Engineering a mineralocorticoid- to a glucocorticoid-synthesizing cytochrome P450

Journal of Biological Chemistry

Volumn 271, Issue 14, 1996, Pages 8028-8033

  Böttneri, Benjamin ^a   Schrauber, Hannelore ^a   Bernhardt, Rita ^a,b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GLUCOCORTICOID; MINERALOCORTICOID;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; GENE SWITCHING; GENETIC ENGINEERING; HYDROXYLATION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; STEROID METABOLISM; ZONA GLOMERULOSA;

ALDOSTERONE SYNTHASE; AMINO ACID SEQUENCE; BASE SEQUENCE; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STEROID 11-BETA-HYDROXYLASE; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0029870185     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.14.8028     Document Type: Article

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