Influence of milk on absorption of NM441, a prodrug type of quinolone antibiotic

Japanese Journal of Chemotherapy

Volumn 44, Issue SUPPL. 1, 1996, Pages 221-228

  Saito, Akira ^a   Tarao, Fumiaki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

NM394; NM441; ofloxacin

Indexed keywords

PRULIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ARTICLE; BACTERIAL INFECTION; CLINICAL TRIAL; DRUG ABSORPTION; DRUG EFFECT; DRUG EXCRETION; HUMAN; MALE; NORMAL HUMAN; URINARY EXCRETION;

EID: 0029868921     PISSN: 13407007     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Morino A, Okuyama Y, Momota K, Ohyabu M, Ushimaru K : Pharmacokinetics of NM441, a new quinolone, in laboratory animals. 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy. Anaheim, October, 1992
2. Ozaki M, et al : In vitro antibacterial activity of a new quinolone, NM394. Antimicrob Agents Chemother 35: 2490-2495, 1991
3. Ozaki M, et al : In vivo evaluation of NM441, a new thiazeto-quinoline derivative. Antimicrob Agents Chemother 35 : 2496-2499, 1991
4. Nakashima M, Uematsu T, Kosuge K, Okuyama Y, Morino A, Ozaki M, Takebe Y : Pharmacokinetics and safety of NM 441, a new quinolone, in healthy male volunteers. J Clin Pharmacol 34: 930-937, 1994
5. Pertti J Neuvonen, Kari T Kivistö : Milk and yoghurt do not impair the absorption of ofloxacin. Br J Clin Pharmacol 33 : 346-348, 1992
6. Shiba K, Saito A, Sakai O : Effects of antacids and cimetidine on the absorption and excretion of NM441. 34th Interscience Conference on Antimicrobial Agents and Chemotherapy. Orlando, October, 1994
7. Saito A, Tomizawa M : Blood levels and urinary excretion of DL-8280 in human. 13th International Congress of Chemotherapy. Vienna, August 28 to September 2, 1983
8. Minami R, Inotsume N, Nakano M, Sudo Y, Higashi A, Matsuda I : Effect of milk on absorption of norfloxacin in healthy volunteers. J Clin Pharmacol 33: 1238-1240, 1993
9. Pertti J Neuvonen, Kari T Kivistö, Pasi Lehto : Interference of dairy products with the absorption of ciprofloxacin. Clin Pharmacol Ther 50: 498-502, 1991