Antenatal phenobarbital therapy and neonatal outcome I: Effect on intracranial hemorrhage

Pediatrics

Volumn 97, Issue 5, 1996, Pages 644-648

  Shankaran, Seetha ^a,b   Cepeda, Eugene ^a   Muran, Geraldine ^a   Mariona, Federico ^a   Johnson, Samuel ^a   Kazzi, S Nadya ^a   Poland, Ronald ^a   Bedard, Mary P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

Author keywords

antenatal phenobarbital therapy; neonatal intracranial hemorrhage

Indexed keywords

PHENOBARBITAL;

ADULT; ARTICLE; BRAIN HEMORRHAGE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG SCREENING; FEMALE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NEWBORN; PREMATURITY; PRENATAL CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; ANTICONVULSANTS; BIRTH WEIGHT; CEREBRAL HEMORRHAGE; FEMALE; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INJECTIONS, INTRAVENOUS; MATERNAL-FETAL EXCHANGE; OBSTETRIC LABOR, PREMATURE; PATIENT DISCHARGE; PHENOBARBITAL; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY, MULTIPLE; PROSPECTIVE STUDIES; QUADRUPLETS; TRIPLETS; TWINS;

EID: 0029869585     PISSN: 00314005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Shankaran S, Cepeda EE, Ilagan N, et al. Antenatal phnobarbital for the prevention of neonatal intracerebral hemorrhage. Am J Obstet Gynecol. 1986;154:53-57
2. Morales WJ, Koerten J. Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital. Obstet Gynecol. 1986;68:295-299
3. DeCarolis S, DeCarolis MP, Caruso A, et al. Antenatal phenobarbital in preventing intraventricular hemorrhage in premature newborns. Fetal Ther. 1988;3:224-229
4. Kaempf JW, Porreco R, Molina R, Hale K, Pantoja AF, Rosenberg AA. Antenatal phenobarbital for the prevention of periventricular and intraventricular hemorrhage: a double-blind, randomized, placebo-controlled, multihospital trial. J Pediatr. 1990;117:933-938
5. Horbar JD. Prevention of periventricular-intraventricular hemorrhage. In: Sinclair JC, Bracken MB, eds. Effective Care of the Newborn Infant. New York, NY: Oxford University Press; 1992:562-589
6. Shankaran S, Cepeda EE, Ilagan N, Kauffman RE. Pharmacokinetic basis for antenatal dosing of phenobarbital for the prevention of neonatal intracerebral hemorrhage. Dev Pharmacol Ther. 1986;9:171-177
7. Shankaran S, Slovis TLS, Bedard MP, Poland RL. Sonographic classification of intracranial hemorrhage: a prognostic indicator of mortality, morbidity and short-term neurologic outcome. J Pediatr. 1982;100: 469-475
8. Valaes TN, Harvey-Wilkes K, Pharmacologic approaches to the prevention and treatment of neonatal hyperbilirubinemia. Clin Perinatol. 1990; 17:245-273
9. Shankaran S, Woldt E, Nelson J, Bedard M, Delaney-Black V Antenatal phenobarbital therapy and neonatal outcome II: neurodevelopmental outcome at 36 months. Pediatrics. 1996;27:649-652
10. SPSS, Inc. Statistical Package for the Social Services. Version 6.1 Chicago, IL: SPSS, Inc; 1994
11. Crowley P, Chalmers I, Keirse MJNC The effect of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. Br J Obstet Gynecol 1990;97:11-25
12. Garite TJ, Rumney RJ, Briggs GG, et al A randomized, placebo-controlled trial of betamethasome for the prevention of respiratory distress syndrome at 24 to 28 weeks' gestation. Am J Obstet Gynecol. 1992;166:646-651
13. Maher JE, Cliver SP, Goldenberg RL, Davis RO, Copper RL, March of Dimes Multicenter Trial Group. The effect of corticosteroid therapy in the very premature infant. Am J Obstet Gynecol. 1994;170:869-873
14. Shankaran S, Bauer CR, Bain R, Wright LL, Zachary J. The relationship between antenatal steroid administration and grade III-IV intracranial hemorrhage in low birth weight infants. Am J Obstet Gynecol. 1995;173: 305-312
15. Norton ME, Merrill J, Cooper BAB, Kuller JA, Clyman RI. Neonatal complications after the administration of indomethacin for preterm labor. N Engl J Med. 1993;329:1602-1607
16. Groome LJ, Goldenberg RL, Cliver SP, Davis RO, Copper RL, March of Dimes Multicenter Study Group. Neonatal periventricular-intraventricular hemorrhage after maternal ß-sympathomimetic tocolysis. Am J Obstet Gynecol. 1992;167:873-879
17. Thorp JA, Parriott J, Ferrette-Smith D, Meyer BA, Cohen GR, Johnson J Antepartum vitamin K and phenobarbital for preventing intraventricular hemorrhage in the premature newborn: a randomized, double-blind, placebo-controlled study. Obstet Gynecol. 1994;83:70-76
18. Wimberley PD, Lou HC, Pederson H, Heijl M, Lassen NA, Friis-Hansen B. Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn. Acta Paediatr Scand. 1982;71:537-542
19. Goddard-Finegold J, Armstrong DL. Reduction in incidence of periventricular, intraventricular hemorrhages in hypertensive newborn beagles pretreated with phenobarbital. Pediatrics. 1987;79:901-906