Prospective study of increased platelet membrane fluidity as a risk factor for Alzheimer's disease: Results at 5 years

American Journal of Psychiatry

Volumn 153, Issue 3, 1996, Pages 420-423

  Zubenko, George S ^a   Teply, Ivana ^b   Winwood, Ethel ^b   Huff, F Jacob ^b   Moossy, John ^b   Sunderland, Trey ^b   Martinez, A Julio ^b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; FOLLOW UP; HIGH RISK POPULATION; HUMAN; INCIDENCE; LONGITUDINAL STUDY; MENTAL HEALTH; PRIORITY JOURNAL; PROSPECTIVE STUDY; RATING SCALE; RISK FACTOR; THROMBOCYTE MEMBRANE;

EID: 0029866559     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.153.3.420     Document Type: Article

References (24)

1. Zubenko GS: Biological correlates of clinical heterogeneity in primary dementia. Neuropsychopharmacology 1992; 6(suppl 2): 77-93
2. Sweet RA, Zubenko GS: Peripheral markers in Alzheimer's disease, in Dementia. Edited by Burns A, Levy R. London, Chapman & Hall, 1994, pp 387-403
3. Hicks N, Brammer MJ, Hymas N, Levy R: Platelet membrane properties in Alzheimer and multi-infarct dementias. Alzheimer Dis Assoc Disord 1987; 1(suppl 2):90-97
4. Hajimohammadreza I, Brammer MJ, Eagger S, Burns A, Levy R: Platelet and erythrocyte membrane changes in Alzheimer's disease. Biochim Biophys Acta 1990; 1025:208-214
5. Eagger S, Hajimohammadreza I, Fletcher K, Levy R, Brammer M: Platelet membrane fluidity, family history, and severity and age of onset in Alzheimer's disease. Int J Geriatr Psychiatry 1990; 5:395-400
6. Piletz JE, Sarasua M, Whitehouse P, Chotani M: Intracellular membranes are more fluid in platelets of Alzheimer's disease patients. Neurobiol Aging 1991; 12:401-406
7. van Rensburg SJ, Carstens ME, Potocnik FCV, Aucamp AK, Taljaard JF, Koch KR: Membrane fluidity of platelets and erythrocytes in patients with Alzheimer's disease and the effect of small amounts of aluminum on platelet and erythrocyte membranes. Neurochem Res 1992; 17:825-829
8. Kálmán J, Dey I, Ilona SV, Matkovics B, Brown D, Janka Z, Farkas T, Joó F: Platelet membrane fluidity and plasma malon-dialdehyde levels in Alzheimer's demented patients with and without family history of dementia. Biol Psychiatry 1994; 35: 190-194
9. Kukull WA, Hinds TR, Schellenberg GD, van Belle G, Larson EB: Increased platelet membrane fluidity as a diagnostic marker for Alzheimer's disease: a test in population-based cases and controls. Neurology 1992; 42:607-614
10. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34:939-944
11. Folstein MF, Folstein SE, McHugh PR: "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12:189-198
12. Zubenko GS, Cohen BM, Reynolds CF III, Boller F, Malinakova I, Keefe N: Platelet membrane fluidity in Alzheimer's disease and major depression. Am J Psychiatry 1987; 144:860-868
13. Mattis S: Mental status examination for organic mental syndrome in the elderly patient, in Geriatric Psychiatry. Edited by Bellak L, Kanasu TB. New York, Grune & Stratton, 1976, pp 77-121
14. Zuhenko GS, Huff FJ, Beyer J, Auerbach J, Teply I: Familial risk of dementia associated with a biologic subtype of Alzheimer's disease. Arch Gen Psychiatry 1988; 45:889-893
15. Huff FJ, Auerbach J, Chakravarti A, Boller F: Risk of dementia in relatives of patients with Alzheimer's disease. Neurology 1988; 38:786-790
16. Tomlinson BE, Corsellis JAN: Aging and the dementias, in Greenfield's Neuropathology, 4th ed. Edited by Adams HJ, Corsellis JAN, Duchen LW. New York, John Wiley & Sons, 1984, pp 951-1025
17. Khachaturian ZS: Diagnosis of Alzheimer's disease. Arch Neurol 1985; 42:1097-1105
18. Hagnell O, Öjesjö L, Rorsman B: Incidence of dementia in the Lundby study. Neuroepidemiology 1992; 11:61-66
19. Letenneur L, Hacqmin H, Commenges D, Barberger-Gateau P, Dartigues J-F, Salamon R: Cerebral and functional aging: first results of prevalence and incidence of the Paquid cohort. Methods Inf Med 1993; 32:249-251
20. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Statistical Assoc 1958; 53:457-481
21. Heston LL, Mastri AR, Anderson VE, White J: Dementia of the Alzheimer type: clinical genetics, natural history, and associated conditions. Arch Gen Psychiatry 1981; 38:1085-1090
22. Heyman A, Wilkinson WE, Hurwitz BJ, Schmechel D, Sigmon AH, Weinberg T, Helms MJ, Swift M: Alzheimer's disease: genetic aspects and associated clinical disorders. Ann Neurol 1983; 14:507-515
23. Mohs RC, Breitner JCS, Silverman JM, Davis KL: Alzheimer's disease: morbid risk among first-degree relatives approximates 50% by 90 years of age. Arch Gen Psychiatry 1987; 44:405-408
24. Amaducci L, Lippi A: Risk factors for dementia, in Dementia. Edited by Burns A, Levy R. London, Chapman & Hall, 1994, pp 129-141