The processing proteases prohormone thiol protease, PC1/3 and PC2, and 70-kDa aspartic proteinase show preferences among proenkephalin, proneuropeptide Y, and proopiomelanocortin substrates

Archives of Biochemistry and Biophysics

Volumn 328, Issue 1, 1996, Pages 107-114

  Hook, Vivian Y H ^a,b   Schiller, Martin R ^c   Azaryan, Anahit V ^c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UCSD MEDICAL CENTER   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; CYSTEINE PROTEINASE; HORMONE PRECURSOR; NEUROPEPTIDE Y; PEPTIDE HORMONE; PROENKEPHALIN; PROOPIOMELANOCORTIN; PROTEINASE; RECOMBINANT PROTEIN; SUBTILISIN; THIOL PROTEINASE;

ARTICLE; CATTLE; CHROMAFFIN GRANULE; ENZYME PURIFICATION; ENZYME SUBSTRATE; ESCHERICHIA COLI; HORMONE SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; SECRETORY GRANULE;

ANIMALS; ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; CATTLE; CHROMAFFIN GRANULES; CYSTEINE ENDOPEPTIDASES; ENKEPHALINS; MOLECULAR SEQUENCE DATA; NEUROPEPTIDE Y; PRO-OPIOMELANOCORTIN; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASES; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SUBTILISINS;

BOS TAURUS; ESCHERICHIA COLI;

EID: 0029869662     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0149     Document Type: Article

References (34)

1. Hook, V. Y. H., Azaryan, A. V., Hwang, S. R., and Tezapsidis, N. (1994) FASEB J. 8, 1269-1278.
2. Steiner, D. F., Smeekens, S. P., Ohagi, S., and Chan, S. F. (1992) J. Biol. Chem. 267, 23435-23438.
3. Loh, Y. P., Beinfeld, M. C., and Birch, N. P. (1993) in Mechanisms of Intracellular Trafficking and Processing of Proproteins (Loh, Y. P., Ed.), pp. 179-224, CRC Press, Boca Raton, FL.
4. Krieger, T. K., and Hook, V. Y. H. (1991) J. Biol. Chem. 266, 8376-8383.
5. Azaryan, A. V., and Hook, V. Y. H. (1994) FEBS Lett. 341, 197-202.
6. Azaryan, A. V., and Hook, V. Y. H. (1994) Arch. Biochem. Biophys. 314, 171-177.
7. Schiller, M. R., Mende-Mueller, L., Moran, K., Meng, M., Miller, K. W., and Hook, V. Y. H. (1995) Biochemistry 34, 7988-7995.
8. Azaryan, A. V., Schiller, M., Mende-Mueller, L., and Hook, V. Y. H. (1995) J. Neurochem. 65, 1771-1779.
9. Azaryan, A. V., Krieger, T. J., and Hook, V. Y. H. (1995) J. Biol. Chem. 270, 8201-8208.
10. Christie, D. L., Batchelor, D. C., and Palmer, D. J. (1991) J. Biol. Chem. 266, 15679-15683.
11. Kirchmair, R., Gee, P., Hogue-Angeletti, R., Laslop, A., Fischer-Colbrie, R., and Winkler, H. (1992) FEBS Lett. 297, 302-305.
12. Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Budendorff, J. W. (1990) Methods Enzymol. 185, 60-89.
13. Tezapsidis, N., Noctor, S., Kannan, R., Krieger, T. J., Mende-Mueller, L., and Hook, V. Y. H. (1995) J. Biol. Chem. 270, 13285-13290.
14. Loh, Y. P., Parish, D. C., and Tuteja, R. (1985) J. Biol. Chem. 260, 7194-7205.
15. Estivariz, F. E., Friedman, T. C., Chikuma, T., and Loh, Y. P. (1992) J. Biol. Chem. 267, 7456-7463.
16. Bennet, D. L., Bailyes, E., Nielsen, E., Guest, P. C., Rutherford, N. G., Arden, S. D., and Hutton, J. C. (1992) J. Biol. Chem. 267, 15229-15236.
17. Bailyes, E. M., Shennan, K. I. J., Seal, A. J., Smeekens, S. P., Steiner, D. F., Hutton, J. C., and Docherty, K. (1992) Biochem. J. 285, 391-394.
18. Stern, A. S., Lewis, R. C., Kimura, S., Kilpatrrick, K. D., Jones, B. N., Kojima, K., and Stein, S. (1980) in Biosynthesis, Modification, and Processing of Cellular and Viral Polypeptides (Blough, H. A., and Tiffany, J. M., Eds.), pp. 99-100, Academic Press, New York.
19. Carmichael, W. S., Stoddard, S. L., O'Connor, D. T., Yaksh, T. L., and Tyce, G. M. (1990) Neuroscience 34, 433-440.
20. Yoshikawa, K., Williams, C., and Sabol, S. L. (1984) J. Biol. Chem. 259, 309-314.
21. Higuchi, H., Yang, H. Y. T., and Sabol, S. L. (1988) J. Biol. Chem. 263, 6288-6295.
22. Boileau, G., Barbeau, C., Jeannotte, L., Chretien, M., and Drouin, J. (1983) Nucleic Acids Res. 11, 8063-8071.
23. Hwang, S. R., Kohn, A. B., and Hook, V. Y. H. (1994) Proc. Natl. Acad. Sci. USA 91, 9570-9583.
24. Chevrier, D., Lemieux, E., Fyfe, M., Labonte, N., Zollinger, M., Bennet, H. P. J., and Crine, P. (1991) Biochem. Cell. Biol. 69, 58-65.
25. Ungar, A., and Phillips, J. H. (1983) Physiol. Rev. 63, 787-843.
26. Gainer, H., Russell, J. T., and Loh, Y. P. (1985) Neuroendocrinology 40, 171-184.
27. Hook, V. Y. H., Purviance, R. T., Azaryan, A. V., Hubbard, G., and Krieger, T. K. (1993) J. Biol. Chem. 268, 20570-20577.
28. Hwang, S. R., Kohn, A. B., and Hook, V. Y. H. (1995) FEBS Lett. 368, 471-476.
29. Krieger, T. J., Mende-Mueller, L., and Hook, V. Y. H. (1992) J. Neurochem. 59, 26-31.
30. Schiller, M. R., Kohn, A. B., Mende-Mueller, L. M., Miller, K., and Hook, V. Y. H. (1996) FEBS Lett., in press.
31. Azaryan, A. V., Schiller, M. R., and Hook, V. Y. H. (1995) Biochem. Biophys. Res. Commun. 215, 937-944.
32. Benjannet, S., Rondeau, N., Day, R., Chretien, M., and Seidah, N. G. (1991) Proc. Natl. Acad. Sci. USA 88, 3564-3568.
33. Thomas, L., Leduc, R., Thorne, B. A., Smeekens, S. P., Steiner, D. F., and Thomas, G. (1991) Proc. Natl. Acad. Sci. USA 88, 5297-5301.
34. Breslin, M. B., Lindberg, I., Benjannet, S., Mathis, J. P., Lazure, C., and Seidah, N. G. (1993) J. Biol. Chem. 36, 27084-27093.