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Volumn 39, Issue 4 I, 1996, Pages 697-707

Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: Agonists evoke supersensitivity accompanied by failure of receptor down-regulation

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; ISOPRENALINE;

EID: 0029869468     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199604000-00023     Document Type: Article
Times cited : (20)

References (60)
  • 1
    • 0022706511 scopus 로고
    • The "stress" of being born
    • Lagercrantz H, Slotkin TA 1986 The "stress" of being born. Sci Am 254:100-107
    • (1986) Sci Am , vol.254 , pp. 100-107
    • Lagercrantz, H.1    Slotkin, T.A.2
  • 2
    • 0018578323 scopus 로고
    • Autonomic control of liver glycogen metabolism
    • Lautt WW 1979 Autonomic control of liver glycogen metabolism. Med Hypotheses 5:1287-1296
    • (1979) Med Hypotheses , vol.5 , pp. 1287-1296
    • Lautt, W.W.1
  • 3
    • 0024407563 scopus 로고
    • Glycogenolytic responsiveness to glucagon, epinephrine, vasopressin and angiotensin II in the liver of developing hypothyroid rats. A comparative study of in vitro hormonal binding and in vivo biological response
    • Ali M, Cantau B, Clos J 1989 Glycogenolytic responsiveness to glucagon, epinephrine, vasopressin and angiotensin II in the liver of developing hypothyroid rats. A comparative study of in vitro hormonal binding and in vivo biological response. J Dev Physiol 11:360-367
    • (1989) J Dev Physiol , vol.11 , pp. 360-367
    • Ali, M.1    Cantau, B.2    Clos, J.3
  • 6
    • 0025966996 scopus 로고
    • Glucocorticoids regulate the ontogenetic transition of adrenergic receptor subtypes in rat liver
    • Huff RA, Seidler FJ, Slotkin TA 1991 Glucocorticoids regulate the ontogenetic transition of adrenergic receptor subtypes in rat liver. Life Sci 48:1059-1066
    • (1991) Life Sci , vol.48 , pp. 1059-1066
    • Huff, R.A.1    Seidler, F.J.2    Slotkin, T.A.3
  • 7
    • 0017380638 scopus 로고
    • Catecholamine release in the newborn infant at birth
    • Lagercrantz H, Bistoletti P 1973 Catecholamine release in the newborn infant at birth. Pediatr Res 11:889-893
    • (1973) Pediatr Res , vol.11 , pp. 889-893
    • Lagercrantz, H.1    Bistoletti, P.2
  • 8
    • 0023850755 scopus 로고
    • Adrenomedullary catecholamine release in the fetus and newborn: Secretory mechanisms and their role in stress and survival
    • Slotkin TA, Seidler FJ 1988 Adrenomedullary catecholamine release in the fetus and newborn: secretory mechanisms and their role in stress and survival. J Dev Physiol 10:1-16
    • (1988) J Dev Physiol , vol.10 , pp. 1-16
    • Slotkin, T.A.1    Seidler, F.J.2
  • 9
    • 0002668452 scopus 로고
    • Endocrine control of synaptic development in the sympathetic nervous system: The cardiac-sympathetic axis
    • Gootman PM (ed) Humana Press, Clifton, NJ
    • Slotkin TA 1986 Endocrine control of synaptic development in the sympathetic nervous system: the cardiac-sympathetic axis. In: Gootman PM (ed) Developmental Neurobiology of the Autonomic Nervous System. Humana Press, Clifton, NJ, pp 97-133
    • (1986) Developmental Neurobiology of the Autonomic Nervous System , pp. 97-133
    • Slotkin, T.A.1
  • 12
    • 0019502424 scopus 로고
    • β-Adrenergic receptor subtypes: Properties, distribution, and regulation
    • Minneman KP, Pittman RN, Molinoff PB 1981 β-Adrenergic receptor subtypes: properties, distribution, and regulation. Ann Rev Neurosci 4:419-461
    • (1981) Ann Rev Neurosci , vol.4 , pp. 419-461
    • Minneman, K.P.1    Pittman, R.N.2    Molinoff, P.B.3
  • 14
    • 0024435669 scopus 로고
    • Mechanisms of receptor activation in adenylate cyclase
    • Stiles GL 1989 Mechanisms of receptor activation in adenylate cyclase. J Cardiovasc Pharmacol 14:S1-S5
    • (1989) J Cardiovasc Pharmacol , vol.14
    • Stiles, G.L.1
  • 15
    • 0022499614 scopus 로고
    • Effects of chemical sympathectomy with 6-hydoxydopamine on α- and β-adrenoceptors and muscarinic cholinoceptors in rat kidney
    • Yamada S, Yamamura HI, Roeske WR 1986 Effects of chemical sympathectomy with 6-hydoxydopamine on α- and β-adrenoceptors and muscarinic cholinoceptors in rat kidney. Eur J Pharmacol 121:345-353
    • (1986) Eur J Pharmacol , vol.121 , pp. 345-353
    • Yamada, S.1    Yamamura, H.I.2    Roeske, W.R.3
  • 16
    • 0018422851 scopus 로고
    • Alpha- and beta-adrenergic receptors of the rat salivary gland: Elevation after chemical sympathectomy
    • Pointon SE, Banerjee SP 1979 Alpha- and beta-adrenergic receptors of the rat salivary gland: elevation after chemical sympathectomy. Biochim Biophys Acta 584:231-241
    • (1979) Biochim Biophys Acta , vol.584 , pp. 231-241
    • Pointon, S.E.1    Banerjee, S.P.2
  • 17
    • 0018961875 scopus 로고
    • Alterations in cardiac autonomic receptors following 6-hydroxydopamine
    • Yamada S, Yamamura HI, Roeske WR 1980 Alterations in cardiac autonomic receptors following 6-hydroxydopamine. Mol Pharmacol 18:185-192
    • (1980) Mol Pharmacol , vol.18 , pp. 185-192
    • Yamada, S.1    Yamamura, H.I.2    Roeske, W.R.3
  • 18
    • 0020397719 scopus 로고
    • Maturation of sympathetic neurotransmission in the rat heart. IX. Development of transsynaptic regulation of cardiac adrenergic sensitivity
    • Lau C, Burke SP, Slotkin TA 1982 Maturation of sympathetic neurotransmission in the rat heart. IX. Development of transsynaptic regulation of cardiac adrenergic sensitivity. J Pharmacol Exp Ther 223:675-680
    • (1982) J Pharmacol Exp Ther , vol.223 , pp. 675-680
    • Lau, C.1    Burke, S.P.2    Slotkin, T.A.3
  • 21
    • 0026460414 scopus 로고
    • s in heterologous desensitization: A role for adenosine 3′,5′-monophosphate-dependent phosphorylation
    • s in heterologous desensitization: a role for adenosine 3′,5′-monophosphate-dependent phosphorylation. Endocrinology 131:2774-2784
    • (1992) Endocrinology , vol.131 , pp. 2774-2784
    • Premont, R.T.1    Jacobowitz, O.2    Iyengar, R.3
  • 22
    • 0024367312 scopus 로고
    • Identification of a specific site required for rapid heterologous desensitization of the β-adrenergic receptor by cAMP-dependent protein kinase
    • Clark RB, Friedman J, Dixon RA, Strader CD 1989 Identification of a specific site required for rapid heterologous desensitization of the β-adrenergic receptor by cAMP-dependent protein kinase. Mol Pharmacol 36:343-348
    • (1989) Mol Pharmacol , vol.36 , pp. 343-348
    • Clark, R.B.1    Friedman, J.2    Dixon, R.A.3    Strader, C.D.4
  • 23
    • 0024477069 scopus 로고
    • s-catalytic unit complex of adenylate cyclase in isoproterenol-induced heterologous desensitization
    • s-catalytic unit complex of adenylate cyclase in isoproterenol-induced heterologous desensitization. Eur J Pharmacol 159:247-256
    • (1989) Eur J Pharmacol , vol.159 , pp. 247-256
    • Yamashita, A.1    Kurokawa, T.2    Une, Y.3    Ishibashi, S.4
  • 24
    • 0028985998 scopus 로고
    • Reduced β-adrenergic receptor activation decreases G-protein expression and β-adrenergic receptor kinase activity in porcine heart
    • Ping PP, Gelzer-Bell R, Roth DA, Kiel D, Insel PA, Hammond HK 1995 Reduced β-adrenergic receptor activation decreases G-protein expression and β-adrenergic receptor kinase activity in porcine heart. J Clin Invest 95:1271-1280
    • (1995) J Clin Invest , vol.95 , pp. 1271-1280
    • Ping, P.P.1    Gelzer-Bell, R.2    Roth, D.A.3    Kiel, D.4    Insel, P.A.5    Hammond, H.K.6
  • 25
    • 0019842083 scopus 로고
    • Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein
    • Seamon K, Daly JW 1981 Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein. J Biol Chem 256:9799-9801
    • (1981) J Biol Chem , vol.256 , pp. 9799-9801
    • Seamon, K.1    Daly, J.W.2
  • 27
    • 0025953997 scopus 로고
    • Developmental changes in adenylyl cyclase and GTP binding proteins in brown fat
    • Chaudhry A, Granneman JG 1991 Developmental changes in adenylyl cyclase and GTP binding proteins in brown fat. Am J Physiol 261:R403-R411
    • (1991) Am J Physiol , vol.261
    • Chaudhry, A.1    Granneman, J.G.2
  • 29
    • 0018383484 scopus 로고
    • Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the preweanling rat
    • Seidler FJ, Slotkin TA 1979 Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the preweanling rat. Br J Pharmacol 65:431-434
    • (1979) Br J Pharmacol , vol.65 , pp. 431-434
    • Seidler, F.J.1    Slotkin, T.A.2
  • 30
    • 0022539841 scopus 로고
    • Mechanisms of adrenergic control of blood pressure in developing rats
    • Mills E, Smith PG 1986 Mechanisms of adrenergic control of blood pressure in developing rats. Am J Physiol 250:R188-R192
    • (1986) Am J Physiol , vol.250
    • Mills, E.1    Smith, P.G.2
  • 31
    • 0024439588 scopus 로고
    • Development of the linkage of β-adrenergic receptors to cardiac hypertrophy and heart rate control: Neonatal sympathectomy with 6-hydroxydopamine
    • Hou Q-C, Seidler FJ, Slotkin TA 1989 Development of the linkage of β-adrenergic receptors to cardiac hypertrophy and heart rate control: neonatal sympathectomy with 6-hydroxydopamine. J Dev Physiol 11:305-311
    • (1989) J Dev Physiol , vol.11 , pp. 305-311
    • Hou, Q.-C.1    Seidler, F.J.2    Slotkin, T.A.3
  • 33
    • 0027935689 scopus 로고
    • Postnatal development of ornithine decarboxylase and polyamines in the mouse kidney: Influence of testosterone
    • Sánchez-Capelo A, Peñafiel R, Tovar A, Galindo JD, Cremades A 1994 Postnatal development of ornithine decarboxylase and polyamines in the mouse kidney: influence of testosterone. Biol Neonate 66:119-127
    • (1994) Biol Neonate , vol.66 , pp. 119-127
    • Sánchez-Capelo, A.1    Peñafiel, R.2    Tovar, A.3    Galindo, J.D.4    Cremades, A.5
  • 34
    • 0025252452 scopus 로고
    • Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues
    • Slotkin TA, Navarro HA, McCook EC, Seidler FJ 1990 Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues. Life Sci 47:1561-1567
    • (1990) Life Sci , vol.47 , pp. 1561-1567
    • Slotkin, T.A.1    Navarro, H.A.2    McCook, E.C.3    Seidler, F.J.4
  • 35
    • 0026002590 scopus 로고
    • Control of adenylate cyclase activity in developing rat heart and liver: Effects of prenatal exposure to terbutaline or dexamethasone
    • Navarro HA, Kudlacz EM, Slotkin TA 1991 Control of adenylate cyclase activity in developing rat heart and liver: effects of prenatal exposure to terbutaline or dexamethasone. Biol Neonate 60:127-136
    • (1991) Biol Neonate , vol.60 , pp. 127-136
    • Navarro, H.A.1    Kudlacz, E.M.2    Slotkin, T.A.3
  • 36
    • 0022894999 scopus 로고
    • Effects of neonatal methylmercury exposure on adrenergic receptor binding sites in peripheral tissues of the developing rat
    • Slotkin TA, Kavlock RJ, Cowdery T, Orband L, Bartolome M, Whitmore WL, Bartolome J 1986 Effects of neonatal methylmercury exposure on adrenergic receptor binding sites in peripheral tissues of the developing rat. Toxicology 41:95-106
    • (1986) Toxicology , vol.41 , pp. 95-106
    • Slotkin, T.A.1    Kavlock, R.J.2    Cowdery, T.3    Orband, L.4    Bartolome, M.5    Whitmore, W.L.6    Bartolome, J.7
  • 38
    • 0028980802 scopus 로고
    • β-Adrenoceptor control of cardiac adenylyl cyclase during development: Agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization
    • Giannuzzi CE, Seidler FJ, Slotkin TA 1995 β-Adrenoceptor control of cardiac adenylyl cyclase during development: agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization. Brain Res 694:271-278
    • (1995) Brain Res , vol.694 , pp. 271-278
    • Giannuzzi, C.E.1    Seidler, F.J.2    Slotkin, T.A.3
  • 40
    • 0024948654 scopus 로고
    • Ontogeny of fetal adenylate cyclase; mechanisms for regulation of β-adrenergic receptors
    • Maier JA, Roberts JM, Jacobs MM 1989 Ontogeny of fetal adenylate cyclase; mechanisms for regulation of β-adrenergic receptors. J Dev Physiol 12:249-261
    • (1989) J Dev Physiol , vol.12 , pp. 249-261
    • Maier, J.A.1    Roberts, J.M.2    Jacobs, M.M.3
  • 41
    • 0029134523 scopus 로고
    • Neural input and the development of adrenergic intracellular signaling: Neonatal denervation evokes neither receptor up-regulation nor persistent supersensitivity of adenylate cyclase
    • Slotkin TA, Lorber BA, McCook EC, Barnes GA, Seidler FJ 1995 Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor up-regulation nor persistent supersensitivity of adenylate cyclase. Dev Brain Res 88:17-29
    • (1995) Dev Brain Res , vol.88 , pp. 17-29
    • Slotkin, T.A.1    Lorber, B.A.2    McCook, E.C.3    Barnes, G.A.4    Seidler, F.J.5
  • 42
    • 0019361693 scopus 로고
    • Development of central control of norepinephrine turnover and release in the rat heart: Responses to tyramine, 2-deoxyglucose and hydralazine
    • Seidler FJ, Slotkin TA 1981 Development of central control of norepinephrine turnover and release in the rat heart: responses to tyramine, 2-deoxyglucose and hydralazine. Neuroscience 6:2081-2086
    • (1981) Neuroscience , vol.6 , pp. 2081-2086
    • Seidler, F.J.1    Slotkin, T.A.2
  • 43
    • 0020071210 scopus 로고
    • Development of sympathetic ganglionic neurotransmission in the neonatal rat. Pre- and postganglionic nerve response to asphyxia and 2-deoxyglucose
    • Smith PG, Slotkin TA, Mills E 1982 Development of sympathetic ganglionic neurotransmission in the neonatal rat. Pre- and postganglionic nerve response to asphyxia and 2-deoxyglucose. Neuroscience 7:501-507
    • (1982) Neuroscience , vol.7 , pp. 501-507
    • Smith, P.G.1    Slotkin, T.A.2    Mills, E.3
  • 45
    • 0028085730 scopus 로고
    • 1-adrenoceptors and adenylyl cyclase activity in neonatal rat ventricular myocytes
    • 1-adrenoceptors and adenylyl cyclase activity in neonatal rat ventricular myocytes. Naunyn-Schmiedebergs Arch Pharmacol 350:267-276
    • (1994) Naunyn-Schmiedebergs Arch Pharmacol , vol.350 , pp. 267-276
    • Paraschos, A.1    Karliner, J.S.2
  • 46
    • 0024372926 scopus 로고
    • Phosphatidic acid phosphatase in neonatal rat lung: Effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to β-adrenergic stimulation
    • Kudlacz EM, Navarro HA, Slotkin TA 1989 Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to β-adrenergic stimulation. J Pharmacol Exp Ther 250:236-240
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 236-240
    • Kudlacz, E.M.1    Navarro, H.A.2    Slotkin, T.A.3
  • 47
    • 0020695436 scopus 로고
    • Prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems
    • Friedhoff AJ, Miller JC 1983 Prenatal psychotropic drug exposure and the development of central dopaminergic and cholinergic neurotransmitter systems. Monogr Neural Sci 9:91-98
    • (1983) Monogr Neural Sci , vol.9 , pp. 91-98
    • Friedhoff, A.J.1    Miller, J.C.2
  • 48
    • 0026357342 scopus 로고
    • Role of serotonin and other neurotransmitter receptors in brain development: Basis for developmental pharmacology
    • Whitaker-Azmitia PM 1991 Role of serotonin and other neurotransmitter receptors in brain development: basis for developmental pharmacology. Pharmacol Rev 43:553-561
    • (1991) Pharmacol Rev , vol.43 , pp. 553-561
    • Whitaker-Azmitia, P.M.1
  • 49
    • 0024462465 scopus 로고
    • Role of sympathetic neurons in development of β-adrenergic control of ornithine decarboxylase activity in peripheral tissues: Effects of neonatal 6-hydroxydopamine treatment
    • Hou Q-C, Baker FE, Seidler FJ, Bartolome M, Bartolome J, Slotkin TA 1989 Role of sympathetic neurons in development of β-adrenergic control of ornithine decarboxylase activity in peripheral tissues: effects of neonatal 6-hydroxydopamine treatment. J Dev Physiol 11:139-146
    • (1989) J Dev Physiol , vol.11 , pp. 139-146
    • Hou, Q.-C.1    Baker, F.E.2    Seidler, F.J.3    Bartolome, M.4    Bartolome, J.5    Slotkin, T.A.6
  • 50
    • 0024918037 scopus 로고
    • Neonatal sympathectomy compromises development of responses of ornithine decarboxylase to hormonal stimulation in peripheral tissues
    • Hou Q-C, Eylers JP, Lappi SE, Kavlock RJ, Slotkin TA 1989 Neonatal sympathectomy compromises development of responses of ornithine decarboxylase to hormonal stimulation in peripheral tissues. J Dev Physiol 12:189-192
    • (1989) J Dev Physiol , vol.12 , pp. 189-192
    • Hou, Q.-C.1    Eylers, J.P.2    Lappi, S.E.3    Kavlock, R.J.4    Slotkin, T.A.5
  • 51
    • 0025778668 scopus 로고
    • Presynaptic input regulates development of β-adrenergic control of rat brain ornithine decarboxylase: Effects of 6-hydroxydopamine or propranolol
    • Wagner JP, Seidler FJ, Slotkin TA 1991 Presynaptic input regulates development of β-adrenergic control of rat brain ornithine decarboxylase: effects of 6-hydroxydopamine or propranolol. Brain Res Bull 26:885-890
    • (1991) Brain Res Bull , vol.26 , pp. 885-890
    • Wagner, J.P.1    Seidler, F.J.2    Slotkin, T.A.3
  • 52
    • 0028903451 scopus 로고
    • Role of presynaptic input in the ontogeny of adrenergic cell signaling in rat brain: β receptors, adenylate cyclase, and c-fos protooncogene expression
    • Wagner JP, Seidler FJ, Lappi SE, McCook EC, Slotkin TA 1995 Role of presynaptic input in the ontogeny of adrenergic cell signaling in rat brain: β receptors, adenylate cyclase, and c-fos protooncogene expression. J Pharmacol Exp Ther 273:415-426
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 415-426
    • Wagner, J.P.1    Seidler, F.J.2    Lappi, S.E.3    McCook, E.C.4    Slotkin, T.A.5
  • 53
    • 0027057008 scopus 로고
    • Promotional role for glucocorticoids in the development of intracellular signalling: Enhanced cardiac and renal adenylate cyclase reactivity to β-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure
    • Bian X-P, Seidler FJ, Slotkin TA 1992 Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to β-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. J Dev Physiol 17:289-297
    • (1992) J Dev Physiol , vol.17 , pp. 289-297
    • Bian, X.-P.1    Seidler, F.J.2    Slotkin, T.A.3
  • 54
    • 0027505681 scopus 로고
    • Glucocorticoid regulation of G-protein subunits in neonatal liver
    • Kawai Y, Arinze IJ 1993 Glucocorticoid regulation of G-protein subunits in neonatal liver. Mol Cell Endocrinol 90:203-209
    • (1993) Mol Cell Endocrinol , vol.90 , pp. 203-209
    • Kawai, Y.1    Arinze, I.J.2
  • 55
    • 0027180085 scopus 로고
    • Glucocorticoids regulate the development of intracellular signaling: Enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure
    • Slotkin TA, McCook EC, Seidler FJ 1993 Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure. Brain Res Bull 32:359-364
    • (1993) Brain Res Bull , vol.32 , pp. 359-364
    • Slotkin, T.A.1    McCook, E.C.2    Seidler, F.J.3
  • 56
    • 0027981426 scopus 로고
    • Glucocorticoids enhance intracellular signaling via adenylate cyclase at three distinct loci in the fetus: A mechanism for heterologous teratogenic sensitization?
    • Slotkin TA, Lau C, McCook EC, Lappi SE, Seidler FJ 1994 Glucocorticoids enhance intracellular signaling via adenylate cyclase at three distinct loci in the fetus: a mechanism for heterologous teratogenic sensitization? Toxicol Appl Pharmacol 127:64-75
    • (1994) Toxicol Appl Pharmacol , vol.127 , pp. 64-75
    • Slotkin, T.A.1    Lau, C.2    McCook, E.C.3    Lappi, S.E.4    Seidler, F.J.5
  • 58
    • 0026378086 scopus 로고
    • Thyroid hormone differentially regulates development of β-adrenergic receptors, adenylate cyclase and ornithine decarboxylase in rat heart and kidney
    • Pracyk JB, Slotkin TA 1991 Thyroid hormone differentially regulates development of β-adrenergic receptors, adenylate cyclase and ornithine decarboxylase in rat heart and kidney. J Dev Physiol 16:251-261
    • (1991) J Dev Physiol , vol.16 , pp. 251-261
    • Pracyk, J.B.1    Slotkin, T.A.2
  • 59
    • 0026577962 scopus 로고
    • Effects of thyroid hormone on myocardial adrenergic β-receptor responsiveness and function during late gestation
    • Birk E, Tyndall MR, Erickson LC, Rudolph AM, Roberts JM 1992 Effects of thyroid hormone on myocardial adrenergic β-receptor responsiveness and function during late gestation. Pediatr Res 31:468-473
    • (1992) Pediatr Res , vol.31 , pp. 468-473
    • Birk, E.1    Tyndall, M.R.2    Erickson, L.C.3    Rudolph, A.M.4    Roberts, J.M.5
  • 60
    • 0027959794 scopus 로고
    • Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: β receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression
    • Wagner JP, Seidler FJ, Lappi SE, McCook EC, Slotkin TA 1994 Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: β receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression. J Pharmacol Exp Ther 271:472-483
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 472-483
    • Wagner, J.P.1    Seidler, F.J.2    Lappi, S.E.3    McCook, E.C.4    Slotkin, T.A.5


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