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Volumn 13, Issue 1, 1996, Pages 179-182

Triazolines 34. Structure and Stability Relationships of Novel Δ2-1,2,3-Triazoline Anticonvulsants

Author keywords

Chemical stability; Degradation kinetics; Novel triazoline anticonvulsants; Structure stability relationships

Indexed keywords

ANTICONVULSIVE AGENT; TRIAZOLINE DERIVATIVE;

EID: 0029867718     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016018409546     Document Type: Article
Times cited : (3)

References (11)
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  • 2
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    • Triazolines 14. 1,2,3-Triazolines and triazoles, a new class of anticonvulsants. Drug design and structure activity relationships
    • Kadaba, P. K. Triazolines 14. 1,2,3-Triazolines and triazoles, a new class of anticonvulsants. Drug design and structure activity relationships. J. Med. Chem. 31:196-203 (1988).
    • (1988) J. Med. Chem. , vol.31 , pp. 196-203
    • Kadaba, P.K.1
  • 3
    • 0023907873 scopus 로고
    • Triazolines 15. Anticonvulsant profile of ADD17014, a potentially unique 1,2,3-triazoline antiepileptic drug in mice and rats
    • Kadaba, P. K. and Slevin, J. T. Triazolines 15. Anticonvulsant profile of ADD17014, a potentially unique 1,2,3-triazoline antiepileptic drug in mice and rats. Epilepsia. 29:330-337 (1988).
    • (1988) Epilepsia , vol.29 , pp. 330-337
    • Kadaba, P.K.1    Slevin, J.T.2
  • 4
    • 0025221703 scopus 로고
    • 1,2,3-Triazolines: A new generation of anticonvulsant agents effective in the kindling model of epilepsy, with a unique mechanism for impairing excitatory amino acid neurotransmission
    • Kadaba, P. K. 1,2,3-Triazolines: a new generation of anticonvulsant agents effective in the kindling model of epilepsy, with a unique mechanism for impairing excitatory amino acid neurotransmission. Drugs of the Future. 15:1013-1024 (1990).
    • (1990) Drugs of the Future , vol.15 , pp. 1013-1024
    • Kadaba, P.K.1
  • 5
    • 0026725457 scopus 로고
    • Triazolines. XXI. Preformulation degradation kinetics and chemical stability of a novel triazoline anticonvulsant
    • Hamelijnck, M. A. F., Stevenson, P. J., Kadaba, P. K. and Damani, L. A. Triazolines. XXI. Preformulation degradation kinetics and chemical stability of a novel triazoline anticonvulsant. J. Pharm. Sci. 81:392-396 (1992).
    • (1992) J. Pharm. Sci. , vol.81 , pp. 392-396
    • Hamelijnck, M.A.F.1    Stevenson, P.J.2    Kadaba, P.K.3    Damani, L.A.4
  • 6
    • 1542693505 scopus 로고
    • Ph.D. thesis, University of London
    • 2-1,2,3-triazoline, Ph.D. thesis, University of London, 1994, pp. 169-178.
    • (1994) 2-1,2,3-triazoline , pp. 169-178
    • Stevenson, P.J.1
  • 7
    • 0001622059 scopus 로고
    • Triazoline decomposition
    • Thyagarajan, B. S. (ed). Wiley-Interscience, New York
    • Scheiner, P. Triazoline decomposition. In Thyagarajan, B. S. (ed). Selective Organic Transformations. Vol. I, Wiley-Interscience, New York, 1970, pp. 328-362.
    • (1970) Selective Organic Transformations , vol.1 , pp. 328-362
    • Scheiner, P.1
  • 9
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    • Triazolines 28. Identification of the triazoline pharmacophore and the evolution of the aminoalkylpyridines, a new class of potent orally active anticonvulsant agents
    • Deshmukh, T. R. and Kadaba, P. K. Triazolines 28. Identification of the triazoline pharmacophore and the evolution of the aminoalkylpyridines, a new class of potent orally active anticonvulsant agents. Med. Chem. Res. 3:223-232 (1993).
    • (1993) Med. Chem. Res. , vol.3 , pp. 223-232
    • Deshmukh, T.R.1    Kadaba, P.K.2
  • 10
    • 0029665798 scopus 로고    scopus 로고
    • 2-1,2,3-Triazoline anticonvulsants: Novel 'built in' heterocyclic prodrugs with a unique 'dual-action' mechanism for impairing excitatory amino acid L-glutamate neurotransmission
    • Accepted
    • 2-1,2,3-Triazoline anticonvulsants: novel 'built in' heterocyclic prodrugs with a unique 'dual-action' mechanism for impairing excitatory amino acid L-glutamate neurotransmission. Bioorg. Med. Chem. (Accepted).
    • Bioorg. Med. Chem.
    • Kadaba, P.K.1    Stevenson, P.J.2    Nnane, I.P.3    Damani, L.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.