메뉴 건너뛰기




Volumn 7, Issue 1, 1996, Pages 69-79

Effects of inogatran, a new low-molecular-weight thrombin inhibitor, in rat models of venous and arterial thrombosis, thrombolysis and bleeding time

Author keywords

Animal models; Anticoagulant agents; Argatroban; Arterial thrombosis; Bleeding time; Heparin; Inogatran; Thrombolysis; Venous thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; ANTICOAGULANT AGENT; ARGATROBAN; HEPARIN; INOGATRAN; LYSINE ACETYLSALICYLATE; SLONON; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 0029866371     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-199601000-00009     Document Type: Article
Times cited : (49)

References (27)
  • 1
    • 0013651390 scopus 로고
    • Operative venous dilatation and its relationship to postoperative deep vein thrombosis
    • Bergqvist D, Comerota AJ, Nicolaides AN, Scurr JH, eds. Nicosia: Med-Orion Publishing Company
    • Comerota AJ. Operative venous dilatation and its relationship to postoperative deep vein thrombosis. In: Bergqvist D, Comerota AJ, Nicolaides AN, Scurr JH, eds. Prevention of Venous Thromboembolism. Nicosia: Med-Orion Publishing Company, 1994: 31-41.
    • (1994) Prevention of Venous Thromboembolism , pp. 31-41
    • Comerota, A.J.1
  • 2
    • 0027409404 scopus 로고
    • A player of many parts: The spotlight falls on thrombin's structure
    • Stubbs MT, Bode W. A player of many parts: the spotlight falls on thrombin's structure. Thromb Res 1993; 69: 1-58.
    • (1993) Thromb Res , vol.69 , pp. 1-58
    • Stubbs, M.T.1    Bode, W.2
  • 3
    • 0026337077 scopus 로고
    • The coagulation cascade: Initiation, maintenance, and regulation
    • Davie EW, Fujikawa K, Kisiel W. The coagulation cascade: initiation, maintenance, and regulation. Biochem 1991; 30: 10363-10370.
    • (1991) Biochem , vol.30 , pp. 10363-10370
    • Davie, E.W.1    Fujikawa, K.2    Kisiel, W.3
  • 4
    • 0002675554 scopus 로고
    • Prothrombin and thrombin
    • Colman RW, Hirsch J, Marder VJ, Salzman EW, eds. Philadelphia: JB Lippincott
    • Mann KG. Prothrombin and thrombin. In: Colman RW, Hirsch J, Marder VJ, Salzman EW, eds. Haemostasis and Thrombosis: Basic Principles and Clinical Practice. Philadelphia: JB Lippincott, 1994: 184-199.
    • (1994) Haemostasis and Thrombosis: Basic Principles and Clinical Practice , pp. 184-199
    • Mann, K.G.1
  • 5
    • 0028268712 scopus 로고
    • Guide to anticoagulant therapy. Part 2: Oral anticoagulants
    • Hirsh J, Fuster V. Guide to anticoagulant therapy. Part 2: Oral anticoagulants. Circulation 1994; 89: 1469-1480.
    • (1994) Circulation , vol.89 , pp. 1469-1480
    • Hirsh, J.1    Fuster, V.2
  • 6
    • 0026707776 scopus 로고
    • Hemorrhagic complications of anticoagulant treatment
    • Levine MN, Hirsh J, Landefeld S, Raskob G. Hemorrhagic complications of anticoagulant treatment. Chest 1992; 102: 352S-363S.
    • (1992) Chest , vol.102
    • Levine, M.N.1    Hirsh, J.2    Landefeld, S.3    Raskob, G.4
  • 7
    • 0027968823 scopus 로고
    • The development of hirudin as an antithrombotic drug
    • Markwardt F. The development of hirudin as an antithrombotic drug. Thromb Res 1994; 74: 1-23.
    • (1994) Thromb Res , vol.74 , pp. 1-23
    • Markwardt, F.1
  • 8
    • 0026347092 scopus 로고
    • Argatroban, a selective, potent thrombin inhibitor
    • Bush LR. Argatroban, a selective, potent thrombin inhibitor. Cardiovasc Drug Rev 1991; 9: 247-263.
    • (1991) Cardiovasc Drug Rev , vol.9 , pp. 247-263
    • Bush, L.R.1
  • 9
    • 0022501549 scopus 로고
    • A sensitive model of venous thrombosis in rats
    • Hladovec J. A sensitive model of venous thrombosis in rats. Thromb Res 1986; 43: 539-544.
    • (1986) Thromb Res , vol.43 , pp. 539-544
    • Hladovec, J.1
  • 10
  • 11
    • 0025614358 scopus 로고
    • Rat model of arterial thrombosis induced by ferric chloride
    • Kurz KD, Main BW, Sandusky GE. Rat model of arterial thrombosis induced by ferric chloride. Thromb Res 1990; 60: 269-280.
    • (1990) Thromb Res , vol.60 , pp. 269-280
    • Kurz, K.D.1    Main, B.W.2    Sandusky, G.E.3
  • 12
    • 0027462171 scopus 로고
    • A new rat model of arterial thrombosis with a platelet-rich head and an erythrocyterich tail: Thrombolysis experiments with specific thrombin inhibition
    • Lenfors S, Marberg L, Wikström S, Jonsson U, Westin-Eriksson A, Gustafsson D. A new rat model of arterial thrombosis with a platelet-rich head and an erythrocyterich tail: thrombolysis experiments with specific thrombin inhibition. Blood Coag Fibrinol 1993; 4: 263-271.
    • (1993) Blood Coag Fibrinol , vol.4 , pp. 263-271
    • Lenfors, S.1    Marberg, L.2    Wikström, S.3    Jonsson, U.4    Westin-Eriksson, A.5    Gustafsson, D.6
  • 13
    • 0018745986 scopus 로고
    • Bleeding time in laboratory animals. II - A comparison of different assay conditions in rats
    • Dejana E, Callioni A, Quintana A, de Gaetano G. Bleeding time in laboratory animals. II - A comparison of different assay conditions in rats. Thromb Res 1979; 15: 191-197.
    • (1979) Thromb Res , vol.15 , pp. 191-197
    • Dejana, E.1    Callioni, A.2    Quintana, A.3    De Gaetano, G.4
  • 14
    • 0013606477 scopus 로고
    • Venous stasis and trauma in hip surgery
    • Bergqvist D, Comerota AJ, Nicolaides AN, Scurr JH, eds. Nicosia: Med-Orion Publishing Company
    • Planes A, Vochelle N. Venous stasis and trauma in hip surgery. In: Bergqvist D, Comerota AJ, Nicolaides AN, Scurr JH, eds. Prevention of Venous Thromboembolism. Nicosia: Med-Orion Publishing Company, 1994: 57-62.
    • (1994) Prevention of Venous Thromboembolism , pp. 57-62
    • Planes, A.1    Vochelle, N.2
  • 15
    • 0025822388 scopus 로고
    • The effects of recombinant desulphatohirudin on arterial thrombosis in rats
    • Talbot MD, Ambler J, Butler KD, et al. The effects of recombinant desulphatohirudin on arterial thrombosis in rats. Haemost 1991; 21: 73-79.
    • (1991) Haemost , vol.21 , pp. 73-79
    • Talbot, M.D.1    Ambler, J.2    Butler, K.D.3
  • 16
    • 0028004409 scopus 로고
    • Antithrombotic actions of argatroban in rat models of venous, 'mixed' and arterial thrombosis, and its effects on the tail transection bleeding time
    • Berry CN, Girard D, Lochot S, Lecoffre C. Antithrombotic actions of argatroban in rat models of venous, 'mixed' and arterial thrombosis, and its effects on the tail transection bleeding time. Br J Pharmacol 1994; 113: 1209-1214.
    • (1994) Br J Pharmacol , vol.113 , pp. 1209-1214
    • Berry, C.N.1    Girard, D.2    Lochot, S.3    Lecoffre, C.4
  • 17
    • 0028353572 scopus 로고
    • Guide to anticoagulant therapy. Part 1: Heparin
    • Hirsh J, Fuster V. Guide to anticoagulant therapy. Part 1: Heparin. Circulation 1994; 89: 1449-1468.
    • (1994) Circulation , vol.89 , pp. 1449-1468
    • Hirsh, J.1    Fuster, V.2
  • 18
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition of heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • Weitz JJ, Hudoba M, Hassel D, Marganore J, Hirsch J. Clot-bound thrombin is protected from inhibition of heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. J Clin Invest 1990; 86: 385-391.
    • (1990) J Clin Invest , vol.86 , pp. 385-391
    • Weitz, J.J.1    Hudoba, M.2    Hassel, D.3    Marganore, J.4    Hirsch, J.5
  • 19
    • 0024670167 scopus 로고
    • Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: Implications for heparin efficacy
    • Hogg PJ, Jackson CM. Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy. Proc Natl Acad Sci USA 1989; 86: 3619-3623.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3619-3623
    • Hogg, P.J.1    Jackson, C.M.2
  • 20
    • 0018198558 scopus 로고
    • Properties of the factor Xa binding site on human platelets
    • Miletich JP, Jackson CM, Majerus PW. Properties of the factor Xa binding site on human platelets. J Biol Chem 1978; 253: 6908-6916.
    • (1978) J Biol Chem , vol.253 , pp. 6908-6916
    • Miletich, J.P.1    Jackson, C.M.2    Majerus, P.W.3
  • 21
    • 0022049305 scopus 로고
    • Biochemistry of alpha granule proteins
    • Holt JC, Niewiarowski S. Biochemistry of alpha granule proteins. Semin Hematol 1985; 22:151-163.
    • (1985) Semin Hematol , vol.22 , pp. 151-163
    • Holt, J.C.1    Niewiarowski, S.2
  • 22
    • 0027240597 scopus 로고
    • An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigators
    • Anonymous. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigators. N Engl J Med 1993; 329: 673-682.
    • (1993) N Engl J Med , vol.329 , pp. 673-682
  • 23
    • 0001992016 scopus 로고
    • In vitro properties of inogatran, a new selective low molecular weight inhibitor of thrombin
    • Teger-Nilsson AC, Gyzander E, Andersson S, et al. In vitro properties of inogatran, a new selective low molecular weight inhibitor of thrombin. Thromb Haemost 1995; 73: 1325.
    • (1995) Thromb Haemost , vol.73 , pp. 1325
    • Teger-Nilsson, A.C.1    Gyzander, E.2    Andersson, S.3
  • 24
    • 0029059195 scopus 로고
    • Novel antithrombotic drugs in development
    • Verstraete M, Zoldhelyi P. Novel antithrombotic drugs in development. Drugs 1995; 49: 856-884.
    • (1995) Drugs , vol.49 , pp. 856-884
    • Verstraete, M.1    Zoldhelyi, P.2
  • 26
    • 0025371762 scopus 로고
    • Bleeding time and other laboratory tests to monitor the safety and efficacy of thrombolytic therapy
    • Hirsch DR, Goldhaber SZ. Bleeding time and other laboratory tests to monitor the safety and efficacy of thrombolytic therapy. Chest 1990; 97: 124S-131S.
    • (1990) Chest , vol.97
    • Hirsch, D.R.1    Goldhaber, S.Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.