN; CHOLESTEROL; COLESTYRAMINE; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM; LIPOPROTEIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0029870233     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15414.x     Document Type: Article

References (58)

1. ABIRU, T., KAMATA, K. & KASUYA, Y. (1991). Effects of chronic diabetes on vascular responses of basilar artery and aorta from rabbits with alloxan-induced diabetes. Res. Commun. Chem. Pathol. Pharmacol., 74, 71-87.
2. ABIRU, T., KAMATA, K., MIYATA, N. & KASUYA, Y. (1990a). Differences in vascular responses to vasoactive agents of basilar artery and aorta from rabbits with alloxan-induced diabetes. Can. J. Physiol. Pharmacol., 68, 882-888.
3. ABIRU, T., WATANABE, Y., KAMATA, K. & KASUYA, Y. (1993). Changes in endothelium-dependent relaxation and levels of cyclic nucleotides in the perfused mesenteric arterial bed from streptozotocin-induced diabetic rats. Life Sci., 53, PL7-PL12.
4. ABIRU, T., WATANABE, Y., KAMATA, K., MIYATA, N. & KASUYA, Y. (1990b). Decrease in endothelium-dependent relaxation and levels of cyclic nucleotides in aorta from rabbits with alloxan-induced diabetes. Res. Commun. Chem. Pathol. Pharmacol., 68, 13-25.
5. AGRAWAL, D.K. & MCNEILL, J.H. (1987). Vascular responses to agonists in rat mesenteric artery from diabetic rats. Can. J. Physiol. Pharmacol., 65, 1484-1490.
6. BERLINER, J.A., TERRITO, M.C., SEVANIAN, A., RAMIN, S., KIM, J.Ai., BAMSHAD, B., ESTERSON, M. & FOGELMAN, A.M. (1990). Minimally modified low density lipoprotein stimulates monocyte endothelial interaction. J. Clin. Invest., 85, 1260-1267.
7. BOSSALLER, C., HABIB, G.B., YAMAMOTO, H. WILLIAMS, C., WELLS, W. & HENRY, P.D. (1987). Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 3′, 5′-monophosphate formation in the atherosclerotic human coronary artery and rabbit aorta. J. Clin. Invest., 79, 170-174.
8. CHRISTRIEB, A.R. (1973). Diabetes and hypertensive vascular disease. Mechanism and treatment. Am. J. Cardiol., 32, 592-606.
9. DICORLETO, P.E. & CHISOLM, G.M. (1986). Participation of the endothelium in the development of the atherosclerosis plaque. Prog. Lipid Res., 25, 365-374.
10. DUBOWSKI, K.M. (1962). An o-toluidine method for body-fluid glucose determination. Clin. Chem., 8, 214-235.
11. DURANTE, W., SEN, A.K. & SUNAHARA, F.A. (1988). Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats. Br. J. Pharmacol., 94, 463-468.
12. FLAVAHAN, N.A. (1992). Atherosclerosis or lipoprotein-induced endothelial dysfunction: potential mechanisms underlying reduction in EDRF/nitric oxide activity. Circulation, 85, 1927-1937.
13. FLAVAHAN, N.A. (1993). Lysophosphatidylcholine modifies G protein-dependent signaling in porcine endothelial cells. Am. J. Physiol., 264, H722-H727.
14. FORSTERMANN, U., MAGGE, A., ALHEID, U., HAVERICH, A. & FROLICH, J.C. (1988). Selective attenuation of endothelium-mediated vasodilatation in atherosclerotic human coronary arteries. Circ. Res., 62, 185-190.
15. FREIMAN, R.C., MITCHELL, G.G., HEISTAD, D.D., ARMSTRONG, M.I. & HARRISON, D.G. (1986). Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates. Circ. Res., 58, 783-789.
16. GRUNDY, S.M., SCHROTT, H.G., HAZZARD, W.R., BIERMAN, E.L. & MOTULSKY, A.G. (1971). Interaction of the enterohepatic circulation of bile acids in man; comparative effects of cholestyramine and ileal exclusion on cholesterol metabolism. J. Lab. Clin. Med., 78, 94-121.
17. HABIB, J.B., BOSSALLER, C., WELLS, C., MORRISSETT, J.D. & HENRY, P.D. (1986). Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110. Circ. Res., 58, 305-309.
18. HARRIS, K.H. & MACLEOD, K.M. (1988). Influence of the endothelium on contractile responses of arteries from diabetic rats. Eur. J. Pharmacol., 153, 55-64.
19. HATTORI, Y., KAWASAKI, H., ABE, K. & KANNO, M. (1991). Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta. Am. J. Physiol., 261, H1086-H1094.
20. JACOB, M., PLANE, F. & BRUCKDORFER, K.R. (1990). Native and oxidized low-density lipoproteins have different inhibitory effects on endothelium-derived relaxing factor in the rabbit aorta. Br. J. Pharmacol., 100, 21-26.
21. JOYKODY, L., SENARINE, M., THOMOSON, A. & KAPPAGODA, T. (1987). Endothelium-dependent relaxation in experimental atherosclerosis in the rabbit. Circ. Res., 60, 251-264.
22. KAMATA, K., KOJIMA, S., SUGIURA, M. & KASUYA, Y. (1996). Preservation of endothelium-dependent vascular relaxation in cholesterol-fed mice by the chronic administration of prazosin or pravastatin. Jpn. J. Pharmacol., 70, 149-156.
23. KAMATA, K., MIYATA, N., ABIRU, T. & KASUYA, Y. (1992). Functional changes in vascular smooth muscle and endothelium of arteries during diabetes mellitus. Life Sci., 50, 1379-1387.
24. KAMATA, K., MIYATA, N. & KASUYA, Y. (1989a). Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats. Br. J. Pharmacol., 97, 614-618.
25. KAMATA, K., MIYATA, N. & KASUYA, Y. (1989b). Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats. J. Pharmacol. Exp. Ther., 249, 890-894.
26. KOVANEN, P.T., BILHEIMER, D.W., GOLDSTEIN, J.L., JARAMILLO, J.J. & BROWN, M.S. (1981). Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog. Proc. Natl. Acad. Sci. U.S.A., 78, 1194-1198.
27. KUGIYAMA, K., KERNS, S.A., MORRISETT, J.D., ROBERTS, R. & HENRY, P.D. (1990). Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature, 344, 160-162.
28. KUGIYAMA, K., OHGUSHI, M., SUGIYAMA, MUROHARA, T., FUKUNAGA, K., MIYAMOTO, E. & YASUE, H. (1992). Lysophosphatidylcholine inhibits surface receptor-mediated intracellular signals in endothelial cells by a pathway involving protein kinase C activation. Circ. Res., 71, 1422-1428.
29. LANGENSTROER, P. & PIEPER, G.M. (1992). Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am. J. Physiol., 263, H257-H265.
30. LUNDER, P.I., SELWYN, A.P., SHOOK, T.I. WAYNE, R.R. & MUDGE, G.H. (1986). Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N. Engl. J. Med., 315, 1046-1050.
31. MERAJI, S., JOYKODY, L., SENARANTNE, M.P., THOMSON, A.B.R. & KAPPAGODA, T. (1987). Endothelium-dependent relaxation in aorta of BB rat. Diabetes, 36, 978-981.
32. MIYATA, N., TSUCHIDA, K., OKUYAMA, S., OTOMO, S., KAMATA, K. & KASUYA, Y. (1992). Age-related changes in endothelium-dependent relaxation in aorta from genetically dibetic WBN/Kob rats. Am. J. Physiol., 262, H1104-H1109.
33. MIYATA, N., YAMAURA, H., TSUCHIDA, K., OKUYAMA, S., OTOMOTO, S., KAMATA, K. & KASUYA, Y. (1993). Impairment of endothelium-dependent relaxation of superior mesenteric artery in genetically diabetic WBN/Kob rats. Can. J. Physiol. Pharmacol., 71, 297-300.
34. OYAMA, Y., KAWASAKI, H., HATTORI, Y. & KANNO, M. (1986). Attenuation of endothelium-dependent relaxation in aorta from diabetic rats. Eur. J. Pharmacol., 132, 75-78.
35. PIEPER, G.M. & GROSS, G.J. (1988). Oxygen free radical abolish endothelium-dependent relaxation in diabetic rat aorta. Am. J. Physiol., 255, H825-H833.
36. PIEPER, G.M., LANGENSTROER, P. & GROSS, G.J. (1993). Hydroxy radicals mediate injury to endothelium-dependent relaxation in diabetic rats. Mol. Cell. Biochem., 122, 139-145.
37. PIEPER, G.M., MEI, D.A., LANGENSTROER, P. & O'ROURKE, S.T. (1992). Bioassay of endothelium-derived relaxing factor in diabetic rat aorta. Am. J. Physiol., 263, H676-H680.
38. POSTON, L. & TAYLOR, P.D. (1995). Endothelium-mediated vascular function in insulin-dependent diabetes mellitus. Clin. Sci., 88, 245-255.
39. QUINN, M.T., PARTHASARATHY, S., FONG, L.G. & STEINBERG, D. (1987). Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc. Natl. Acad. Sci. U.S.A., 84, 2995-2998.
40. RAJAVASHISTH, T.A., ANDALIBI, A., TERRITO, M.C., BERLINER, J.A., NAVAB, M., FOGELMAN, M.A. & LUSIS, A.J. (1990). Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature, 344, 254-257.
41. ROSS, R. (1986). The pathogenesis of atherosclerosis: an update. N. Engl. J. Med., 314, 488-500.
42. SHEPHERD, J., PACKARD, C.J., BICKER, S., LAWRIE, T.D.V. & MORGAN, H.G. (1980). Cholestyramine promotes receptor-mediated low-density-lipoprotein catabolism. N. Engl. J. Med., 302, 1219-1222.
43. SHIMOKAWA, H. & VANHOUTTE, P.M. (1989). Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis. Circ. Res., 64, 900-914.
44. SIMON, B.C., CUNNINGHAM, L.D. & COHEN, R.A. (1990). Oxidized low density lipoprotein inhibit endothelium-dependent relaxations in the pig coronary artery. FASEB J., 4, A314.
45. SIMON, B.C., HAUDENSCHILD, C.C. & COHEN, R.A. (1993). Preservation of endothelium-dependent relaxation in atherosclerotic rabbit aorta by probucol. J. Cardiovasc. Pharmacol., 21, 893-901.
46. STEINBERG, U.P., PARTHASARATHY, S., CAREW, T.E., KHOO, J.C. & WITZTUM, J.L. (1989). Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogeicity. N. Engl. J. Med., 320, 915-924.
47. STEINBERG, U.P., PARTHASARATHY, S., LEAKE, D.S., WITZUM, J.L. & STEINBERG, G.D. (1984). Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc. Natl. Acad. Sci. U.S.A., 81, 3883-3887.
48. STEINBRECHER, U.P., PARTHASARRATHY, S., LEAKE, D.S., WITZTUM, J.L. & STEINBERG, D. (1984). Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc. Natl. Acad. Sci. U.S.A., 81, 3883-3887.
49. SUGIYAMA, S., KUGIYAMA, K., OHGUSHI, M., FUJIMOTO, K. & YASUE, H. (1994). Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leukocyte-induced endothelial dysfunction in porcine coronary arteries. Role of protein kinase C. Circ. Res., 74, 565-575.
50. TAYLOR, P.D., MACARTHY, A.L., THOMAS, C.R. & POSTON, L. (1992). Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric arteries of streptozotocin-induced diabetic rats. Br. J. Pharmacol., 107, 393-399.
51. TAYLOR, P.D., OON, B.B., THOMAS, C.R. & POSTON, L. (1994a). Prevention by insulin treatment of endothelial dysfunction but not enhanced noradrenaline-induced contractility in nesenteric resistance arteries from streptozotocin-induced diabetic rats. Br. J. Pharmacol., 111, 35-41.
52. TAYLOR, P.D., WICKENDEN, A.D., MIRRLEES, D.J. & POSTON, L. (1994b). Endothelial function in the isolated perfused mesentery and aortae of rats with streptozotocin-induced diabetes: effects of treatment with the aldose reductase inhibitor, ponalrestat. Br. J. Pharmacol., 111, 42-48.
53. 2. Am. J. Physiol., 257, H1327-H1333.
54. VERBEUREN, T.J., JORDENS, F.H., ZONNEKEYN, L.L., VANHOVE, C.E., COENE, M.C. & HERMAN, A.G. (1986). Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits. Circ. Res., 58, 552-564.
55. WITZTUM, J.L. & STEINBER, G.D. (1991). Role of oxidized low density lipoprotein in atherosclerosis. J. Clin. Invest., 88, 1785-1792.
56. YAMAMOTO, Y., TOMOIKE, H., EGASHIRA, K. & NAKAMURA, M. (1987). Attenuation of endothelium-related relaxation and enhanced responsiveness of vascular smooth muscle to histamine in spastic coronary arterial segments from miniature pigs. Circ. Res., 61, 772-778.
57. YASUE, H., MATSUYAMA, K., MATSUYAMA, K., OKUMURA, K., MORIGAMI, Y. & OGAWA, H. (1990). Response of angiographically normal human coronary arteries to intracoronary injection of acetylcholine by age and segment: possible role of early coronary atherosclerosis. Circulation, 81, 482-490.
58. YOKOYAMA, M., HIRATA, K., MIYAKE, R., AKITA, H., ISHIKAWA, Y. & FUKUZAKI, H. (1990). Lysophosphoatidylcholine: essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low-density lipoprotein. Biochem. Biophys. Res. Commun., 168, 301-308.