Effects of permanent eradication or transient clearance of Helicobacter pylori on histology of gastric mucosa using omeprazole with or without antibiotics

Scandinavian Journal of Gastroenterology, Supplement

Volumn 31, Issue 215, 1996, Pages 105-110

  Solcia, E ^a   Fiocca, R ^b   Villani, L ^b   Carlsson, J ^b   Rudback A ^b   Zeijlon, L ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b NONE

Author keywords

Amoxycillin; Bacterial eradication; Gastritis activity; Helicobacter pylori gastritis; Omeprazole; Uulcerogenesis

Indexed keywords

AMOXICILLIN; OMEPRAZOLE; PLACEBO; ANTIINFECTIVE AGENT; ANTIULCER AGENT;

CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ERADICATION THERAPY; FEMALE; GASTRITIS; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; STOMACH MUCOSA; ULCEROGENESIS; ARTICLE; BIOPSY; COMPARATIVE STUDY; DRUG COMBINATION; DUODENUM ULCER; HELICOBACTER INFECTION; MICROBIOLOGY; PATHOLOGY; RECURRENT DISEASE; TIME;

AMOXICILLIN; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; BIOPSY; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; DUODENAL ULCER; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; OMEPRAZOLE; RECURRENCE; TIME FACTORS;

EID: 0029866206     PISSN: 00855928     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365529609094545     Document Type: Conference Paper

References (18)

1. Unge P, Gad A, Eriksson K, Bergman B, Carling L, Ekström P, et al. Amoxicillin added to omeprazole prevents relapse in the treatment of duodenal ulcer patients. Eur J Gastroenterol Hepatol 1993;5:325-31.
2. Solcia E, Villani L, Fiocca R, Luinetti O, Boldorini R, Trespi E, et al. Effect of eradication of Helicobacter pylori on gastritis in duodenal ulcer patients. Scand J Gastroenterol 1994;29 Suppl 201:28-34.
3. Bianchi Porro G, Lazzaroni M, Bargiggia S, Maconi G, Trespi E, Perego M, et al. Evaluation of omeprazole coupled with two antibiotics on Helicobacter pylori eradication and duodenal ulcer recurrence. Gastroenterology 1995;108:A59.
4. Price AB. The Sydney system: histological division. Eur J Gastroenterol Hepatol 1991;6:209-22.
5. Genta RM, Lew GM, Graham DY. Changes in the gastric mucosa following eradication of Helicobacter pylori. Mod Pathol 1993;6:281-9.
6. Cover TL, Vaughn SG, Cao P, Blaser MJ. Potentiation of Helicobacter pylori vacuolating toxin activity by nicotine and other weak bases. J Infect Dis 1992;166:1075-8.
7. Ricci V, Sommi P, Fiocca R, Cova E, Figura N, Romano M, et al. Cytotoxicity of Helicobacter pylori on human gastric epithelial cells in vitro: role of cytotoxins and ammonia. Eur J Gastroenterol Hepatol 1993;5:687-94.
8. Crabtree JE, Shallcross TM, Heatley RV, Wyatt JI. Mucosal tumor necrosis factor alpha and interleukin-6 in patients with Helicobacter associated gastritis. Gut 1991;32:1473-7.
9. Fiocca R, Luinetti O, Villani L, Chiaravalli M, Capella C, Solcia E. Epithelial cytotoxicity, immune responses, and inflammatory components of Helicobacter pylori gastritis. Scand J Gastro-enterol 1994;29 Suppl 205:11-21.
10. Fiocca R, Villani L, Luinetti O, Gianetti A, Perego M, Alvisi C, et al. Helicobacter colonization and histopathological profile of chronic gastritis in patients with or without dyspepsia, mucosal erosion and peptic ulcer: a morphological approach to the study of ulcerogenesis in man. Virchows Arch A Pathol Anat Histopathol 1992;420:489-98.
11. Fiocca R, Luinetti O, Villani L, Chiaravalli A, Cornaggia M, Stella G, et al. High incidence of Helicobacter pylori colonization in early gastric cancer and the possible relationship to carcinogenesis. Eur J Gastroenterol Hepatol 1993;5 Suppl 2:S2-S8.
12. Frieri G, De Petris G, Ligas E, Santarelli D, Aggio A, Rosoni R, et al. Gastric mucosal pH in H. pylori infected normal subjects. Ital J Gastroenterol 1991;23 Suppl 2:88-9.
13. Stolte M, Bethke B, Blum AL, Sulser E, Stadelmann O. Antacid treatment has a deleterious effect on the severity and activity of gastritis of the corpus mucosa. Ir J Med Sci 1992;161 Suppl 10:6.
14. Dent J, Yeomans ND, Mackinnon M, Reed W, Narielvala FM, Hetzel DJ, et al. Omeprazole versus ranitidine for prevention of relapse in reflux esophagitis. A controlled double-blind trial of their efficacy and safety. Gut 1994;35:590-8.
15. Saita H, Murakami M, Dekigai H, Kusaka S, Asagoe K, Shigemoto K, et al. Suppression of acid secretion increases ammonia induced gastric damage. Gastroenterology 1995; 108:A207.
16. Lamberts R, Creutzfeldt W, Struber HG, Brunner G, Solcia E. Long-term omeprazole therapy in peptic ulcer disease: gastrin, endocrine cell growth, and gastritis. Gastroenterology 1993; 104:1356-70.
17. Kuipers EJ, Klinkenberg-Knol EC, Havu N, Festen HPM, Lamers CBHW, Jansen JBMJ, et al. Helicobacter pylori and development of atrophic gastritis during omeprazole maintenance therapy. Gastroenterology 1995;108:A137.
18. Hitchcock CR, Sullivan WA, Wangensteen OH. The value of achlorhydria as a screening test for gastric cancer. Gastroenterology 1995;29:621-32.