Minocycline impairment of both osteoid tissue removal and osteoclastic resorption in a synchronized model of remodeling in the rat

Journal of Cellular Physiology

Volumn 167, Issue 2, 1996, Pages 359-368

  Klapisz Wolikow, M ^a   Saffar, J L ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; MINOCYCLINE; TETRACYCLINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MATRIX; BONE MINERALIZATION; CONTROLLED STUDY; DRUG EFFECT; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; MORPHOMETRICS; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; BONE REMODELING; BONE RESORPTION; COLLAGENASES; KINETICS; MALE; MINOCYCLINE; OSTEOCLASTS; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0029866199     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199605)167:2<359::AID-JCP22>3.0.CO;2-1     Document Type: Article

References (63)

1. Auszmann, J., Kleckner, A., Vernillo, A., and Rifkin, B. (1992) Effects of tetracycline on osteoclast cathepsin L activity. J. Dent. Res., 71:757 (abstract).
2. Baron, R., Tran Van, P., Nefussi, J.R., and Vignery, A. (1986) Kinetic and cytochemical identification of osteoclast precursors and their differentiation into multinucleated osteoclasts. Am. J. Pathol., 122:363-378.
3. 2+ receptor activation. Biosci. Rep., 13:169-174.
4. Chambers, T.J., Thomson, D.M., and Fuller, K. (1984) Effect of substrate composition on bone resorption by rabbit osteoclasts. J. Cell Sci., 70:61-71.
5. Chambers, T.J., Darby, J.A., and Fuller, K. (1985) Mammalian collagenase predisposes bone surfaces to osteoclastic resorption. Cell Tissue Res., 241:671-675.
6. Chang, K.M., Ramamurthy, N.S., McNamara, T.F., Evans, R.T., Klausen, B., Murray, P.A., and Golub, L.M. (1994) Tetracyclines inhibit Porphyromonas gingivalis-induced alveolar bone loss in rats by a non-antimicrobial mechanism. J. Period. Res., 29:242-249.
7. Chow, J., and Chambers, T.J. (1992) An assessment of the prevalence of organic material on bone surfaces. Calcif. Tissue Int., 50:118-122.
8. Clohisy, J.C., Connolly, T.J., Bergman, K.D., Quinn, C.O., and Partridge, N.C. (1994) Prostanoid-induced expression of matrix metalloproteinase-1 messenger ribonucleic acid in rat osteosarcoma cells. Endocrinology, 135:1447-1454.
9. Cohen-Solal, M., Morieux, C., and de Vernejoul, M.C. (1991a) Relationship between the number of resorbing cells and the amount resorbed in metabolic bone disorders, J. Bone Miner. Res., 6:915-920.
10. Cohen-Solal, M.E., Shih, M.S., Lundy, M.W., and Parfitt, A.M. (1991b) A new method for measuring cancellous bone erosion depth - application to the cellular mechanisms of bone loss in postmenopausal osteoporosis. J. Bone Miner. Res., 6:1331-1338.
11. Connolly, T.J., Clohisy, J.C., Shilt, J.S., Bergman, K.D., Partridge, N.C., and Quinn, C.O. (1994) Retinoic acid stimulates interstitial collagenase messenger ribonucleic acid in osteosarcoma cells. Endocrinology, 135:2542-2548.
12. Datta, H.K., MacIntyre, I., and Zaidi, M. (1989) The effect of extracellular calcium elevation on morphology and function of isolated rat osteoclasts. Biosci. Rep., 9:747-751.
13. Delaissé, J.M., Eeckhout, Y., Sear, C., Galloway, A., McCullagh, K., and Vaes, G. (1985) A new synthetic inhibitor of mammalian tissue collagenase inhibits bone resorption in culture. Biochem. Biophys. Res. Commun., 133:483-490.
14. Delaissé, J.M., Eeckhout, Y., and Vaes, G. (1988) Bone-resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue. Endocrinology, 123:264-276.
15. 3H-tetracycline retention in bones of prelabelled mice. Bone, 12:289 (abstract).
16. Delaissé, J.M., Eeckhout, Y., Neff, L., Francois-Gillet, C., Henriet, P., Su, Y., Vaes, G., and Baron, R. (1993) (Pro)Collagenase (matrix metalloproteinase-1) is present in rodent osteoclasts and in the underlying bone-resorbing compartment. J. Cell Sci., 106:1071-1082.
17. Dobigny, C., and Saffar, J.L. (1991) Partial inhibition of bone resorption by disodium cromoglycate in a synchronized model of bone remodeling. Agents Actions, 33:326-329.
18. Donahue, H.J., Iijima, K., Goligorsky, M.S., Rubin, C.T., and Rifkin, B.R. (1992) Regulation of cytoplasmic calcium concentration in tetracycline-treated osteoclasts. J. Bone Miner. Res., 7:1313-1318.
19. Everts, V., Delaissé, J.M., Korper, W., Niehof, A., Vaes, G., and Beertsen, W. (1992) Degradation of collagen in the bone-resorbing compartment underlying the osteoclast involves both cysteine-proteinases and matrix metalloproteinases. J. Cell. Physiol., 150:221-231.
20. Franchi-Miller C., and Saffar J.L. (1995) The 5-lipoxygenase inhibitor BWA4C impairs osteoclastic resorption in a synchronized model of bone remodeling. Bone, 17:185-191.
21. Golub, L.M., Lee, H.M., Lehrer, G., Nemiroff, A., McNamara, T.F., Kaplan, R., and Ramamurthy, N.S. (1983) Minocycline reduces gingival collagenolytic activity during diabetes. J. Period. Res., 18:516-526.
22. Golub, L.M., Ramamurthy, N.S., McNamara, T.F., Gomes, B., Wolff, M., Casino, A., Kapoor, A., Zambon, J., Ciancio, S., Schneir, M., and Perry, H. (1984) Tetracyclines inhibit tissue collagenase activity. J. Period. Res., 19:651-655.
23. Golub, L.M., Ramamurthy, N.S., Kaneko, H., Rifkin, B., and McNamara, T.F. (1990) Tetracycline administration prevents diabetes-induced osteopenia in the rat: Initial observations. Res. Commun. Chem. Pathol. Pharmacol., 68:27-40.
24. Golub, L.M., Wolff, M., Lee, H.M., McNamara, T.F., Ramamurthy, N.S., Zambon, J., and Cianco, S. (1985) Further evidence that tetracyclines inhibit collagenase activity in human crevicular fluid and from other mammalian sources. J. Period. Res., 20:12-23.
25. Golub, L.M., McNamara, T.F., d'Angelo, G., Greenwald, R.A., and Ramamurthy, N.S. (1987) A non-antibacterial chemically-modified tetracycline inhibits mammalian collagenase activity. J. Dent. Res., 66:1310-1314.
26. Gomes, B.C., Golub, L.M., and Ramamuthy, N.S. (1984) Tetracyclines inhibit parathyroid-induced bone resorption in organ culture. Experientia, 40:1273-1275.
27. Goto, T., Tsukuba, T., Kiyoshima, T., Nishimura, Y., Kato, K., Yamamoto, K., and Tanaka, T. (1993) Immunohistochemical localization of cathepsin-B, D and L in the rat osteoclast. Histochemistry, 99:411-414.
28. Grevstad, H.J. (1993) Doxycycline prevents root resorption and alveolar bone loss in rats after periodontal surgery. Scand. J. Dent. Res., 101:287-291.
29. Hamilton, J.A., Lingelbach, S.R., Partridge, N.C., and Martin, T.J. (1984) Stimulation of plasminogen activator in osteoblast-like cells by bone resorbing hormones. Biochem. Biophys. Res. Commun., 122:230-236.
30. Heath, J.K., Reynolds, J.J., and Meikle, M.C. (1990) Osteopetrotic (grey-lethal) bone produces collagenase and TIMP in organ culture: Regulation by vitamin A. Biochem. Biophys. Commun. Res., 168:1171-1176.
31. Hill, P.A., Murphy, G., Docherty, A.J.P., Hembry, K.M., Millican, T.A., Reynolds, J.J., and Meikle, M.C. (1994) The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts. J. Cell Sci., 107:3055-3064.
32. Hoekman, K., Löwik, C.W.G.M., Vanderruit, M., Bijvoet, O.L.M., Verheijen, J.H., and Papapoulos, S.E. (1991) Regulation of the production of plasminogen activators by bone resorption enhancing and inhibiting factors in three types of osteoblast-like cells. Bone Miner., 14:189-204.
33. Jilka, R.L. (1989) Procollagenase associated with the noncalcified matrix of bone and its regulation by parathyroid hormone. Bone, 10:353-358.
34. Jilka, R.L., and Hamilton, J.W. (1984) Involvement of nonosteoclastic cells in hormone-regulated collagenolysis in bone. In: Endocrine Control of Bone and Calcium Metabolism. D.V. Cohn, T. Fujita, J.T. Potts, and R.V. Talmage, eds. Elsevier, Amsterdam, Vol. 8A, pp. 136-139.
35. Jilka, R.L., and Hamilton, J.W. (1985) Evidence for two pathways for stimulation of collagenolysis in bone. Calcif. Tissue Res., 37:300-306.
36. Klapisz-Wolikow, M., and Saffar, J.L. (1986) Etude d'une séquence de remaniement expérimental induite sur le périoste mandibulaire du rat. J. Biol. Buccale, 14:263-271.
37. Malone, J.D., Teitelbaum, S.L., Griffin, G.L., Senior, R.M., and Kahn, A.J. (1982) Recruitment of osteoclast precursors by purified bone matrix constituents. J. Cell Biol., 92:227-230.
38. Marotti, G. (1977) Decrement in volume of osteoblasts during osteon formation and its effect on the size of the corresponding osteocytes. In: Bone Histomorphometry. P.J. Meunier, ed. Armour Montagu, Paris, Vol. 2, pp. 385-398.
39. Martin, T.J., Allan, E.H., and Fukumoto, S. (1993) The plasminogen activator and inhibitor system in bone remodeling. Growth Regul., 3:209-214.
40. Miller, S.C., de Saint Georges, L., Bowman, B.M., and Jee, W.S.S. (1989) Bone lining cells: Structure and function. Scanning Microsc., 3:953-961.
41. Moonga, B.S., Moss, D.W., Patchell, A., and Zaidi, M. (1990) Intracellular regulation of enzyme secretion from rat osteoclasts and evidence for a functional role in bone resorption. J. Physiol., 429:29-45.
42. Neidle, E.A., Kroeger, D.C., and Yagiela, J.A. (1985) Tetracyclines. In: Pharmacology and Therapeutics for Dentistry. E.H. Montgomery, ed. Mosby, St. Louis, pp. 539-592.
43. Okamura, T., Shimokawa, H., Takagi, Y., Ono, H., and Sasaki, S. (1993) Detection of collagenase messenger RNA in odontoclasts of bovine root-resorbing tissue by insitu hybridization. Calcif. Tissue Int., 52:325-330.
44. Otsuka, K., Sodek, J., and Limeback, H.F. (1984) Synthesis of collagenase and collagenase inhibitors by osteoblast-like cells in culture. Eur. J. Biochem., 145:123-129.
45. Quinn, C.O., Scott, D.K., Brinckerhoff, C.E., Matrisian, L.M., Jeffrey, J.J., and Partridge, N.C. (1990) Rat collagenase - cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J. Biol. Chem., 265:22342-22347.
46. Ramamurthy, N.S., Vernillo, A.T., Lee, H.M., Golub, L.M., and Rifkin, B.R. (1990) The effect of tetracyclines on collagenase activity in UMR 106-01 rat osteoblastic osteosarcoma cells. Res. Commun. Chem. Pathol. Pharmacol., 70:323-335.
47. Ramamurthy, N.S., Vernillo, A.T., Greenwald, R.A., Lee, H.M., Sorsa, T., Golub, L.M., and Rifkin, B.R. (1993) Reactive oxygen species activate and tetracyclines inhibit rat osteoblast collagenase. J. Bone Miner. Res., 8:1247-1253.
48. Rifkin, B.R., Vernillo, A.T., Kleckner, A.P., Auszmann, J.M., Rosenberg, L.R., and Zimmerman, M. (1991) Cathepsin-B and cathepsin-L activities in isolated osteoclasts. Biochem. Biophys. Res. Commun., 179:63-69.
49. Rifkin, B., Ramamurthy, N.S., and Gay, C.V. (1992) Effects of tetracyclines on acid production by isolated osteoclasts. J. Dent. Res., 71:235.
50. Rifkin, B.R., Vernillo, A.T., and Golub, L.M. (1993) Blocking periodontal disease progression by inhibiting tissue-destructive enzymes - a potential therapeutic role for tetracyclines and their chemically-modified analogs. J. Periodontol., 64:819-827.
51. Rifkin, B.R., Vernillo, A.T., Golub, L.M., and Ramamurthy, N.S. (1994) Modulation of bone resorption by tetracyclines. In: Inhibition of Matrix Metalloproteinases. Therapeutic Potential. Ann. N.Y. Acad. Sci., 732:165-180.
52. Rodan, G.A., and Martin, T.J. (1981) Role of osteoblasts in hormonal control of bone resorption. A hypothesis. Calcif. Tissue Int., 33:349-351.
53. Saffar, J.L., and Klapisz-Wolikow, M. (1990) Changes in mast cell number during the activation phase of an induced synchronized remodeling sequence in the rat. Bone, 11:369-372.
54. Saffar, J.L., and Leroux, P. (1988) Role of prostaglandins in bone resorption in a synchronized remodeling sequence in the rat. Bone, 9:141-145.
55. Sakamoto, M., and Sakamoto, S. (1984a) Immunocytochemical localization of collagenase in isolated mouse bone cells. Biomed. Res., 5:29-38.
56. Sakamoto, S., and Sakamoto, M. (1984b) Isolation and characterization of collagenase synthesized by mouse bone cells in culture. Biomed. Res., 5:39-46.
57. Sasaki, T., Kaneko, H., Ramamurthy, N.S., and Golub, L.M. (1991) Tetracycline administration restores osteoblast structure and function during experimental diabetes. Anat. Rec., 231:25-34.
58. Schneir, M., Ramamurthy, N., and Golub, L. (1990) Minocycline-treatment of diabetic rats normalizes skin collagen production and mass: Possible causative mechanisms. Matrix, 10:112-113.
59. Thomson, B.M., Atkinson, S.J., McGarrity, A.M., Hembry, R.M., Reynolds, J.J., and Meikle, M.C. (1989) Type I collagen degradation by mouse calvarial osteoblasts stimulated with 1,25-dihydroxyvitamin D-3: Evidence for a plasminogen-plasmin-metalloproteinase activation cascade. Biochim. Biophys. Acta, 1014:125-132.
60. Tran Van, P., Vignery, A., and Baron, R. (1982) Cellular kinetics of the bone remodeling sequence in the rat. Anat. Rec., 202:445-451.
61. Vaes, G. (1988) Cellular biology and biochemical mechanism of bone resorption. A review of recent developments on the formation, activation, and mode of action of osteoclasts. Clin. Orthop., 231:239-271.
62. Zaidi, M., Moonga, B.S., Huang, C.L.H., Alam, A.S.M.T., Shankar, V.S., Pazianas, M., Eastwood, J.B., Datta, H.K., and Rifkin, B.R. (1993a) The effect of tetracyclines on quantitative measures of osteoclast morphology. Biosci. Rep., 13:175-182.
63. 2+ sensing by the osteoclast. Cell Calcium, 14:271-277.