Effects of ipriflavone and its metabolites on human articular chondrocytes cultivated in clusters

Osteoarthritis and Cartilage

Volumn 4, Issue 1, 1996, Pages 1-8

  Bassleer, C T ^a   Franchimont, P P ^a   Henrotin, Y E ^a   Franchimont, N M ^a   Greenen, V G ^a   Reginster, J Y L ^a  

^a Centre Universitaire Exploration   (Belgium)

Author keywords

Cartilage; Collagen; Ipriflavone; Proteoglycans

Indexed keywords

DRUG METABOLITE; IPRIFLAVONE;

ARTICLE; CARTILAGE CELL; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0029868940     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1063-4584(96)80002-1     Document Type: Article

References (44)

1. Agnusdei D Adami S Cervetti R Effects of ipriflavone on bone mass and calcium metabolism in postmenopausal osteoporosis Bone Min 19 1992 S43 S48
2. Passeri M Biondi M Costi D Effect of ipriflavone on bone mass in elderly osteoporotic women Bone Min 19 1992 S57 S62
3. Agnusdei D Camporebale A Zacchei F Effects of ipriflavone on bone mass and bone remodeling in patients with established postmenopausal osteoporosis Curr Ther Res 51 1992 82 91
4. Reginster JY Ipriflavone: pharmacological properties and usefulness in postmenopausal osteoporosis Bone Min 23 1993 223 232
5. Benvenuti S Tanini A Frediani U Effects of ipriflavone and its metabolites on a clonal osteoblastic cell line J Bone Min Res 6 1991 987 995
6. Notoya K Tsukuda R Yoshida K Taketomi S Stimulatory effect of Ipriflavone on formation of bone-like tissue in rat bone marrow stromal cell culture Calcif Tissue Int 51 S1 1992 S16 S20
7. Chambers TJ McSheepy PM Thomson BM Fuller K The effect of calcium regulating hormones and prostaglandins on bone resorption by osteoclasts disggregated from neonatal rabbit bones Endocrinology 116 1985 234 239
8. Farley JR Hall SL Tarbaux NM Calcitonin (but not calcitonin gene-related peptide) increases mouse bone cell, proliferation in a dose-dependent manner, and increases mouse bone formation, alone or in combination with fluoride Calcif Tissue Int 45 1989 214 221
9. Farley JR Wergedal JE Hall SL Herring S Tarbaux NM Calcitonin has direct effect on [3H]thymidine incorporation and alkaline phosphatase activity in human osteoblast-line cells Calcif Tissue Int 12 1991 297 301
10. Franchimont P Bassleer C Henrotin Y Gysen P Bassleer R Effects of human and salmon calcitonin on human articular chondrocytes cultivated in clusters J Clin Endocrinol Metab 69 1989 259 266
11. Shino M Pharmacokinetic study of ipriflavone (TC80) by oral administration in healthy male volunteers Jap Pharmacol Ther 13 1985 7223 7233
12. Bassleer C Gysen P Foidart JM Bassleer R Franchimont P Human chondrocytes in tridimensional culture In vitro Cell Dev Biol 22 1986 113 119
13. Gysen P Franchimont P Radioimmunoassay of proteoglycans J Immunoassay 5 1984 221 243
14. Roughley PJ McNicol D Santer V Buckwalter J The presence of a cartilage-like proteoglycan in the adult human meniscus Biochem J 197 1981 77 83
15. Bayliss MT Venn M Chemistry of human articular cartilage Maroudas A Holborrow EJ Studies in Joint Disease 1st ed. 1980 Pitman Medical London 2 58
16. Vaitukaitis J Robbins JB Nisechlag E Ross GT A method for producing specific antisera with small doses of immunogen J. Clin Endocrinol Metab 33 1971 988 991
17. 131I-labeled human growth hormone of high specific radioactivity Biochem J 89 1963 114 124
18. Franchimont P Bouffioux Ch Reuter A Radioimmunoassay of prostatic acid phosphatase: validation and clinical application Int J Cancer 31 1983 149 155
19. Henrotin Y Bassleer C Collette J Nusgens B Franchimont P Radioimmunoassay for human type II collagen J Immunoassay 11 1990 555 578
20. Herbage D Bouillet J Bernengo JC Biochemical and physicochemical characterization of pepsinsolubilized type II collagen from bovine articular cartilage Biochem J 161 1977 303 312
21. Salacinsky P Hope J McLean C A new simple method which allows theoritical incorporation of radio-iodine into proteins and peptides without damage J Endocrino 81 1979 131
22. Srinivas GR Barrach HJ Chichester CO Quantitative immunoassays for type II collagen and its cyanogen bromide peptides J Immunol Methods 159 1993 53 62
23. Labarca C Paigen KA A simple, rapid and sensitive DNA assay procedure Anal Biochem 102 1980 344 352
24. Weiss A Livne E Vonder Mark K Heinegard D Silbermann M Growth and repair of cartilage: organ culture system utilizing chondroprogenitor cells of condylar cartilage in newborn mice J Bone Min Res 3 1988 93 100
25. Havsteen B Flavonoids, a class of natural products of high pharmacological potency Biochem Pharmacol 32 1983 1141 1148
26. Moroney MA Alcaraz MJ Forder RA Carey F Hoult JRS Selectivity of neutrophil 5-lipoxygenase and cyclo-oxygenase inhibition by anti-inflammatory flavonoid glycoside and related aglycone flavonoids J. Pharm Pharmacol 40 1988 782 792
27. Alcaraz MJ Ferrandiz ML modification of arachidonic acid metabolism by flavonoids Ethnopharmacology 21 1987 209 229
28. Beretz A Anton R Stoclet JC Flavonoid compounds are potent inhibitors of cyclic AMP phosphodiesterase Experientia 34 1978 1054 1055
29. Kuppusamy UR Khoo HE Das NP Structure activity studies of flavonoids as inhibitors of hyaluronidase Biochem Pharmacol 40 1990 397 401
30. Ogawara H Akiyama T Watanabe S Ilto N Kobori M Seoda Y Inhibition of protein tyrosine kinase activity by synthetic isoflavones and flavones J Antibiot 42 1989 340 343
31. Yamashita Y Kawada SZ Nakano H Induction of mammalian topoisomerase II dependent DNA cleavage by non intercalative flavonoids, genistein and orobol Biochem Pharmacol 39 1990 737 744
32. Inouye Y Yamaguchi K Take Y Nakamura S Inhibition of avian myeloblastosis virus reverse transcriptase by flavones and isoflavones J Antibiot 42 1989 1523 1525
33. Bracka M Vyncke B Opdenakker G Foidart JM de Pestel G Mareel M Effects of catechins and citrus flavonoids on invasion in vitro Clin Exp Metastasis 9 1991 13 25
34. Martin PM Horowitz KB Ryan DS MacGuire WL Phytoestrogen interaction with estrogen receptors in human breast cancer cells Endocrinology 103 1978 1860 1867
35. Setchell KDR Borriello SP Hullme P Kirk DN Axelson M Non steroidal estrogens of dietary origin: possible role in hormone-dependent disease Am J Clin Nutr 40 1984 569 578
36. El Gammal EE Mansour RM Antimicrobial activities of bone flavonoid compounds Zentralbl Mikrobiol 141 1986 561 565
37. Della Loggia R Zilli C Del Negro P Redaelli C Tubaro A Eight isoflavones as spasmolytic principles of Piscidia erythrina Prog Clin Biol Res 280 1988 365 368
38. Jha HC Von Recklinghausen G Zilliken F Inhibition of in vitro microsomal lipid peroxidation by isoflavonoids Biochem Pharmacol 34 1985 1367 1369
39. Fourtillian JB Acerbi D Pharmacokinetics and metabolism of ipriflavone in human Christiansen C Overgaard K Osteoporosis 1990 1990 Osteopress ApS Copenhagen 2151 2155
40. Franchimont P Bassleer C Henrotin Y Reginster JY Ipriflavone inhibits interleukin-1 stimulated neutral metalloprotease synthesis in human chondrocytes Osteoarthritis Cart 2 Suppl 1 1994 50
41. Sziklai I Ribari O The effect of flavone treatment on human otosclerotic ossicle organ cultures Arch Othorinolaryngol 242 1985 67 70
42. 2-induced alterations in percentage collagen synthesis in ossicle organ cultures Acta Otolaryngol (Stockh) 103 1987 657 660
43. Saito AM Pharmacokinetic study of ipriflavone (TC-80) by oral administration in healthy male volunteers Jap Pharm Ther J 13 1985 7223 7233
44. Sato T Koite T Hamda A Ohashi M Shimazu A Pharmacokinetics of ipriflavone tablets in long-term administration to patients with osteoporosis Jap Phar Ther J 14 1986 873 883