Effect of neurotrophic factors on the inner ear: Clinical implications

Acta Oto-Laryngologica

Volumn 116, Issue 2, 1996, Pages 248-252

  Kopke, Richard ^a   Staecker, Hinrich ^a,b   Lefebvre, Philippe ^b   Malgrange, Bridgitte ^b   Moonen, Gustave ^b   Ruben, Robert J ^a   Van De Water, Thomas R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Auditory neurons; Brain derived neurotrophic factor (BDNF); Neuritogenesis; Neuronal survival; Neurotrophin 3 (NT 3); Sensorineural deafness

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3;

ACOUSTIC NERVE FIBER; ARTICLE; HUMAN; NERVOUS SYSTEM DEVELOPMENT; PERCEPTION DEAFNESS; PRIORITY JOURNAL;

EID: 0029869398     PISSN: 00016489     EISSN: None     Source Type: Journal    
DOI: 10.3109/00016489609137834     Document Type: Article

References (25)

1. Ard M, Morest D, Haugher S. Trophic interactions between the cochleovestibular ganglion of the chick embryo and its synaptic targets in culture. Neuroscience 1985; 16: 151-70.
2. Zhou Y, Van De Water TR. The effect of target tissues on survival and differentiation of mammalian statoacoustic ganglion neurons in organ culture. Acta Otolaryngol (Stockh) 1987; 104: 90-8.
3. Lefebvre PP, Van De Water TR, Weber T. Growth factor interactions in cultures of dissociated adult acoustic ganglia: neuronotrophic effects. Brain Res 1991; 567: 306-12.
4. Lefebvre PP, Staecker H, Weber T, Van De Water TR, Rogister B, Moonen G. TGFβ, modulates bFGF receptor message expression in cultured adult auditory neurons. NeuroReport 1991; 2: 305-8.
5. Lefebvre PP, Weber T, Rigo JM, Staecker H, Moonen G, Van De Water TR. Peripheral and central targetderived trophic factor(s) effects on auditory neurons. Hear Res 1992; 58: 185-92.
6. Lefebvre PP, Malgrange B, Staecker H, Moghadassi M, Van De Water TR, Moonen G. Neur otrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro. NeuroReport 1994; 5: 865-8.
7. Staecker H, Liu W, Hartnick C et al. NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants. NeuroReport 1995; 6: 1533-7.
8. Ernfors P, Van De Water TR, Loring J, Jaenisch R. Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 1995; 14: 1153-64.
9. Spoendlin H. Biology of the cochleo-vestibular nerve. In: Alberti PW, Ruben RJ, eds. Otologic medicine and surgery. New York: Churchill Livingston, 1988: 117-50.
10. Ylikoski J, Pirvola U, Moshynakov M, Palgi J, Arumae U, Saarma M. Expression patterns of neurotrophins and their receptor mRNA in the rat inner ear. Hear Res 1993; 56: 69-78.
11. Luo L, Moore J, Baird A, Ryan A. Acidic and basic FGF mRNA expression in the adult and developing rat cochlea. Hear Res 1993; 69: 182-93.
12. Wilkinson DG, Bhatt S, McMahon AE. Expression pattern of the FGF related proto-oncogene int-2 suggests multiple roles in fetal development. Development 1989; 105: 131-6.
13. Lefebvre PP, Martin D, Staecker H, Weber T, Moonen G, Van De Wter TR. TGFβ, expression is initiated in adult auditory neurons by sectioning of the auditory nerve. NeuroReport 1992; 3: 295-8.
14. Staecker H, Galinovic-Schwartz V, Liu W et al. The role of the neurotrophins in maturation and maintenance of postnatal auditory innervation. Am J Otol 1996 (in press).
15. Zhang JL, Stewart RR, Gao W. Neurotrophin 4/5 enhances survival of cultured spiral ganglion neurons and protects them from cisplatin neurotoxicity. J Neurosci 1995; 15: 5079-87.
16. Juhn SK, Rybak LP, Prado S. Nature of blood-labyrinth barrier in experimental conditions. Ann Otol Rhinol Laryngol 1981; 90: 135-41.
17. Monsell EM, Cass SP, Rybak LP. Therapeutic use of aminoglycosides in Meniere's disease. Otolaryngol Clin North Am 1993; 26: 737-46.
18. Brown JN, Miller JM, Atlschuler RA, Nutall AL. Osmotic pump implant for chronic infusion of drugs into the inner ear. Hear Res 1993; 70: 167-72.
19. McElveen JT Jr, Wilkins RH, Molter DW, Erwin AC, Wolford RD. Hearing preservation using the modified translabyrinthine approach. Otolaryngol Head and Neck Surg 1993; 108: 671-9.
20. Hirsch BE, Cass SP, Sekhar LN, Wright DC. Translabyrinthine approach to skull base tumors with hearing perservation. Am J Otol 1993; 14: 533-43.
21. Fishman JB, Rubin JB, Handrahan JV, Connor JR, Fine RE. Receptor-mediated transcytosis of transferrin across the blood-brain barrier. J Neurosci Res 1987; 18: 299-304.
22. Staecker H, Kopke R, Lefebvre PP et al. The effects of neurotrophins on adult auditory neurons in vitro and in vivo. Midwinter Meeting of Asso Res Otolaryng February 1995; Abst # 705, St. Petersburg FLA.
23. Van De Water TR, Staecker H, Apfel S, Lefebvre PP. Regeneration of the auditory nerve: the role of neurotrophic factors. In: Van De Water TR, Fay R, Popper A, eds. Clinical aspects of hearing, New York: Springer-Verlag 1995.
24. Nadol J, Young Y, Glynn, R. Survival of spiral ganglion neurons in profound sensorineural hearing loss: Implications for cochlear implantation. Ann Otol Rhinol Laryngol 1989; 98:411-6.
25. Marsh MA, Cohen NJ, Jenkins HA. Temporal bone histopathology of a patient with a nucleus 22 channel cochlear implant. Presented at the 26th Annual Scientific Meeting of the American Neurotology Soc 1991, Waikoloa, Hawaii.