Unprimed T cells are inefficiently stimulated by glycosylphosphatidylinositol-linked H-2Kb because of its lipid anchor rather than defects in CD8 binding

International Immunology

Volumn 8, Issue 4, 1996, Pages 551-557

  Zamoyska, Rose ^b   Ong, Tim ^b   Kwan Lim, Gek ^b   Tomlinson, Peter ^b   Robinson, Peter J ^a  

^a MRC CLINICAL SCIENCES CENTRE   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Class Ib MHC molecules; Cytotoxic T cells; Glycophosphatidylinositol membrane anchors; Qa 2; T cell hybridomas

Indexed keywords

CD8 ANTIGEN; GLYCOSYLPHOSPHATIDYLINOSITOL; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; T LYMPHOCYTE RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD8; GENE EXPRESSION REGULATION; GLYCOSYLPHOSPHATIDYLINOSITOLS; H-2 ANTIGENS; HYBRIDOMAS; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION;

EID: 0029866279     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.4.551     Document Type: Article

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