Effects of interleukin 5-induced pulmonary eosinophilia on airway reactivity in the guinea pig

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 270, Issue 3 14-3, 1996, Pages

  Lilly, Craig M ^a   Chapman, Richard W ^b   Sehring, Susan J ^b   Mauser, Peter J ^b   Egan, Robert W ^b   Drazen, Jeffrey M ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NONE

Author keywords

asthma; cytokines; inflammation; lung disease

Indexed keywords

HISTAMINE; INTERLEUKIN 5; METHACHOLINE; RECOMBINANT INTERLEUKIN 5; SUBSTANCE P; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; EOSINOPHIL; EOSINOPHILIA; GUINEA PIG; INFLAMMATION; INTRATRACHEAL DRUG ADMINISTRATION; LUNG LAVAGE; LUNG PARENCHYMA; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION;

EID: 0029866838     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.270.3.l368     Document Type: Article

References (55)

1. Adelroth, E., L. Rosenhall, S. A. Johansson, M. Linden, and P. Venge. Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage. The effects of antiasthmatic treatment with budesonide or terbutaline. Am. Rev. Respir. Dis. 142: 91-99, 1990.
2. Ayars, G. H., L. C. Altman, M. M. McManus, J. M. Agosti, C. Baker, D. L. Luchtel, D. A. Loegering, and G. J. Gleich. Injurious effect of the eosinophil peroxide-hydrogen peroxidehalide system and major basic protein on human nasal epithelium in vitro. Am. Rev. Respir. Dis. 140: 125-131, 1989.
3. Beasley, R., W. R. Roche, J. A. Roberts, and S. T. Holgate. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am. Rev. Respir. Dis. 139: 806-817, 1989.
4. Bousquet, J., P. Chanez, J. Y. Lacoste, G. Barnéon, N. Ghavanian, I. Enander, P. Venge, S. Ahlstedt, J. Simony-Lafontaine, P. Godard, and F.-B. Michel. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323: 1033-1039, 1990.
5. Bradding, P., J. A. Roberts, K. M. Britten, S. Montefort, R. Djukanovic, R. Mueller, C. H. Heusser, P. H. Howarth, and S. T. Holgate. Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am. J. Respir Cell Mol. Biol. 10: 471-480, 1994.
6. Broide, D. H., and G. S. Firestein. Endobronchial allergen challenge in asthma: demonstration of cellular source of granulocyte macrophage colony-stimulating factor by in situ hybridization. J. Clin. Invest. 88: 1048-1053, 1991.
7. Broide, D. H., G. J. Gleich, A. J. Cuomo, D. A. Coburn, E. C. Federman, L. B. Schwartz, and S. I. Wasserman. Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J. Allergy Clin. Immunol. 88: 637-648, 1991.
8. Broide, D. H., M. M. Paine, and G. S. Firestein. Eosinophils express interleukin 5 and granulocyte macrophage-colonystimulating factor mRNA at sites of allergic inflammation in asthmatics. J. Clin. Invest. 90: 1414-1424, 1992.
9. Burke, C., C. K. Power, A. Norris, A. Condez, B. Schmekel, and L. W. Poulter. Lung function and immunopathological changes after inhaled corticosteroid therapy in asthma. Eur. Respir. J. 5: 73-79, 1992.
10. Dahinden, C. A., S. C. Bischoff, T. Brunner, M. Krieger, S. Takafuji, and A. L. De Weck. Regulation of mediator release by human basophils: importance of the sequence and time of addition in the combined action of different agonists. Int. Arch. Allergy Appl. Immunol. 94: 161-164, 1991.
11. Danko, G., J. A. Hey, R. W. Egan, W. Kreutner, and R. W. Chapman. Histamine H3 receptors inhibit sympathetic modula-tion of airway microvascular leakage in allergic guinea pigs. Eur. J. Pharmacol. 254: 283-286, 1994.
12. Desreumaux, P., A. Janin, S. Dubucquoi, M. C. Copin, G. Torpier, A. Capron, M. Capron, and L. Prin. Synthesis of interleukin-5 by activated eosinophils in patients with eosinophilic heart diseases. Blood 82: 1553-1560, 1993.
13. Diaz, P., M. C. Gonzalez, F. R. Galleguillos, P. Ancic, O. Cromwell, D. Shepherd, S. R. Durham, G. J. Gleich, and A. B. Kay. Leukocytes and mediators in bronchoalveolar lavage during allergen-induced late-phase asthmatic reactions. Am. Rev. Respir. Dis. 139: 1383-1389, 1989.
14. Djukanovic, R., J. W. Wilson, K. M. Britten, S. J. Wilson, A. F. Walls, W. R. Roche, P. H. Howarth, and S. T. Holgate. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am. Rev. Respir. Dis. 145: 669-674, 1992.
15. Dor, P. J., S. J. Ackerman, and G. J. Gleich. Charcot-Leyden crystal protein and eosinophil granule major basic protein in sputum of patients with respiratory diseases. Am. Rev. Respir. Dis. 130: 1072-1077, 1984.
16. Dubucquoi, S., P. Desreumaux, A. Janin, O. Klein, M. Goldman, J. Tavernier, A. Capron, and M. Capron. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J. Exp. Med. 179: 703-708, 1994.
17. Dunnill, M. S. The pathology of asthma, with special reference to changes in the bronchial mucosa. J. Clin. Pathol. 13: 27-33, 1960.
18. Ebisawa, M., T. Yamada, C. Bickel, D. Klunk, and R. P. Schleimer. Eosinophil transendothelial migration induced by cytokines. III. Effect of the chemokine RANTES. J. Immunol. 153: 2153-2160, 1994.
19. Filley, W. V., K. E. Holley, G. M. Kephart, and G. J. Gleich. Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet 2: 11-16, 1982.
20. Frigas, E., D. A. Loegering, G. O. Solley, G. M. Farrow, and G. J. Gleich. Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayo Clin. Proc. 56: 345-353, 1981.
21. Giles, K. W., and S. Myers. An improved diphenylamine method for the estimation of deoxyribonucleic acid. Nature Lond. 206: 93, 1965.
22. Gleich, G. J. The eosinophil and bronchial asthma: current understanding. J. Allergy Clin. Immunol. 85: 422-436, 1990.
23. Gulbenkian, A. R., X. Fernandez, W. Kreutner, M. Minnicozzi, A. S. Watnick, T. Kung, and R. W. Egan. Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224. Am. Rev. Respir. Dis. 142: 680-685, 1990.
24. Hamann, K. J., M. E. Strek, S. L. Baranowski, N. M. Munoz, F. S. Williams, S. R. White, A. Vita, and A. R. Leff Effects of activated eosinophils cultured from human umbilical cord blood on guinea pig trachealis. Am. J. Physiol. 265 (Lung Cell Mol. Physiol. 9): L301-L307, 1993.
25. Hisamatsu, K., T. Ganbo, T. Nakazawa, Y. Murakami, G. J. Gleich, K. Makiyama, and H. Koyama. Cytotoxicity of human eosinophil granule major basic protein to human nasal sinus mucosa in vitro. J. Allergy Clin. Immunol. 86: 52-63, 1990.
26. Hutson, P. A., M. K. Church, T. P. Clay, P. Miller, and S. T. Holgate. Early and late phase bronchoconstriction after allergen challenge of nonanesthetized guinea pigs. I. The association of disordered airway physiology to leukocyte infiltration. Am. Rev. Respir. Dis. 137: 548-557, 1988.
27. Iwama, T., H. Nagai, H. Suda, N. Tsuruoka, and A. Koda. Effect of murine recombinant interleukin-5 on the cell population in guinea-pig airways. Br. J. Pharmacol. 105: 19-22, 1992.
28. Iwama, T., H. Nagai, N. Tsuruoka, and A. Koda. Effect of murine recombinant interleukin-5 on bronchial reactivity in guinea-pigs. Clin. Exp. Allergy 23: 32-38, 1993.
29. Kay, A. B. Asthma and inflammation. J. Allergy Clin. Immunol. 87: 893-910, 1991.
30. Kitamura, T., T. Tange, T. Terasawa, S. Chiba, T. Kuwaki, K. Miyagawa, Y. F. Piao, K. Miyazono, A. Urabe, and F. Takaku. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J. Cell. Physiol. 140: 323-334, 1989.
31. Laitinen, L. A., M. Heino, A. Laitinen, T. Kava, and T. Haahtela. Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am. Rev. Respir. Dis. 131: 599-606, 1985.
32. Laitinen, L. A., A. Laitinen, and T. Haahtela. A comparative study of the effects of an inhaled corticosteroid. budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial. J. Allergy Clin. Immunol. 90: 32-42, 1992.
33. Lilly, C. M., G. Besson, E. Israel, I. W. Rodger, and J. M. Drazen. Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs. Am. J. Respir. Crit. Care Med. 149: 1175-1179, 1994.
34. Lilly, C. M., L. Kobzik, A. E. Hall, and J. M. Drazen. Effects of chronic airway inflammation on the activity and enzymatic inactivation of neuropeptides in guinea pig lungs. J. Clin. Invest. 93: 2667-2674, 1994.
35. Lilly, C. M., M. A. Martins, and J. M. Drazen. Peptidase modulation of vasoactive intestinal peptide pulmonary relaxation in tracheal superfused guinea pig lungs. J. Clin. Invest. 91: 235-243, 1993.
36. Martins, M. A., S. A. Shore, N. P. Gerard, C. Gerard, and J. M. Drazen. Peptidase modulation of the pulmonary effects of tachykinins in tracheal superfused guinea pig lungs. J. Clin. Invest. 85: 170-176, 1990.
37. Mauser,P. J., A. M. Pitman, X. Fernandez, S. K. Foran, G. K. Adams, W. Kreutner, R. W. Egan, and R. W. Chapman. Effects of an antibody to IL-5 in a monkey model of asthma. Am. J. Respir. Crit. Care Med. 152: 467-472, 1995.
38. Mauser, P. J., A. Pitman, A. Witt, X. Fernandez, J. Zurcher, T. Kung, H. Jones, A. S. Watnick, R. W. Egan, W. Kreutner, and G. K. Adams. Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma. Am. Rev. Respir. Dis. 148: 1623-1627, 1993.
39. McFadden, E. R., and I. A. Gilbert. Medical progress-asthma. N. Engl. J. Med. 327: 1928-1937, 1992.
40. Meurer, R., G. Van Riper, W. Feeney, P. Cunningham, D. Hora, Jr., M. S. Springer, D. E. Maclntyre, and H. Rosen. Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1 alpha, or human interleukin 8. J. Exp. Med. 178: 1913-1921, 1993.
41. Moqbel, R., G. M. Walsh, T. Nagakura, A. J. MacDonald, A. J. Wardlaw, Y. Iikura, and A. B. Kay. The effect of platelet-activating factor on IgE binding to, and IgE-dependent biological properties of, human eosinophils. Immunology 70: 251-257, 1990.
42. Motojima, S., E. Frigas, D. A. Loegering, and G. J. Gleich. Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am. Rev. Respir. Dis. 139: 801-805, 1989.
43. Ohnishi, T., H. Kita, D. Weiler, S. Sur, J. B. Sedgwick, W. J. Calhoun, W. W. Busse, J. S. Abrams, and G. J. Gleich. IL-5 is the predominant eosinophil-active cytokine in the antigeninduced pulmonary late-phase reaction. Am. Rev. Respir. Dis. 147: 901-907, 1993.
44. Ohno, I., R. G. Lea, K. C. Flanders, D. A. Clark, D. Banwatt, J. Dolovich, J. Denburg, C. B. Harley, J. Gauldie, and M. Jordana. Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1). J. Clin. Invest. 89: 1662-1668, 1992.
45. Parker, D. R., G. T. O'Connor, D. Sparrow, M. R. Segal, and S. T. Weiss. The relationship of nonspecific airway responsiveness and atopy to the rate of decline of lung function. The normative aging study. Am. Rev. Respir. Dis. 141: 589-594, 1990.
46. Pretolani, M., J. Lefort, D. Leduc, and B. B. Vargaftig. Effect of human recombinant interleukin-5 on in vitro responsiveness to PAF of lung from actively sensitized guinea-pigs. Br. J. Pharmacol. 106: 677-684, 1992.
47. Rijcken, B., J. P. Schouten, T. T. Mensinga, S. T. Weiss, K. Devries, and R. Vanderlende. Factors associated with bronchial responsiveness to histamine in a population sample of adults. Am. Rev. Respir. Dis. 147: 1447-1453, 1993.
48. Robinson, D., Q. Hamid, A. Bentley, S. Ying, A. B. Kay, and S. R. Durham. Activation of CD4+ T-cells, increased T(H2)-type cytokine messenger RNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J. Allergy Clin. Immunol. 92: 313-324, 1993.
49. Rothenberg, M. E., A. D. Luster, C. M. Lilly, J. M. Drazen, and P. Leder. Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung. J. Exp. Med. 181: 1211-1216, 1995.
50. Uchida, D. A., S. J. Ackerman, A. J. Coyle, G. L. Larsen, P. F. Weller, J. Freed, and C. G. Irvin. The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo. A comparison with polycations. Am. Rev. Respir. Dis. 147: 982-988, 1993.
51. Van Oosterhout, A. J., A. R. Ladenius, H. F. Savelkoul, I. Van Ark, K. C. Delsman, and F. P. Nijkamp. Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs. Am. Rev. Respir. Dis. 147: 548-552, 1993.
52. Weller, P. F. The immunobiology of eosinophils. N. Engl. J. Med. 324: 1110-1118, 1991.
53. Wong, D. T., R. B. Donoff, J. Yang, B. Z. Song, K. Matossian, N. Nagura, A. Elovic, J. McBride, G. Gallagher, and R. Todd. Sequential expression of transforming growth factors alpha and beta 1 by eosinophils during cutaneous wound healing in the hamster. Am. J. Pathol. 143: 130-142, 1993.
54. Wong, D. T., A. Elovic, K. Matossian, N. Nagura, J. McBride, M. Y. Chou, J. R. Gordon, T. H. Rand, S. J. Galli, and P. F. Weller. Eosinophils from patients with blood eosinophilia express transforming growth factor beta 1. Blood 78: 2702-2707, 1991.
55. Wong, D. T., P. F. Weller, S. J. Galli, A. Elovic, T. H. Rand, G. T. Gallagher, T. Chiang, M. Y. Chou, K. Matossian, and J. McBride. Human eosinophils express transforming growth factor alpha. J. Exp. Med. 172: 673-681, 1990.