Differential in vitro activities of ionophore compounds against Plasmodium falciparum and mammalian cells

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 3, 1996, Pages 602-608

  Gumila, Catherine ^a   Ancelin, Marie Laure ^a   Jeminet, Georges ^b   Delort, Anne Marie ^b   Miquel, Geneviève ^c   Vial, Henri J ^a  

^a UNIV MONTPELLIER   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 BROMOLASALOCID A; ALAMETHICIN; ALBORIXIN; ANTIBIOTIC X 14885A; ANTIMALARIAL AGENT; CALCIMYCIN; CATIONOMYCIN; GRAMICIDIN D; GRAMICIDIN S; GRISORIXIN; INDANOMYCIN; IONOMYCIN; IONOPHORE; LASALOCID; LONOMYCIN A; LYSOCELLIN; MONENSIN A; MONENSIN A LACTONE; MONENSIN A METHYL ETHER; MONENSIN DERIVATIVE; NARASIN A; NIGERICIN; NONACTIN; SALINOMYCIN; UNCLASSIFIED DRUG; VALINOMYCIN;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; LYMPHOBLAST; MACROPHAGE; MAMMAL CELL; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

EID: 0029866685     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.3.602     Document Type: Article

References (45)

1. Adovelande, J., B. Bastide, J. Delcze, and J. Schrevel. 1993. Cytosolic free calcium in Plasmodium falciparum-infected erythrocytes and the effect of verapamil - a cytofluorimetric study. Exp Parasitol. 76:247-258.
2. Albrecht-Gary, A. M., S. Blanc-Parasote, D. W. Boyd, G. Dauphin, G. Jeminet, J. Juillard, M. Prudhorame, and C. Tissier. 1989 X-148S5A: an ionophore closely related to calcimycin (A 23187). NMR, thermodynamic and kinetics studies of cation selectivity. J. Am. Chem. Soc. 111:8598-8609.
3. 2+. Can. J. Chem. 60:981-989.
4. Cabantchik, Z. I. 1990. Properties of permeation pathways induced in the human red cell membrane by malaria parasites. Blood Cells 16:421-432.
5. + glutamate efflux in rat liver mitochondria. J. Antibiot. 32:740-745.
6. Desjardins, R. E., C. J. Canfield, J. D. Hatnes, and J. D. Chulay. 1979. Quantitative assessment of antimicrobial activity in vitro by a semiautomated microdilution technique. Antimicrob. Agents Chemother 16:710-718.
7. Divo, A. A., T. G. Geary, and J. B. Jensen. 1985. Oxygen- and time-dependent effects of antibiotics and selected mitochondrial inhibitors on Plasmodium falciparum in culture Antimicrob. Agents Chemother. 27:21-27
8. Elford, B. C., G. M. Cowan, and D. J. P. Ferguson. 1995. Parasite-regulated membrane transport processes and metabolic control in malaria-infected erythrocytes. Biochem J 308:361-374.
9. Elliot, J. R., D. Needham, J. P. Dilger, and D. A. Haydon. 1983. The effects of bilayer thickness and tension on gramicidin single-channel lifetime. Biochim. Biophys. Acta 735:93-103.
10. Eytan, G. D., R. Broza, and Y. Shalitin, 1988. Gramicidin S and dodecelylamine induce leakage and fusion of membranes at micromolar concentrations. Biochim Biophys. Acta 937:387-397.
11. + selectivity and biological activity. Agric. Biol. Chem. 54:1149-1155.
12. Gero, A. M., and W. J. O'Sullivan. 1990. Purines and pyrimidines in malarial parasites. Blood Cells 16:467-484.
13. Ginsburg, H. 1986. Effects of red blood potassium and hypertonicity on the growth of Plasmoduim falcipanim in culture. Z. Parasitenkd. 72:185-199.
14. Ginsburg, H. 1994. Transport pathways in the malaria-infected erythrocyte. Their characterization and their use as potential targets for chemotherapy. Biochem. Pharmacol. 48:1847-1856.
15. Goodrich, R. D., J. E. Garrett, D. R. Gast, M. A. Kirick, D. A. Larson, and J. C. Meiske. 1984 Influence of monensin on the performance of cattle. J. Anim. Sci. 58:1484-1497
16. Izumiya, N., T. Kato, H. Aoyagi, M. Waki, and M. Kondo. 1979. Synthetic aspects of biologically active cyclic peptides-gramicidin S and lyrocidines. Halsted, New York.
17. Jensen, J. B., and W. Trager. 3977 Plasmodium falciparum in culture: use of out dated erythrocytes and description of the candle-jar method. J. Parasitol. 63:883-886.
18. Juillard, J., C. Tissier, and G. Jeminet. 1988. Interactions between metal cations and the ionophore lasalocid J. Chem. Soc. Faraday Trans, 1 84:951-958.
19. Killian, J. A. 1992. Gramicidin and gramiddin-lipid interactions. Biochim. Biophys. Acta 1113:391-425.
20. Kovac, L., V. Poliachova, and I. Horrath. 1982. Ionophores and intact cells. I Valinomycin and nigericin act preferentially on mitochondria and not on the plasma membrane of Saccharomyces cerevisae. Biochim Biophys. Acta 721:341-348.
21. Kramer, R., and H. Ginsburg. 1991. Calcium transport and compartment analysis of free and exchangeable calcium in Plasmodium falciparum-infected red blood cells J Protozool. 38:594-601.
22. Krogstad, D. J., S. P. Sutera, J. S. Marvel, I. Y. Gluzman, C. W. Boylan, J. R. Colca, J. R. Williamson. and P. H. Schlesinger. 1991 Calcium and the malaria parasite: parasite maturation and the loss of red cell deformability. Blood Cells 17:229-241
23. Lee, P., Z. Ye, K. Van Dyke, and G. Kirk. 1988. X-ray microanalysis of Plasmodium falciparum and infected red blood cells: effects of qinghaosu and chloroquine on potassium, sodium, and phosphorus composition. J. Trop. Med. Hyg. 39:157-165.
24. McColm, A. A., and N. McHardy. 1984. Evaluation of a range of antimicrobial agents against the parasitic protozoa, Plasmodium falciparum, Babesia rodhaint and Theileria parva in vitro. Ann. Trop. Med. Parasitol. 78:345-354
25. Mikkelsen, R. B., K. Tanabe, and D. F. Wallach. 1982. Membrane potential of Plasmodium-infected erythrocytes. J. Cell Biol. 93:685-689.
26. Mikkelsen, R. B., D. F. H. Wallach, E. Van Doren, and E. A. Nillni. 1986. Membrane potential of erythrocytic stages of Plasmodium chabaudi free of the host cell membrane. Mol. Biochem. Parasitol. 21:83-92.
27. Moll, G. N., V. van den Eertwegh, H. Tournois, B. Roelofsen, J. A. F. Op den Kamp, and L. L. M. van Deenen. 1991. Growth inhibition of Plasmodium falciparum in in vitro cultures by selective action of tryptophan-N-formylated gramicidin incorporated in lipid vesicles Biochim. Biophys. Acta 1062:206-210.
28. 2 in vitro Biochim. Biophys Acta 1024:189-192
29. Ovchinnikov, Y. A. 1979. Physico-chemical basis of ion transport through biological membranes, ionophores and ion channels. Eur J. Biochem 94: 321-336.
30. Pressman, B. C. 1976. Biological applications of ionophores Annu. Rev. Biochem. 45:501-530.
31. Raether, W., H. Seidenath, H. Mehlhom, and H. J. Ganster. 1985. The action of salinomycin-Na and lasalocid-Na on chloroquine- and mepacrine-resistant line of Plasmodium berghei K 173-strain in Wistar rats. Z. Parasitenkd. 71:567-574
32. Richards, W. H., and B. K. Mapples. 1977. Studies on Plasmodium falciparum in continuous culture. I. The effects of chloroquine and pyrimethaminc on parasite growth. Ann Trop. Med Parasitol. 73:93-108
33. Roth, E. J. 1990. Plasmodium falciparum carbohydrate metabolism: a connection between host cell and parasite. Blood Cells 16:453-460.
34. Sansom, M. S. P. 1993. Alamcthicin and related peptaibols-model ion channels. Eur Biophys. J. 22:105-124.
35. Shechter, E. 1990. Lipides membranaires, p 9-29 In S. A. Massen (ed). Biochimie et biophysique des membranes Aspects structuraux et fonctionnels. E. Shechter, Paris.
36. Shumard, R. F., and M. E. Callender. 1968 Monensin, a new biologically active compound. VI. Anticoccidial activity. p 369-377 Antimicrob. Agents Chemother. 1967
37. Tanabe, K. 1990. Ion metabolism in malaria-infected erythrocytes. Blood Cells 16:437-449.
38. Tanabe, K., and S. Doi. 1989. Rapid clearance of Plasmodium yoelii-infected erythrocytes after exposure to the ionophore A23187. Comp Biochem. Physiol 92:85-89
39. Ubukata, M., T. Akama, and K. Isono. 1986. Chemical modification of cationomycin and its structure-activity relationship. Agric. Biol. Chem. 50; 1153-1160.
40. Vial, H. J., and M. L. Ancelin. 1992. Malarial lipids an overview, p. 259-306. In J. L. Avila and J. R. Harris (ed.), Subcellular biochemistry, vol. 18. Intracellular parasites. Plenum Press, New York.
41. Vial, H. J., M. J. Thuet, and J. R. Philippot. 1982. Inhibition of the in vitro growth of Plasmodium falciparum by D vitamins and vitamin D-3 derivatives. Mol. Biochem. Parasitol. 5:189-198.
42. 2+ depletion on the asexual cell cycle of Plasmodium falciparum. Am. J. Trop. Med. Hyg. 31:711-717.
43. Westley, J. W. 1982. Polyethers antibiotics: naturally occuring acid ionophores. In J. W. Westley (ed.), Biology, vol 1. Marcel Dekker, Inc., New York.
44. Westley, J. W., E. P. Oliveto, J. Berger, R. M. Evans, R. Glass, A. Stempel, V. Toome, and T. Williams. 1973. Chemical transformations of antibiotic X-534A and their effect on antibacterial activity. J. Med. Chem. 16:397-403.
45. Woolley, G. A., and B. A. Wallace. 1992. Model ion channels: gramicidin and alamethicin. J. Membr. Biol. 129:109-136.