Two distinct pathways for histamine H2 receptor down-regulation: H2 Leu124 → Ala receptor mutant provides evidence for a cAMP-independent action of H2 agonists

Journal of Biological Chemistry

Volumn 271, Issue 13, 1996, Pages 7574-7582

  Smit, Martine J ^a   Roovers, Edwin ^a   Timmerman, Henk ^a   Van De Vrede, Yvonne ^a   Alewijnse, Astrid E ^a   Leurs, Rob ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CRICETINAE; CRICETULUS GRISEUS;

HISTAMINE H2 RECEPTOR;

ANIMAL CELL; ARTICLE; CHO CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; RNA ANALYSIS; SITE DIRECTED MUTAGENESIS;

1-METHYL-3-ISOBUTYLXANTHINE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHO CELLS; CHOLERA TOXIN; CRICETINAE; CYCLIC AMP; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FORSKOLIN; GENE EXPRESSION; GUANIDINES; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE H2 ANTAGONISTS; IODINE RADIOISOTOPES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, SECONDARY; RADIOLIGAND ASSAY; RATS; RECEPTORS, HISTAMINE H2; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSFECTION;

EID: 0029869827     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.13.7574     Document Type: Article

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