Inositolphosphoglycans are possible mediators of the glucagon-like peptide 1 (7-36)amide action in the liver

Journal of Endocrinological Investigation

Volumn 19, Issue 2, 1996, Pages 114-118

  Trapote, M A ^a   Clemente, F ^a   Galera, C ^a   Morales, M ^a   Alcantara A I ^a   Lopez Delgado M I ^a   Villanueva Penacarrillo, M L ^a,b   Valverde, I ^a  

^a Hospital UniversitarioFundación Jiménez Díaz   (Spain)

^b Dpto Metabolismo Nutr y Hormonas   (Spain)

Author keywords

GLP 1(7 36)amide; Glycogen synthase; Glycogenesis; Glycosilphosphatidilinositols (GPIs); HEP G 2 cells; Inositolphosphoglycans (IPGs)

Indexed keywords

GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; GLYCOGEN; GLYCOSYLPHOSPHATIDYLINOSITOL; INSULIN;

ARTICLE; CONTROLLED STUDY; GLYCOGEN SYNTHESIS; HEPATOMA CELL; HUMAN; HUMAN CELL; HYDROLYSIS; ISOTOPE LABELING; LIVER CELL; LIVER METABOLISM; SECOND MESSENGER;

EID: 0029869017     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03349846     Document Type: Article

References (28)

1. Valverde I., Morales M., Clemente F., López-Delgado M.I., Delgado E., Perea A., Villanueva-Peñacarrillo M.L Glucagon-like peptide 1: a potent glycogenic hormone. FEBS Lett. 349: 313, 1994.
2. Villanueva-Peñacarrillo M.L., Alcántara A., Clemente F., Delgado E., Valverde I. Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle. Diabetologia 37: 1163, 1994.
3. Villanueva-Pen̄acarrillo M.L., Delgado E., Trapote M.A., Alcántara A., Clemente F., Luque M.A., Perea A., Valverde I. Glucagon-like peptide-1 binding to rat hepatic membranes. J. Endocrinol. 146: 183, 1995.
4. Delgado E., Luque M.A., Alcántara A., Trapote M.A., Clemente F., Galera C., Valverde I., Villanueva-Peñacarrillo M.L. Glucagon-like peptide-1 binding to rat skeletal muscle. Peptides 16: 225, 1995.
5. Thorens B. Expression cloning of the pancreatic ßcell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc. Natl. Acad. Sci. USA 89: 8641, 1992.
6. Drucker D.J., Philippe J., Mojsov S., Chick W.L., Habener J.F. Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proc. Natl. Acad. Sci. USA 84: 3434, 1987.
7. Irvine F., Wallace A.V., Sarawak S.R., Houslay M.D. Extracellular calcium modulates insulin's action on enzymes controlling cyclic AMP metabolism in intact hepatocytes. Biochem. J. 293: 249, 1993.
8. Rosen O.M. After insulin binds. Science 237: 1452, 1987.
9. Saltiel A.R., Cuatrecasas P. Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid. Proc. Natl. Acad. Sci. USA 83: 5793, 1986.
10. Saltiel A.R., Fox J.A., Sherline P., Cuatrecasas P. Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. Science 233: 967, 1986.
11. Lamer J., Galasko G., Cheng K., DePaoli-Roach A.A., Huang L., Daggy P., Kellogg J. Generation by insulin of a chemical mediator that controls protein phosphorylation and dephosphorylation. Science 206: 1408, 1979.
12. Jarett L., Seals J.R. Pyruvate dehydrogenase activation in adipocyte mitochondria by an insulin-generated mediator from muscle. Science 206: 1407, 1979.
13. Suzuki S., Toyota T., Suzuki H., Goto Y. A putative second messenger of insulin action regulates hepatic microsomal glucose-6-phosphatase. Biochem. Biophys. Res. Commun. 118: 40, 1984.
14. Suzuki S., Toyota T., Suzuki H., Goto Y. Partial purification from human mononuclear cells and placental plasma membranes of an insulin mediator which stimulates pyruvate dehydrogenase and suppresses glucose-6-phosphatase. Arch. Biochem. Biophys. 235: 418, 1984.
15. Larner J. Insulin-signaling mechanisms. Lessons from the old testament of glycogen metabolism and the new testament of molecular biology. Diabetes 37: 262, 1988.
16. Mato J.M., Kelly K.L., Abler A., Jarett L. Identification of a novel insulin-sensitive glycophospholipid from H35 hepatoma cells. J. Biol. Chem. 262: 2131, 1987.
17. Sánchez-Arias J.A., Sánchez-Gutiérrez J.C., Guadaño A., Alvarez J.F., Samper B., Mato J.M., Feliu J.E. Impairment of glycosyl-phosphatidylinositol-dependen insulin signaling system in isolated rat hepatocytes by streptozotocin-induced diabetes. Endocrinology 131: 1727, 1992.
18. Farese R.V., Cooper D.R., Konda T.S., Nair G., Standaert M.L., Rollet R.J. Insulin provokes coordinated increases in the synthesis of phosphatidylinositol, phosphatidylinositol phosphates and the phosphatidylinositolglycan in BC3H-1 myocytes. Biochem. J. 256: 185, 1988.
19. Romero G., Luttrell L., Rogol A., Zeller K., Hewlett E., Larner J. Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators. Science 240: 509, 1988.
20. Mato J.M., Kelly K.L., Abler A., Jarett L., Corkey B.E., Cashel U.A., Zopf D. Partial structure of an insulin-sensitive glycophospholipid. Biochem. Biophys. Res. Commun. 146: 764, 1987.
21. Larner J., Huang L.C., Schwartz C.F., Oswald A.S., Shen T.Y., Kinter M., Tang G.Z., Zeller K. Rat liver insulin mediator which stimulates pyruvate dehydrogenase phosphate contains galactosamine and D-chiroinositol. J. Biochem. Biophys. Res. Commun. 151: 1416, 1988.
22. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248, 1976.
23. Fleig W.E., Noether-Fleig G., Fussgaenger R., Ditschuneit H. Modulation by a sulfonylurea of insulin-dependent glycogenesis, but not of insulin binding, in cultured rat hepatocytes. Diabetes 33: 285, 1984.
24. Hue L., Bontemps F., Hers H.G. The effect of glucose and of potassium ions on the interconversion of the two forms of glycogen phosphorylase and of glycogen synthetase in isolated rat liver preparation. Biochem. J. 152: 105, 1975.
25. Albor A., Camara J., Mato J.M., Malaisse W.J., Valverde I. Metabolic labelling and partial characterization of glycolipids in pancreatic islet cells. Cell. Biochem. Funct. 9: 71, 1991.
26. Kreymann B., Ghatei M.A., Williams G., Bloom S.R. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 2: 1300, 1987.
27. Orskov C., Jeppesen J., Madsbad S., Holst J.J. Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine. J. Clin. Invest. 87: 415, 1991.
28. Fukase N., Igarashi M., Takahashi H., Manaka H., Yamatani K., Daimon M., Tominaga M., Sasaki H. Hypersecretion of truncated glucagon-like peptide1 and gastric inhibitory polypeptide in obese patients. Diabet. Med. 10: 44, 1993.