Activity of 2-azaspiro[4.5]decane-6-carboxylates as GABA-uptake inhibitors

Archiv der Pharmazie

Volumn 329, Issue 3, 1996, Pages 149-154

  Fleischhacker, Wilhelm ^a   Lauritz, Silvia ^a   Urban, Ernst ^a   Baumann, Peter ^b   Bittiger, Helmut ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b CIBA GEIGY LTD   (Switzerland)

Author keywords

GABA uptake inhibitors; spirocyclic amino acid esters; structure activity relationships

Indexed keywords

2 AZASPIRO [4.5] DECANE 6 CARBOXYLIC ACID DERIVATIVE; 3 AMINOPROPANEPHOSPHINIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; AMINO ACID DERIVATIVE; MUSCIMOL; NIPECOTIC ACID; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; NEUROTRANSMITTER UPTAKE INHIBITORS; RATS; RECEPTORS, GABA-A; RECEPTORS, GABA-B; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029869809     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19963290307     Document Type: Article

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